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公开(公告)号:US20210071124A1
公开(公告)日:2021-03-11
申请号:US16920365
申请日:2020-07-02
Applicant: Berkeley Lights, Inc.
Inventor: Randall D. LOWE, JR. , Kristin G. BEAUMONT , Aathavan KARUNAKARAN , Natalie C. MARKS , Jason M. MCEWEN , Mark P. WHITE , J. Tanner NEVILL , Gang F. WANG , Andrew W. MCFARLAND , Daniele Malleo , Keith J. BREINLINGER , Xiao GUAN , Kevin T. CHAPMAN
Abstract: Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.
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公开(公告)号:US20230242860A1
公开(公告)日:2023-08-03
申请号:US17936478
申请日:2022-09-29
Applicant: Berkeley Lights, Inc.
Inventor: Russell A. NEWSTROM , Andrew W. MCFARLAND , Darcy K. KELLY-GREENE , J. Tanner NEVILL , Gang F. WANG
CPC classification number: C12M41/14 , C12M23/12 , C12M23/38 , C12M23/46 , C12M37/04 , C12M41/22 , C12M41/32 , C12M41/34 , C12M41/48
Abstract: Incubators including an enclosure with an internal chamber configured to support a cell culture plate comprising a plurality of wells are disclosed. The enclosure includes a plurality of openings configured to allow access to the wells. The incubators include a sealing element configured to seal the plurality of openings in the enclosure. The sealing element comprises a plurality of openings corresponding to at least a subset of the plurality of openings in the enclosure. Access to the internal chamber can be provided by aligning the plurality of openings in the sealing element with the plurality of openings in the enclosure. Methods for using the incubators are also provided.
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公开(公告)号:US20220356429A1
公开(公告)日:2022-11-10
申请号:US17743318
申请日:2022-05-12
Applicant: Berkeley Lights, Inc.
Inventor: Randall D. LOWE, JR. , Kristin G. BEAUMONT , Aathavan KARUNAKARAN , Natalie C. MARKS , Jason M. MCEWEN , Mark P. WHITE , J. Tanner NEVILL , Gang F. WANG , Andrew W. MCFARLAND , Daniele Malleo , Keith J. BREINLINGER , Xiao GUAN , Kevin T. CHAPMAN
Abstract: Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.
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公开(公告)号:US20170114316A1
公开(公告)日:2017-04-27
申请号:US15282923
申请日:2016-09-30
Applicant: Berkeley Lights, Inc.
Inventor: Russell A. NEWSTROM , Andrew W. MCFARLAND , Darcy K. KELLY-GREENE , J. Tanner NEVILL , Gang F. WANG
CPC classification number: C12M41/14 , C12M23/12 , C12M23/38 , C12M23/46 , C12M37/04 , C12M41/22 , C12M41/32 , C12M41/34 , C12M41/48
Abstract: Incubators including an enclosure with an internal chamber configured to support a cell culture plate comprising a plurality of wells are disclosed. The enclosure includes a plurality of openings configured to allow access to the wells. The incubators include a sealing element configured to seal the plurality of openings in the enclosure. The sealing element comprises a plurality of openings corresponding to at least a subset of the plurality of openings in the enclosure. Access to the internal chamber can be provided by aligning the plurality of openings in the sealing element with the plurality of openings in the enclosure. Methods for using the incubators are also provided.
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公开(公告)号:US20220250071A1
公开(公告)日:2022-08-11
申请号:US17534350
申请日:2021-11-23
Applicant: Berkeley Lights, Inc.
Inventor: Troy A. LIONBERGER , Matthew E. FOWLER , Phillip J. M. ELMS , Kevin D. LOUTHERBACK , Randall D. LOWE, JR. , Jian GONG , J. Tanner NEVILL , Gang F. WANG , Gregory G. LAVIEU , John A. TENNEY , Aathavan KARUNAKARAN , Anupam SINGHAL , I-Jong LIN
Abstract: Methods, systems and kits are described herein for detecting the results of an assay. In particular, the methods, systems and devices of the present disclosure rely on a difference between the diffusion rates of a reporter molecule and an analyte of interest in order to quantify an amount of analyte in a microfluidic device. The analyte may be a secreted product of a biological micro-object.
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公开(公告)号:US20190240665A1
公开(公告)日:2019-08-08
申请号:US16160816
申请日:2018-10-15
Applicant: Berkeley Lights, Inc.
Inventor: Troy A. LIONBERGER , Matthew E. FOWLER , Phillip J. M. ELMS , Kevin D. LOUTHERBACK , Randall D. LOWE, JR. , Jian GONG , Tanner J. NEVILL , Gang F. WANG , Gregory G. LAVIEU , John A. TENNEY , Aathavan KARUNAKARAN
CPC classification number: B01L3/502761 , B01L9/527 , B01L2300/0829 , B03C5/005 , B03C5/026 , B03C2201/26 , G01N21/05 , G01N21/6452 , G01N21/6458 , G01N2201/0675 , G06T7/0014
Abstract: Methods, systems and kits are described herein for detecting the results of an assay. In particular, the methods, systems and devices of the present disclosure rely on a difference between the diffusion rates of a reporter molecule and an analyte of interest in order to quantify an amount of analyte in a microfluidic device. The analyte may be a secreted product of a biological micro-object.
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