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公开(公告)号:US20140073019A1
公开(公告)日:2014-03-13
申请号:US14003386
申请日:2012-03-07
申请人: Nick Johannes Petrus Werckx , Tom Daniel Elink Schuurman , Sipko Maarten Kuijper , Harald Johan Ruijssenaars
发明人: Nick Johannes Petrus Werckx , Tom Daniel Elink Schuurman , Sipko Maarten Kuijper , Harald Johan Ruijssenaars
IPC分类号: C12P17/04
CPC分类号: C12P17/04 , C07K14/195 , C12N9/0004 , C12N9/0008 , C12Y102/01
摘要: The present invention relates to the field of biotransformation of furanic compounds. More particular the present invention relates to novel genetically modified cells with improved characteristics for biocatalytic transformation of furanic compounds and a vector suitable for the genetic modification of a host cell. Further aspects of the invention are aimed at processes for biotransformation of 5-(hydroxymethyl)furan-2-carboxylic acid (HMF-acid) and its precursors with the use of the cell according to the invention.
摘要翻译: 本发明涉及呋喃化合物的生物转化领域。 更具体地,本发明涉及具有改进的呋喃化合物的生物催化转化特性和适用于宿主细胞的遗传修饰的载体的新型遗传修饰细胞。 本发明的其它方面的目的在于使用本发明的细胞生物转化5-(羟甲基)呋喃-2-羧酸(HMF-酸)及其前体的方法。
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公开(公告)号:US09309546B2
公开(公告)日:2016-04-12
申请号:US14003386
申请日:2012-03-07
申请人: Nick Johannes Petrus Wierckx , Tom Daniel Elink Schuurman , Sipko Maarten Kuijper , Harald Johan Ruijssenaars
发明人: Nick Johannes Petrus Wierckx , Tom Daniel Elink Schuurman , Sipko Maarten Kuijper , Harald Johan Ruijssenaars
IPC分类号: C07K14/195 , C12P17/04 , C12N9/02
CPC分类号: C12P17/04 , C07K14/195 , C12N9/0004 , C12N9/0008 , C12Y102/01
摘要: The present invention relates to the field of biotransformation of furanic compounds. More particular the present invention relates to novel genetically modified cells with improved characteristics for biocatalytic transformation of furanic compounds and a vector suitable for the genetic modification of a host cell. Further aspects of the invention are aimed at processes for biotransformation of 5-(hydroxymethyl)furan-2-carboxylic acid (HMF-acid) and its precursors with the use of the cell according to the invention.
摘要翻译: 本发明涉及呋喃化合物的生物转化领域。 更具体地,本发明涉及具有改进的呋喃化合物的生物催化转化特性和适用于宿主细胞的遗传修饰的载体的新型遗传修饰细胞。 本发明的其它方面的目的在于使用本发明的细胞生物转化5-(羟甲基)呋喃-2-羧酸(HMF-酸)及其前体的方法。
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