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    Installable graffiti and tagging inhibiting panels
    1.
    发明授权
    Installable graffiti and tagging inhibiting panels 有权

    公开(公告)号：US09624674B2

    公开(公告)日：2017-04-18

    申请号：US14120677

    申请日：2014-06-16

    申请人： Phillip Lee

    发明人： Phillip Lee

    IPC分类号： E04F13/072 ,  E04F13/08 ,  E04F13/12

    CPC分类号： E04F13/072 ,  E01D19/103 ,  E04F13/0814 ,  E04F13/0862 ,  E04F13/0871 ,  E04F13/12 ,  E04F2203/00

    摘要： A baffle formed of square tubing having four faces, each face having a series of openings therein, The baffles are joined in off set rows and offset columns, with a space between each pair of baffles, vertically and horizontally, preferably in rows of six to form an anti-graffiti baffle assembly that has thirty six baffles therein. The individual baffles can be welded or otherwise attached to each other to form the baffle assembly, and which assembly is attached to either a substrate to be protected, or attached to a pair of spaced mounting posts which in turn are mounted to a substrate by four flat plates that are strategically attached to the baffle assembly to act as a mounting means.

    POLYMER-PHOSPHOLIPID SHELLED MICROBUBBLES
    3.
    发明申请
    POLYMER-PHOSPHOLIPID SHELLED MICROBUBBLES 审中-公开
    聚合物 - 磷脂微粉体

    公开(公告)号：US20110045095A1

    公开(公告)日：2011-02-24

    申请号：US12911321

    申请日：2010-10-25

    申请人： Kanaka Hettiarachchi ,  Abraham Phillip Lee

    发明人： Kanaka Hettiarachchi ,  Abraham Phillip Lee

    IPC分类号： A61K9/14 ,  A61M37/00

    CPC分类号： B01J13/04 ,  A61K49/225 ,  B01J13/22

    摘要： A multiple layer microfluidic system and multiple layer microbubble are disclosed. The microfluidic system for producing multiple layer microbubbles includes a first inlet which receives a gas and directs the gas into a central stream, a second inlet which receives an oil and flow focuses the oil around the gas, a third inlet which receives a polymer and lipid solution and flow focuses the polymer and lipid solution around the oil and a fourth inlet which receives a surfactant solution and flow focuses the surfactant solution around the polymer and lipid solution. The multiple layer microbubble includes a gas core, a polymer and lipid shell surrounding the gas core and a surfactant layer surrounding shell.

    摘要翻译： 公开了一种多层微流体系统和多层微泡。 用于生产多层微泡的微流体系统包括接收气体并将气体引导到中心流中的第一入口，接收油的第二入口和将气体聚焦在气体周围的油，接收聚合物和脂质的第三入口 溶液和流动将聚合物和脂质溶液聚焦在油周围，并且接收表面活性剂溶液和流动的第四个入口将表面活性剂溶液聚焦在聚合物和脂质溶液周围。 多层微泡包括气芯，围绕气芯的聚合物和脂壳以及围绕壳的表面活性剂层。

    Microfluidic device for forming monodisperse lipoplexes
    5.
    发明授权
    Microfluidic device for forming monodisperse lipoplexes 有权
    用于形成单分散脂质复合物的微流体装置

    公开(公告)号：US07811603B2

    公开(公告)日：2010-10-12

    申请号：US11746024

    申请日：2007-05-08

    申请人： Abraham Phillip Lee ,  Albert Tsung-Hsi Hsieh

    发明人： Abraham Phillip Lee ,  Albert Tsung-Hsi Hsieh

    IPC分类号： A61K9/127

    CPC分类号： A61K9/1272 ,  A61K9/1277 ,  A61K31/70 ,  B01L3/0241 ,  B01L3/502784 ,  B01L2200/0673 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0883 ,  B01L2400/0421 ,  B01L2400/0424 ,  B01L2400/0436 ,  B01L2400/0478

    摘要： A method for forming monodisperse lipoplex assemblies includes providing a microfluidic device having a main microfluidic channel coupled to first and second reactant inlet channels. The first inlet channel is used to deliver a cationic lipid to the main channel while the second channel is used to deliver a nucleic acid. A droplet generation zone is provided in the main channel at the intersection of first and second carrier channels that contain a hydrophobic fluid. The cationic lipid, nucleic acid, and the hydrophobic fluid are then pumped through the device. In the droplet generation zone, shear force from the hydrophobic fluid pinches off droplets. The cationic lipid and nucleic acid are mixed in the generated droplets as the droplets move within a mixing region. A plurality of splitting channels may be coupled to the outlet of the device to produce smaller, monodisperse droplets having picoliter volumes.

    摘要翻译： 形成单分散脂质复合组件的方法包括提供具有与第一和第二反应物入口通道耦合的主微流体通道的微流体装置。 第一入口通道用于将阳离子脂质递送至主通道，而第二通道用于递送核酸。 在主通道中，在包含疏水性流体的第一和第二载体通道的相交处设置液滴产生区。 然后将阳离子脂质，核酸和疏水性流体泵送通过该装置。 在液滴产生区域，来自疏水性流体的剪切力挤压液滴。 当液滴在混合区域内移动时，阳离子脂质和核酸在产生的液滴中混合。 多个分离通道可以连接到装置的出口，以产生具有皮升体积的较小的单分散液滴。