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    Polymer scaffold degradation control via chemical control
    1.
    发明授权
    Polymer scaffold degradation control via chemical control 有权
    通过化学控制的聚合物支架降解控制

    公开(公告)号：US09228042B2

    公开(公告)日：2016-01-05

    申请号：US14147983

    申请日：2014-01-06

    Applicant: Elizabeth L Hedberg-Dirk ,  Shawn Dirk ,  Kirsten Cicotte

    Inventor： Elizabeth L Hedberg-Dirk ,  Shawn Dirk ,  Kirsten Cicotte

    IPC: C08G63/52 ,  C08F222/10

    CPC classification number: C08G63/52 ,  C08F222/10

    Abstract: A variety of polymers and copolymers suitable for use as biologically compatible constructs and, as a non-limiting specific example, in the formation of degradable tissue scaffolds as well methods for synthesizing these polymers and copolymers are described. The polymers and copolymers have degradation rates that are substantially faster than those of previously described polymers suitable for the same uses. Copolymers having a synthesis route which enables one to fine tune the degradation rate by selecting the specific stoichiometry of the monomers in the resulting copolymer are also described. The disclosure also provides a novel synthesis route for maleoyl chloride which yields monomers suitable for use in the copolymer synthesis methods described herein.

    Abstract translation: 描述适合用作生物相容性构建体的多种聚合物和共聚物，以及作为非限制性具体实例的可降解组织支架的形成以及用于合成这些聚合物和共聚物的方法。 聚合物和共聚物的降解速率明显快于适用于相同用途的前述聚合物的降解速率。 还描述了具有能够通过选择所得共聚物中单体的特定化学计量来微调降解速率的合成途径的共聚物。 本公开还提供了一种用于马来酰氯的新型合成路线，其产生适用于本文所述共聚物合成方法的单体。

    Polymer scaffold degradation control via chemical control
    3.
    发明授权
    Polymer scaffold degradation control via chemical control 有权
    聚合物支架降解控制通过化学控制

    公开(公告)号：US08648167B1

    公开(公告)日：2014-02-11

    申请号：US13439661

    申请日：2012-04-04

    Applicant: Elizabeth L Hedberg-Dirk ,  Shawn Dirk ,  Kirsten Cicotte

    Inventor： Elizabeth L Hedberg-Dirk ,  Shawn Dirk ,  Kirsten Cicotte

    IPC: C08G63/52

    CPC classification number: C08G63/52 ,  C08F222/10

    Abstract: A variety of polymers and copolymers suitable for use as biologically compatible constructs and, as a non-limiting specific example, in the formation of degradable tissue scaffolds as well methods for synthesizing these polymers and copolymers are described. The polymers and copolymers have degradation rates that are substantially faster than those of previously described polymers suitable for the same uses. Copolymers having a synthesis route which enables one to fine tune the degradation rate by selecting the specific stoichiometry of the monomers in the resulting copolymer are also described. The disclosure also provides a novel synthesis route for maleoyl chloride which yields monomers suitable for use in the copolymer synthesis methods described herein.

    Abstract translation: 描述适合用作生物相容性构建体的多种聚合物和共聚物，以及作为非限制性具体实例的可降解组织支架的形成以及用于合成这些聚合物和共聚物的方法。 聚合物和共聚物的降解速率明显快于适用于相同用途的前述聚合物的降解速率。 还描述了具有能够通过选择所得共聚物中单体的特定化学计量来微调降解速率的合成途径的共聚物。 本公开还提供了一种用于马来酰氯的新型合成路线，其产生适用于本文所述共聚物合成方法的单体。

    Polymer Scaffold Degradation Control Via Chemical Control
    5.
    发明申请
    Polymer Scaffold Degradation Control Via Chemical Control 审中-公开
    通过化学控制的聚合物支架降解控制

    公开(公告)号：US20160152766A1

    公开(公告)日：2016-06-02

    申请号：US14956521

    申请日：2015-12-02

    Applicant: Elizabeth L Dirk ,  Shawn Dirk ,  Kirsten Cicotte

    Inventor： Elizabeth L Dirk ,  Shawn Dirk ,  Kirsten Cicotte

    IPC: C08G63/52

    CPC classification number: C08G63/52 ,  C08F222/10

    Abstract: A variety of polymers and copolymers suitable for use as biologically compatible constructs and, as a non-limiting specific example, in the formation of degradable tissue scaffolds as well methods for synthesizing these polymers and copolymers are described. The polymers and copolymers have degradation rates that are substantially faster than those of previously described polymers suitable for the same uses. Copolymers having a synthesis route which enables one to fine tune the degradation rate by selecting the specific stoichiometry of the monomers in the resulting copolymer are also described. The disclosure also provides a novel synthesis route for maleoyl chloride which yields monomers suitable for use in the copolymer synthesis methods described herein.

    Abstract translation: 描述适合用作生物相容性构建体的多种聚合物和共聚物，以及作为非限制性具体实例的可降解组织支架的形成以及用于合成这些聚合物和共聚物的方法。 聚合物和共聚物的降解速率明显快于适用于相同用途的前述聚合物的降解速率。 还描述了具有能够通过选择所得共聚物中单体的特定化学计量来微调降解速率的合成途径的共聚物。 本公开还提供了一种用于马来酰氯的新型合成路线，其产生适用于本文所述共聚物合成方法的单体。

    Polymer Scaffold Degradation Control Via Chemical Control
    6.
    发明申请
    Polymer Scaffold Degradation Control Via Chemical Control 有权
    通过化学控制的聚合物支架降解控制

    公开(公告)号：US20140121328A1

    公开(公告)日：2014-05-01

    申请号：US14147983

    申请日：2014-01-06

    Applicant: Elizabeth L Hedberg-Dirk ,  Shawn Dirk ,  Kirsten Cicotte

    Inventor： Elizabeth L Hedberg-Dirk ,  Shawn Dirk ,  Kirsten Cicotte

    IPC: C08F222/10

    CPC classification number: C08G63/52 ,  C08F222/10

    Abstract: A variety of polymers and copolymers suitable for use as biologically compatible constructs and, as a non-limiting specific example, in the formation of degradable tissue scaffolds as well methods for synthesizing these polymers and copolymers are described. The polymers and copolymers have degradation rates that are substantially faster than those of previously described polymers suitable for the same uses. Copolymers having a synthesis route which enables one to fine tune the degradation rate by selecting the specific stoichiometry of the monomers in the resulting copolymer are also described. The disclosure also provides a novel synthesis route for maleoyl chloride which yields monomers suitable for use in the copolymer synthesis methods described herein.

    Abstract translation: 描述适合用作生物相容性构建体的多种聚合物和共聚物，以及作为非限制性具体实例的可降解组织支架的形成以及用于合成这些聚合物和共聚物的方法。 聚合物和共聚物的降解速率明显快于适用于相同用途的前述聚合物的降解速率。 还描述了具有能够通过选择所得共聚物中单体的特定化学计量来微调降解速率的合成途径的共聚物。 本公开还提供了一种用于马来酰氯的新型合成路线，其产生适用于本文所述共聚物合成方法的单体。

    Molecular electronic interconnects
    7.
    发明申请
    Molecular electronic interconnects 审中-公开
    分子电子互连

    公开(公告)号：US20050233158A1

    公开(公告)日：2005-10-20

    申请号：US10502601

    申请日：2002-07-26

    Applicant: James Tour ,  Shawn Dirk

    Inventor： James Tour ,  Shawn Dirk

    IPC: B32B15/04 ,  B32B27/32 ,  H01L51/00 ,  H01R13/03

    CPC classification number: B82Y30/00 ,  B82Y10/00 ,  H01L51/005 ,  H01L51/0595 ,  H01R13/03 ,  Y10T428/31678 ,  Y10T428/31855 ,  Y10T428/31931

    Abstract: An electrical interconnect device with contact(s) with improved resistance to oxidation, improved conductivity, and improved lubricity achieved by applying to the surface of the contact(s) a molecular coating chosen from the group consisting of monomers, oligomers, or polymers that are primarily organic in origin, capable of forming self-assembled monolayers or self-assembled multilayers, electrically conducting or non-conducting, and contain metal-binding ligands as pendant groups or as part of their backbone. Alternatively, the molecular contact coating may be a mat of chemically modified nanotubes.

    Abstract translation: 具有改善的抗氧化性，改善的导电性和改善的润滑性的电接头的电互连装置通过将接触的表面施加到选自单体，低聚物或聚合物的分子涂层 主要有机原产地，能够形成自组装单层或自组装多层，导电或不导电，并且含有金属结合配体作为侧基或作为其主链的一部分。 或者，分子接触涂层可以是化学修饰的纳米管的垫。

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