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公开(公告)号：US20070167641A1
公开(公告)日：2007-07-19
申请号：US11334337
申请日：2006-01-18
申请人： Shih-Yi Wei , Yu-Chih Yeh
发明人： Shih-Yi Wei , Yu-Chih Yeh
IPC分类号： C07C59/147
CPC分类号： C07C405/00 , C07B2200/07 , C07D307/83 , C07F7/1892
摘要： The present invention provides novel processes for the preparation of a cyclopentanone of Formula II and a lactone of Formula I, which are useful in the production of prostaglandins: wherein Z, R2, R3, X1, X2, and are as defined in the specification. The invention also provides novel enantiomerically enriched compounds.
摘要翻译： 本发明提供用于制备式II的环戊酮和式I的内酯的新方法，其可用于制备前列腺素：其中Z，R 2，R 3， / SUB>，X 1，X 2和
如规范中所定义。 本发明还提供了新颖的对映异构体富集的化合物。
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2.发明申请Processes for the preparations of optically active cyclopentenones and cyclopentenones prepared therefrom 有权由其制备的光学活性环戊烯酮和环戊烯酮的制备方法公开(公告)号：US20070166809A1
公开(公告)日：2007-07-19
申请号：US11334336
申请日：2006-01-18
申请人： Yu-Chih Yeh , Ming-Kun Hsu , Shih-Yi Wei
发明人： Yu-Chih Yeh , Ming-Kun Hsu , Shih-Yi Wei
摘要： The present invention relates to novel processes for preparing optically active Cyclopentenones of Formula (R)-1, which are useful for the preparation of Prostaglandins and analogs thereof. The invention also relates to novel Cyclopentenones prepared from the processes.
摘要翻译： 本发明涉及制备式（R）-1的光学活性环戊烯酮的新方法，其可用于制备前列腺素及其类似物。 本发明还涉及由该方法制备的新型环戊烯酮。
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3.发明授权Intermediates for the synthesis of benzindene prostaglandins and preparations thereof 有权用于合成苯并茚前列腺素的中间体及其制备方法公开(公告)号：US08658837B2
公开(公告)日：2014-02-25
申请号：US13954191
申请日：2013-07-30
申请人： Shih-Yi Wei , Min-Kuan Hsu , Ming-Kun Hsu
发明人： Shih-Yi Wei , Min-Kuan Hsu , Ming-Kun Hsu
IPC分类号： C07C39/12 , C07C255/00
CPC分类号： C07F7/081 , C07C37/003 , C07C37/0555 , C07C37/50 , C07C41/26 , C07C51/08 , C07C51/09 , C07C67/283 , C07C67/297 , C07C69/017 , C07C69/18 , C07C69/78 , C07C255/13 , C07C2603/14 , C07F7/1804 , Y02P20/55 , C07C39/23 , C07C39/17 , C07C43/23 , C07C69/732 , C07C59/72
摘要： Novel processes for preparing optically active cyclopentanones 1 which are useful for the preparation of benzindene Prostaglandins and novel cyclopentanones are provided. The invention also provides novel processes of preparing benzindene Prostaglandins and novel intermediates for benzindene Prostaglandins.
摘要翻译： 提供了可用于制备苯撑前列腺素和新型环戊烷酮的光学活性环戊酮1的新方法。 本发明还提供了制备苯并茚前列腺素的新方法和苯并ene前列腺素的新中间体。
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4.发明授权Intermediates for the synthesis of benzindene prostaglandins and preparations thereof 有权用于合成苯并茚前列腺素的中间体及其制备方法公开(公告)号：US08524939B2
公开(公告)日：2013-09-03
申请号：US13216378
申请日：2011-08-24
申请人： Shih-Yi Wei , Min-Kuan Hsu , Ming-Kun Hsu
发明人： Shih-Yi Wei , Min-Kuan Hsu , Ming-Kun Hsu
IPC分类号： C07C51/09
CPC分类号： C07F7/081 , C07C37/003 , C07C37/0555 , C07C37/50 , C07C41/26 , C07C51/08 , C07C51/09 , C07C67/283 , C07C67/297 , C07C69/017 , C07C69/18 , C07C69/78 , C07C255/13 , C07C2603/14 , C07F7/1804 , Y02P20/55 , C07C39/23 , C07C39/17 , C07C43/23 , C07C69/732 , C07C59/72
摘要： Novel processes for preparing optically active cyclopentanones 1 which are useful for the preparation of benzindene Prostaglandins and novel cyclopentanones are provided. The invention also provides novel processes of preparing benzindene Prostaglandins and novel intermediates for benzindene Prostaglandins.
摘要翻译： 提供了可用于制备苯撑前列腺素和新型环戊烷酮的光学活性环戊酮1的新方法。 本发明还提供了制备苯并茚前列腺素的新方法和苯并ene前列腺素的新中间体。
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公开(公告)号：US08030514B2
公开(公告)日：2011-10-04
申请号：US12538924
申请日：2009-08-11
申请人： Shih-Yi Wei , Yu-Chih Yeh
发明人： Shih-Yi Wei , Yu-Chih Yeh
IPC分类号： C07C69/74
CPC分类号： C07C405/00 , C07B2200/07 , C07D307/83 , C07F7/1892
摘要： The present invention provides novel processes for the preparation of a cyclopentanone of Formula II and a lactone of Formula I, which are useful in the production of prostaglandins: wherein Z, R2, R3, X1, X2, and are as defined in the specification. The invention also provides novel enantiomerically enriched compounds.
摘要翻译： 本发明提供了用于制备式II的环戊酮和式I的内酯的新方法，其可用于制备前列腺素：其中Z，R2，R3，X1，X2和如说明书中所定义。 本发明还提供了新颖的对映异构体富集的化合物。
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公开(公告)号：US20130317245A1
公开(公告)日：2013-11-28
申请号：US13954191
申请日：2013-07-30
申请人： Shih-Yi WEI , Min-Kuan HSU , Ming-Kun HSU
发明人： Shih-Yi WEI , Min-Kuan HSU , Ming-Kun HSU
IPC分类号： C07F7/08 , C07C255/13 , C07C69/017 , C07C37/055
CPC分类号： C07F7/081 , C07C37/003 , C07C37/0555 , C07C37/50 , C07C41/26 , C07C51/08 , C07C51/09 , C07C67/283 , C07C67/297 , C07C69/017 , C07C69/18 , C07C69/78 , C07C255/13 , C07C2603/14 , C07F7/1804 , Y02P20/55 , C07C39/23 , C07C39/17 , C07C43/23 , C07C69/732 , C07C59/72
摘要： Novel processes for preparing optically active cyclopentanones 1 which are useful for the preparation of benzindene Prostaglandins and novel cyclopentanones are provided. The invention also provides novel processes of preparing benzindene Prostaglandins and novel intermediates for benzindene Prostaglandins.
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7.发明申请公开(公告)号：US20130053581A1
公开(公告)日：2013-02-28
申请号：US13216378
申请日：2011-08-24
申请人： Shih-Yi WEI , Min-Kuan Hsu , Ming-Kun Hsu
发明人： Shih-Yi WEI , Min-Kuan Hsu , Ming-Kun Hsu
IPC分类号： C07C51/09 , C07C51/08 , C07C69/78 , C07C255/16 , C07C69/017 , C07F7/18 , C07C37/00
CPC分类号： C07F7/081 , C07C37/003 , C07C37/0555 , C07C37/50 , C07C41/26 , C07C51/08 , C07C51/09 , C07C67/283 , C07C67/297 , C07C69/017 , C07C69/18 , C07C69/78 , C07C255/13 , C07C2603/14 , C07F7/1804 , Y02P20/55 , C07C39/23 , C07C39/17 , C07C43/23 , C07C69/732 , C07C59/72
摘要： Novel processes for preparing optically active cyclopentanones 1 which are useful for the preparation of benzindene Prostaglandins and novel cyclopentanones are provided. The invention also provides novel processes of preparing benzindene Prostaglandins and novel intermediates for benzindene Prostaglandins.
摘要翻译： 提供了可用于制备苯撑前列腺素和新型环戊烷酮的光学活性环戊酮1的新方法。 本发明还提供了制备苯并茚前列腺素的新方法和苯并ene前列腺素的新中间体。
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8.发明授权Processes for preparing cyclopentenones and cyclopentenones for the synthesis of benzindene prostaglandins 有权制备环戊烯酮和环戊烯酮合成苯并茚前列腺素的方法公开(公告)号：US08350090B1
公开(公告)日：2013-01-08
申请号：US13216321
申请日：2011-08-24
申请人： Shih-Yi Wei , Wan-Chun Chang , Yu-Chih Yeh
发明人： Shih-Yi Wei , Wan-Chun Chang , Yu-Chih Yeh
CPC分类号： C12P7/26 , C07C45/59 , C12P7/22 , C12P41/004 , Y02P20/55 , C07C49/753
摘要： The present invention provides novel processes of preparing racemic and optically active cyclopentenones of Formula I: The invention also provides novel cyclopentenones of formula I in racemic or optically active form.
摘要翻译： 本发明提供制备式I的外消旋和光学活性环戊烯酮的新方法：本发明还提供外消旋或光学活性形式的新颖的式I的环戊烯酮。
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9.发明申请公开(公告)号：US20090299088A1
公开(公告)日：2009-12-03
申请号：US12538924
申请日：2009-08-11
申请人： Shih-Yi WEI , Yu-Chih Yeh
发明人： Shih-Yi WEI , Yu-Chih Yeh
IPC分类号： C07C69/738
CPC分类号： C07C405/00 , C07B2200/07 , C07D307/83 , C07F7/1892
摘要： The present invention provides novel processes for the preparation of a cyclopentanone of Formula II and a lactone of Formula I, which are useful in the production of prostaglandins: wherein Z, R2, R3, X1, X2, and are as defined in the specification.The invention also provides novel enantiomerically enriched compounds.
摘要翻译： 本发明提供用于制备式II的环戊酮和式I的内酯的新方法，其可用于制备前列腺素：其中Z，R2，R3，X1，X2和
如规范中所定义。 本发明还提供了新颖的对映异构体富集的化合物。
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公开(公告)号：US07626024B2
公开(公告)日：2009-12-01
申请号：US11973494
申请日：2007-10-09
申请人： Shih-Yi Wei , Yu-Chih Yeh
发明人： Shih-Yi Wei , Yu-Chih Yeh
IPC分类号： C07D241/36
CPC分类号： C07C405/00 , C07B2200/07 , C07D307/83 , C07F7/1892
摘要： The present invention provides novel processes for the preparation of a cyclopentanone of Formula II and a lactone of Formula I, which are useful in the production of prostaglandins: wherein Z, R2, R3, X1, X2, and are as defined in the specification. The invention also provides novel enantiomerically enriched compounds.
摘要翻译： 本发明提供用于制备式II的环戊酮和式I的内酯的新方法，其可用于制备前列腺素：其中Z，R2，R3，X1，X2和
如说明书中所定义。 本发明还提供了新颖的对映异构体富集的化合物。
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