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公开(公告)号：US07824898B2
公开(公告)日：2010-11-02
申请号：US10917179
申请日：2004-08-11
申请人： S. Christopher Davis , Richard John Fox , Gjalt W. Huisman , Vesna Gavrilovic , Lisa Marie Newman
发明人： S. Christopher Davis , Richard John Fox , Gjalt W. Huisman , Vesna Gavrilovic , Lisa Marie Newman
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
摘要翻译： 本发明涉及新型卤代醇脱卤素酶多肽和编码它们的多核苷酸。 这些多肽可用于制备4-取代-3-丁酸衍生物和连位氰基羟基取代的羧酸酯。 本发明还提供相关载体，宿主细胞和方法。
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公开(公告)号：US20050153417A1
公开(公告)日：2005-07-14
申请号：US10917179
申请日：2004-08-11
申请人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Lisa Newman
发明人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Lisa Newman
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
摘要翻译： 本发明涉及新型卤代醇脱卤素酶多肽和编码它们的多核苷酸。 这些多肽可用于制备4-取代-3-丁酸衍生物和连位氰基羟基取代的羧酸酯。 本发明还提供相关载体，宿主细胞和方法。
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公开(公告)号：US08252554B2
公开(公告)日：2012-08-28
申请号：US12505374
申请日：2009-07-17
申请人： S. Christopher Davis , Lisa Marie Newman , Vesna Gavrilovic , Gjalt W. Huisman , Richard John Fox , Emily C. Mundorff
发明人： S. Christopher Davis , Lisa Marie Newman , Vesna Gavrilovic , Gjalt W. Huisman , Richard John Fox , Emily C. Mundorff
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
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公开(公告)号：US20090298125A1
公开(公告)日：2009-12-03
申请号：US12505374
申请日：2009-07-17
申请人： S. Christopher Davis , Richard J. Fox , Gjalt W. Huisman , Vesna Gavrilovic , Emily C. Mundorff , Lisa M. Newman
发明人： S. Christopher Davis , Richard J. Fox , Gjalt W. Huisman , Vesna Gavrilovic , Emily C. Mundorff , Lisa M. Newman
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
摘要翻译： 本发明涉及新型卤代醇脱卤素酶多肽和编码它们的多核苷酸。 这些多肽可用于制备4-取代-3-丁酸衍生物和连位氰基羟基取代的羧酸酯。 本发明还提供相关载体，宿主细胞和方法。
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公开(公告)号：US20050272064A1
公开(公告)日：2005-12-08
申请号：US11067323
申请日：2005-02-23
申请人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Lisa Newman
发明人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Lisa Newman
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
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公开(公告)号：US07588928B2
公开(公告)日：2009-09-15
申请号：US11266747
申请日：2005-11-02
申请人： S. Christopher Davis , Richard John Fox , Gjalt W. Huisman , Vesna Gavrilovic , Emily C. Mundorff , Lisa Marie Newman
发明人： S. Christopher Davis , Richard John Fox , Gjalt W. Huisman , Vesna Gavrilovic , Emily C. Mundorff , Lisa Marie Newman
IPC分类号： C12N9/88
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
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公开(公告)号：US07541171B2
公开(公告)日：2009-06-02
申请号：US11067323
申请日：2005-02-23
申请人： S. Christopher Davis , Richard John Fox , Gjalt W. Huisman , Vesna Gavrilovic , Lisa Marie Newman
发明人： S. Christopher Davis , Richard John Fox , Gjalt W. Huisman , Vesna Gavrilovic , Lisa Marie Newman
IPC分类号： C12N9/88
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
摘要翻译： 本发明涉及新型卤代醇脱卤素酶多肽和编码它们的多核苷酸。 这些多肽可用于制备4-取代-3-丁酸衍生物和连位氰基羟基取代的羧酸酯。 本发明还提供相关载体，宿主细胞和方法。
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公开(公告)号：US20060099700A1
公开(公告)日：2006-05-11
申请号：US11266747
申请日：2005-11-02
申请人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Emily Mundorff , Lisa Newman
发明人： S. Davis , Richard Fox , Gjalt Huisman , Vesna Gavrilovic , Emily Mundorff , Lisa Newman
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
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公开(公告)号：US20120208259A1
公开(公告)日：2012-08-16
申请号：US13349514
申请日：2012-01-12
申请人： S. Christopher Davis , Richard John Fox , Gjalt W. Huisman , Vesna Gavrilovic , Lisa Marie Newman
发明人： S. Christopher Davis , Richard John Fox , Gjalt W. Huisman , Vesna Gavrilovic , Lisa Marie Newman
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
摘要翻译： 本发明涉及新型卤代醇脱卤素酶多肽和编码它们的多核苷酸。 这些多肽可用于制备4-取代-3-丁酸衍生物和连位氰基羟基取代的羧酸酯。 本发明还提供相关载体，宿主细胞和方法。
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公开(公告)号：US08101395B2
公开(公告)日：2012-01-24
申请号：US12573824
申请日：2009-10-05
申请人： S. Christopher Davis , Richard J. Fox , Gjalt W. Huisman , Vesna Gavrilovic , Lisa Marie Newman
发明人： S. Christopher Davis , Richard J. Fox , Gjalt W. Huisman , Vesna Gavrilovic , Lisa Marie Newman
摘要： The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
摘要翻译： 本发明涉及新型卤代醇脱卤素酶多肽和编码它们的多核苷酸。 这些多肽可用于制备4-取代-3-丁酸衍生物和连位氰基羟基取代的羧酸酯。 本发明还提供相关载体，宿主细胞和方法。
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