公开(公告)号：US09173999B2

公开(公告)日：2015-11-03

申请号：US13357936

申请日：2012-01-25

Applicant: Eric S. Edwards ,  Evan T. Edwards ,  Mark J. Licata ,  Paul F. Meyers ,  Frank E. Blondino

Inventor： Eric S. Edwards ,  Evan T. Edwards ,  Mark J. Licata ,  Paul F. Meyers ,  Frank E. Blondino

IPC: A61M5/31 ,  A61M5/315 ,  A61M5/20 ,  A61M5/32

CPC classification number: A61M5/2033 ,  A61M5/20 ,  A61M5/2066 ,  A61M5/315 ,  A61M5/3202 ,  A61M5/3204 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/208 ,  A61M2005/2086

Abstract: An apparatus includes a housing, a medicament container, and a movable assembly. The movable assembly includes a first movable member and a second movable member. The second movable member is configured to move relative to the first movable member to move the movable assembly from a first configuration to a second configuration. A distal end portion of the second movable member is configured to move a plunger disposed within the medicament container in a distal direction when the movable assembly is moved to the second configuration. The movable assembly is configured to move between a first position and a second position to move the medicament container within the housing between a first container position and a second container position.

Abstract translation: 一种装置包括壳体，药物容器和可移动组件。 可移动组件包括第一可动构件和第二可移动构件。 第二可移动部件构造成相对于第一可移动部件移动，以将可移动组件从第一构造移动到第二构造。 第二可移动部件的远端部分构造成当可移动组件移动到第二构造时沿远侧方向移动设置在药物容器内的柱塞。 可移动组件构造成在第一位置和第二位置之间移动，以在第一容器位置和第二容器位置之间移动壳体内的药物容器。

公开(公告)号：US08627816B2

公开(公告)日：2014-01-14

申请号：US13036720

申请日：2011-02-28

Applicant: Eric S. Edwards ,  Evan T. Edwards ,  Mark J. Licata ,  Frank E. Blondino

Inventor： Eric S. Edwards ,  Evan T. Edwards ,  Mark J. Licata ,  Frank E. Blondino

IPC: A61M11/00 ,  A61M37/00

CPC classification number: A61M5/002 ,  A61K31/485 ,  A61M5/2033 ,  A61M5/2046 ,  A61M5/2459 ,  A61M5/3232 ,  A61M5/5086 ,  A61M11/00 ,  A61M11/007 ,  A61M15/0001 ,  A61M15/08 ,  A61M2202/048 ,  A61M2205/14 ,  A61M2205/3584 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/80 ,  A61M2205/8206 ,  A61M2209/06 ,  A61M2210/0618 ,  G09B5/04 ,  G09B19/24

Abstract: Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.

Abstract translation: 本文描述了用于施用阿片样物质拮抗剂的药物递送装置。 在一些实施例中，一种装置包括壳体，设置在壳体内的药物容器和设置在壳体内的能量存储构件。 填充药物容器，其纳纳酮组合物包括纳洛酮或其盐，张力调节剂和pH调节剂，由此纳洛酮组合物的重量摩尔渗透压浓度范围为约250-350mOsm，pH范围为约3- 5。 能量存储构件构造成产生输送纳络酮组合物的力。

公开(公告)号：US08313466B2

公开(公告)日：2012-11-20

申请号：US13226867

申请日：2011-09-07

Applicant: Evan T Edwards ,  Eric S Edwards ,  Mark J Licata

Inventor： Evan T Edwards ,  Eric S Edwards ,  Mark J Licata

IPC: A61M37/00

CPC classification number: A61M5/19 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/24 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2205/14 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6036 ,  G06F19/00 ,  G06F19/3468

Abstract: An apparatus includes a housing, a medicament container and an actuator. The actuator includes a release member and an energy storage member having a first position and a second position. In the first position, the energy storage member has a first potential energy. In the second position the energy storage member has a second potential energy. The energy storage member is configured to convert a portion of the first potential energy into kinetic energy when moved from the first position to the second position to move the medicament container within the housing. The energy storage member has a longitudinal axis offset from a longitudinal axis of the medicament container. The release member is configured to selectively deploy the energy storage member from its first position to its second position.

Abstract translation: 一种装置包括壳体，药物容器和致动器。 致动器包括释放构件和具有第一位置和第二位置的能量存储构件。 在第一位置，能量存储构件具有第一势能。 在第二位置，能量存储构件具有第二势能。 能量存储构件被构造成当从第一位置移动到第二位置时将第一势能的一部分转换成动能，以使药物容器在壳体内移动。 能量存储构件具有从药物容器的纵向轴线偏离的纵向轴线。 释放构件被构造成将能量存储构件从其第一位置选择性地展开到其第二位置。

公开(公告)号：US08172082B2

公开(公告)日：2012-05-08

申请号：US11671025

申请日：2007-02-05

Applicant: Eric Shawn Edwards ,  Evan Thomas Edwards ,  Mark J. Licata ,  T. Spencer Williamson

Inventor： Eric Shawn Edwards ,  Evan Thomas Edwards ,  Mark J. Licata ,  T. Spencer Williamson

IPC: B65D85/72

CPC classification number: A61M5/19 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/326 ,  A61M5/3287 ,  A61M2005/2026 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2039/1083 ,  A61M2039/1088 ,  A61M2205/13 ,  A61M2205/14 ,  A61M2205/18 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6036 ,  G06F19/00 ,  G06F19/3468 ,  G16H20/17

Abstract: An apparatus includes a container defining an internal region configured to contain multiple medicament delivery devices, such as, for example, pen injectors, auto-injectors, inhalers or the like. The container includes an electronic circuit system configured to output a first electronic output associated with a first medicament delivery device contained within the internal region when the first medicament delivery device is removed from the internal region of the container. The electronic circuit system is further configured to output a second electronic output associated with a second medicament delivery device contained within the internal region when the second medicament delivery device is removed from the internal region of the container. The second electronic output is different than the first electronic output. At least one of the first electronic output or the second electronic output is associated with a use instruction.

Abstract translation: 一种装置包括限定内部区域的容器，该内部区域被配置为容纳多个药物输送装置，例如笔式注射器，自动注射器，吸入器等。 容器包括电子电路系统，该电子电路系统被配置为当第一药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第一药物输送装置相关联的第一电子输出。 电子电路系统还被配置为当第二药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第二药物输送装置相关联的第二电子输出。 第二个电子输出与第一个电子输出不同。 第一电子输出或第二电子输出中的至少一个与使用指令相关联。

公开(公告)号：US07648482B2

公开(公告)日：2010-01-19

申请号：US11562061

申请日：2006-11-21

Applicant: Evan Thomas Edwards ,  Eric Shawn Edwards ,  Mark J. Licata

Inventor： Evan Thomas Edwards ,  Eric Shawn Edwards ,  Mark J. Licata

IPC: A61M5/20

CPC classification number: A61M5/19 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/24 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2205/14 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6036 ,  G06F19/00 ,  G06F19/3468

Abstract: An apparatus includes a housing, a medicament container and an actuator. The actuator includes a release member and an energy storage member having a first position and a second position. In the first position, the energy storage member has a first potential energy. In the second position the energy storage member has a second potential energy. The energy storage member is configured to convert a portion of the first potential energy into kinetic energy when moved from the first position to the second position to move the medicament container within the housing. The energy storage member has a longitudinal axis offset from a longitudinal axis of the medicament container. The release member is configured to selectively deploy the energy storage member from its first position to its second position.

Abstract translation: 一种装置包括壳体，药物容器和致动器。 致动器包括释放构件和具有第一位置和第二位置的能量存储构件。 在第一位置，能量存储构件具有第一势能。 在第二位置，能量存储构件具有第二势能。 能量存储构件被构造成当从第一位置移动到第二位置时将第一势能的一部分转换成动能，以使药物容器在壳体内移动。 能量存储构件具有从药物容器的纵向轴线偏离的纵向轴线。 释放构件被构造成将能量存储构件从其第一位置选择性地展开到其第二位置。

公开(公告)号：US09327077B2

公开(公告)日：2016-05-03

申请号：US13550999

申请日：2012-07-17

Applicant: Eric S. Edwards ,  Evan T. Edwards ,  Mark J. Licata ,  Paul F. Meyers ,  David A. Weinzierl ,  T. Spencer Williamson, IV

Inventor： Eric S. Edwards ,  Evan T. Edwards ,  Mark J. Licata ,  Paul F. Meyers ,  David A. Weinzierl ,  T. Spencer Williamson, IV

IPC: A61M37/00 ,  A61M5/19 ,  A61M5/20 ,  A61M5/32 ,  A61M15/00 ,  G06F19/00 ,  A61M5/315 ,  A61M5/24 ,  A61M5/31

CPC classification number: A61M5/20 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/24 ,  A61M5/2448 ,  A61M5/3129 ,  A61M5/315 ,  A61M5/3204 ,  A61M5/326 ,  A61M15/0001 ,  A61M15/008 ,  A61M15/009 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/314 ,  A61M2205/14 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/3569 ,  A61M2205/3576 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/43 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6036 ,  A61M2205/8206 ,  G06F19/00 ,  G06F19/3468

Abstract: A system includes a medicament delivery device and a container configured to receive at least a portion of the medicament delivery device. The medicament delivery device includes an actuator and a first electronic circuit system. The actuator is configured to initiate delivery of a medicament into a body when the actuator is moved from a first position to a second position. The first electronic circuit system is configured to output a first electronic signal when the actuator is moved from the first position to the second position. The container includes a second electronic circuit system configured to receive the first electronic signal. The second electronic circuit system is configured to output a second electronic signal associated with the first electronic signal.

公开(公告)号：US08920367B2

公开(公告)日：2014-12-30

申请号：US13326959

申请日：2011-12-15

Applicant: Eric Shawn Edwards ,  Evan Thomas Edwards ,  Mark J. Licata ,  Paul F. Meyers

Inventor： Eric Shawn Edwards ,  Evan Thomas Edwards ,  Mark J. Licata ,  Paul F. Meyers

IPC: A61M37/00 ,  A61M5/20 ,  A61M5/19 ,  G06F19/00 ,  A61M5/32 ,  A61M39/10 ,  A61M5/24

CPC classification number: A61M5/19 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/326 ,  A61M5/3287 ,  A61M2005/2026 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2039/1083 ,  A61M2039/1088 ,  A61M2205/13 ,  A61M2205/14 ,  A61M2205/18 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6036 ,  G06F19/00 ,  G06F19/3468 ,  G16H20/17

Abstract: An apparatus includes a medicament container assembly, a movable assembly, and a spring. The medicament container assembly includes a first plunger defining a first volume, and a second plunger defining a second volume. The movable assembly includes a first movable member and a second movable member. The second movable member can move the second plunger within the medicament container assembly. The first movable member can move the first plunger in a first direction within the medicament container assembly to expel a contents of at least the first volume via a needle. The spring is configured to urge the needle in a second direction. The release portion of the first movable member is configured to contact the second movable member after the first movable member moves the first plunger to enable the spring to move the needle in the second direction.

Abstract translation: 一种装置包括药物容器组件，可移动组件和弹簧。 药物容器组件包括限定第一容积的第一柱塞和限定第二体积的第二柱塞。 可移动组件包括第一可动构件和第二可移动构件。 第二可移动部件可以将药剂容器组件内的第二柱塞移动。 第一可移动部件可以在药物容器组件内沿第一方向移动第一柱塞，以经由针排出至少第一体积的内容物。 弹簧构造成在第二方向上推动针。 第一可动构件的释放部分构造成在第一可动构件移动第一柱塞之后接触第二可动构件，以使弹簧能够沿第二方向移动针。

公开(公告)号：US08544645B2

公开(公告)日：2013-10-01

申请号：US13464234

申请日：2012-05-04

Applicant: Eric Shawn Edwards ,  Evan Thomas Edwards ,  Mark J. Licata ,  T. Spencer Williamson

Inventor： Eric Shawn Edwards ,  Evan Thomas Edwards ,  Mark J. Licata ,  T. Spencer Williamson

IPC: B65D83/10

CPC classification number: A61M5/19 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/326 ,  A61M5/3287 ,  A61M2005/2026 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2039/1083 ,  A61M2039/1088 ,  A61M2205/13 ,  A61M2205/14 ,  A61M2205/18 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6036 ,  G06F19/00 ,  G06F19/3468 ,  G16H20/17

Abstract: An apparatus includes a container defining an internal region configured to contain multiple medicament delivery devices, such as, for example, pen injectors, auto-injectors, inhalers or the like. The container includes an electronic circuit system configured to output a first electronic output associated with a first medicament delivery device contained within the internal region when the first medicament delivery device is removed from the internal region of the container. The electronic circuit system is further configured to output a second electronic output associated with a second medicament delivery device contained within the internal region when the second medicament delivery device is removed from the internal region of the container. The second electronic output is different than the first electronic output. At least one of the first electronic output or the second electronic output is associated with a use instruction.

Abstract translation: 一种装置包括限定内部区域的容器，该内部区域被配置为容纳多个药物输送装置，例如笔式注射器，自动注射器，吸入器等。 容器包括电子电路系统，该电子电路系统被配置为当第一药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第一药物输送装置相关联的第一电子输出。 电子电路系统还被配置为当第二药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第二药物输送装置相关联的第二电子输出。 第二个电子输出与第一个电子输出不同。 第一电子输出或第二电子输出中的至少一个与使用指令相关联。

公开(公告)号：US20130190692A1

公开(公告)日：2013-07-25

申请号：US13550893

申请日：2012-07-17

Applicant: Eric S. EDWARDS ,  Evan T. EDWARDS ,  Mark J. LICATA ,  Paul F. MEYERS ,  David A. WEINZIERL

Inventor： Eric S. EDWARDS ,  Evan T. EDWARDS ,  Mark J. LICATA ,  Paul F. MEYERS ,  David A. WEINZIERL

IPC: A61M5/31

CPC classification number: A61M5/5086 ,  A61M5/2053 ,  A61M5/24 ,  A61M5/31 ,  A61M5/3202 ,  A61M5/3287 ,  A61M15/0001 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/3125 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/584 ,  A61M2205/587 ,  A61M2205/6027 ,  A61M2205/6063 ,  A61M2205/8206 ,  G06F19/00 ,  G06F19/3468 ,  G09B23/28 ,  G09B23/285

Abstract: Medicament delivery devices are described herein. In some embodiments, an apparatus includes a medical injector and an electronic circuit system. The medical injector includes a housing, a medicament container, and a medicament delivery member. The housing defines a first region and a second region. The first region includes the medicament container and is physically isolated from the second region. The electronic circuit system is configured to be disposed within the second region defined by the housing. The electronic circuit system is configured to output an electronic output associated with a use of the medical injector.

Abstract translation: 本文描述了药物输送装置。 在一些实施例中，装置包括医用注射器和电子电路系统。 医用注射器包括壳体，药物容器和药物输送构件。 壳体限定第一区域和第二区域。 第一区域包括药物容器并与第二区域物理隔离。 电子电路系统被配置为设置在由壳体限定的第二区域内。 电子电路系统被配置为输出与医用注射器的使用相关联的电子输出。

公开(公告)号：US20120280815A1

公开(公告)日：2012-11-08

申请号：US13464234

申请日：2012-05-04

Applicant: Eric Shawn EDWARDS ,  Evan Thomas EDWARDS ,  Mark J. LICATA ,  T. Spencer WILLIAMSON

Inventor： Eric Shawn EDWARDS ,  Evan Thomas EDWARDS ,  Mark J. LICATA ,  T. Spencer WILLIAMSON

IPC: G08B13/14

CPC classification number: A61M5/19 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/326 ,  A61M5/3287 ,  A61M2005/2026 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2039/1083 ,  A61M2039/1088 ,  A61M2205/13 ,  A61M2205/14 ,  A61M2205/18 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2205/6036 ,  G06F19/00 ,  G06F19/3468 ,  G16H20/17

Abstract: An apparatus includes a container defining an internal region configured to contain multiple medicament delivery devices, such as, for example, pen injectors, auto-injectors, inhalers or the like. The container includes an electronic circuit system configured to output a first electronic output associated with a first medicament delivery device contained within the internal region when the first medicament delivery device is removed from the internal region of the container. The electronic circuit system is further configured to output a second electronic output associated with a second medicament delivery device contained within the internal region when the second medicament delivery device is removed from the internal region of the container. The second electronic output is different than the first electronic output. At least one of the first electronic output or the second electronic output is associated with a use instruction.

Abstract translation: 一种装置包括限定内部区域的容器，该内部区域被配置为容纳多个药物输送装置，例如笔式注射器，自动注射器，吸入器等。 容器包括电子电路系统，该电子电路系统被配置为当第一药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第一药物输送装置相关联的第一电子输出。 电子电路系统还被配置为当第二药物输送装置从容器的内部区域移除时，输出与包含在内部区域内的第二药物输送装置相关联的第二电子输出。 第二个电子输出与第一个电子输出不同。 第一电子输出或第二电子输出中的至少一个与使用指令相关联。