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1.4-substituted-3-phenylsulfanylmethyl-bicyclo[3.1.0]hexane compounds as mGluR 2/3 antagonists 有权
标题翻译: 4-取代-3-苯基硫烷基甲基 - 双环[3.1.0]己烷化合物,为mGluR 2/3拮抗剂公开(公告)号:US08629169B2
公开(公告)日:2014-01-14
申请号:US13296384
申请日:2011-11-15
IPC分类号: A61K31/4196 , A61K31/216 , A61K31/196 , C07D249/12 , C07C69/96 , C07C69/757 , C07C69/753 , C07C321/28
CPC分类号: C07C323/58 , C07C2601/02 , C07C2601/08 , C07C2602/18
摘要: A mGlu2/3 receptor antagonist of the formula: its uses, and methods for its preparation are described.
摘要翻译: 描述了下式的mGlu2 / 3受体拮抗剂:其用途及其制备方法。
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2.4-SUBSTITUTED-3-PHENYLSULFANYLMETHYL-BICYCLO[3.1.0]HEXANE COMPOUNDS AS mGluR 2/3 ANTAGONISTS 有权
标题翻译: 4-取代的3-苯基甲基咪唑基双环[3.1.0] HEXANE化合物作为mGluR 2/3拮抗剂公开(公告)号:US20120129902A1
公开(公告)日:2012-05-24
申请号:US13296384
申请日:2011-11-15
IPC分类号: A61K31/4196 , C07D249/12 , A61P25/00 , A61K31/265 , A61K31/216 , A61P25/24 , C07C323/63 , A61K31/196
CPC分类号: C07C323/58 , C07C2601/02 , C07C2601/08 , C07C2602/18
摘要: A mGlu2/3 receptor antagonist of the formula: its uses, and methods for its preparation are described.
摘要翻译: 描述了下式的mGlu2 / 3受体拮抗剂:其用途及其制备方法。
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3.4-substituted-3-benzyloxy-bicyclo[3.1.0]hexane compounds as mGluR 2/3 antagonists 有权
标题翻译: 4-取代-3-苄氧基 - 双环[3.1.0]己烷化合物,为mGluR 2/3拮抗剂公开(公告)号:US09056844B2
公开(公告)日:2015-06-16
申请号:US13883788
申请日:2011-11-15
申请人: Bruce Anthony Dressman , Mark Donald Chappell , Adam Michael Fivush , Charles Howard Mitch , Paul Leslie Ornstein , Eric George Tromiczak , Tatiana Natali Vetman
发明人: Bruce Anthony Dressman , Mark Donald Chappell , Adam Michael Fivush , Charles Howard Mitch , Paul Leslie Ornstein , Eric George Tromiczak , Tatiana Natali Vetman
IPC分类号: A61K31/4196 , A61K31/426 , A61K31/216 , A61K31/4164 , C07D277/36 , A61K31/138 , A61K45/06 , C07C229/50 , C07C233/52 , C07C235/14 , C07C271/24 , A61K31/135 , A61K31/196 , A61K31/265 , A61K31/27 , C07C62/34 , C07C69/757 , C07C69/96 , C07D235/00 , C07D249/12
CPC分类号: C07D277/36 , A61K31/135 , A61K31/138 , A61K31/196 , A61K31/216 , A61K31/265 , A61K31/27 , A61K31/4164 , A61K31/4196 , A61K31/426 , A61K45/06 , C07C62/34 , C07C69/757 , C07C69/96 , C07C229/50 , C07C233/52 , C07C235/14 , C07C271/24 , C07C2601/02 , C07C2602/18 , C07D235/00 , C07D249/12 , A61K2300/00
摘要: A mGlu2/3 receptor antagonist of the formula: its uses, and methods for its preparation are described.
摘要翻译: 描述了下式的mGlu2 / 3受体拮抗剂:其用途及其制备方法。
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4.4-SUBSTITUTED-3-BENZYLOXY-BICYCLO[3.1.0]HEXANE COMPOUNDS AS mGluR 2/3 ANTAGONISTS 有权
标题翻译: 4-取代的3-苯甲酰基双环[3.1.0] HEXANE化合物作为mGluR 2/3拮抗剂公开(公告)号:US20130237573A1
公开(公告)日:2013-09-12
申请号:US13883788
申请日:2011-11-15
申请人: Bruce Anthony Dressman , Mark Donald Chappell , Adam Michael Fivush , Charles Howard Mitch , Paul Leslie Ornstein , Eric George Tromiczak , Tatiana Natali Vetman
发明人: Bruce Anthony Dressman , Mark Donald Chappell , Adam Michael Fivush , Charles Howard Mitch , Paul Leslie Ornstein , Eric George Tromiczak , Tatiana Natali Vetman
IPC分类号: C07D277/36 , A61K31/4196 , A61K31/4164 , A61K31/27 , A61K45/06 , A61K31/265 , A61K31/216 , A61K31/196 , C07D249/12 , C07D235/00 , C07C69/96 , C07C271/24 , C07C69/757 , C07C62/34 , A61K31/135 , A61K31/426
CPC分类号: C07D277/36 , A61K31/135 , A61K31/138 , A61K31/196 , A61K31/216 , A61K31/265 , A61K31/27 , A61K31/4164 , A61K31/4196 , A61K31/426 , A61K45/06 , C07C62/34 , C07C69/757 , C07C69/96 , C07C229/50 , C07C233/52 , C07C235/14 , C07C271/24 , C07C2601/02 , C07C2602/18 , C07D235/00 , C07D249/12 , A61K2300/00
摘要: A mGlu2/3 receptor antagonist of the formula: its uses, and methods for its preparation are described.
摘要翻译: 描述了下式的mGlu2 / 3受体拮抗剂:其用途及其制备方法。
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