-
公开(公告)号：US11598699B2
公开(公告)日：2023-03-07
申请号：US16994124
申请日：2020-08-14
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay
Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.
-
公开(公告)号：US20230164299A1
公开(公告)日：2023-05-25
申请号：US17981228
申请日：2022-11-04
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay , Laurent Kreplak
CPC classification number: H04N7/18 , G02B21/0008
Abstract: An imaging device includes light sensitive locations that are separately sensitive to light received at a surface with respect to a portion of a sample associated with the surface, the light sensitive locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface. The imaging device and a distance of the portion of the sample to the light sensitive locations are such that usable useful image of the portion of the sample can be acquired directly by operation of the imaging device.
An imaging device includes light sensitive sources that are separately able to deliver light with respect to a portion of a sample associated with the surface. The light source locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface. The imaging device and a distance of the portion of the sample to the light source locations are such that a useful image of the portion of the sample can be acquired directly by operation of the imaging device.
An imaging device can include both the light source locations and the light source locations and the light sensitive locations.-
公开(公告)号：US20200379234A1
公开(公告)日：2020-12-03
申请号：US16995271
申请日：2020-08-17
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay , Noah Hymes-Vandermeulen
Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
-
公开(公告)号：US20190242794A1
公开(公告)日：2019-08-08
申请号：US16367791
申请日：2019-03-28
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay
Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.
-
公开(公告)号：US20170075099A1
公开(公告)日：2017-03-16
申请号：US15360724
申请日：2016-11-23
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay , Noah Hymes-Vandermeulen
CPC classification number: G02B21/34 , G01N1/28 , G01N1/4077 , G01N15/0606 , G01N15/0612 , G01N15/1468 , G01N21/59 , G01N33/49 , G01N35/00029 , G01N2015/008 , G01N2015/1087 , G01N2015/1486
Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
Abstract translation: 除其他之外，第一表面被配置为接收样品并且用于显微镜装置。 存在相对于第一表面移动到预定位置的第二表面以形成位于第一表面和第二表面之间并且包含至少部分样品的样品空间。 存在被配置为将第二表面从初始位置移动到预定位置以形成样本空间的机构。 当样品在第一表面上就位时，第二表面的运动包括不仅仅是第二表面朝向第一表面的线性运动的轨迹。
-
Patent Agency Ranking
公开(公告)号：US20220206282A1
公开(公告)日：2022-06-30
申请号：US17696704
申请日：2022-03-16
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay , Noah Hymes-Vandermeulen
Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
-
公开(公告)号：US20190293524A9
公开(公告)日：2019-09-26
申请号：US15066065
申请日：2016-03-10
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay
Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.
-
公开(公告)号：US09989750B2
公开(公告)日：2018-06-05
申请号：US15360724
申请日：2016-11-23
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay , Noah Hymes-Vandermeulen
IPC: G02B21/34 , G01N21/59 , G01N1/40 , G01N1/28 , G01N15/14 , G01N33/49 , G01N35/00 , G01N15/00 , G01N15/06 , G01N15/10
CPC classification number: G02B21/34 , G01N1/28 , G01N1/4077 , G01N15/0606 , G01N15/0612 , G01N15/1468 , G01N21/59 , G01N33/49 , G01N35/00029 , G01N2015/008 , G01N2015/1087 , G01N2015/1486
Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
-
公开(公告)号：US20160187235A1
公开(公告)日：2016-06-30
申请号：US15066065
申请日：2016-03-10
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay
Abstract: Among other things, a diluted sample is generated based on mixing a small sample of blood with a one or more diluents. A thin film of the diluted sample is formed on the surface of a contact optical microscopy sensor. Red blood cells within a portion of the thin film of the diluted sample are illuminated using light of a predetermined wavelength. One or more images of the diluted sample are acquired based on illuminating the red blood cells within the portion of the thin film of the diluted sample. The acquired one or more images of the diluted sample are then processed. The mean corpuscular hemoglobin in the red blood cells within the portion of the thin film of the diluted sample is determined based on processing the acquired images of the diluted sample.
Abstract translation: 除此之外，基于将小样本的血液与一种或多种稀释剂混合而产生稀释的样品。 在接触式光学显微镜传感器的表面上形成稀薄样品的薄膜。 使用预定波长的光照射稀释样品的薄膜部分内的红细胞。 基于稀释样品的薄膜部分内的红细胞的照射，获得稀释样品的一个或多个图像。 然后处理所获得的稀释样品的一个或多个图像。 基于稀释样品的获取图像的处理，确定稀释样品薄膜部分内红细胞中的平均红细胞血红蛋白。
-
公开(公告)号：US11874452B2
公开(公告)日：2024-01-16
申请号：US17696704
申请日：2022-03-16
Applicant: Alentic Microscience Inc.
Inventor： Alan Marc Fine , Hershel Macaulay , Noah Hymes-Vandermeulen
IPC: G01N21/59 , G02B21/34 , G01N1/40 , G01N15/06 , G01N1/28 , G01N15/14 , G01N33/49 , G01N35/00 , G01N15/00 , G01N15/10
CPC classification number: G02B21/34 , G01N1/28 , G01N1/4077 , G01N15/0612 , G01N15/1468 , G01N21/59 , G01N33/49 , G01N15/0606 , G01N35/00029 , G01N2015/008 , G01N2015/1087 , G01N2015/1486
Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
-
-
-
-
-
-
-
-
-
Search Results
23
records
(took 0.018 seconds)
