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20 条记录 (耗时 0.021 秒)

    Method for Modifying the Refractive Index of Ocular Tissues
    1.
    发明申请
    Method for Modifying the Refractive Index of Ocular Tissues 审中-公开
    修改眼组织折射率的方法

    公开(公告)号：US20130226162A1

    公开(公告)日：2013-08-29

    申请号：US13789762

    申请日：2013-03-08

    申请人： University of Rochester ,  Bausch & Lomb Incorporated

    发明人： Wayne H. Knox ,  Krystel R. Huxlin ,  Jay F. Kunzler ,  Li Ding

    IPC分类号： A61F9/008

    CPC分类号： A61F9/00804 ,  A61F9/008 ,  A61F9/00829 ,  A61F2009/00842 ,  A61F2009/00848 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088

    摘要： A laser system for changing the index of refraction of cornea tissue in a living eye. The laser system comprises a laser that provides laser pulses with a wavelength from 400 nm to 900 nm and a pulse energy from 0.01 nJ to 10 nJ, and a control device for setting the operating parameters of the laser below an optical breakdown threshold of the tissue to avoid photo-disruption and tissue destruction of the tissue, and to direct the laser pulses at the cornea tissue resulting in a change in the index of refraction of the tissue within regions irradiated by the laser pulses.

    摘要翻译： 用于改变活眼中角膜组织折射指数的激光系统。 激光系统包括提供波长为400nm至900nm的激光脉冲和0.01nJ至10nJ的脉冲能量的激光器，以及用于将激光器的操作参数设置在组织的光学击穿阈值以下的控制装置 以避免组织的光破坏和组织破坏，并将激光脉冲引导到角膜组织，导致由激光脉冲照射的区域内的组织的折射率的变化。

    Optical Material and Method for Modifying the Refractive Index
    2.
    发明申请
    Optical Material and Method for Modifying the Refractive Index 审中-公开
    用于改变折射率的光学材料和方法

    公开(公告)号：US20130178934A1

    公开(公告)日：2013-07-11

    申请号：US13782257

    申请日：2013-03-01

    申请人： Bausch & Lomb Incorporated ,  University of Rochester

    发明人： Wayne H. Knox ,  Li Ding ,  Jay F. Kunzler ,  Dharmendra M. Jani

    IPC分类号： A61F2/16 ,  A61F9/008

    CPC分类号： A61F2/1624 ,  A61F2/16 ,  A61F2/1627 ,  A61F2/1635 ,  A61F9/008 ,  A61F9/00834 ,  A61F2009/00842 ,  A61F2009/00897 ,  G02C7/04 ,  G02C2202/14

    摘要： A laser system for modifying the index of refraction of an optical hydrogel material. The laser system comprises a computer program to determine the position and shape of refractive structures to be written into the optical hydrogel material to correct a patient's vision, and a focused laser that generates laser light having a wavelength of from 400 nm to 900 nm, and which operates with an average power of 10 mW to 1000 mW to produce a pulse energy from 0.05 nJ to 1000 nJ with a peak intensity at focus of greater than 1013 W/cm2. The refractive structures exhibit a change in the index of refraction of 0.01 to 0.06 in the optical hydrogel material.

    摘要翻译： 一种用于改变光学水凝胶材料的折射率的激光系统。 激光系统包括计算机程序，以确定要写入光学水凝胶材料的折射结构的位置和形状以校正患者的视力;以及聚焦激光，其产生波长为400nm至900nm的激光，以及 其以10mW至1000mW的平均功率工作，以产生从0.05nJ到1000nJ的脉冲能量，并且焦点处的峰值强度大于1013W / cm 2。 折射结构在光学水凝胶材料中表现出0.01至0.06的折射率变化。

    Method for modifying the refractive index of ocular tissues
    3.
    发明授权
    Method for modifying the refractive index of ocular tissues 有权
    改变眼组织折射率的方法

    公开(公告)号：US08512320B1

    公开(公告)日：2013-08-20

    申请号：US13789755

    申请日：2013-03-08

    申请人： University of Rochester ,  Bausch & Lomb Incorporated

    发明人： Wayne H. Knox ,  Krystel R. Huxlin ,  Jay F. Kunzler ,  Li Ding

    IPC分类号： A61B18/18

    CPC分类号： A61F9/00804 ,  A61F9/008 ,  A61F9/00829 ,  A61F2009/00842 ,  A61F2009/00848 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088

    摘要： The invention is directed to a method for correcting vision in a patient by modifying the refractive index of cornea tissue. The method comprises identifying and measuring the degree of vision correction of the patient; and determining the position and type of refractive structures to be written into the cornea tissue of the patient to correct the patient's vision. The refractive structures are written by irradiating select regions of the cornea tissue with focused laser pulses having a wavelength from 400 nm to 900 nm and a pulse energy from 0.01 nJ to 10 nJ. The refractive structures are characterized by a positive change in refractive index in relation to non-irradiated cornea tissue of the patient.

    摘要翻译： 本发明涉及通过改变角膜组织的折射率来校正患者视力的方法。 该方法包括识别和测量患者的视力矫正程度; 以及确定要写入患者的角膜组织中的折射结构的位置和类型以校正患者的视力。 通过用波长为400nm至900nm的聚焦激光脉冲和0.01nJ至10nJ的脉冲能量照射角膜组织的选择区域来写入折射结构。 折射结构的特征在于与患者的未照射的角膜组织相关的折射率的正变化。

    Ethylenically unsaturated polymerizable groups comprising polycarbosiloxane monomers
    7.
    发明授权
    Ethylenically unsaturated polymerizable groups comprising polycarbosiloxane monomers 有权
    包含聚碳硅氧烷单体的烯键式不饱和可聚合基团

    公开(公告)号：US09039174B2

    公开(公告)日：2015-05-26

    申请号：US13841145

    申请日：2013-03-15

    申请人： Bausch & Lomb Incorporated

    发明人： Alok Kumar Awasthi ,  Jay F. Kunzler

    IPC分类号： C08F30/08 ,  C07F7/08 ,  C08G77/50 ,  C08G77/20

    CPC分类号： C08F30/08 ,  C07F7/0838 ,  C08G77/20 ,  C08G77/50

    摘要： The present application relates to novel monomers comprising polycarbosiloxane monomers useful in certain specific embodiments in the manufacture of devices. More particularly, the present application relates to certain ethylenically unsaturated free radical polymerizable monomers comprising polycarbosiloxane monomers. Even more particularly, the present application pertains to monomers comprising polycarbosiloxane monomers which further comprise at least two ethylenically unsaturated free radical polymerizable groups.

    摘要翻译： 本申请涉及包含聚碳硅氧烷单体的新型单体，其在制造装置的某些具体实施方案中是有用的。 更具体地，本申请涉及包含聚碳硅氧烷单体的某些烯键式不饱和自由基可聚合单体。 甚至更具体地，本申请涉及包含聚碳硅氧烷单体的单体，其还包含至少两个烯键式不饱和可自由基聚合基团。

    Sterilization of intraocular lenses
    8.
    发明授权
    Sterilization of intraocular lenses 有权
    人工晶状体的灭菌

    公开(公告)号：US08753389B1

    公开(公告)日：2014-06-17

    申请号：US13666051

    申请日：2012-11-01

    申请人： Bausch & Lomb Incorporated

    发明人： Jay F. Kunzler

    IPC分类号： A61F2/16 ,  B65D85/38 ,  A61B17/06 ,  B29D11/00

    CPC分类号： B29D11/00125 ,  A61L12/04 ,  B29D11/0025

    摘要： A packaged, sterilized intraocular lens prepared by a process comprising providing a hydrophobic acrylic, or low water acrylic, intraocular lens and positioning the acrylic lens in a lens enclosure with an aqueous solution to provide a lens package. The lens package is then heated to a temperature sufficient for sterilization, however, the heating of the lens package must begin before the acrylic lens reaches an equilibrated, hydrated state following contact of the lens with the aqueous solution. The resulting sterilized acrylic intraocular lens will have less than sixty percent of total volume of disc-like features, or less than forty percent of total volume of water vacuoles, after 60 days following sterilization compared to an acrylic lens of the same composition, which was sterilized under the same conditions, but in an equilibrated, hydrated state.

    摘要翻译： 一种通过包括提供疏水丙烯酸或低水丙烯酸眼内透镜并将丙烯酸镜片定位在具有水溶液的透镜外壳中以提供镜片包装的方法制备的包装的无菌眼内透镜。 然后将透镜包装加热到足以灭菌的温度，然而，在透镜与水溶液接触之后，在丙烯酸镜片达到平衡的水合状态之前，必须开始对透镜包装的加热。 与相同成分的丙烯酸类镜片相比，得到的无菌丙烯酸类眼内透镜在灭菌后60天内具有小于盘状特征总体积的百分之六十，或少于总液体体积的百分之四十， 在相同条件下灭菌，但处于平衡的水合状态。

    ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUPS COMPRISING POLYCARBOSILOXANE MONOMERS
    10.
    发明申请
    ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUPS COMPRISING POLYCARBOSILOXANE MONOMERS 有权
    包含聚碳酸酯单体的乙烯不饱和聚合物组合

    公开(公告)号：US20130289294A1

    公开(公告)日：2013-10-31

    申请号：US13841145

    申请日：2013-03-15

    申请人： Bausch & Lomb Incorporated

    发明人： Alok Kumar Awasthi ,  Jay F. Kunzler

    IPC分类号： C08F30/08

    CPC分类号： C08F30/08 ,  C07F7/0838 ,  C08G77/20 ,  C08G77/50

    摘要： The present application relates to novel monomers comprising polycarbosiloxane monomers useful in certain specific embodiments in the manufacture of devices. More particularly, the present application relates to certain ethylenically unsaturated free radical polymerizable monomers comprising polycarbosiloxane monomers. Even more particularly, the present application pertains to monomers comprising polycarbosiloxane monomers which further comprise at least two ethylenically unsaturated free radical polymerizable groups.

    摘要翻译： 本申请涉及包含聚碳硅氧烷单体的新型单体，其在制造装置的某些具体实施方案中是有用的。 更具体地，本申请涉及包含聚碳硅氧烷单体的某些烯键式不饱和自由基可聚合单体。 甚至更具体地，本申请涉及包含聚碳硅氧烷单体的单体，其还包含至少两个烯键式不饱和可自由基聚合基团。