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1.
公开(公告)号:US20230235092A1
公开(公告)日:2023-07-27
申请号:US17936044
申请日:2022-09-28
Applicant: ModeX Therapeutics
Inventor: Ronnie Rong WEI , Ling XU , Zhi-Yong YANG , Edward SEUNG , Gary J. NABEL , Lan WU , Mark GRECI , Hao CHEN
CPC classification number: C07K19/00 , C07K16/1018 , C07K16/1027 , C07K16/087 , C07K16/082 , C07K16/1081 , C07K16/1275 , C07K16/125 , C07K16/1285 , C07K16/1253 , C07K16/1009 , C07K2319/41 , C07K2319/43 , C07K2319/42 , C07K2317/21 , C07K2317/24
Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; chimeric antigen receptors (CARs), cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.
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2.
公开(公告)号:US20230203199A1
公开(公告)日:2023-06-29
申请号:US17936041
申请日:2022-09-28
Applicant: ModeX Therapeutics
Inventor: Ronnie Rong WEI , Ling XU , Zhi-Yong YANG , Edward SEUNG , Gary J. NABEL , Lan WU , Mark GRECI , Hao CHEN
CPC classification number: C07K16/468 , A61P35/00 , C07K2317/31 , C07K2317/73 , C07K2317/92
Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells, chimeric antigen receptors (CARs), immune cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.