公开(公告)号：US08741227B2

公开(公告)日：2014-06-03

申请号：US12693969

申请日：2010-01-26

申请人： Yasuhiko Yokoi ,  Jiro Ohnishi ,  Shinji Fukui ,  Akifumi Iwama

发明人： Yasuhiko Yokoi ,  Jiro Ohnishi ,  Shinji Fukui ,  Akifumi Iwama

IPC分类号： A61L2/00 ,  A61L9/00 ,  B01L1/04 ,  B01D47/00 ,  A61L2/02 ,  A61L2/20 ,  A61L2/22 ,  A61L9/015 ,  F24F13/28 ,  B01D45/00

CPC分类号： A61L9/00 ,  A61L2/0017 ,  A61L2/022 ,  A61L2/208 ,  A61L2/22 ,  A61L2/24 ,  A61L9/015 ,  A61L2202/122 ,  A61L2202/14 ,  B01D45/00 ,  C12M37/00 ,  F24F13/28

摘要： An isolator includes a workroom having a first sterilizing material supply port, a first sterilizing material discharge port, a first gas supply port and a first gas discharge port, a sterilization chamber having a second sterilizing material supply port, a second sterilizing material discharge port, a second gas supply port and a second gas discharge port, a sterilizing material supply unit, a first sterilizing material supply path connecting the sterilizing material supply unit to the first sterilizing material supply port, a second sterilizing material supply path connecting the sterilizing material supply unit to the second sterilizing material supply port, a first circulating path connecting the first sterilizing material discharge port to the sterilizing material supply unit, a second circulating path connecting the second sterilizing material discharge port to the sterilizing material supply unit, a first gas supply path, a second gas supply path, a first gas discharge path, a second gas discharge path, and a control unit.

摘要翻译： 隔离器包括具有第一灭菌材料供给口，第一灭菌材料排出口，第一气体供给口和第一排气口的工作室，具有第二灭菌材料供给口的灭菌室，第二灭菌材料排出口， 第二供气口和第二气体排出口，灭菌材料供给单元，将灭菌材料供给单元连接到第一灭菌材料供给口的第一灭菌材料供给路径，连接灭菌材料供给单元的第二灭菌材料供给路径 第二消毒材料供给口，将第一消毒材料排出口与灭菌材料供给单元连接的第一循环路径，将第二消毒材料排出口与灭菌材料供给单元连接的第二循环路径，第一供气路径， 第二气体供给路径，第一气体排出路径 离子气体排出路径和控制单元。

公开(公告)号：US20120273047A1

公开(公告)日：2012-11-01

申请号：US13457675

申请日：2012-04-27

申请人： Yasuhiko Yokoi ,  Koichi Kobayashi ,  Hiroshi Yamamoto ,  Hiroki Busujima

发明人： Yasuhiko Yokoi ,  Koichi Kobayashi ,  Hiroshi Yamamoto ,  Hiroki Busujima

IPC分类号： F17D3/00 ,  C12M1/00

CPC分类号： C12M23/44 ,  A61L2/208 ,  B01L1/025 ,  C12M41/14 ,  Y10T137/0318

摘要： An isolator capable of having a culture apparatus demountably mounted thereto, the isolator includes: a working chamber; a storage chamber; a first opening configured to allow a culture chamber of the culture apparatus and the working chamber to communicate with each other, when the culture apparatus has been mounted; a second opening configured to allow the working chamber and the storage chamber to communicate with each other; a first door configured to close the second opening so as to hermetically seal the storage chamber; and a temperature adjusting device configured to, when culture taken out of the culture chamber has been stored in the storage chamber, and the storage chamber has been hermetically sealed, and thereafter the culture apparatus has been demounted, adjust temperature of the culture stored in the storage chamber.

摘要翻译： 一种能够具有可拆卸地安装在其上的培养装置的隔离器，所述隔离器包括：工作室; 储存室; 当培养装置已被安装时，构造成允许培养装置的培养室和工作室相互连通的第一开口; 第二开口，其构造成允许所述工作室和所述储存室彼此连通; 第一门，其构造成关闭所述第二开口以密封所述储存室; 以及温度调节装置，其被配置为当从所述培养室取出的培养物已被储存在所述储存室中并且所述储存室已被气密密封时，并且其后所述培养装置已经被拆除，则调节所述培养室中储存的培养物的温度 储存室。

公开(公告)号：US20110212513A1

公开(公告)日：2011-09-01

申请号：US13035538

申请日：2011-02-25

申请人： Yasuhiko YOKOI ,  Akifumi Iwama ,  Shinji Fukui ,  Atsushi Nakao ,  Hiroshi Yamamoto ,  Jirou Ohnishi ,  Hironobu Sunayama ,  Kanjun Yamamoto

发明人： Yasuhiko YOKOI ,  Akifumi Iwama ,  Shinji Fukui ,  Atsushi Nakao ,  Hiroshi Yamamoto ,  Jirou Ohnishi ,  Hironobu Sunayama ,  Kanjun Yamamoto

IPC分类号： C12M1/04

CPC分类号： C12M37/04 ,  C12M37/00 ,  C12M41/14 ,  Y10S435/809

摘要： An isolator for cultivating cells including a working chamber having a plurality of gloves arranged side by side into which operator's hands are inserted to operate cells, the working chamber being sectioned into at least an operation area for operating the cells, and an auxiliary working area for opening a packaged auxiliary instrument used to operate the cells, a gas supply unit that supplies gas into the working chamber so that the gas flows downwardly from an upper side in the working chamber, and a gas flow control unit for controlling the flow of the downwardly flowing gas so that the gas flows from the operation area to the auxiliary working area around the gloves, wherein the gas flow control unit has an exhaust hole portion that has an opened area for passing the gas therethrough and is provided at a lower portion of at least the auxiliary working area, and through which the gas in the auxiliary working area is exhausted.

摘要翻译： 一种用于培养细胞的隔离器，包括具有并排设置的多个手套的工作室，操作者的手被插入操作单元中，所述工作室被分成至少一个用于操作所述单元的操作区域，以及辅助工作区域 打开用于操作细胞的包装的辅助仪器，气体供应单元，其将气体供应到工作室中，使得气体从工作室中的上侧向下流动;气体流量控制单元，用于控制向下的流动 流动气体，使得气体从操作区域流到手套周围的辅助工作区域，其中气体流量控制单元具有排气孔部分，该排气孔部分具有用于使气体通过的开口区域，并且设置在下部 至少辅助工作区域，辅助工作区域中的气体通过其排出。

公开(公告)号：US07923242B2

公开(公告)日：2011-04-12

申请号：US11346564

申请日：2006-02-03

申请人： Eiji Kono ,  Hironobu Sekine ,  Yasuhiko Yokoi ,  Akihumi Iwama

发明人： Eiji Kono ,  Hironobu Sekine ,  Yasuhiko Yokoi ,  Akihumi Iwama

IPC分类号： C12M1/34 ,  C12M3/00

CPC分类号： C12Q1/04 ,  G01N21/0317 ,  G01N21/75 ,  G01N21/78 ,  G01N2021/7783

摘要： The objective of the present invention is to provide a simple microorganism detection apparatus that reduces detection time and that provides improved detection sensitivity, especially for gram-negative bacteria. The microorganism detection apparatus of the present invention includes: a detection target introduction portion, into which a sample and reagents are to be introduced; a detector, for detecting the color tone of the reagent introduced into the detection target introduction portion; a sample holder, for holding the sample to be introduced into the detection target introduction portion; a culture solution holder, for holding a culture solution used for microorganism culturing; and reagent holders, for holding the reagents to be introduced into the detection target introduction portion, wherein the presence/absence of microorganisms in the sample is determined based on the detected color tone.

摘要翻译： 本发明的目的是提供一种简单的微生物检测装置，其减少检测时间并且提供改善的检测灵敏度，特别是革兰氏阴性细菌。 本发明的微生物检测装置包括：检测对象物导入部，将样品和试剂引入其中的检测对象物导入部; 检测器，用于检测引入到检测目标导入部分中的试剂的色调; 样品保持器，用于保持待引入检测对象物导入部的样品; 用于保持用于微生物培养的培养液的培养液保持器; 和试剂保持器，用于保持要引入到检测对象物导入部分中的试剂，其中基于检测到的色调确定样品中存在/不存在微生物。

公开(公告)号：US20060246578A1

公开(公告)日：2006-11-02

申请号：US11346564

申请日：2006-02-03

申请人： Eiji Kono ,  Hironobu Sekine ,  Yasuhiko Yokoi ,  Akihumi Iwama

发明人： Eiji Kono ,  Hironobu Sekine ,  Yasuhiko Yokoi ,  Akihumi Iwama

IPC分类号： C12M1/34

CPC分类号： C12Q1/04 ,  G01N21/0317 ,  G01N21/75 ,  G01N21/78 ,  G01N2021/7783

摘要： The objective of the present invention is to provide a simple microorganism detection apparatus that reduces detection time and that provides improved detection sensitivity, especially for gram-negative bacteria. The microorganism detection apparatus of the present invention includes: a detection target introduction portion, into which a sample and reagents are to be introduced; a detector, for detecting the color tone of the reagent introduced into the detection target introduction portion; a sample holder, for holding the sample to be introduced into the detection target introduction portion; a culture solution holder, for holding a culture solution used for microorganism culturing; and reagent holders, for holding the reagents to be introduced into the detection target introduction portion, wherein the presence/absence of microorganisms in the sample is determined based on the detected color tone.

摘要翻译： 本发明的目的是提供一种简单的微生物检测装置，其减少检测时间并且提供改善的检测灵敏度，特别是革兰氏阴性细菌。 本发明的微生物检测装置包括：检测对象物导入部，将样品和试剂引入其中的检测对象物导入部; 检测器，用于检测引入到检测目标导入部分中的试剂的色调; 样品保持器，用于保持待引入检测对象物导入部的样品; 用于保持用于微生物培养的培养液的培养液保持器; 和试剂保持器，用于保持待引入到检测对象物导入部分中的试剂，其中基于检测到的色调确定样品中存在/不存在微生物。

公开(公告)号：US06826932B2

公开(公告)日：2004-12-07

申请号：US10241779

申请日：2002-09-12

申请人： Yasuaki Sonoda ,  Hiroshi Yamamoto ,  Yasuhiko Yokoi ,  Takao Kinouchi

发明人： Yasuaki Sonoda ,  Hiroshi Yamamoto ,  Yasuhiko Yokoi ,  Takao Kinouchi

IPC分类号： D06F3722

CPC分类号： D06F37/225

摘要： A washing machine 10 of the drum type comprises a drum 20 rotatable about a horizontal or inclined center of rotation, a drive motor 50 for rotating the drum, liquid holding chambers 36 for holding a liquid therein centrifugally, means for detecting an eccentric load of laundry in the drum, and control means 72 for adjusting the amounts of liquid in the chambers in accordance with the detected eccentric load. The amounts of liquid in the chambers are adjustable by braking the drum in rotation. The machine has moment of inertia measuring means 60 for detecting the rotation of the drum. The control means calculates the moment of inertia acting on the drum based on the rotation of the drum detected by the moment of inertia measuring means, and adjusts the magnitude of braking force to be applied to the drum in accordance with the calculated moment of inertia so as to decelerate the drum at a constant rate in adjusting the amounts of liquid in the chambers.

摘要翻译： 滚筒式洗衣机10包括可围绕水平或倾斜旋转中心旋转的滚筒20，用于旋转滚筒的驱动马达50，用于将离心机中保持液体的液体保持室36用于检测衣物的偏心负荷 以及控制装置72，用于根据检测到的偏心负载来调节室内的液体量。 室内的液体量可通过旋转制动鼓来调节。 机器具有用于检测滚筒旋转的惯性测量装置60。 控制装置根据由转动惯量测量装置检测到的滚筒旋转来计算作用在滚筒上的转动惯量，并根据计算出的转动惯量来调整施加于滚筒的制动力的大小，因此 以便在调节室中的液体量时以恒定速率使滚筒减速。

公开(公告)号：US08765064B2

公开(公告)日：2014-07-01

申请号：US12731708

申请日：2010-03-25

申请人： Yasuhiko Yokoi ,  Jiro Ohnishi ,  Shinji Fukui ,  Akifumi Iwama ,  Hiroshi Yamamoto ,  Masaki Harada ,  Tatsuya Hirose

发明人： Yasuhiko Yokoi ,  Jiro Ohnishi ,  Shinji Fukui ,  Akifumi Iwama ,  Hiroshi Yamamoto ,  Masaki Harada ,  Tatsuya Hirose

IPC分类号： B06B1/00 ,  A61L2/00 ,  A61L9/00 ,  B01J7/00

CPC分类号： A61L2/208 ,  A61L2/22 ,  A61L2/26 ,  A61L2202/11

摘要： A sterile-substance-supplying apparatus comprising: an atomization unit including a reservoir unit to reserve hydrogen peroxide, and an ultrasound vibrator to impart ultrasound vibration to the reserved hydrogen peroxide to be atomized; an evaporation unit, provided above the reservoir unit, that heats the atomized hydrogen peroxide to be evaporated; a connecting member connecting the evaporation unit and the atomization unit to each other; a hydrogen-peroxide-supply port to allow the hydrogen peroxide to be supplied to the reservoir unit; a carrier-gas-supply port, provided at the connecting member, that allows carrier gas for allowing the atomized hydrogen peroxide to flow to the evaporation unit to be supplied; and a container portion to reserve a substance for transmitting the ultrasound vibration generated by the ultrasound vibrator, and a metal vibrating plate, provided at a bottom portion of the reservoir unit, that transmits to the hydrogen peroxide the ultrasound vibration transmitted through the substance.

摘要翻译： 1.一种无菌物质供给装置，其特征在于，包括：雾化单元，其具有储存单元以保留过氧化氢;以及超声波振动器，用于对预定的要被雾化的过氧化氢赋予超声波振动; 设置在储存器单元上方的蒸发单元，其加热待蒸发的雾化过氧化氢; 将蒸发单元和雾化单元彼此连接的连接构件; 一个过氧化氢供应口，以允许过氧化氢被供应到贮存器单元; 设置在所述连接构件上的载气供给口，其允许载气使所述雾化过氧化氢流入所述蒸发单元供给; 以及容纳部，其保留用于传输由超声波振动器产生的超声波振动的物质;以及金属振动板，其设置在所述储存器单元的底部，所述金属振动板向所述过氧化氢传递通过所述物质传播的超声波振动。

公开(公告)号：US08753877B2

公开(公告)日：2014-06-17

申请号：US13021352

申请日：2011-02-04

申请人： Shinji Fukui ,  Yasuhiko Yokoi ,  Akifumi Iwama ,  Hiroshi Yamamoto ,  Jirou Ohnishi

发明人： Shinji Fukui ,  Yasuhiko Yokoi ,  Akifumi Iwama ,  Hiroshi Yamamoto ,  Jirou Ohnishi

IPC分类号： C12M1/00 ,  C12M3/00 ,  B01L7/00

CPC分类号： C12M23/48 ,  B01L7/52 ,  C12M29/04 ,  C12M37/02 ,  C12M41/14

摘要： An incubator including a cultivating chamber for cultivating cultures, a water supply control unit for supplying water into the cultivating chamber through a water supply passage and adjusting the humidity of the inside of the cultivating chamber, and a filter provided in the water supply passage.

摘要翻译： 一种培养箱，包括用于培养培养物的栽培室，一个供水控制单元，用于通过供水通道向培养室供水并调节培养室内部的湿度，以及设置在供水通道中的过滤器。

公开(公告)号：US08721983B2

公开(公告)日：2014-05-13

申请号：US12748663

申请日：2010-03-29

申请人： Yasuhiko Yokoi ,  Hiroshi Yamamoto ,  Atsushi Nakao ,  Jiro Ohnishi ,  Shinji Fukui ,  Akifumi Iwama ,  Masaki Harada ,  Yoshiaki Sugimura ,  Katsuya Hirai

发明人： Yasuhiko Yokoi ,  Hiroshi Yamamoto ,  Atsushi Nakao ,  Jiro Ohnishi ,  Shinji Fukui ,  Akifumi Iwama ,  Masaki Harada ,  Yoshiaki Sugimura ,  Katsuya Hirai

IPC分类号： A61L2/20

CPC分类号： A61L2/208 ,  A61L2202/11 ,  A61L2202/15 ,  C12M37/00

摘要： A sterilizer is connectable to an external chamber. A sterilization gas generator is configured to generate sterilization gas. A gas supply system including a first gas supply system which is configured to supply the sterilization gas from the sterilization gas generator to a sterilization chamber; and a second gas supply system which is different from the first gas supply system and configured to supply the sterilization gas from the sterilization gas generator to the external chamber.

摘要翻译： 灭菌器可连接到外部室。 杀菌气体发生器构造成产生灭菌气体。 一种气体供给系统，包括：第一气体供给系统，其被构造成将灭菌气体从所述灭菌气体发生器供给到灭菌室; 以及第二气体供给系统，其与第一气体供给系统不同，并且构造成将灭菌气体从灭菌气体发生器供给到外部室。

公开(公告)号：US20130336844A1

公开(公告)日：2013-12-19

申请号：US13971326

申请日：2013-08-20

申请人： Yasuhiko Yokoi ,  Koichi Kobayashi ,  Hiroshi Yamamoto

发明人： Yasuhiko Yokoi ,  Koichi Kobayashi ,  Hiroshi Yamamoto

IPC分类号： B01J19/00

CPC分类号： B01J19/00 ,  A61L2/208 ,  A61L9/14 ,  A61L2202/122 ,  A61L2202/13 ,  A61L2209/14 ,  A61L2209/16 ,  C12M37/00

摘要： An isolator includes: a contamination-target chamber including an inlet and outlet having intake and discharge filters, respectively; and a decontaminating-gas-supply unit to supply decontaminating gas into the chamber without flowing through the filters, the unit including: an atomizer including first and second ports and a nozzle; a first pipe having one and the other ends connected to a compressor and the first port, respectively; a second pipe having one end connected to the second port and the other end open; a reservoir; a pump to take in decontamination solution from the reservoir; and a third pipe, having one end connected to the pump, thorough which the solution flows, the atomizer configured to, when injecting from the nozzle intake air from the first port, suction the solution, via the second pipe, by negative pressure produced in the second port; and inject the solution in an atomized state, mixing it with air.

摘要翻译： 隔离器包括：污染目标室，分别包括具有进气和排气过滤器的入口和出口; 以及净化气体供给单元，其在不流过所述过滤器的情况下向所述室内供给净化气体，所述单元包括：雾化器，其包括第一和第二端口和喷嘴; 第一管，其一端和另一端分别连接到压缩机和第一端口; 第二管，其一端连接到第二端口，另一端打开; 一个水库 从水库取出去污溶液的泵; 以及第三管，其一端连接到所述泵，所述溶液流动，所述雾化器构造成当从所述喷嘴吸入空气从所述第一端口喷射时，经由所述第二管经由所述第二管吸入所述溶液， 第二个港口 并将溶液注入雾化状态，将其与空气混合。