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    Tissue modification devices and methods
    3.
    发明授权
    Tissue modification devices and methods 有权
    组织修饰装置及方法

    公开(公告)号：US08409206B2

    公开(公告)日：2013-04-02

    申请号：US12773595

    申请日：2010-05-04

    Applicant: Michael P. Wallace ,  Robert Garabedian ,  Nestor C. Cantorna ,  Jeffery L. Bleich ,  Roy Leguidleguid ,  Ronald Leguidleguid

    Inventor： Michael P. Wallace ,  Robert Garabedian ,  Nestor C. Cantorna ,  Jeffery L. Bleich ,  Roy Leguidleguid ,  Ronald Leguidleguid

    IPC: A61B17/00

    CPC classification number: A61B17/025 ,  A61B5/4893 ,  A61B17/0218 ,  A61B17/7062 ,  A61B2017/0256 ,  A61B2017/32006 ,  A61M25/01 ,  A61M25/0105 ,  A61M25/0133 ,  A61M25/0136 ,  A61M25/09 ,  A61M29/02

    Abstract: Described herein are devices, systems and methods for cutting tissue in a patient. In some embodiments, a tissue modification region of a device includes a pair of flexible elongate cutting members extending along the length of the tissue modification region. Each elongate cutting member may be configured to cut a discrete trough into tissue to a depth that is greater than the thickness of the cutting member. In some embodiments, the device includes a spacer. The spacer may be sized and configured to operate in one of two modes. A first mode, in which the spacer is coupled to the cutting members such that it holds a portion of each of the two cutting members a distance from one another, and a second mode, in which at least a portion of the spacer is moved away from a cutting member to allow the cutting members to cut further into tissue.

    Abstract translation: 这里描述了用于切割患者组织的装置，系统和方法。 在一些实施例中，装置的组织修改区域包括沿着组织修改区域的长度延伸的一对柔性细长切割构件。 每个细长的切割构件可以被配置成将离散的槽切割成组织到比切割构件的厚度大的深度。 在一些实施例中，该装置包括间隔件。 间隔件的尺寸和构造可以以两种模式之一来操作。 第一模式，其中间隔件联接到切割构件，使得其将两个切割构件中的每一个的一部分保持彼此的距离，以及第二模式，其中至少一部分间隔件移开 从切割构件允许切割构件进一步切割成组织。

    Catheter With Knit Section
    5.
    发明申请
    Catheter With Knit Section 有权
    导管与针织部分

    公开(公告)号：US20110024025A1

    公开(公告)日：2011-02-03

    申请号：US12906872

    申请日：2010-10-18

    Applicant: Jill M. McFadden ,  Earl Bardsley ,  Robert Garabedian

    Inventor： Jill M. McFadden ,  Earl Bardsley ,  Robert Garabedian

    IPC: B29C70/10

    CPC classification number: A61M25/0045 ,  A61B5/6852 ,  A61M25/0053 ,  A61M25/0054 ,  Y10T29/49801

    Abstract: A catheter section comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member includes a knit tubular member and an inner tubular liner in coaxial relationship with the knit tubular member. The catheter section is for use as a distal section in a catheter having a relatively stiff proximal section.

    Abstract translation: 一种导管部分，包括细长的管状部件，其具有近端，远端以及限定在近端和远端之间延伸的内腔的通道。 细长管状构件包括编织管状构件和与针织管状构件同轴关系的内部管状衬垫。 导管部分用作具有相对刚性近端部分的导管中的远侧部分。

    LIQUID INFUSION APPARATUS FOR RADIOFREQUENCY TISSUE ABLATION
    7.
    发明申请
    LIQUID INFUSION APPARATUS FOR RADIOFREQUENCY TISSUE ABLATION 有权
    用于放射性组织消融的液体输注装置

    公开(公告)号：US20080071266A1

    公开(公告)日：2008-03-20

    申请号：US11944257

    申请日：2007-11-21

    Applicant: Robert Rioux ,  Robert Garabedian ,  Christopher Pearson

    Inventor： Robert Rioux ,  Robert Garabedian ,  Christopher Pearson

    IPC: A61B18/14

    CPC classification number: A61B18/1477 ,  A61B2018/00065 ,  A61B2018/1472 ,  A61B2018/1475

    Abstract: An apparatus for delivering electrical energy includes a cannula and one or more needles extendable from and retractable into a lumen of the cannula. A distal portion of each needle is extendable from the lumen and terminates in a tissue-piercing distal tip. Each distal portion is formed from an electrically conductive and porous material, thereby providing a porous electrode through which electrolytic fluid may flow for delivering electrical energy to tissue surrounding the distal portion. The cannula is introduced into a tissue structure of a patient, the one or more needles are advanced from the cannula, saline is introduced from the porous material to surrounding tissue, and electrical energy from an RF generator is delivered to ablate tissue within the tissue structure.

    Abstract translation: 用于递送电能的装置包括套管和一个或多个可从套管的内腔中伸出并可收缩的针。 每个针的远端部分可从内腔延伸并终止于组织刺穿的远端。 每个远端部分由导电和多孔材料形成，从而提供多孔电极，电解液可通过该多孔电极流动，用于将电能传递到围绕远端部分的组织。 将套管引入患者的组织结构中，一个或多个针从套管前进，盐水从多孔材料引入周围组织，并且来自RF发生器的电能被输送以烧蚀组织结构内的组织 。

    RADIO FREQUENCY ABLATION COOLING SHIELD
    8.
    发明申请
    RADIO FREQUENCY ABLATION COOLING SHIELD 审中-公开
    无线电频率冷却屏蔽

    公开(公告)号：US20060271036A1

    公开(公告)日：2006-11-30

    申请号：US11462961

    申请日：2006-08-07

    Applicant: Robert Garabedian ,  Robert Rioux

    Inventor： Robert Garabedian ,  Robert Rioux

    IPC: A61B18/14

    CPC classification number: A61B18/1477 ,  A61B18/14 ,  A61B90/04 ,  A61B2018/00005 ,  A61B2018/00017 ,  A61B2018/00023 ,  A61B2018/00029 ,  A61B2018/00577 ,  A61B2090/0445 ,  A61B2090/0481

    Abstract: A medical assembly and method are provided to effectively treat abnormal tissue, such as, a tumor. The target tissue is thermally ablated using a suitable source, such as RF or laser energy. A cooling shield is placed in contact with non-target tissue adjacent the target tissue, and actively cooled to conduct thermal energy away from the non-target tissue. In one method, the cooling shield can be placed between two organs, in which case, one of the two organs can comprise the target tissue, and the other of the two organs can comprise the non-target tissue. In this case, the cooling shield may comprise an actively cooled inflatable balloon, which can be disposed between the two organs when deflated, and then inflated. The inflatable balloon can be actively cooled by pumping a cooling medium through it. In another method, the cooling shield can be embedded within the non-target tissue. In this case, the cooling shield can comprise one or more needles. If a plurality of needles is used, they can be embedded into the non-target tissue in a series, e.g., a rectilinear or curvilinear arrangement. The needle(s) can be actively cooled by pumping a cooling medium through them.

    Abstract translation: 提供医疗组件和方法来有效地治疗诸如肿瘤的异常组织。 使用适当的来源（例如RF或激光能量）将靶组织热消融。 将冷却屏蔽物放置成与目标组织相邻的非靶组织接触，并且主动冷却以将热能从非目标组织传导出去。 在一种方法中，冷却屏蔽可以放置在两个器官之间，在这种情况下，两个器官中的一个可以包括靶组织，并且两个器官中的另一个可以包括非靶组织。 在这种情况下，冷却屏蔽件可以包括主动冷却的可膨胀气囊，当气体放气时可以将气囊放置在两个器官之间，然后膨胀。 可以通过泵送冷却介质来主动冷却可充气球囊。 在另一种方法中，冷却屏蔽可以嵌入在非目标组织内。 在这种情况下，冷却罩可以包括一个或多个针。 如果使用多个针，则它们可以以一系列例如直线或曲线布置被嵌入到非目标组织中。 可以通过将冷却介质泵送通过它们来主动冷却针。

    Collapsible/Expandable Tubular Electrode Leads
    9.
    发明申请
    Collapsible/Expandable Tubular Electrode Leads 有权
    可折叠/可扩展管状电极引线

    公开(公告)号：US20060259110A1

    公开(公告)日：2006-11-16

    申请号：US11459618

    申请日：2006-07-24

    Applicant: Michael Wallace ,  Robert Garabedian

    Inventor： Michael Wallace ,  Robert Garabedian

    IPC: A61N1/05

    CPC classification number: A61N1/0553

    Abstract: A medical lead and method of treating a patient are provided. The medical lead comprises an electrically insulative tubular membrane, a resilient spring element associated with the insulative membrane, and at least one electrode associated with the insulative membrane. The medical lead is configured to be collapsed into a compact form for percutaneous delivery into the patient, thereby obviating the need to perform an invasive surgical procedure on the patient. The body formed by these elements, when expanded, can be sized to fit within the epidural space of a patient. The patient can be treated by placing the medical lead into a collapsed state by applying a compressive force to the medical lead, percutaneously delivering the collapsed medical lead into the patient adjacent tissue to be treated, and placing the medical lead into an expanded state by releasing the compressive force. In one preferred method, the stimulation lead is used to stimulate tissue, such as spinal cord tissue.

    Abstract translation: 提供医疗用铅和治疗患者的方法。 医用引线包括电绝缘管状膜，与绝缘膜相关联的弹性弹簧元件以及与绝缘膜相关联的至少一个电极。 医疗用引线被构造成塌缩成紧密形式用于经皮输送到患者体内，从而避免了对患者执行侵入性外科手术的需要。 由这些元件形成的身体，当扩张时，其尺寸可以适合于患者的硬膜外腔内。 可以通过向医用引线施加压缩力将医用引线置于折叠状态来将患者放置在患者身体中，将经塌陷的医用导管经皮递送到邻近被治疗组织的患者中，并通过释放将医用引线放入扩张状态 压缩力。 在一种优选的方法中，刺激引线用于刺激组织，例如脊髓组织。

    Manually advanceable radio frequency array with tactile feel
    10.
    发明申请
    Manually advanceable radio frequency array with tactile feel 审中-公开
    手动推进无线电频率阵列具有触觉

    公开(公告)号：US20060095033A1

    公开(公告)日：2006-05-04

    申请号：US11273950

    申请日：2005-11-14

    Applicant: Robert Garabedian ,  Robert Rioux

    Inventor： Robert Garabedian ,  Robert Rioux

    IPC: A61B18/14

    CPC classification number: A61B18/1482 ,  A61B90/50 ,  A61B2018/1467 ,  A61B2018/1475 ,  A61N1/06

    Abstract: A system for ablating lesions in the interior regions of the human body including a RF catheter and a control system adapted to facilitate the automatic step deployment of an array-type energy delivery system positioned within the catheter. The RF catheter and control system further include an auto array deployment mechanism coupled to the array-type energy delivery system and an impedance and temperature monitoring system. In addition, the system includes a probe positioning device adapted to maintain a RF probe in a desired orientation during ablation procedures.

    Abstract translation: 一种用于消除人体内部区域中的损伤的系统，包括RF导管和适于便于定位在导管内的阵列型能量输送系统的自动步骤部署的控制系统。 RF导管和控制系统还包括耦合到阵列型能量输送系统的自动阵列展开机构和阻抗和温度监测系统。 此外，该系统包括探针定位装置，其适于在消融过程期间将RF探针保持在期望的取向。

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