公开(公告)号：US11970692B2

公开(公告)日：2024-04-30

申请号：US17117471

申请日：2020-12-10

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Edward Carrese ,  Alexandre Daviet ,  Rohini Rao ,  Alyssa Shedlosky ,  Ben Hopwood ,  Dwight Livingston

IPC: C12N15/10 ,  B03C1/28 ,  C12Q1/6806

CPC classification number: C12N15/1013 ,  B03C1/288 ,  C12Q1/6806 ,  B03C2201/18 ,  B03C2201/26

Abstract: Disclosed herein are embodiments of a fixed magnet assembly that can be implemented into automated platforms for performing polynucleotide extraction from biological samples and preparing the polynucleotides into an amplification-ready form. The fixed magnet assembly can be used to provide magnetic energy to a container containing magnetic particles and a reaction mixture of polynucleotides, in order to bring about a separation of the magnetic particles from the reaction mixture. This can prevent or reduce magnetic particle carryover in the prepared amplification-ready sample, thereby improving amplification results.

公开(公告)号：US20240279639A1

公开(公告)日：2024-08-22

申请号：US18647611

申请日：2024-04-26

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Edward Carrese ,  Alexandre Daviet ,  Rohini Rao ,  Alyssa Shedlosky ,  Ben Hopwood ,  Dwight Livingston

IPC: C12N15/10 ,  B03C1/28 ,  C12Q1/6806

CPC classification number: C12N15/1013 ,  B03C1/288 ,  C12Q1/6806 ,  B03C2201/18 ,  B03C2201/26

Abstract: Disclosed herein are embodiments of a fixed magnet assembly that can be implemented into automated platforms for performing polynucleotide extraction from biological samples and preparing the polynucleotides into an amplification-ready form. The fixed magnet assembly can be used to provide magnetic energy to a container containing magnetic particles and a reaction mixture of polynucleotides, in order to bring about a separation of the magnetic particles from the reaction mixture. This can prevent or reduce magnetic particle carryover in the prepared amplification-ready sample, thereby improving amplification results.

公开(公告)号：US20210180043A1

公开(公告)日：2021-06-17

申请号：US17117471

申请日：2020-12-10

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Edward Carrese ,  Alexandre Daviet ,  Rohini Rao ,  Alyssa Shedlosky ,  Ben Hopwood ,  Dwight Livingston

IPC: C12N15/10 ,  C12Q1/6806 ,  B03C1/28

Abstract: Disclosed herein are embodiments of a fixed magnet assembly that can be implemented into automated platforms for performing polynucleotide extraction from biological samples and preparing the polynucleotides into an amplification-ready form. The fixed magnet assembly can be used to provide magnetic energy to a container containing magnetic particles and a reaction mixture of polynucleotides, in order to bring about a separation of the magnetic particles from the reaction mixture. This can prevent or reduce magnetic particle carryover in the prepared amplification-ready sample, thereby improving amplification results.