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1.4-substituted-3-phenylsulfanylmethyl-bicyclo[3.1.0]hexane compounds as mGluR 2/3 antagonists 有权
标题翻译: 4-取代-3-苯基硫烷基甲基 - 双环[3.1.0]己烷化合物,为mGluR 2/3拮抗剂公开(公告)号:US08629169B2
公开(公告)日:2014-01-14
申请号:US13296384
申请日:2011-11-15
IPC分类号: A61K31/4196 , A61K31/216 , A61K31/196 , C07D249/12 , C07C69/96 , C07C69/757 , C07C69/753 , C07C321/28
CPC分类号: C07C323/58 , C07C2601/02 , C07C2601/08 , C07C2602/18
摘要: A mGlu2/3 receptor antagonist of the formula: its uses, and methods for its preparation are described.
摘要翻译: 描述了下式的mGlu2 / 3受体拮抗剂:其用途及其制备方法。
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2.4-SUBSTITUTED-3-PHENYLSULFANYLMETHYL-BICYCLO[3.1.0]HEXANE COMPOUNDS AS mGluR 2/3 ANTAGONISTS 有权
标题翻译: 4-取代的3-苯基甲基咪唑基双环[3.1.0] HEXANE化合物作为mGluR 2/3拮抗剂公开(公告)号:US20120129902A1
公开(公告)日:2012-05-24
申请号:US13296384
申请日:2011-11-15
IPC分类号: A61K31/4196 , C07D249/12 , A61P25/00 , A61K31/265 , A61K31/216 , A61P25/24 , C07C323/63 , A61K31/196
CPC分类号: C07C323/58 , C07C2601/02 , C07C2601/08 , C07C2602/18
摘要: A mGlu2/3 receptor antagonist of the formula: its uses, and methods for its preparation are described.
摘要翻译: 描述了下式的mGlu2 / 3受体拮抗剂:其用途及其制备方法。
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公开(公告)号:US08093239B2
公开(公告)日:2012-01-10
申请号:US12128099
申请日:2008-05-28
申请人: Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
发明人: Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
IPC分类号: A61K31/55 , A61K31/505 , A61K31/497 , A61K31/535 , C07D243/08 , C07D413/14 , C07D403/14 , C07D239/02
CPC分类号: C07D471/04
摘要: The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译: 本发明提供咪唑并吡啶化合物,含有它们的组合物,以及其制备方法和用作药剂的方法。
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公开(公告)号:US20080300242A1
公开(公告)日:2008-12-04
申请号:US12128099
申请日:2008-05-28
申请人: Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
发明人: Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
IPC分类号: A61K31/496 , C07D401/04 , C07D279/12 , A61P35/00 , A61K31/541 , A61K31/506
CPC分类号: C07D471/04
摘要: The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译: 本发明提供咪唑并吡啶化合物,含有它们的组合物,以及其制备方法和用作药剂的方法。
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公开(公告)号:US20100216779A1
公开(公告)日:2010-08-26
申请号:US12602289
申请日:2008-05-28
申请人: Eric W. Baum , Kyle Allen Emmitte , Kevin Wayne Kuntz , Robert Anthony Mook, JR. , Kristen Elizabeth Nailor , James Michael Salovich , John Brad Shotwell , Stephon Cornell Smith , Kirk Lawrence Stevens , David Edward Uehling , Alex Gregory Waterson , Mui Cheung , Ganesh S. Moorthy , Brian John Wilson
发明人: Eric W. Baum , Kyle Allen Emmitte , Kevin Wayne Kuntz , Robert Anthony Mook, JR. , Kristen Elizabeth Nailor , James Michael Salovich , John Brad Shotwell , Stephon Cornell Smith , Kirk Lawrence Stevens , David Edward Uehling , Alex Gregory Waterson , Mui Cheung , Ganesh S. Moorthy , Brian John Wilson
IPC分类号: A61K31/506 , C07D471/04 , A61K31/5377 , A61K31/551 , A61P35/00
CPC分类号: C07D471/04
摘要: The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译: 本发明提供咪唑并吡啶化合物,含有它们的组合物,以及其制备方法和用作药剂的方法。
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