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    MICROFLUIDIC CARTRIDGES FOR ENHANCED AMPLIFICATION OF POLYNUCLEOTIDE-CONTAINING SAMPLES
    1.
    发明申请
    MICROFLUIDIC CARTRIDGES FOR ENHANCED AMPLIFICATION OF POLYNUCLEOTIDE-CONTAINING SAMPLES 有权

    公开(公告)号：US20220212190A1

    公开(公告)日：2022-07-07

    申请号：US17693773

    申请日：2022-03-14

    Applicant: BECTON, DICKINSON AND COMPANY

    Inventor： Rohini Rao ,  Joshua Keller ,  Song Chong ,  Thomas Dawidczyk ,  Karen L. Lenz ,  Joel Daniel Krayer ,  Edward Carrese

    IPC: B01L3/00

    Abstract: The technology described herein generally relates to microfluidic cartridges. The technology more particularly relates to a compressible pad applied to a microfluidic cartridge, wherein the microfluidic cartridge is configured to amplify nucleotides of interest, particularly from several biological samples in parallel, within microfluidic channels in the cartridge and permit detection of those nucleotides. Compressible pads of the present technology can be implemented in microfluidic cartridges having enhanced reaction chamber volumes, resulting in improved thermal uniformity and amplification efficiency in the cartridge. Assays using microfluidic cartridges of the present technology advantageously exhibit improved limit of detection (LOD) and improved limit of quantification (LOQ).

    Flow Sensor System
    3.
    发明申请
    Flow Sensor System 有权

    公开(公告)号：US20210228800A1

    公开(公告)日：2021-07-29

    申请号：US17159348

    申请日：2021-01-27

    Applicant: Becton, Dickinson and Company

    Inventor： Joel Daniel Krayer ,  Christopher Biagioli ,  Gary Ellerbusch ,  Kaushal Verma

    IPC: A61M5/168

    Abstract: A system may include a disposable flow sensor and a base for the disposable flow sensor. A method may include scanning, with an optical scanner of the base for the disposable flow sensor, a flow sensor label attached to the disposable flow sensor to decode a flow sensor identifier associated with the flow sensor, scanning, with the optical scanner of the base for the disposable flow sensor, a patient label attached to a patient to decode a patient identifier associated with the patient, and connecting the disposable flow sensor to the base.

    PIERCEABLE CAP
    9.
    发明申请
    PIERCEABLE CAP 有权

    公开(公告)号：US20230001417A1

    公开(公告)日：2023-01-05

    申请号：US17837401

    申请日：2022-06-10

    Applicant: BECTON, DICKINSON AND COMPANY

    Inventor： Ammon David Lentz ,  Kevin Bailey ,  Dustin Diemert ,  Joel Daniel Krayer ,  Laurence Michael Vaughan

    IPC: B01L3/00 ,  B65D51/00

    Abstract: A pierceable cap 11 may be used for containing sample specimens. The pierceable cap 11 may prevent escape of sample specimens before transfer with a transfer device 43. The pierceable cap 11 may fit over a vessel 21. An access port in the shell of the pierceable cap 11 may allow passage of a transfer device 43 through the pierceable cap 11. At least one frangible layer 215, 216 may be configured with cross slits 506 in a particular cross slit geometry. The cross slits 506 may contain an openable portion 644 or be covered by a thin membrane 645. The shell 610 and frangible layer(s) 215, 216 may be integrated into a one piece cap 601, or be separate components 634. The membrane on which the cross slits 506 are placed can be flat or contoured to guide the transfer device 43 to the cross slits 506.

    PIERCEABLE CAP
    10.
    发明申请
    PIERCEABLE CAP 审中-公开

    公开(公告)号：US20200094256A1

    公开(公告)日：2020-03-26

    申请号：US15372021

    申请日：2016-12-07

    Applicant: Becton, Dickinson and Company

    Inventor： Ammon David Lentz ,  Kevin Bailey ,  Dustin Diemert ,  Joel Daniel Krayer ,  Laurence Michael Vaughan

    IPC: B01L3/00 ,  B65D51/00

    Abstract: A pierceable cap 11 may be used for containing sample specimens. The pierceable cap 11 may prevent escape of sample specimens before transfer with a transfer device 43. The pierceable cap 11 may fit over a vessel 21. An access port in the shell of the pierceable cap 11 may allow passage of a transfer device 43 through the pierceable cap 11. At least one frangible layer 215, 216 may be configured with cross slits 506 in a particular cross slit geometry. The cross slits 506 may contain an openable portion 644 or be covered by a thin membrane 645. The shell 610 and frangible layer(s) 215, 216 may be integrated into a one piece cap 601, or be separate components 634. The membrane on which the cross slits 506 are placed can be flat or contoured to guide the transfer device 43 to the cross slits 506.

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