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    In situ detoxification of fermentation inhibitors with reducing agents
    1.
    发明授权
    In situ detoxification of fermentation inhibitors with reducing agents 有权
    用还原剂原位解毒发酵抑制剂

    公开(公告)号：US08815499B2

    公开(公告)日：2014-08-26

    申请号：US13517250

    申请日：2010-12-17

    申请人： Björn Alriksson ,  Leif Jönsson ,  Sune Wännström

    发明人： Björn Alriksson ,  Leif Jönsson ,  Sune Wännström

    IPC分类号： C12Q3/00 ,  C12P7/16 ,  C12N1/38 ,  C12P7/46 ,  C12P7/10

    CPC分类号： C12P7/10 ,  C12N1/38 ,  C12P7/16 ,  C12P7/46 ,  C12P2203/00 ,  Y02E50/10 ,  Y02E50/16 ,  Y10S435/813

    摘要： The present invention provides a method for decreasing the fermentation inhibition in a fermentation of cellulose-derived material in a fermentor, wherein fermentation inhibitory properties of the material subjected to fermentation is decreased by an addition of at least one reducing agent to the fermentor. Further, there is provided a method of increasing the fermentability of a fermentation process comprising the steps of measuring the fermentability of the fermentation process and if the fermentability is below a reference value, then adding at least one reducing agent to the fermentation process.

    摘要翻译： 本发明提供一种用于降低发酵罐中纤维素衍生物质的发酵发酵抑制的方法，其中通过向发酵罐中加入至少一种还原剂来降低发酵物质的发酵抑制性能。 此外，提供了一种增加发酵方法的发酵能力的方法，包括以下步骤：测量发酵过程的发酵能力，如果发酵能力低于参考值，则在发酵过程中加入至少一种还原剂。

    In Situ Detoxification of Fermentation Inhibitors with Reducing Agents
    2.
    发明申请
    In Situ Detoxification of Fermentation Inhibitors with Reducing Agents 有权
    用还原剂发酵抑制剂的原位解毒

    公开(公告)号：US20130022958A1

    公开(公告)日：2013-01-24

    申请号：US13517250

    申请日：2010-12-17

    申请人： Björn Alriksson ,  Leif Jönsson ,  Sune Wännström

    发明人： Björn Alriksson ,  Leif Jönsson ,  Sune Wännström

    IPC分类号： C12Q3/00

    CPC分类号： C12P7/10 ,  C12N1/38 ,  C12P7/16 ,  C12P7/46 ,  C12P2203/00 ,  Y02E50/10 ,  Y02E50/16 ,  Y10S435/813

    摘要： The present invention provides a method for decreasing the fermentation inhibition in a fermentation of cellulose-derived material in a fermentor, wherein fermentation inhibitory properties of the material subjected to fermentation is decreased by an addition of at least one reducing agent to the fermentor. Further, there is provided a method of increasing the fermentability of a fermentation process comprising the steps of measuring the fermentability of the fermentation process and if the fermentability is below a reference value, then adding at least one reducing agent to the fermentation process.

    摘要翻译： 本发明提供一种用于降低发酵罐中纤维素衍生物质的发酵发酵抑制的方法，其中通过向发酵罐中加入至少一种还原剂来降低发酵物质的发酵抑制性能。 此外，提供了一种增加发酵方法的发酵能力的方法，包括以下步骤：测量发酵过程的发酵能力，如果发酵能力低于参考值，则在发酵过程中加入至少一种还原剂。

    Detoxification with reducing agents
    3.
    发明授权
    Detoxification with reducing agents 有权
    还原剂解毒

    公开(公告)号：US08795997B2

    公开(公告)日：2014-08-05

    申请号：US13517284

    申请日：2010-12-17

    申请人： Leif Jönsson ,  Björn Alriksson ,  Adnan Cavka

    发明人： Leif Jönsson ,  Björn Alriksson ,  Adnan Cavka

    IPC分类号： C12P7/10

    CPC分类号： C12P7/10 ,  C12N1/38 ,  C12P19/14 ,  C12P2203/00 ,  Y02E50/16

    摘要： The present invention provides a method for decreasing the fermentation inhibition in a process for producing a target chemical from a pretreated cellulosic material, the process comprising enzymatic hydrolysis of the pretreated cellulosic material and fermentation of hydrolysed material, wherein the fermentation inhibitory properties of the material subjected to fermentation is decreased by an addition of at least one reducing agent to the pretreated material or hydrolysed material. Moreover, the present invention provides the use of dithionite for decreasing the fermentation inhibitory properties of a material being subjected to simultaneous enzymatic hydrolysis and fermentation.

    摘要翻译： 本发明提供了一种降低由预处理的纤维素材料生产目标化学物质的方法中的发酵抑制的方法，该方法包括预处理的纤维素材料的酶水解和水解材料的发酵，其中所述材料的发酵抑制性质 通过向预处理的材料或水解材料中加入至少一种还原剂来降低发酵。 此外，本发明提供连二亚硫酸盐用于降低同时进行酶水解和发酵的材料的发酵抑制性质的用途。

    Detoxification with Reducing Agents
    5.
    发明申请
    Detoxification with Reducing Agents 有权
    减毒剂排毒

    公开(公告)号：US20130011894A1

    公开(公告)日：2013-01-10

    申请号：US13517284

    申请日：2010-12-17

    申请人： Leif Jönsson ,  Björn Alriksson ,  Adnan Cavka

    发明人： Leif Jönsson ,  Björn Alriksson ,  Adnan Cavka

    IPC分类号： C12P7/14

    CPC分类号： C12P7/10 ,  C12N1/38 ,  C12P19/14 ,  C12P2203/00 ,  Y02E50/16

    摘要： The present invention provides a method for decreasing the fermentation inhibition in a process for producing a target chemical from a pretreated cellulosic material, the process comprising enzymatic hydrolysis of the pretreated cellulosic material and fermentation of hydrolysed material, wherein the fermentation inhibitory properties of the material subjected to fermentation is decreased by an addition of at least one reducing agent to the pretreated material or hydrolysed material. Moreover, the present invention provides the use of dithionite for decreasing the fermentation inhibitory properties of a material being subjected to simultaneous enzymatic hydrolysis and fermentation.

    摘要翻译： 本发明提供了一种降低由预处理的纤维素材料生产目标化学物质的方法中的发酵抑制的方法，该方法包括预处理的纤维素材料的酶水解和水解材料的发酵，其中所述材料的发酵抑制性质 通过向预处理的材料或水解材料中加入至少一种还原剂来降低发酵。 此外，本发明提供连二亚硫酸盐用于降低同时进行酶水解和发酵的材料的发酵抑制性质的用途。

    Fermentation process starting from cellulosic biomass and involving the recirculation of detoxified stillage into the process
    6.
    发明授权
    Fermentation process starting from cellulosic biomass and involving the recirculation of detoxified stillage into the process 有权
    发酵过程从纤维素生物质开始，并涉及将无毒废渣再循环到该过程中

    公开(公告)号：US08110383B2

    公开(公告)日：2012-02-07

    申请号：US13121611

    申请日：2009-09-30

    申请人： Leif Jönsson ,  Björn Alriksson

    发明人： Leif Jönsson ,  Björn Alriksson

    IPC分类号： C12P7/06 ,  C12P7/04

    CPC分类号： C12P7/10 ,  Y02E50/16 ,  Y02E50/17

    摘要： A method for preparing a target chemical derivable from cellulosic biomass, involving detoxification of spent hydrolysate is provided. The method comprises the steps of providing cellulosic biomass, subjecting the cellulosic biomass to aqueous pretreatment, aqueous hydrolysis, and fermentation under conditions in which at least a part of the fermentable sugars are fermented into a primary target chemical, separating the primary target chemical from the fermented hydrolysate to provide a spent hydrolysate comprising inhibitory substances and detoxifying the spent hydrolysate by decreasing the concentration of at least one of the inhibitory substances using a detoxification biocatalyst selected from the group consisting of wild type, mutant and recombinant filamentous fungi and recirculating at least a part of the detoxified spent hydrolysate, optionally after further purification.

    摘要翻译： 提供了一种制备可从纤维素生物质衍生的目标化学物质的方法，涉及废水解产物的解毒。 该方法包括以下步骤：提供纤维素生物质，将纤维素生物质进行水性预处理，水解水解和发酵，其中至少一部分可发酵糖被发酵成主要目标化学品，将主要目标化学物质与 发酵的水解产物，以提供包含抑制物质的废水解产物，并通过使用选自野生型，突变型和重组丝状真菌的解毒生物催化剂，通过降低至少一种抑制物质的浓度来解毒废水解产物，并再循环至少一种 任选地在进一步纯化后的一部分解毒的废水解产物。

    FERMENTATION PROCESS STARTING FROM CELLULOSIC BIOMASS AND INVOLVING THE RECIRCULATION OF DETOXIFIED STILLAGE INTO THE PROCESS
    7.
    发明申请
    FERMENTATION PROCESS STARTING FROM CELLULOSIC BIOMASS AND INVOLVING THE RECIRCULATION OF DETOXIFIED STILLAGE INTO THE PROCESS 有权
    发酵过程从细胞生物量开始并涉及到将过氧化还原酶再循环进入过程

    公开(公告)号：US20110217746A1

    公开(公告)日：2011-09-08

    申请号：US13121611

    申请日：2009-09-30

    申请人： Leif Jönsson ,  Björn Alriksson

    发明人： Leif Jönsson ,  Björn Alriksson

    IPC分类号： C12P7/10 ,  C12P1/00 ,  C12M1/00 ,  A62D3/02

    CPC分类号： C12P7/10 ,  Y02E50/16 ,  Y02E50/17

    摘要： A method for preparing a target chemical derivable from cellulosic biomass, involving detoxification of spent hydrolysate is provided. The method comprises the steps of providing cellulosic biomass, subjecting the cellulosic biomass to aqueous pretreatment, aqueous hydrolysis, and fermentation under conditions in which at least a part of the fermentable sugars are fermented into a primary target chemical, separating the primary target chemical from the fermented hydrolysate to provide a spent hydrolysate comprising inhibitory substances and detoxifying the spent hydrolysate by decreasing the concentration of at least one of the inhibitory substances using a detoxification biocatalyst selected from the group consisting of wild type, mutant and recombinant filamentous fungi and recirculating at least a part of the detoxified spent hydrolysate, optionally after further purification.

    摘要翻译： 提供了一种制备可从纤维素生物质衍生的目标化学物质的方法，涉及废水解产物的解毒。 该方法包括以下步骤：提供纤维素生物质，将纤维素生物质进行水性预处理，水解水解和发酵，其中至少一部分可发酵糖被发酵成主要目标化学品，将主要目标化学物质与 发酵的水解产物，以提供包含抑制物质的废水解产物，并通过使用选自野生型，突变型和重组丝状真菌的解毒生物催化剂，通过降低至少一种抑制物质的浓度来解毒废水解产物，并再循环至少一种 任选地在进一步纯化后的一部分解毒的废水解产物。