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公开(公告)号：US11890555B2
公开(公告)日：2024-02-06
申请号：US18105429
申请日：2023-02-03
发明人： Brandon H. McNaughton , John G. Younger , Leo Ostruszka , Jonathan Roussey , Gene Parunak , Aaron Kehrer
CPC分类号： B01D21/0084 , B01D21/2433 , B01D21/262 , B01L3/5021 , B01L2200/026 , B01L2200/0652 , B01L2400/06 , G01N33/491
摘要： A method and system for buoyant separation of a target constituent of a sample, the method comprising: at a process chamber, combining a volume of substrates having a first density with the sample, thereby producing a population of target-bound complexes comprising the target constituent bound to at least a portion of the volume of substrates; within the process chamber, physically separating the population of target-bound complexes from the sample based upon interaction between the volume of substrates and an applied force; aggregating the population of target-bound complexes at a collection region of the process chamber; extracting the population of target-bound complexes from the process chamber; and processing the target constituent from the population of target-bound complexes for further analysis.
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公开(公告)号：US20200009614A1
公开(公告)日：2020-01-09
申请号：US16506865
申请日：2019-07-09
发明人： Brandon H. McNaughton , Nadia Petlakh , John G. Younger , Greg Hermanson , Bill Hyun , Vanessa Kelchner
摘要： A system for buoyant particle processing includes: a reaction vessel, a stirring mechanism, a set of one or more pumps, and a filter. The system can additionally or alternatively include a set of pathways and/or any other suitable component(s). A method for buoyant particle processing includes: stirring the contents of a reaction vessel; washing a set of buoyant particles; and filtering the contents of the reaction vessel. Additionally or alternatively, the method can include any or all of: preprocessing the set of buoyant particles; adding a set of inputs to the reaction vessel; washing the set of buoyant particles; repeating one or more; and/or any other suitable process(es).
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公开(公告)号：US12090514B2
公开(公告)日：2024-09-17
申请号：US18096769
申请日：2023-01-13
发明人： Brandon H. McNaughton , Nadia Petlakh , John G. Younger , Greg Hermanson , Bill Hyun , Vanessa Kelchner
IPC分类号： B05D7/00 , B05C3/02 , B05C11/10 , B05C19/02 , B05D1/18 , B05D1/22 , B05D1/36 , B05D5/04 , C12M1/00 , C12M1/26
CPC分类号： B05D7/5883 , B05C3/02 , B05C11/10 , B05C19/02 , B05D1/18 , B05D1/22 , B05D1/36 , B05D5/04 , C12M33/00 , C12M47/04
摘要： A system for buoyant particle processing includes: a reaction vessel, a stirring mechanism, a set of one or more pumps, and a filter. The system can additionally or alternatively include a set of pathways and/or any other suitable component(s). A method for buoyant particle processing includes: stirring the contents of a reaction vessel; washing a set of buoyant particles; and filtering the contents of the reaction vessel. Additionally or alternatively, the method can include any or all of: preprocessing the set of buoyant particles; adding a set of inputs to the reaction vessel; washing the set of buoyant particles; repeating one or more; and/or any other suitable process(es).
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公开(公告)号：US20230166291A1
公开(公告)日：2023-06-01
申请号：US18096769
申请日：2023-01-13
发明人： Brandon H. McNaughton , Nadia Petlakh , John G. Younger , Greg Hermanson , Bill Hyun , Vanessa Kelchner
摘要： A system for buoyant particle processing includes: a reaction vessel, a stirring mechanism, a set of one or more pumps, and a filter. The system can additionally or alternatively include a set of pathways and/or any other suitable component(s). A method for buoyant particle processing includes: stirring the contents of a reaction vessel; washing a set of buoyant particles; and filtering the contents of the reaction vessel. Additionally or alternatively, the method can include any or all of: preprocessing the set of buoyant particles; adding a set of inputs to the reaction vessel; washing the set of buoyant particles; repeating one or more; and/or any other suitable process(es).
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公开(公告)号：US20220176407A1
公开(公告)日：2022-06-09
申请号：US17679688
申请日：2022-02-24
发明人： Brandon H. McNaughton , Nadia Petlakh , John G. Younger , Greg Hermanson , Bill Hyun , Vanessa Kelchner
摘要： A system for buoyant particle processing includes: a reaction vessel, a stirring mechanism, a set of one or more pumps, and a filter. The system can additionally or alternatively include a set of pathways and/or any other suitable component(s). A method for buoyant particle processing includes: stirring the contents of a reaction vessel; washing a set of buoyant particles; and filtering the contents of the reaction vessel. Additionally or alternatively, the method can include any or all of: preprocessing the set of buoyant particles; adding a set of inputs to the reaction vessel; washing the set of buoyant particles; repeating one or more; and/or any other suitable process(es).
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公开(公告)号：US12102942B2
公开(公告)日：2024-10-01
申请号：US17671271
申请日：2022-02-14
发明人： Brandon H. McNaughton , John G. Younger , Leo Ostruszka , Jonathan Roussey , Gene Parunak , Aaron Kehrer
CPC分类号： B01D21/0084 , B01D21/2433 , B01D21/262 , B01L3/5021 , B01L2200/026 , B01L2200/0652 , B01L2400/06 , G01N33/491
摘要： A method and system for buoyant separation of a target constituent of a sample, the method comprising: at a process chamber, combining a volume of substrates having a first density with the sample, thereby producing a population of target-bound complexes comprising the target constituent bound to at least a portion of the volume of substrates; within the process chamber, physically separating the population of target-bound complexes from the sample based upon interaction between the volume of substrates and an applied force; aggregating the population of target-bound complexes at a collection region of the process chamber; extracting the population of target-bound complexes from the process chamber; and processing the target constituent from the population of target-bound complexes for further analysis.
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公开(公告)号：US20220161158A1
公开(公告)日：2022-05-26
申请号：US17671271
申请日：2022-02-14
发明人： Brandon H. McNaughton , John G. Younger , Leo Ostruszka , Jonathan Roussey , Gene Parunak , Aaron Kehrer
摘要： A method and system for buoyant separation of a target constituent of a sample, the method comprising: at a process chamber, combining a volume of substrates having a first density with the sample, thereby producing a population of target-bound complexes comprising the target constituent bound to at least a portion of the volume of substrates; within the process chamber, physically separating the population of target-bound complexes from the sample based upon interaction between the volume of substrates and an applied force; aggregating the population of target-bound complexes at a collection region of the process chamber; extracting the population of target-bound complexes from the process chamber; and processing the target constituent from the population of target-bound complexes for further analysis.
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公开(公告)号：US20180290077A1
公开(公告)日：2018-10-11
申请号：US16004874
申请日：2018-06-11
发明人： Brandon H. McNaughton , John G. Younger , Leo Ostruszka , Jonathan Roussey , Gene Parunak , Aaron Kehrer
摘要： A method and system for buoyant separation of a target constituent of a sample, the method comprising: at a process chamber, combining a volume of substrates having a first density with the sample, thereby producing a population of target-bound complexes comprising the target constituent bound to at least a portion of the volume of substrates; within the process chamber, physically separating the population of target-bound complexes from the sample based upon interaction between the volume of substrates and an applied force; aggregating the population of target-bound complexes at a collection region of the process chamber; extracting the population of target-bound complexes from the process chamber; and processing the target constituent from the population of target-bound complexes for further analysis.
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公开(公告)号：US20230182043A1
公开(公告)日：2023-06-15
申请号：US18105429
申请日：2023-02-03
发明人： Brandon H. McNaughton , John G. Younger , Leo Ostruszka , Jonathan Roussey , Gene Parunak , Aaron Kehrer
CPC分类号： B01D21/0084 , B01L3/5021 , B01D21/262 , B01D21/2433 , G01N33/491
摘要： A method and system for buoyant separation of a target constituent of a sample, the method comprising: at a process chamber, combining a volume of substrates having a first density with the sample, thereby producing a population of target-bound complexes comprising the target constituent bound to at least a portion of the volume of substrates; within the process chamber, physically separating the population of target-bound complexes from the sample based upon interaction between the volume of substrates and an applied force; aggregating the population of target-bound complexes at a collection region of the process chamber; extracting the population of target-bound complexes from the process chamber; and processing the target constituent from the population of target-bound complexes for further analysis.
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公开(公告)号：US11583893B2
公开(公告)日：2023-02-21
申请号：US17679688
申请日：2022-02-24
发明人： Brandon H. McNaughton , Nadia Petlakh , John G. Younger , Greg Hermanson , Bill Hyun , Vanessa Kelchner
摘要： A system for buoyant particle processing includes: a reaction vessel, a stirring mechanism, a set of one or more pumps, and a filter. The system can additionally or alternatively include a set of pathways and/or any other suitable component(s). A method for buoyant particle processing includes: stirring the contents of a reaction vessel; washing a set of buoyant particles; and filtering the contents of the reaction vessel. Additionally or alternatively, the method can include any or all of: preprocessing the set of buoyant particles; adding a set of inputs to the reaction vessel; washing the set of buoyant particles; repeating one or more; and/or any other suitable process(es).
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