公开(公告)号：US08448881B2

公开(公告)日：2013-05-28

申请号：US11974392

申请日：2007-10-12

申请人： Kenneth James Young ,  Yann Courbariaux ,  Michel Houde ,  Daniel Haggerty ,  Philip Buelow

发明人： Kenneth James Young ,  Yann Courbariaux ,  Michel Houde ,  Daniel Haggerty ,  Philip Buelow

IPC分类号： B05B1/34 ,  B05B1/26 ,  F02K9/28 ,  F02G3/00

CPC分类号： F02M61/163 ,  F02M2200/06

摘要： An apparatus and method for minimizing and/or preventing thermal degradation of fuel in a fuel injector is disclosed. The body of the injector includes a fuel gallery with a contoured scarf formed therein. The scarf is configured to minimize and/or prevent fuel recirculation thus reducing the likelihood that fuel will dwell in an area long enough to sufficient to cause the degradation of the fuel.

摘要翻译： 公开了一种用于最小化和/或防止燃料喷射器中的燃料热降解的装置和方法。 喷射器的主体包括在其中形成有轮廓的围巾的燃料镜。 围巾被配置为使燃料再循环最小化和/或防止燃料循环，从而降低燃料将停留在足以引起燃料劣化的区域的可能性。

公开(公告)号：US20110306055A1

公开(公告)日：2011-12-15

申请号：US12935201

申请日：2010-02-24

申请人： Jean-Francois Haince ,  Guillaume Beaudry ,  Genevieve Garon ,  Michel Houde ,  Timothy J. Holzer ,  Martin Beaulieu ,  Nicolas Bertrand

发明人： Jean-Francois Haince ,  Guillaume Beaudry ,  Genevieve Garon ,  Michel Houde ,  Timothy J. Holzer ,  Martin Beaulieu ,  Nicolas Bertrand

IPC分类号： C12Q1/68

CPC分类号： G01N33/57419 ,  C12Q1/34 ,  C12Q1/527 ,  G01N33/573 ,  G01N2800/52

摘要： The present invention provides a novel method for diagnosing, monitoring, prognosing and staging Lymph Node (LN) status in colorectal cancer (CRC) that is more sensitive and accurate than conventional detection technologies such as histopathology. The Guanylyl Cyclase C (GCC) gene is specifically expressed in apical epithelial cells of the GI tract from the duodenum to the rectum and the detection of GCC mRNA in LNs is indicative of the presence of metastases. Quantitative RT-PCR (RT-qPCR) detection of GCC mRNA to identify the presence of colorectal cancer (CRC) cells in LNs has the potential to aid in CRC staging. When used in combination with glucuronidase B (GUSB), accurate quantification of GCC can be achieved with less than a 2-fold variation between intact and highly degraded RNA specimens. The invention also relates to a newly designed GCC/GUSB assay that uses relative quantification having improved prognostic value for time to recurrence and relapse-free survival in Stage I or II colon cancer patients. The GCC/GUSB assay also improves the statistical power of prognosis stratification for relative risk of recurrence and relapse-free survival.

摘要翻译： 本发明提供了一种用于诊断，监测，预后和分期结直肠癌（CRC）中的淋巴结（LN）状态的新方法，其比常规检测技术如组织病理学更灵敏和准确。 Guanylyl Cyclase C（GCC）基因在十二指肠至直肠胃肠道的顶端上皮细胞中特异性表达，LN检测GCC mRNA表示存在转移灶。 定量RT-PCR（RT-qPCR）检测GCC mRNA以鉴定LN中结肠直肠癌（CRC）细胞的存在有助于CRC分期。 当与葡糖醛酸糖苷酶B（GUSB）组合使用时，可以在完整和高度降解的RNA标本之间以小于2倍的变化实现GCC的准确定量。 本发明还涉及一种新设计的GCC / GUSB测定法，其使用相对定量，其具有改善I期或II期结肠癌患者的复发和无复发存活时间的预后价值。 GCC / GUSB测定还提高了复发和无复发生存相对风险的预后分层的统计学功能。

公开(公告)号：US06567656B1

公开(公告)日：2003-05-20

申请号：US09666897

申请日：2000-09-20

申请人： Patrice Varinot ,  Michel Houde

发明人： Patrice Varinot ,  Michel Houde

IPC分类号： H04M1500

CPC分类号： H04W12/02 ,  H04L63/304 ,  H04M15/00 ,  H04M15/47 ,  H04M15/58 ,  H04M15/8083 ,  H04M2215/0148 ,  H04M2215/0184 ,  H04M2215/0188 ,  H04M2215/32 ,  H04W24/00 ,  H04W36/12 ,  H04W76/10

摘要： Control is exercised over a tap connection made for law enforcement agency monitoring of mobile station communications in response to an inter-exchange hand-off. Where such a tap connection does not yet exist at hand-off, pre-hand-off actions taken at the target exchange trigger an analysis of whether a party to that communication is marked for monitoring followed by an establishment of the tap connection at hand-off if the party is so marked. If the tap connection is already in place, pre-hand-off actions taken at the target exchange trigger an analysis of whether law enforcement agency monitoring of that communication is lawfully authorized with respect to the target exchange followed by instructing the anchor exchange to terminate the tap connection at hand-off if monitoring is not lawfully authorized.

摘要翻译： 通过针对移动电台通信的执法机构监控的接口进行控制，以响应交换间切换。 在这种抽头连接尚未存在切换的情况下，在目标交换机上采取的切换前的动作触发对该通信方是否被标记为进行监控的分析，然后在手头建立分接连接， 如果派对是如此标记的话。 如果分支连接已经到位，目标交易所采取的预先切换行为会引发对执行机构对该通信的监控是否合法授权对目标交换进行分析，然后指示主机交换终止 如果监控没有合法授权，则切换连接。

公开(公告)号：US06195547B1

公开(公告)日：2001-02-27

申请号：US09160369

申请日：1998-09-24

申请人： Michel Corriveau ,  Michel Houde

发明人： Michel Corriveau ,  Michel Houde

IPC分类号： H04M300

CPC分类号： H04W8/265 ,  H04W12/06

摘要： There is disclosed a system and method for over the air (OTA) activation of a previously activated mobile station in a wireless telecommunications network. During the new activation, an over the air processor requests the data configuration of the mobile station. The mobile station may issue a first challenge to the over the air processor and in so doing transmits a challenge message including certain mobile station parameters to the over the air processor. The over the air processor then communicates this information to the network authentication center which produces a challenge return message from the certain mobile station parameters and sends the challenge return message to the mobile station. The mobile station validates the challenge return message and if validation is successful the mobile station completes the transfer of mobile station data configuration to the over the air processor. The authentication center uses one of the Shared Secret Data Challenge (SSD_C) and Shared Secret Data Subsidy (SSD_S) security locks not broadcast over the air in the generation of the challenge return message. The authentication center stores the SSD_C and SSD_S for this purpose and is advised by the mobile station on which one of these two parameters is to be used by a Shared Secret Data Select parameter indicator (SSD_Select) forwarded by the mobile station as one of the parameters transmitted in the challenge request. The over the air processor then forwards new operating parameters to the mobile station and requests the mobile station to commit to these parameters. The mobile station may then issue a second challenge to the over the air processor request to commit where the second challenge is handled by the network in a manner similar to the first challenge.

摘要翻译： 公开了一种用于无线电信网络中先前激活的移动台的空中（OTA）激活的系统和方法。 在新的激活期间，空中处理器请求移动台的数据配置。 移动台可以向空中处理器发出第一个挑战，并且这样做将包括某些移动站参数的质询消息传送到空中处理器。 然后，空中处理器将该信息传送到网络认证中心，网络认证中心从特定的移动台参数产生询问返回消息，并向移动台发送质询返回消息。 移动台验证挑战返回消息，如果验证成功，则移动台完成移动台数据配置到空中处理器的传输。 身份验证中心使用共享秘密数据挑战（SSD_C）和共享秘密数据补贴（SSD_S）之间的安全锁，而这些安全锁在生成挑战返回消息时无法广播。 认证中心为此存储SSD_C和SSD_S，并由移动台通过由移动台转发的共享秘密数据选择参数指示符（SSD_Select）将使用这两个参数中的哪一个作为参数之一的移动台 在挑战请求中传送。 然后空中处理器将新的操作参数转发到移动台，并请求移动台承诺这些参数。 然后，移动台可以以空中处理器请求发出第二个挑战，以便以类似于第一挑战的方式由网络处理第二挑战。

公开(公告)号：US6128481A

公开(公告)日：2000-10-03

申请号：US956085

申请日：1997-10-22

申请人： Michel Houde ,  Gustavo Pavon

发明人： Michel Houde ,  Gustavo Pavon

IPC分类号： H04W4/22 ,  G01S1/08 ,  H04B7/15 ,  H04B1/00 ,  H04M11/00

CPC分类号： H04W4/22 ,  H04W76/007

摘要： A system and method for routing an emergency services call from a mobile station to a selected Public Safety Answering Point (PSAP) in a radio telecommunications network. The system intelligently selects the PSAP from a plurality of PSAPs, warns the selected PSAP that the emergency services call is coming prior to routing the call to the selected PSAP, and provides the selected PSAP with advanced information regarding the context of the call. The emergency services call is received by a serving mobile switching center (MSC) which determines that the call is an emergency services call and sends cell or sector information to a service control point (SCP). The SCP includes a PSAP selector which selects the PSAP based on such information as, for example, the location of the mobile station, the Local Access and Traffic Area (LATA) in which the mobile station is located, the time-of-day, and the day-of-week. The SCP then sends an alerting signal to the selected PSAP and includes a tag and information relating to the context of the call. The SCP then returns the tag and the identity of the selected PSAP to the serving MSC which determines the PSAP routing number and delivers the call to the selected PSAP.

摘要翻译： 一种用于将紧急服务呼叫从移动台路由到无线电电信网络中的选定的公共安全应答点（PSAP）的系统和方法。 该系统从多个PSAP智能地选择PSAP，警告所选择的PSAP紧急服务呼叫在将呼叫路由到所选择的PSAP之前进行，并且向选定的PSAP提供关于呼叫上下文的高级信息。 紧急服务呼叫由服务移动交换中心（MSC）接收，其确定呼叫是紧急服务呼叫，并将小区或扇区信息发送到服务控制点（SCP）。 SCP包括PSAP选择器，其基于诸如移动站的位置，移动站所在的本地接入和业务区域（LATA）的时间，时间等信息来选择PSAP， 和星期几。 SCP然后向所选择的PSAP发送警报信号，并包括一个标签和与呼叫上下文有关的信息。 SCP然后将所选择的PSAP的标签和标识返回给确定PSAP路由号码的服务MSC，并将该呼叫传送到所选择的PSAP。

公开(公告)号：US20110272122A1

公开(公告)日：2011-11-10

申请号：US12773606

申请日：2010-05-04

申请人： Antoine Corbeil ,  Gregoire Berube ,  Michel Houde ,  Eric Matte

发明人： Antoine Corbeil ,  Gregoire Berube ,  Michel Houde ,  Eric Matte

IPC分类号： F28F13/18 ,  F04D29/54 ,  F28F7/00 ,  B21D53/02 ,  B23P25/00

CPC分类号： F28D1/03 ,  B22F3/002 ,  B22F2998/10 ,  B33Y80/00 ,  C23C4/00 ,  C23C30/00 ,  F28F7/00 ,  F28F13/003 ,  F28F21/089 ,  F28F2255/00 ,  F28F2255/18 ,  Y10T29/4935 ,  Y10T29/49885 ,  C23C4/12

摘要： A heat exchanger component is made by forming a wafer having a pair of opposed outer major faces with interstices between them from a stack of wire mesh screens. The outer major surfaces of the wafer are sealed by depositing a metal coating on them. The deposited metal coatings define between them a flow path for a heat exchange fluid extending through the interstices of the wafer.

摘要翻译： 热交换器部件是通过从一叠丝网筛网形成具有一对相对的外主面与它们之间的间隙的晶片制成的。 通过在其上沉积金属涂层来密封晶片的外主表面。 沉积的金属涂层在它们之间限定了延伸穿过晶片间隙的热交换流体的流路。

公开(公告)号：US20080210782A1

公开(公告)日：2008-09-04

申请号：US11974392

申请日：2007-10-12

申请人： Kenneth James Young ,  Yann Courbariaux ,  Michel Houde ,  Daniel Haggerty ,  Philip Buelow

发明人： Kenneth James Young ,  Yann Courbariaux ,  Michel Houde ,  Daniel Haggerty ,  Philip Buelow

IPC分类号： B05B7/10

CPC分类号： F02M61/163 ,  F02M2200/06

摘要： An apparatus and method for minimizing and/or preventing thermal degradation of fuel in a fuel injector is disclosed. The body of the injector includes a fuel gallery with a contoured scarf formed therein. The scarf is configured to minimize and/or prevent fuel recirculation thus reducing the likelihood that fuel will dwell in an area long enough to sufficient to cause the degradation of the fuel.

摘要翻译： 公开了一种用于最小化和/或防止燃料喷射器中的燃料热降解的装置和方法。 喷射器的主体包括在其中形成有轮廓的围巾的燃料镜。 围巾被配置为使燃料再循环最小化和/或防止燃料循环，从而降低燃料将停留在足以引起燃料劣化的区域的可能性。

公开(公告)号：US06594492B2

公开(公告)日：2003-07-15

申请号：US09316319

申请日：1999-05-21

申请人： Felix Choi ,  Michel Houde ,  Sorin Surdila

发明人： Felix Choi ,  Michel Houde ,  Sorin Surdila

IPC分类号： H04Q720

CPC分类号： H04W36/12

摘要： In the context of a completed inter-exchange handoff of a mobile station communication, an anchor exchange may request certain call related information from a currently serving exchange. This request is made through use of an inter-exchange information request message issued from the anchor exchange and sent (perhaps through one or more tandem exchanges) to the serving exchange. Responsive thereto, the serving exchange processes the request, obtains the requested call related information, and returns the requested information in an inter-exchange information request return result message. The information request message may comprise a newly defined ANSI-41 message, a vendor proprietary extension to the ANSI-41 message set, or an enhancement to an existing ANSI-41 message.

摘要翻译： 在完成的移动台通信的交换间切换的上下文中，锚交换机可以从当前的服务交换机请求某些呼叫相关信息。 该请求是通过使用从锚交换机发出并发送（可能通过一个或多个串联交换机）发送到服务交换机的交换机间信息请求消息进行的。 响应于此，服务交换机处理请求，获得所请求的呼叫相关信息，并且在交换间信息请求返回结果消息中返回所请求的信息。 信息请求消息可以包括新定义的ANSI-41消息，对ANSI-41消息集合的供应商专有扩展或对现有ANSI-41消息的增强。

公开(公告)号：US6038449A

公开(公告)日：2000-03-14

申请号：US956303

申请日：1997-10-22

申请人： Michel Corriveau ,  Michel Houde

发明人： Michel Corriveau ,  Michel Houde

IPC分类号： H04W36/12 ,  H04Q7/00

CPC分类号： H04W36/12

摘要： A cellular telephone network includes plural areas each having a plurality of cells. The cells individually supporting certain service capabilities. Inter-exchange messaging is provided for distributing from a second exchange to a first exchange information on the service capabilities supported by a cell serviced by the second exchange. Using the distributed service capability information, the first exchange may identify, in the context of a potential inter-exchange hand-off, whether to request that cells serviced by the second exchange be instructed to make verification signal strength measurements. Furthermore, responsive to received verification signal strength measurement reports, the first exchange screens candidate cells based on the distributed service capability information to select an appropriate target cell served by the second exchange for hand-off.

摘要翻译： 蜂窝电话网络包括多个区域，每个区域具有多个小区。 这些单元分别支持某些服务能力。 提供交互间消息传送用于从第二交换机向第一交换机分发关于由第二交换机服务的小区支持的服务能力的信息。 使用分布式服务能力信息，第一交换机可以在可能的交换间切换的上下文中识别是否请求指示由第二交换机服务的小区进行验证信号强度测量。 此外，响应于接收到的验证信号强度测量报告，第一次交换屏幕候选小区基于分布式服务能力信息来选择由第二交换机服务的适当的目标小区进行切换。

公开(公告)号：US6032043A

公开(公告)日：2000-02-29

申请号：US861178

申请日：1997-05-21

申请人： Michel Houde

发明人： Michel Houde

IPC分类号： H04M3/42 ,  H04M3/00 ,  H04Q7/24 ,  H04Q7/38 ,  H04M11/00

CPC分类号： H04Q3/0041

摘要： Feature dispatching within a wireless intelligent network is provided by routing feature request messages to a service control point. For example, such routing is made to bypass transmission to a home location register for the mobile station. Alternatively, such routing is made by the home location register to dispatch requests relating to service features provisioned to other nodes. Still further, dispatching of requests to the home location register is made by the service control point for feature request message implicating certain service features.Feature arbitration within a wireless intelligent network is provided by involving a service control point in call set up and delivery. In a first instance, a request message for a routing/roaming number is sent by the home location register through the service control point. In another instance, the home location register queries the service control point as to whether a service feature is implicated by the call set up and delivery. For each case, the service control point provides appropriate instructions to the home location register for handling of the call.

摘要翻译： 无线智能网内的功能调度由路由特征请求消息提供给业务控制点。 例如，这样的路由被做成绕过用于移动台的归属位置寄存器的传输。 或者，这样的路由由归属位置寄存器进行以调度与提供给其他节点的服务特征有关的请求。 此外，由服务控制点对涉及特定服务特征的特征请求消息进行向归属位置寄存器的请求的调度。 通过在呼叫建立和传送中涉及服务控制点来提供无线智能网络内的特征仲裁。 在第一种情况下，用于路由/漫游号码的请求消息由归属位置寄存器通过业务控制点发送。 在另一种情况下，归属位置寄存器查询服务控制点，以确定服务特征是由呼叫建立和传递牵连的。 对于每种情况，服务控制点向归属位置寄存器提供适当的指令以处理呼叫。