ANTI-INFLAMMATORY PEPTIDES AND COMPOSITION COMPRISING THE SAME

    公开(公告)号:US20210388328A1

    公开(公告)日:2021-12-16

    申请号:US17389671

    申请日:2021-07-30

    IPC分类号: C12N9/12 A23L33/18 A61K38/45

    摘要: The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. The present invention also relates to an inflammatory composition comprising the above mentioned peptides. According to the present invention, a peptide that has at least one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161 has outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising the peptides of this invention can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases.

    Composition for treating prostate cancer

    公开(公告)号:US11058744B2

    公开(公告)日:2021-07-13

    申请号:US15105289

    申请日:2014-12-17

    发明人: Sang Jae Kim

    摘要: The present invention relates to a composition for treating prostate cancer and, more specifically, to a composition for treating prostate cancer, which contains a peptide derived from telomerase and is effective in inhibiting growth and metastasis of prostate cancer cells. In addition, the present invention provides a composition and method for treating prostate cancer, wherein, when prostate cancer is treated, docetaxel and the peptide derived from telomerase are co-administered, thereby having a synergetic therapeutic effect compared with administration alone. Particularly, the present invention provides a treatment method useful for patients who do not have a sufficient anticancer effect merely through administration of docetaxel alone and patients who have hormone resistance.

    Biological markers useful in cancer immunotherapy

    公开(公告)号:US10383926B2

    公开(公告)日:2019-08-20

    申请号:US14896358

    申请日:2014-06-05

    发明人: Sang Jae Kim

    摘要: Methods are disclosed that are based on the finding that serum and plasma levels of eotaxin, MIP1α, and CRP act as important biomarkers that are useful for determining the feasibility in instigating immunotherapeutic treatment of cancer when immunizing with the GV1001 peptide (EARPALLTSRLRFIPK; derived from human telomerase protein), optionally when combined with state of the art combination treatment with Gemcitabine and Capecitabine. In particular, the present invention provides methods for determining whether patients should be treated GV1001 and for determining whether instigated treatment should be continued.

    Display apparatus
    10.
    发明授权
    Display apparatus 有权
    显示装置

    公开(公告)号:US09091884B2

    公开(公告)日:2015-07-28

    申请号:US13327274

    申请日:2011-12-15

    摘要: A display apparatus including a first insulating substrate, a plurality of pixels, a second insulating substrate, a color filter layer, and a pattern retarder. The first insulating substrate includes a plurality of pixel areas arranged in an array of rows and columns, which has a length in the row direction longer than a length in the column direction, and has a length in a row direction longer than a length in a column direction. The pixels are arranged in the pixel areas, respectively, to display a 2D image and a 3D image. Among the pixels, first to fourth pixels successively arranged in the column direction define a unit pixel that displays one color information, and the fourth pixel corresponds to the white color pixel.

    摘要翻译: 一种显示装置,包括第一绝缘基板,多个像素,第二绝缘基板,滤色器层和图案延迟器。 第一绝缘基板包括排列成行和列的阵列的多个像素区域,该多个像素区域的行方向的长度比列方向上的长度长,并且具有比沿着列方向的长度长的行方向的长度 列方向。 像素分别布置在像素区域中以显示2D图像和3D图像。 在像素中,在列方向上连续布置的第一至第四像素限定显示一个颜色信息的单位像素,并且第四像素对应于白色像素。