-
1.发明授权Method for detecting binding interactions between membrane proteins and analytes in a homogenous assay 有权用于在同源测定中检测膜蛋白和分析物之间的结合相互作用的方法公开(公告)号：US08450118B2
公开(公告)日：2013-05-28
申请号：US12799689
申请日：2010-04-28
申请人： Scot Weinberger , Stephen Dotson , Nathan Harris
发明人： Scot Weinberger , Stephen Dotson , Nathan Harris
CPC分类号： G01N33/54393 , G01N21/45 , G01N33/5432 , G01N33/54373 , G01N33/92
摘要： Devices and methods for detecting interaction between components associated with lipid membranes and analytes are described herein. In certain methods, a surface of a compartment of a device is coated with a material that attaches to lipid membrane from a sample. An analyte is introduced and interaction is detected, for example, by back scattering interferometry. In another method, a surface is passivated with a material that does not bind a lipid membrane. A sample is introduced that contains a membrane comprising a component for testing and an analyte. Interaction is detected. In a third method, a channel is filled with a first liquid that does not comprise a lipid membrane. A bolus of a second liquid that comprises a membrane comprising a component for testing and an analyte is introduced under laminar flow conditions so that a leading edge of the second liquid does not completely displace the first liquid in a sensing area that is interrogated by optical methods, for example, a laser. Interaction between the analyte and the component is detected.
摘要翻译： 本文描述了用于检测与脂质膜和分析物相关的组分之间相互作用的装置和方法。 在某些方法中，装置的隔室的表面涂覆有从样品附着到脂质膜的材料。 引入分析物并检测相互作用，例如通过反向散射干涉测量。 在另一种方法中，用不结合脂质膜的材料钝化表面。 引入了包含含有用于测试的组分和分析物的膜的样品。 检测到相互作用。 在第三种方法中，通道填充有不包含脂质膜的第一液体。 在层流条件下引入包括包含用于测试的组分的膜和分析物的第二液体的推注，使得第二液体的前缘不会在通过光学方法询问的感测区域中完全置换第一液体 ，例如，激光。 检测分析物与组分之间的相互作用。
-
公开(公告)号：US09004506B2
公开(公告)日：2015-04-14
申请号：US13472316
申请日：2012-05-15
申请人： Patrick Rutz , Casey Nathan Harris
发明人： Patrick Rutz , Casey Nathan Harris
CPC分类号： A63B47/00 , A47B81/00 , A47B91/00 , A63B47/002 , A63B2225/09
摘要： A ball cart comprising a removable and rotatable ball basket having a plurality of separated chambers that are each able to hold a different kind of ball. Thus, whenever a particular type of ball is desired, a user is able to rotate the basket and lock it in place such that a lid of the chamber that holds balls of that type is accessible to the user. As a result, the user is able to easily select that type of balls desired from the ball cart without sifting through all of the balls in the ball cart.
摘要翻译： 一种球形推车，其包括具有多个分离的腔室的可拆卸且可旋转的球篮，每个腔室能够容纳不同种类的球。 因此，每当需要特定类型的球时，使用者能够旋转篮子并将其锁定在适当的位置，使得保持该类型球的腔室的盖子可被使用者接近。 结果，用户能够轻松地从球车中选择所需的类型的球，而不会筛选球车中的所有球。
-
公开(公告)号：US07204154B2
公开(公告)日：2007-04-17
申请号：US11525689
申请日：2006-09-22
申请人： Kevin Sartain , Nathan Harris , Steve Wojcik , Rick Urquhart , Mike Daniels , James Baggot
发明人： Kevin Sartain , Nathan Harris , Steve Wojcik , Rick Urquhart , Mike Daniels , James Baggot
IPC分类号： G01N3/08
CPC分类号： G01N3/08 , B65H2301/41484 , B65H2515/12 , G01N3/14 , G01N3/40 , G01N33/34 , G01N2203/0266 , G01N2203/0278 , G01N2203/0282 , B65H2220/03
摘要： An online roll firmness measurement system is disclosed. In one embodiment, a contact element is placed in a fixed position. A roll of material is placed in between the contact element and a support surface. Based upon the amount of force exerted on the contact element, the firmness of the roll of material may be measured. In an alternative embodiment, the contact element applies a predetermined amount of force on the roll of material but is displaced when a roll of material is placed in between the contact element and the support surface. In this embodiment, the amount of displacement of the contact element is measured which allows for the calculation of roll firmness. In one embodiment, a roll firmness device made in accordance with the present invention may be placed in a system for winding rolls and used to maintain rolls of material being formed within preset roll firmness ranges.
摘要翻译： 公开了一种在线卷硬测量系统。 在一个实施例中，将接触元件置于固定位置。 将一卷材料放置在接触元件和支撑表面之间。 基于施加到接触元件上的力的量，可以测量材料卷的坚固度。 在替代实施例中，接触元件在材料卷上施加预定量的力，但是当将一卷材料放置在接触元件和支撑表面之间时，其移位。 在该实施例中，测量接触元件的位移量，其允许计算辊子坚固度。 在一个实施例中，根据本发明制造的辊紧度装置可以放置在用于卷绕辊的系统中，并且用于将形成在预定辊的坚固度范围内的材料卷保持起来。
-
公开(公告)号：US20100023616A1
公开(公告)日：2010-01-28
申请号：US12322213
申请日：2009-01-30
申请人： Nathan Harris
发明人： Nathan Harris
IPC分类号： G06F15/16
CPC分类号： G06Q30/04
摘要： Disclosed are systems and methods for transmitting information from a remote location to a financial decision system. In certain representative transmission methods machine readable content is generated that is adapted to be received by a financial decision system. The machine readable content is transmitted using a first protocol or standard. The transmission of machine readable content is received and converted from the first protocol to a second protocol or standard. The machine readable content is then transmitted using the second protocol. The first protocol can be a non-packet switched serial protocol, such as RS-232. The second protocol can be a packet-switched Internet Protocol (IP), such as for example, User Datagram Protocol (UDP) or Transmission Control Protocol (TCP).
摘要翻译： 公开了用于将信息从远程位置传送到财务决策系统的系统和方法。 在某些代表性传输方法中，生成适于由财务决策系统接收的机器可读内容。 使用第一协议或标准传输机器可读内容。 机器可读内容的传输被接收并从第一协议转换成第二协议或标准。 然后使用第二协议传输机器可读内容。 第一协议可以是非分组交换串行协议，例如RS-232。 第二协议可以是分组交换因特网协议（IP），例如用户数据报协议（UDP）或传输控制协议（TCP）。
-
公开(公告)号：US20190075934A1
公开(公告)日：2019-03-14
申请号：US15701323
申请日：2017-09-11
申请人： Nathan Harris
发明人： Nathan Harris
摘要： A collapsible infant tray formed from flexible polymeric materials having two or more receptacles securing infant chattels including perishable foods. In various embodiments, the receptacles are formed by one or more L-shaped detachable members.
-
公开(公告)号：US20070012119A1
公开(公告)日：2007-01-18
申请号：US11525689
申请日：2006-09-22
申请人： Kevin Sartain , Nathan Harris , Steve Wojcik , Rick Urquhart , Mike Daniels , James Baggot
发明人： Kevin Sartain , Nathan Harris , Steve Wojcik , Rick Urquhart , Mike Daniels , James Baggot
IPC分类号： G01N3/08
CPC分类号： G01N3/08 , B65H2301/41484 , B65H2515/12 , G01N3/14 , G01N3/40 , G01N33/34 , G01N2203/0266 , G01N2203/0278 , G01N2203/0282 , B65H2220/03
摘要： An online roll firmness measurement system is disclosed. In one embodiment, a contact element is placed in a fixed position. A roll of material is placed in between the contact element and a support surface. Based upon the amount of force exerted on the contact element, the firmness of the roll of material may be measured. In an alternative embodiment, the contact element applies a predetermined amount of force on the roll of material but is displaced when a roll of material is placed in between the contact element and the support surface. In this embodiment, the amount of displacement of the contact element is measured which allows for the calculation of roll firmness. In one embodiment, a roll firmness device made in accordance with the present invention may be placed in a system for winding rolls and used to maintain rolls of material being formed within preset roll firmness ranges.
-
公开(公告)号：US20050097966A1
公开(公告)日：2005-05-12
申请号：US10704384
申请日：2003-11-07
申请人： Kevin Sartain , Nathan Harris , Steve Wojcik , Rick Urquhart , Mike Daniels , James Baggot
发明人： Kevin Sartain , Nathan Harris , Steve Wojcik , Rick Urquhart , Mike Daniels , James Baggot
CPC分类号： G01N3/08 , B65H2301/41484 , B65H2515/12 , G01N3/14 , G01N3/40 , G01N33/34 , G01N2203/0266 , G01N2203/0278 , G01N2203/0282 , B65H2220/03
摘要： An online roll firmness measurement system is disclosed. In one embodiment, a contact element is placed in a fixed position. A roll of material is placed in between the contact element and a support surface. Based upon the amount of force exerted on the contact element, the firmness of the roll of material may be measured. In an alternative embodiment, the contact element applies a predetermined amount of force on the roll of material but is displaced when a roll of material is placed in between the contact element and the support surface. In this embodiment, the amount of displacement of the contact element is measured which allows for the calculation of roll firmness. In one embodiment, a roll firmness device made in accordance with the present invention may be placed in a system for winding rolls and used to maintain rolls of material being formed within preset roll firmness ranges.
摘要翻译： 公开了一种在线卷硬测量系统。 在一个实施例中，将接触元件置于固定位置。 将一卷材料放置在接触元件和支撑表面之间。 基于施加在接触元件上的力的量，可以测量材料卷的坚固度。 在替代实施例中，接触元件在材料卷上施加预定量的力，但是当将一卷材料放置在接触元件和支撑表面之间时，其移位。 在该实施例中，测量接触元件的位移量，其允许计算辊子坚固度。 在一个实施例中，根据本发明制造的辊紧度装置可以放置在用于卷绕辊的系统中，并且用于将形成在预定辊的坚固度范围内的材料卷保持起来。
-
公开(公告)号：US09202238B2
公开(公告)日：2015-12-01
申请号：US12322213
申请日：2009-01-30
申请人： Nathan Harris
发明人： Nathan Harris
CPC分类号： G06Q30/04
摘要： Disclosed are systems and methods for transmitting information from a remote location to a financial decision system. In certain representative transmission methods machine readable content is generated that is adapted to be received by a financial decision system. The machine readable content is transmitted using a first protocol or standard. The transmission of machine readable content is received and converted from the first protocol to a second protocol or standard. The machine readable content is then transmitted using the second protocol. The first protocol can be a non-packet switched serial protocol, such as RS-232. The second protocol can be a packet-switched Internet Protocol (IP), such as for example, User Datagram Protocol (UDP) or Transmission Control Protocol (TCP).
摘要翻译： 公开了用于将信息从远程位置传送到财务决策系统的系统和方法。 在某些代表性传输方法中，生成适于由财务决策系统接收的机器可读内容。 使用第一协议或标准传输机器可读内容。 机器可读内容的传输被接收并从第一协议转换成第二协议或标准。 然后使用第二协议传输机器可读内容。 第一协议可以是非分组交换串行协议，例如RS-232。 第二协议可以是分组交换因特网协议（IP），例如用户数据报协议（UDP）或传输控制协议（TCP）。
-
公开(公告)号：US20130127317A1
公开(公告)日：2013-05-23
申请号：US13472316
申请日：2012-05-15
申请人： Patrick Rutz , Casey Nathan Harris
发明人： Patrick Rutz , Casey Nathan Harris
CPC分类号： A63B47/00 , A47B81/00 , A47B91/00 , A63B47/002 , A63B2225/09
摘要： A ball cart comprising a removable and rotatable ball basket having a plurality of separated chambers that are each able to hold a different kind of ball. Thus, whenever a particular type of ball is desired, a user is able to rotate the basket and lock it in place such that a lid of the chamber that holds balls of that type is accessible to the user. As a result, the user is able to easily select that type of balls desired from the ball cart without sifting through all of the balls in the ball cart.
摘要翻译： 一种球形推车，其包括具有多个分离的腔室的可拆卸且可旋转的球篮，每个腔室能够容纳不同种类的球。 因此，每当需要特定类型的球时，使用者能够旋转篮子并将其锁定在适当的位置，使得保持该类型球的腔室的盖子可被使用者接近。 结果，用户能够轻松地从球车中选择所需的类型的球，而不会筛选球车中的所有球。
-
公开(公告)号：US20100291700A1
公开(公告)日：2010-11-18
申请号：US12799689
申请日：2010-04-28
申请人： Scot Weinberger , Stephen Dotson , Nathan Harris
发明人： Scot Weinberger , Stephen Dotson , Nathan Harris
CPC分类号： G01N33/54393 , G01N21/45 , G01N33/5432 , G01N33/54373 , G01N33/92
摘要： Devices and methods for detecting interaction between components associated with lipid membranes and analytes are described herein. In certain methods, a surface of a compartment of a device is coated with a material that attaches to lipid membrane from a sample. An analyte is introduced and interaction is detected, for example, by back scattering interferometry. In another method, a surface is passivated with a material that does not bind a lipid membrane. A sample is introduced that contains a membrane comprising a component for testing and an analyte. Interaction is detected. In a third method, a channel is filled with a first liquid that does not comprise a lipid membrane. A bolus of a second liquid that comprises a membrane comprising a component for testing and an analyte is introduced under laminar flow conditions so that a leading edge of the second liquid does not completely displace the first liquid in a sensing area that is interrogated by optical methods, for example, a laser. Interaction between the analyte and the component is detected.
摘要翻译： 本文描述了用于检测与脂质膜和分析物相关的组分之间相互作用的装置和方法。 在某些方法中，装置的隔室的表面涂覆有从样品附着到脂质膜的材料。 引入分析物并检测相互作用，例如通过反向散射干涉测量。 在另一种方法中，用不结合脂质膜的材料钝化表面。 引入了包含含有用于测试的组分和分析物的膜的样品。 检测到相互作用。 在第三种方法中，通道填充有不包含脂质膜的第一液体。 在层流条件下引入包括包含用于测试的组分的膜和分析物的第二液体的推注，使得第二液体的前缘不会在通过光学方法询问的感测区域中完全置换第一液体 ，例如，激光。 检测分析物与组分之间的相互作用。
-
-
-
-
-
-
-
-
-
搜索结果
13 条记录 (耗时 0.015 秒)
