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公开(公告)号:US20210395920A1
公开(公告)日:2021-12-23
申请号:US17460513
申请日:2021-08-30
Applicant: Base Pair Biotechnologies, Inc.
Inventor: George W. Jackson , Robert Batchelor , Alexander S. Chiu , Rafal Drabek , Deepak Thirunavukarasu , Caitlin Bruns
IPC: C40B40/06 , C12Q1/6811 , C12Q1/6837
Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.
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公开(公告)号:US10920228B2
公开(公告)日:2021-02-16
申请号:US16262769
申请日:2019-01-30
Applicant: Base Pair Biotechnologies, Inc.
Inventor: George W. Jackson , Robert Batchelor , Alexander S. Chiu , Rafal Drabek , Deepak Thirunavukarasu
IPC: C12N15/11 , C12N15/115 , C12N15/10
Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as biocide molecules.
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公开(公告)号:US20190249245A1
公开(公告)日:2019-08-15
申请号:US16262777
申请日:2019-01-30
Applicant: Base Pair Biotechnologies, Inc.
Inventor: George W. Jackson , Robert Batchelor , Rafal Drabek , Caitlin Bruns
IPC: C12Q1/6874 , C12Q1/6806 , C12Q1/6837 , C12Q1/6876 , C12Q1/6848 , C40B30/04
CPC classification number: C12Q1/6874 , C12N15/1048 , C12N15/115 , C12N2310/16 , C12N2330/31 , C12Q1/6806 , C12Q1/6837 , C12Q1/6848 , C12Q1/6876 , C40B30/04
Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as lipoarabinomannan (LAM).
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公开(公告)号:US20240110237A1
公开(公告)日:2024-04-04
申请号:US18227386
申请日:2023-07-28
Applicant: BASE PAIR BIOTECHNOLOGIES, INC.
Inventor: Jasmine Kaur , Rafal Drabek , George W. Jackson , Robert Batchelor , Alexander Chiu
IPC: C12Q1/6874 , C12N15/10 , C12N15/115 , C12Q1/6806 , C12Q1/6837 , C12Q1/6848 , C12Q1/6876 , C40B30/04
CPC classification number: C12Q1/6874 , C12N15/1048 , C12N15/115 , C12Q1/6806 , C12Q1/6837 , C12Q1/6848 , C12Q1/6876 , C40B30/04 , C12N2310/16 , C12N2330/31
Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules.
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公开(公告)号:US20210348226A1
公开(公告)日:2021-11-11
申请号:US17152007
申请日:2021-01-19
Applicant: BASE PAIR BIOTECHNOLOGIES, INC.
Inventor: Jasmine Kaur , Rafal Drabek , George W. Jackson , Robert Batchelor , Alexander Chiu
IPC: C12Q1/6874 , C12N15/115 , C12N15/10 , C12Q1/6806 , C12Q1/6837 , C12Q1/6848 , C12Q1/6876 , C40B30/04
Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as opioids and opioid derivatives.
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公开(公告)号:US10927381B2
公开(公告)日:2021-02-23
申请号:US16677433
申请日:2019-11-07
Applicant: BASE PAIR BIOTECHNOLOGIES, INC.
Inventor: George W. Jackson , Robert Batchelor , Truong Nguyen , Victoria Singer , Garam Lee , Rafal Drabek
IPC: C07H21/00 , C12N15/115 , C40B30/04 , C40B10/00
Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as molecules used proteins or peptides, such as LL37.
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公开(公告)号:US20210041470A1
公开(公告)日:2021-02-11
申请号:US16832019
申请日:2020-03-27
Applicant: Base Pair Biotechnologies, Inc.
Inventor: Jasmine Kaur , Rafal Drabek , George W. Jackson , Robert Batchelor
Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as opioids and opioid metabolites.
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公开(公告)号:US11111603B2
公开(公告)日:2021-09-07
申请号:US16262825
申请日:2019-01-30
Applicant: Base Pair Biotechnologies, Inc.
Inventor: George W. Jackson , Robert Batchelor , Alexander S. Chiu , Rafal Drabek , Deepak Thirunavukarasu , Caitlin Bruns
IPC: C07H21/04 , C40B40/06 , C12Q1/6811 , C12Q1/6837
Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.
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公开(公告)号:US20190382766A1
公开(公告)日:2019-12-19
申请号:US16488239
申请日:2018-02-28
Applicant: Base Pair Biotechnologies, Inc.
Inventor: George W. Jackson , Robert Batchelor , Truong Nguyen , Rafal Drabek , Alexander S. Chiu , Deepak Thirunavukarasu , Vinoth Sankarapani
IPC: C12N15/115 , G01N33/53
Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as drug compounds, such as levamisole and cocaine.
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公开(公告)号:US20190233822A1
公开(公告)日:2019-08-01
申请号:US16262769
申请日:2019-01-30
Applicant: Base Pair Biotechnologies, Inc.
Inventor: George W. Jackson , Robert Batchelor , Alexander S. Chiu , Rafal Drabek , Deepak Thirunavukarasu
IPC: C12N15/115 , C12N15/10
CPC classification number: C12N15/115 , C12N15/1048 , C12N2310/16
Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as biocide molecules.
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