公开(公告)号：US20110183370A1

公开(公告)日：2011-07-28

申请号：US13011239

申请日：2011-01-21

申请人： Isabelle NOISEUX ,  Pascal GALLANT ,  Ozzy MERMUT ,  Marcia VERNON

发明人： Isabelle NOISEUX ,  Pascal GALLANT ,  Ozzy MERMUT ,  Marcia VERNON

IPC分类号： C12Q1/04 ,  C12M1/34

CPC分类号： C12Q1/04 ,  G01N33/582 ,  G01N33/587

摘要： An optical detection system for identifying target bacterial cells in a food sample, comprising a first fluorescent nanoparticle dye labeling specifically the target cells. A second fluorescent dye reacts non-specifically with all bacterial cells. An imaging unit optically excites the fluorescent dyes and captures images of the sample for each of two different wavelength bands emitted as a result of the excitation of the dyes. A processing unit identifies the target cells from the sample and comprises an image processing unit for processing the images of the sample. A target cell identifier identifies the target cells in the images by detecting individual units present at a same location in both of the processed images. An output unit provides data related to the identified target cells in the sample. A method is also provided.

摘要翻译： 一种用于鉴定食品样品中的目标细菌细胞的光学检测系统，包括特别标记靶细胞的第一荧光纳米颗粒染料。 第二种荧光染料与所有细菌细胞非特异性地反应。 成像单元光学地激发荧光染料并且捕获作为染料激发的结果发射的两个不同波长带中的每一个的样品的图像。 处理单元从样本识别目标单元，并且包括用于处理样本的图像的图像处理单元。 目标小区标识符通过检测存在于两个处理的图像中的相同位置处的单个单元来识别图像中的目标小区。 输出单元提供与样本中识别的目标细胞有关的数据。 还提供了一种方法。

公开(公告)号：US20130105692A1

公开(公告)日：2013-05-02

申请号：US13806342

申请日：2011-07-06

申请人： Alexandra Rink ,  David Jaffray ,  Ozzy Mermut ,  Serge Caron ,  André Croteau ,  François Roy-Moisan

发明人： Alexandra Rink ,  David Jaffray ,  Ozzy Mermut ,  Serge Caron ,  André Croteau ,  François Roy-Moisan

IPC分类号： G01T1/06

CPC分类号： G01T1/06 ,  G01T1/04 ,  G01T1/201 ,  Y10T29/49826

摘要： A fiber optic dosimeter probe for sensing radiation dose including an optical fiber having a free end and a sensitive end, a window having a sensitive side and a rear side; a radiation sensitive layer between the sensitive end of the optical fiber and a sensitive side of the window, the radiation sensitive layer being made of a material having an optical property that changes with absorbed radiation dose, an amount of the material corresponding to a predetermined sensitivity to radiation; wherein the window and the optical fiber have a near water equivalent interaction with radiation and are MR compatible.

摘要翻译： 一种用于感测辐射剂量的光纤剂量计探针，包括具有自由端和敏感端的光纤，具有敏感侧和后侧的窗口; 在光纤的敏感端和窗口的敏感侧之间的辐射敏感层，辐射敏感层由具有随吸收辐射剂量变化的光学性质的材料制成，材料的量对应于预定灵敏度 辐射; 其中窗口和光纤与辐射具有近水当量的相互作用并且是MR兼容的。

公开(公告)号：US20100317966A1

公开(公告)日：2010-12-16

申请号：US12802349

申请日：2010-06-04

申请人： Nolwenn Le Bouch ,  Ozzy Mermut

发明人： Nolwenn Le Bouch ,  Ozzy Mermut

IPC分类号： A61B5/05 ,  C07D209/20 ,  C07D487/22 ,  C01B13/00 ,  C01B21/20

CPC分类号： A61K49/0067 ,  A61K49/0021 ,  A61K49/0036

摘要： A contrast marker for use in imaging applications, wherein the marker is sensitive to an applied magnetic field through the formation of radical pair species and wherein the marker is independently magnetically sensitive, optically sensitive, and magneto-optically sensitive.

摘要翻译： 用于成像应用的对比标记，其中所述标记通过形成自由基对物种对所施加的磁场敏感，并且其中所述标记独立地是磁敏感的，光敏的和磁光敏感的。

公开(公告)号：US09000401B2

公开(公告)日：2015-04-07

申请号：US13806342

申请日：2011-07-06

申请人： Alexandra Rink ,  David Jaffray ,  Ozzy Mermut ,  Serge Caron ,  André Croteau ,  François Roy-Moisan

发明人： Alexandra Rink ,  David Jaffray ,  Ozzy Mermut ,  Serge Caron ,  André Croteau ,  François Roy-Moisan

IPC分类号： G01T1/06 ,  G01T1/20

CPC分类号： G01T1/06 ,  G01T1/04 ,  G01T1/201 ,  Y10T29/49826

摘要： A fiber optic dosimeter probe for sensing radiation dose including an optical fiber having a free end and a sensitive end, a window having a sensitive side and a rear side; a radiation sensitive layer between the sensitive end of the optical fiber and a sensitive side of the window, the radiation sensitive layer being made of a material having an optical property that changes with absorbed radiation dose, an amount of the material corresponding to a predetermined sensitivity to radiation; wherein the window and the optical fiber have a near water equivalent interaction with radiation and are MR compatible.

摘要翻译： 一种用于感测辐射剂量的光纤剂量计探针，包括具有自由端和敏感端的光纤，具有敏感侧和后侧的窗口; 在光纤的敏感端和窗口的敏感侧之间的辐射敏感层，辐射敏感层由具有随吸收辐射剂量变化的光学性质的材料制成，材料的量对应于预定灵敏度 辐射; 其中窗口和光纤与辐射具有近水当量的相互作用并且是MR兼容的。

公开(公告)号：US20120271176A1

公开(公告)日：2012-10-25

申请号：US13329557

申请日：2011-12-19

申请人： Hassan Ghaderi MOGHADDAM ,  Pascal GALLANT ,  Ozzy MERMUT ,  Israël VEILLEUX

发明人： Hassan Ghaderi MOGHADDAM ,  Pascal GALLANT ,  Ozzy MERMUT ,  Israël VEILLEUX

IPC分类号： A61B6/00

CPC分类号： A61B17/1703 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0261 ,  A61B5/14551 ,  A61B5/4542 ,  A61B5/489 ,  A61B5/4893 ,  A61B17/1673 ,  A61B2034/2057 ,  A61B2090/306 ,  A61C1/084 ,  A61C1/088 ,  A61C8/0089 ,  A61C19/04

摘要： A low coherence interferometry probe system for evaluating proximity to a tissue layer, comprising a low coherence light source, an excitation optical fiber to bring the low coherence excitation light near the tissue layer and a collection optical fiber for capturing back-scattered light from the tissue layer. The probe system comprises an interferometry sub-system and a processor for evaluating a distance to the tissue layer. There is also provided a spectral absorption probe system for evaluating proximity to an artery, comprising a light source excitation light having a wavelength adapted for absorption by blood chromophores, an excitation optical fiber and a collection optical fiber. The probe system comprises a light detector and a processor for determining a distance to the artery using the Beer-Lambert law of light absorption with a value for surrounding tissue attenuation coefficient (μeff). A probe system combining low coherence interferometry and spectral absorption is also provided.

摘要翻译： 一种低相干干涉测量系统，用于评估与组织层的接近度，包括低相干光源，激发光纤以使组织层附近的低相干激发光和用于从组织捕获反向散射光的收集光纤 层。 探针系统包括干涉测量子系统和用于评估到组织层的距离的处理器。 还提供了一种用于评估与动脉接近的光谱吸收探针系统，包括具有适于由血液发色团吸收的波长的光源激发光，激发光纤和收集光纤。 探针系统包括光检测器和处理器，用于使用具有围绕组织衰减系数（μeff）的值的光吸收的Beer-Lambert定律来确定到动脉的距离。 还提供了组合低相干干涉测量和光谱吸收的探针系统。

公开(公告)号：US09179843B2

公开(公告)日：2015-11-10

申请号：US13329557

申请日：2011-12-19

申请人： Hassan Ghaderi Moghaddam ,  Pascal Gallant ,  Ozzy Mermut ,  Israël Veilleux

发明人： Hassan Ghaderi Moghaddam ,  Pascal Gallant ,  Ozzy Mermut ,  Israël Veilleux

IPC分类号： A61B6/00 ,  A61B5/00 ,  A61C19/04 ,  A61B5/1455

CPC分类号： A61B17/1703 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0261 ,  A61B5/14551 ,  A61B5/4542 ,  A61B5/489 ,  A61B5/4893 ,  A61B17/1673 ,  A61B2034/2057 ,  A61B2090/306 ,  A61C1/084 ,  A61C1/088 ,  A61C8/0089 ,  A61C19/04

摘要： A low coherence interferometry probe system for evaluating proximity to a tissue layer, comprising a low coherence light source, an excitation optical fiber to bring the low coherence excitation light near the tissue layer and a collection optical fiber for capturing back-scattered light from the tissue layer. The probe system comprises an interferometry sub-system and a processor for evaluating a distance to the tissue layer. There is also provided a spectral absorption probe system for evaluating proximity to an artery, comprising a light source excitation light having a wavelength adapted for absorption by blood chromophores, an excitation optical fiber and a collection optical fiber. The probe system comprises a light detector and a processor for determining a distance to the artery using the Beer-Lambert law of light absorption with a value for surrounding tissue attenuation coefficient (μeff). A probe system combining low coherence interferometry and spectral absorption is also provided.

摘要翻译： 一种低相干干涉测量系统，用于评估与组织层的接近度，包括低相干光源，激发光纤以使组织层附近的低相干激发光和用于从组织捕获反向散射光的收集光纤 层。 探针系统包括干涉测量子系统和用于评估到组织层的距离的处理器。 还提供了一种用于评估与动脉接近的光谱吸收探针系统，包括具有适于由血液发色团吸收的波长的光源激发光，激发光纤和收集光纤。 探针系统包括光检测器和处理器，用于使用具有围绕组织衰减系数（μeff）的值的光吸收的Beer-Lambert定律来确定到动脉的距离。 还提供了组合低相干干涉测量和光谱吸收的探针系统。

公开(公告)号：US20100312097A1

公开(公告)日：2010-12-09

申请号：US12802363

申请日：2010-06-04

申请人： Pascal Gallant ,  Ozzy Mermut

发明人： Pascal Gallant ,  Ozzy Mermut

IPC分类号： A61B5/055

CPC分类号： A61B5/055

摘要： An apparatus for providing physiological information from an organism in disease diagnosis and treatment monitoring, for use in an MRI instrument. The apparatus operates on the concept of hybridized magneto-optical sensitivity. The MRI includes an MRI scanner and a controller for controlling the MRI scanner. The MRI scanner provides a magnetic field of at least 0.5T. The apparatus further includes a front end built of non-magnetic components, comprising light guides for illuminating a region of interest (ROI) and for collecting light emitted at said ROI; and a back-end comprising a light source for injecting light into said light guides; a light detector for receiving light collected at said ROI; and a processing and control unit for processing said light collected at said ROI.

摘要翻译： 一种用于在用于MRI仪器的疾病诊断和治疗监测中从生物体提供生理信息的装置。 该装置基于杂波磁光灵敏度的概念。 MRI包括MRI扫描器和用于控制MRI扫描仪的控制器。 MRI扫描仪提供至少0.5T的磁场。 该装置还包括由非磁性部件构成的前端，包括用于照亮感兴趣区域（ROI）的光导和用于收集在所述RO​​I处发射的光; 以及后端，其包括用于将光注入所述光导中的光源; 用于接收在所述RO​​I处收集的光的光检测器; 以及处理和控制单元，用于处理在所述RO​​I处收集的所述光。