公开(公告)号：US20220218869A1

公开(公告)日：2022-07-14

申请号：US17608032

申请日：2020-04-28

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Robert A. ASMUS ,  Patrick J. PARKS ,  Shrijana B. SHRESTHA

IPC: A61L26/00

Abstract: A composition for treating wounds is provided. The composition includes an antimicrobial component, an emulsifying agent, and a cidatrope component. The antimicrobial component can be selected from octenidine, poly(hexamethylene biguanide), a quaternary ammonium antimicrobial compound, and salts thereof. The cidatrope is not an alpha-hydroxy acid, a beta-hydroxy acid, a chelating agent, a (C1-C4)alkyl carboxylic acid, a (C6-C12)aryl carboxylic acid, a (C6-C12)aralkyl carboxylic acid, a (C6-C12)alkalyl carboxylic acid, a phenolic compound, a (C1-C10)monohydric alkyl alcohol, or an ether glycol. In certain embodiments, the composition can be substantially free of water and C2-C5 lower alcohols. In certain embodiments, the composition further can comprise water. Methods of using the composition are also provided.

公开(公告)号：US20220298389A1

公开(公告)日：2022-09-22

申请号：US17612375

申请日：2020-05-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Ying ZHANG ,  Robert A. ASMUS ,  Zhicheng TIAN ,  Kheng VANG ,  James DIZIO ,  Patrick J. PARKS ,  Brian E. SPIEWAK

IPC: C09J7/38 ,  A61L15/58 ,  A61L24/04

Abstract: Adhesive compositions are disclosed that include an octenidine salt, a resin system, a plasticizer, and a cidatrope. The dried adhesive compositions are substantially free of water and C2-C5 alcohols. The adhesive compositions disclosed are formulations that provide rapid and persistent antimicrobial activity and may be useful, for example, in wound dressings, surgical drapes, and medical tapes.

公开(公告)号：US20220105018A1

公开(公告)日：2022-04-07

申请号：US17600010

申请日：2020-03-26

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Ying ZHANG ,  Robert A. ASMUS ,  Zhicheng TIAN ,  Kheng VANG ,  James P. DIZIO ,  Patrick J. PARKS ,  Brian E. SPIEWAK

IPC: A61K8/49 ,  A61K8/37 ,  A61K8/34 ,  A61Q17/00

Abstract: Antimicrobial compositions containing an antimicrobial agent, such as an octenidine salt, a solubilizer, such as a glycol, and a cidatrope, such as a C8-C26 alcohol, an ether, an amide, an ester, and combinations thereof, where the compositions are substantially free of water and C2-C5 alcohols and methods of making such antimicrobial compositions.

公开(公告)号：US20200030486A1

公开(公告)日：2020-01-30

申请号：US16338140

申请日：2017-10-03

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jonathan J. O'HARE ,  Mikhail L. PEKUROVSKY ,  Amy S. DETERMAN ,  Gino L. PITERA ,  Jason W. BJORK ,  Daniel V. NORTON ,  Robert A. ASMUS

IPC: A61L26/00 ,  B29C43/24

Abstract: A method of forming a fibrin hydrogel composition including providing one or more unitary masses of a fibrin hydrogel, dividing at least one of the unitary masses of the fibrin hydrogel into a multiplicity of smaller pieces of the fibrin hydrogel, and recombining at least a portion of the smaller pieces into a cohesive mass. Dividing at least one of the unitary masses of fibrin hydrogel into a multiplicity of smaller pieces may include shearing or cutting the unitary masses to form an aqueous dispersion of the fibrin hydrogel in an aqueous medium. The aqueous dispersion of fibrin hydrogel may be applied to a substrate on a roller or an endless belt, and is optionally overlaid by a scrim. The cohesive mass of fibrin hydrogel, which may be formed by removing at least a portion of the aqueous medium from the aqueous dispersion of the smaller pieces of the fibrin hydrogel, finds uses in wound dressing articles.