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1.
公开(公告)号:US20240059798A1
公开(公告)日:2024-02-22
申请号:US18069529
申请日:2022-12-21
Applicant: ModeX Therapeutics, Inc.
Inventor: LING XU , LAN WU , EDWARD SEUNG , ZHI-YONG YANG , GARY J. NABEL , ELIAS ZERHOUNI , RONNIE R. WEI , HAO CHEN , MARK GRECI , NICHOLAS JONES
CPC classification number: C07K16/468 , A61P35/00 , C07K2317/524 , C07K2317/526 , C07K2317/522 , C07K2317/31 , C07K2317/565
Abstract: Disclosed are antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptide complexes; cells, pharmaceutical compositions, and kits containing such polypeptide complexes; and methods of using such polypeptide complexes.
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2.
公开(公告)号:US20240109955A1
公开(公告)日:2024-04-04
申请号:US18345478
申请日:2023-06-30
Applicant: ModeX Therapeutics, Inc. , The United States of America, As Represented by the Secretary, Dept. of Health and Human Services
Inventor: Juan LI , Chi-Jen WEI , Ronnie R. WEI , Zhi-Yong YANG , John R. MASCOLA , Gary J. NABEL , John MISASI , Amarendra PEGU , Lingshu WANG , Tongqing ZHOU , Misook CHOE , Olamide K. OLONINIYI , Bingchun ZHAO , Yi ZHANG , Eun Sung YANG , Man CHEN , Kwanyee LEUNG , Wei SHI , Nancy J. SULLIVAN , Peter D. KWONG , Richard A. KOUP , Barney S. GRAHAM , Peng HE
IPC: C07K16/10 , A61P31/14 , G01N33/569
CPC classification number: C07K16/1003 , A61P31/14 , G01N33/56983 , C07K2317/24 , C07K2317/31 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/92
Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural and/or functional features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.
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3.
公开(公告)号:US20240034808A1
公开(公告)日:2024-02-01
申请号:US18067230
申请日:2022-12-16
Applicant: ModeX Therapeutics, Inc.
Inventor: HEATHER DAWN KAMP , EDWARD SEUNG , ZHI-YONG YANG , GARY J. NABEL , RONNIE R. WEI , ELIAS ZERHOUNI
IPC: C07K16/32 , C07K14/525 , C07K16/28 , A61P35/00
CPC classification number: C07K16/32 , C07K14/525 , C07K16/2818 , C07K16/2809 , A61P35/00 , C07K2317/31 , A61K38/00
Abstract: Disclosed are antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptide complexes; cells, pharmaceutical compositions, and kits containing such polypeptide complexes; and methods of using such polypeptide complexes.
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4.
公开(公告)号:US20230203199A1
公开(公告)日:2023-06-29
申请号:US17936041
申请日:2022-09-28
Applicant: ModeX Therapeutics
Inventor: Ronnie Rong WEI , Ling XU , Zhi-Yong YANG , Edward SEUNG , Gary J. NABEL , Lan WU , Mark GRECI , Hao CHEN
CPC classification number: C07K16/468 , A61P35/00 , C07K2317/31 , C07K2317/73 , C07K2317/92
Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells, chimeric antigen receptors (CARs), immune cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.
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5.
公开(公告)号:US20230235092A1
公开(公告)日:2023-07-27
申请号:US17936044
申请日:2022-09-28
Applicant: ModeX Therapeutics
Inventor: Ronnie Rong WEI , Ling XU , Zhi-Yong YANG , Edward SEUNG , Gary J. NABEL , Lan WU , Mark GRECI , Hao CHEN
CPC classification number: C07K19/00 , C07K16/1018 , C07K16/1027 , C07K16/087 , C07K16/082 , C07K16/1081 , C07K16/1275 , C07K16/125 , C07K16/1285 , C07K16/1253 , C07K16/1009 , C07K2319/41 , C07K2319/43 , C07K2319/42 , C07K2317/21 , C07K2317/24
Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; chimeric antigen receptors (CARs), cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.
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6.
公开(公告)号:US20230227553A1
公开(公告)日:2023-07-20
申请号:US17936047
申请日:2022-09-28
Applicant: ModeX Therapeutics
Inventor: Ronnie Rong WEI , Ling XU , Zhi-Yong YANG , Edward SEUNG , Gary J. NABEL
CPC classification number: C07K16/2809 , C07K16/2803 , C07K16/2887 , C07K16/2818 , C07K16/2878 , C07K16/2866 , A61P35/00 , C07K16/3076 , C07K16/1063 , A61P31/12 , C07K2317/31
Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells; chimeric antigen receptors (CARs); immune cells; pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.
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