公开(公告)号：USD979092S1

公开(公告)日：2023-02-21

申请号：US29708021

申请日：2019-10-02

Applicant: BECTON, DICKINSON AND COMPANY

Designer： Joel Daniel Krayer ,  Song Chong ,  Edward Carrese ,  Karen L. Lenz ,  Rohini Rao ,  Joshua Keller ,  Thomas Dawidczyk

公开(公告)号：US11970692B2

公开(公告)日：2024-04-30

申请号：US17117471

申请日：2020-12-10

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Edward Carrese ,  Alexandre Daviet ,  Rohini Rao ,  Alyssa Shedlosky ,  Ben Hopwood ,  Dwight Livingston

IPC: C12N15/10 ,  B03C1/28 ,  C12Q1/6806

CPC classification number: C12N15/1013 ,  B03C1/288 ,  C12Q1/6806 ,  B03C2201/18 ,  B03C2201/26

Abstract: Disclosed herein are embodiments of a fixed magnet assembly that can be implemented into automated platforms for performing polynucleotide extraction from biological samples and preparing the polynucleotides into an amplification-ready form. The fixed magnet assembly can be used to provide magnetic energy to a container containing magnetic particles and a reaction mixture of polynucleotides, in order to bring about a separation of the magnetic particles from the reaction mixture. This can prevent or reduce magnetic particle carryover in the prepared amplification-ready sample, thereby improving amplification results.

公开(公告)号：US20220212190A1

公开(公告)日：2022-07-07

申请号：US17693773

申请日：2022-03-14

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Rohini Rao ,  Joshua Keller ,  Song Chong ,  Thomas Dawidczyk ,  Karen L. Lenz ,  Joel Daniel Krayer ,  Edward Carrese

IPC: B01L3/00

Abstract: The technology described herein generally relates to microfluidic cartridges. The technology more particularly relates to a compressible pad applied to a microfluidic cartridge, wherein the microfluidic cartridge is configured to amplify nucleotides of interest, particularly from several biological samples in parallel, within microfluidic channels in the cartridge and permit detection of those nucleotides. Compressible pads of the present technology can be implemented in microfluidic cartridges having enhanced reaction chamber volumes, resulting in improved thermal uniformity and amplification efficiency in the cartridge. Assays using microfluidic cartridges of the present technology advantageously exhibit improved limit of detection (LOD) and improved limit of quantification (LOQ).

公开(公告)号：USD1061935S1

公开(公告)日：2025-02-11

申请号：US29871329

申请日：2023-02-16

Applicant: BECTON, DICKINSON AND COMPANY

Designer： Joel Daniel Krayer ,  Song Chong ,  Edward Carrese ,  Karen L. Lenz ,  Rohini Rao ,  Joshua Keller ,  Thomas Dawidczyk

公开(公告)号：US20240279639A1

公开(公告)日：2024-08-22

申请号：US18647611

申请日：2024-04-26

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Edward Carrese ,  Alexandre Daviet ,  Rohini Rao ,  Alyssa Shedlosky ,  Ben Hopwood ,  Dwight Livingston

IPC: C12N15/10 ,  B03C1/28 ,  C12Q1/6806

CPC classification number: C12N15/1013 ,  B03C1/288 ,  C12Q1/6806 ,  B03C2201/18 ,  B03C2201/26

Abstract: Disclosed herein are embodiments of a fixed magnet assembly that can be implemented into automated platforms for performing polynucleotide extraction from biological samples and preparing the polynucleotides into an amplification-ready form. The fixed magnet assembly can be used to provide magnetic energy to a container containing magnetic particles and a reaction mixture of polynucleotides, in order to bring about a separation of the magnetic particles from the reaction mixture. This can prevent or reduce magnetic particle carryover in the prepared amplification-ready sample, thereby improving amplification results.

公开(公告)号：US20210180043A1

公开(公告)日：2021-06-17

申请号：US17117471

申请日：2020-12-10

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Edward Carrese ,  Alexandre Daviet ,  Rohini Rao ,  Alyssa Shedlosky ,  Ben Hopwood ,  Dwight Livingston

IPC: C12N15/10 ,  C12Q1/6806 ,  B03C1/28

Abstract: Disclosed herein are embodiments of a fixed magnet assembly that can be implemented into automated platforms for performing polynucleotide extraction from biological samples and preparing the polynucleotides into an amplification-ready form. The fixed magnet assembly can be used to provide magnetic energy to a container containing magnetic particles and a reaction mixture of polynucleotides, in order to bring about a separation of the magnetic particles from the reaction mixture. This can prevent or reduce magnetic particle carryover in the prepared amplification-ready sample, thereby improving amplification results.