公开(公告)号：US09309479B2

公开(公告)日：2016-04-12

申请号：US14126470

申请日：2012-05-25

Applicant: Martin Schweigkofler ,  Martin Schmidt-Amelunxen

Inventor： Martin Schweigkofler ,  Martin Schmidt-Amelunxen

IPC: C10M107/38 ,  C10M113/12 ,  C10M125/26 ,  C10M131/10 ,  C10M169/02 ,  C10M105/50 ,  C10M129/26

CPC classification number: C10M131/10 ,  C10M105/50 ,  C10M113/12 ,  C10M125/26 ,  C10M129/26 ,  C10M169/02 ,  C10M2201/1056 ,  C10M2213/0606 ,  C10M2213/0626 ,  C10N2230/76 ,  C10N2240/02 ,  C10N2240/202 ,  C10N2250/10

Abstract: A lubricating grease is provided that comprises 90 to 99.45 percent by mass of perfluoropolyethers (PFPE) and 0.5 to 5 percent by mass of fumed silica.

Abstract translation: 提供了含有90〜99.45质量％的全氟聚醚（PFPE）和0.5〜5质量％的热解法二氧化硅的润滑脂。

公开(公告)号：US09198761B2

公开(公告)日：2015-12-01

申请号：US14006269

申请日：2012-03-21

Applicant: Christian Gugler ,  Martin Schmidt ,  Andreas Meyenhofer

Inventor： Christian Gugler ,  Martin Schmidt ,  Andreas Meyenhofer

IPC: A61F2/32 ,  A61F2/34 ,  A61F2/30

CPC classification number: A61F2/34 ,  A61F2/30771 ,  A61F2002/30322 ,  A61F2002/30825 ,  A61F2002/3083 ,  A61F2002/30843 ,  A61F2002/30904

Abstract: The invention relates to a ball-and-socket implant (I), in particular an acetabular implant, preferably in the shape of a spherical cup shell, said implant having at least one region with a surface structure (2, 7). The at least one region extends between the equator and the pole of the spherical cup shell. The surface structure comprises a plurality of structural elements (6), each of which is formed by a plurality of intersecting ridges (3, 8) with opposite inclinations. The number of structural elements (6) on the equator (5) or on a circle of latitude near the equator is the same as on a circle of latitude near the pole. The ridges (3, 8) have a curvature such that the inclination of the ridges with respect to the circles of latitude, and thus an angle between a tangent of the ridge curvature and a circle of latitude, continuously increases from the equator (5) to the pole (4).

Abstract translation: 本发明涉及一种球窝植入物（I），特别是髋臼植入物，优选地为球形杯壳的形状，所述植入物具有至少一个具有表面结构的区域（2,7）。 该至少一个区域在赤道与球形杯壳的极之间延伸。 表面结构包括多个结构元件（6），每个结构元件（6）由具有相反倾斜度的多个相交的脊（3,8）形成。 在赤道（5）或赤道附近的一个纬线上的结构元素（6）的数量与靠近极点的纬度圆相同。 脊（3,8）具有曲率，使得脊相对于纬线的倾斜度以及因此脊曲率的切线与纬度之间的角度从赤道（5）连续增加， 到杆（4）。

公开(公告)号：US08962803B2

公开(公告)日：2015-02-24

申请号：US12389927

申请日：2009-02-20

Applicant: Bernhard K. Mueller ,  Martin Schmidt ,  Eve Barlow ,  Mary Leddy ,  Chung-Ming Hsieh ,  Philip Bardwell

Inventor： Bernhard K. Mueller ,  Martin Schmidt ,  Eve Barlow ,  Mary Leddy ,  Chung-Ming Hsieh ,  Philip Bardwell

IPC: C07K16/00

CPC classification number: C07K16/22 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/28 ,  C07K2317/24 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92 ,  Y02A50/466

Abstract: The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind and neutralize RGM A protein. Specifically, these antibodies have the ability to inhibit the binding of RGM A to its receptor and/or coreceptors. These antibodies or portions thereof of the invention are useful for detecting RGM A and for inhibiting RGM A activity, for example in a human suffering from a disorder including but nor limited to multiple sclerosis, mammalian brain trauma, spinal cord injury, stroke, neurodegenerative diseases, and schizophrenia.

Abstract translation: 本发明涉及结合并中和RGM A蛋白的分离的蛋白质，特别是单克隆抗体。 具体地说，这些抗体具有抑制RGM A与其受体和/或共受体结合的能力。 本发明的这些抗体或其部分可用于检测RGM A和抑制RGM A活性，例如在患有包括但不限于多发性硬化，哺乳动物脑外伤，脊髓损伤，中风，神经变性疾病 和精神分裂症。

公开(公告)号：US20140155306A1

公开(公告)日：2014-06-05

申请号：US14126470

申请日：2012-05-25

Applicant: Martin Schweigkofler ,  Martin Schmidt-Amelunxen

Inventor： Martin Schweigkofler ,  Martin Schmidt-Amelunxen

IPC: C10M131/10 ,  C10M129/26 ,  C10M125/26 ,  C10M105/50

CPC classification number: C10M131/10 ,  C10M105/50 ,  C10M113/12 ,  C10M125/26 ,  C10M129/26 ,  C10M169/02 ,  C10M2201/1056 ,  C10M2213/0606 ,  C10M2213/0626 ,  C10N2230/76 ,  C10N2240/02 ,  C10N2240/202 ,  C10N2250/10

Abstract: A lubricating grease is provided that comprises 90 to 99.45 percent by mass of perfluoropolyethers (PFPE) and 0.5 to 5 percent by mass of fumed silica.

Abstract translation: 提供了含有90〜99.45质量％的全氟聚醚（PFPE）和0.5〜5质量％的热解法二氧化硅的润滑脂。

公开(公告)号：US08684413B2

公开(公告)日：2014-04-01

申请号：US13643125

申请日：2011-03-03

Applicant: Thomas Schmidt ,  Martin Schmidt ,  Christian Fischer ,  Michael Pech ,  Matthias Steinberg ,  Tobias Voss

Inventor： Thomas Schmidt ,  Martin Schmidt ,  Christian Fischer ,  Michael Pech ,  Matthias Steinberg ,  Tobias Voss

IPC: B60R22/405

CPC classification number: B60R22/4628 ,  B60R2022/4642 ,  B60R2022/4661

Abstract: A pretensioning device (10) for a safety belt, of a motor vehicle, having a gas generator (17), a piston (21) guided in a tube (16), which closes a pressure area (20) in the tube (16) that is pressurized by the gas generator (17) whereupon the piston (21) is able to move in a pretensioning movement which is able to be conveyed to the safety belt by means of an inertia body (19a) resting on a front face (9) of the piston (21). The piston (21) forms a pass-through opening (1) releasable upon exceeding of a predetermined pressure and a recess (26) is provided in the front face (9) with an inertia body (19a) resting thereon, so that a flow connection is created from the pass-through opening (1) to the area (25) located behind the piston (21) in the direction of the pretensioning movement (S).

Abstract translation: 一种用于机动车辆的安全带的预张紧装置（10），具有气体发生器（17），在管（16）中引导的活塞（21），其封闭管（16）中的压力区域（20） ），由气体发生器（17）加压，于是活塞（21）能够通过借助于静止在正面上的惯性体（19a）被传送到安全带的预张紧运动中移动 9）。 活塞（21）形成可以超过预定压力而可释放的通过开口（1），并且在前表面（9）上设置有一个在其上放置有惯性体（19a）的凹部（26） 在预张紧运动（S）的方向上从穿通开口（1）到位于活塞（21）后面的区域（25）形成连接。

公开(公告)号：US08595041B2

公开(公告)日：2013-11-26

申请号：US11348637

申请日：2006-02-07

Applicant: Martin Schmidt

Inventor： Martin Schmidt

IPC: G06Q10/00

CPC classification number: G06Q10/06 ,  G06Q10/0631 ,  G06Q10/06311 ,  G06Q10/06316

Abstract: Some embodiments of a task responsibility system may be implemented as an application to support people, machines, or both functioning in a manufacturing or production environment, warehouse environment, or other work environment. The focus is on a plant-local solution. In such circumstances, the task responsibility system may identify and direct one or more tasks to a computer-implemented folder independent of the worker(s), machine(s), or a combination thereof assigned to the folder. Thus, the system (or a user of the system) is permitted to dynamically assign a worker or machine to the computer-implemented folder subsequent to the tasks being directed thereto, in which case the worker or machine may be responsible for the tasks that are directed to the folder.

Abstract translation: 可以将任务责任系统的一些实施例实现为支持在制造或生产环境，仓库环境或其他工作环境中运行的人员，机器或二者的应用。 重点是植物本地解决方案。 在这种情况下，任务责任系统可以将一个或多个任务识别并指向独立于分配给该文件夹的工作者，机器或其组合的计算机实现的文件夹。 因此，允许系统（或系统的用户）在任务被指向之后动态地将工作者或机器分配给计算机实现的文件夹，在这种情况下，工作人员或机器可能负责任务 指向文件夹。

公开(公告)号：US20130263417A1

公开(公告)日：2013-10-10

申请号：US13994317

申请日：2011-12-22

Applicant: Martin Schmidt ,  Peter Lutze

Inventor： Martin Schmidt ,  Peter Lutze

IPC: B23P13/00

CPC classification number: B23P13/00 ,  B25B7/12 ,  B25B7/126 ,  B25B27/146 ,  H01R43/0428 ,  Y10T29/53996

Abstract: The invention relates to tools (1), such as crimping tools, comprising an acting part (31), for moving a movable tool (7) relative to a stationary tool (6) for example, wherein furthermore the acting part (31) can be moved in a motorized manner. In order to specify such tools in an advantageous embodiment, a longitudinal axis (L) of an electric motor (9) provided in order to drive the acting part (31) extends below the acting part (31) when the motor is horizontally oriented.

Abstract translation: 本发明涉及诸如压接工具的工具（1），其包括用于例如相对于固定工具（6）移动可移动工具（7）的作用部分（31），此外，作用部分（31）可以 以机动化的方式移动。 为了在有利的实施例中指定这种工具，当电动机水平定向时，设置用于驱动作用部分（31）的电动机（9）的纵向轴线（L）在作用部分（31）的下方延伸。

公开(公告)号：US20130203279A1

公开(公告)日：2013-08-08

申请号：US13879108

申请日：2011-06-20

Applicant: Martin Schmidt ,  Nicole Spilker

Inventor： Martin Schmidt ,  Nicole Spilker

IPC: H01R13/639

CPC classification number: H01R13/639 ,  H01R13/6275 ,  H02G3/081

Abstract: The invention concerns a locking device for a multi-part plug connector housing (1) comprising a housing upper portion (20) and a housing lower portion (10) fitting thereto, wherein the housing upper portion (20) and the housing lower portion (10) can be reversibly mechanically connected together by way of a spring plate (30), wherein the spring plate (30) is arranged in the interior of the housing upper portion (20) and/or of the housing lower portion (10), wherein the spring plate (30) is operatively connected to a single, outwardly disposed actuating knob (40).

Abstract translation: 本发明涉及一种用于多部分插头连接器壳体（1）的锁定装置，其包括壳体上部（20）和与其配合的壳体下部（10），其中壳体上部（20）和壳体下部 10）可以通过弹簧板（30）可逆地机械连接在一起，其中弹簧板（30）布置在壳体上部（20）和/或壳体下部（10）的内部， 其中所述弹簧板（30）可操作地连接到单个向外设置的致动旋钮（40）。

公开(公告)号：US08323651B2

公开(公告)日：2012-12-04

申请号：US12437715

申请日：2009-05-08

Applicant: Jijie Gu ,  Chung-Ming Hsieh ,  Zhen Wu ,  Enrico L. DiGiammarino ,  Feng Luo ,  Gerard B. Fox ,  John E. Harlan ,  Martin Schmidt ,  Ralf Loebbert ,  Reinhold Mueller ,  Ulrich Ebert ,  Volker Nimmrich

Inventor： Jijie Gu ,  Chung-Ming Hsieh ,  Zhen Wu ,  Enrico L. DiGiammarino ,  Feng Luo ,  Gerard B. Fox ,  John E. Harlan ,  Martin Schmidt ,  Ralf Loebbert ,  Reinhold Mueller ,  Ulrich Ebert ,  Volker Nimmrich

IPC: A61K39/395 ,  C07H21/04 ,  C07K16/00 ,  A61P25/28 ,  C12N15/63 ,  C12N5/10 ,  C12P21/02

CPC classification number: C07K16/2803 ,  A61K2039/505 ,  C07K16/28 ,  C07K16/464 ,  C07K2317/14 ,  C07K2317/24 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92 ,  C12P21/005 ,  Y02A50/466

Abstract: The present application relates to isolated proteins, particularly monoclonal antibodies, in particular CDR-grafted, humanized antibodies which bind to RAGE protein. Specifically, these antibodies have the ability to inhibit the binding of RAGE to its various ligands. The antibodies or portions thereof of described in the present application are useful for treating a disease or disorder characterized by or induced by pathophysiological ligands of RAGE, for example misfolded proteins like amyloid β and advanced glycation-end-products.

Abstract translation: 本申请涉及分离的蛋白质，特别是单克隆抗体，特别是结合RAGE蛋白质的CDR-移植的人源化抗体。 具体地说，这些抗体具有抑制RAGE与其各种配体结合的能力。 本申请中描述的抗体或其部分可用于治疗由RAGE的病理生理学配体表征或诱导的疾病或病症，例如错误折叠的蛋白质如淀粉样蛋白和bgr; 和晚期糖基化终产物。

公开(公告)号：US08257105B2

公开(公告)日：2012-09-04

申请号：US12858326

申请日：2010-08-17

Applicant: Martin Schmidt ,  Frank Quast ,  Thomas Gieschke

Inventor： Martin Schmidt ,  Frank Quast ,  Thomas Gieschke

IPC: H01R13/627

CPC classification number: H01R13/508 ,  E05C19/06

Abstract: In order to lock a housing that consists of at least two parts, particularly a plug connector housing, a locking system that functions similar to a toggle lever mechanism is provided. In this case, a locking plate is arranged within a shell-shaped sliding element to both sides of a first and a second housing half and movably held on bearing pins on the second housing half, wherein latches are provided on the first housing half and engage into window openings provided in the locking plate for this purpose when the sliding element is displaced into its locking position in order to hold together the two housing halves.

Abstract translation: 为了锁定由至少两个部分组成的壳体，特别是插头连接器壳体，提供了类似于肘节杆机构的锁定系统。 在这种情况下，锁定板被布置在壳形滑动元件内，在第一和第二壳体半部的两侧，并且可移动地保持在第二壳体半部的轴承销上，其中闩锁设置在第一壳体半部上并且接合 当滑动元件移动到其锁定位置中以便将两个壳体半部保持在一起时，设置在锁定板中的窗口中用于此目的。