公开(公告)号：US20170114381A1

公开(公告)日：2017-04-27

申请号：US15316147

申请日：2015-06-04

Applicant: AMGEN INC.

Inventor： Chetan GOUDAR ,  Sean COLE ,  Nicole LE ,  Henry LIN ,  Jonathan LULL ,  Tharmala THARMALINGAM

IPC: C12P21/00 ,  C12M1/26 ,  C07K16/00 ,  C12M1/00

CPC classification number: C12P21/00 ,  C07K16/00 ,  C07K2317/14 ,  C12M29/04 ,  C12M29/10 ,  C12M29/16 ,  C12M33/14 ,  C12N5/0018 ,  C12N2510/02 ,  C12N2511/00

Abstract: The invention provides methods and materials for culturing mammalian cells and harvesting recombinant protein.

公开(公告)号：US20220356502A1

公开(公告)日：2022-11-10

申请号：US17746008

申请日：2022-05-17

Applicant: Amgen Inc.

Inventor： Chetan GOUDAR ,  Sean COLE ,  Nicole SABO ,  Henry LIN ,  Jonathan LULL ,  Tharmala THARMALINGAM

IPC: C12P21/00 ,  C12M1/00 ,  C12N5/00 ,  C12M1/36 ,  C07K16/00 ,  C12M1/26

Abstract: The invention provides methods and materials for culturing mammalian cells and harvesting recombinant protein.

公开(公告)号：US20220136025A1

公开(公告)日：2022-05-05

申请号：US17537766

申请日：2021-11-30

Applicant: Amgen Inc.

Inventor： Chetan GOUDAR ,  Sean COLE ,  Nicole SABO ,  Henry LIN ,  Jonathan LULL ,  Tharmala THARMALINGAM

IPC: C12P21/00 ,  C12M1/00 ,  C07K16/00 ,  C12M1/26 ,  C12N5/00 ,  C12M1/36

Abstract: The invention provides methods and materials for culturing mammalian cells and harvesting recombinant protein.

公开(公告)号：US20160040207A1

公开(公告)日：2016-02-11

申请号：US14821574

申请日：2015-08-07

Applicant: AMGEN INC.

Inventor： Matthew I. JERUMS ,  Amanda KANO ,  Henry LIN ,  Shun LUO ,  Jian WU ,  Rebecca E. McCOY ,  Arvia E. MORRIS

IPC: C12P21/00

CPC classification number: C12P21/00 ,  C12N5/0037 ,  C12N5/0043 ,  C12N2500/32 ,  C12N2510/02 ,  C12N2511/00

Abstract: The present invention relates to methods for mammalian cell culture. The methods make use of independent tyrosine and cystine feed streams.

Abstract translation: 本发明涉及哺乳动物细胞培养的方法。 该方法利用独立的酪氨酸和胱氨酸进料流。