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    SYSTEM FOR REDUCING MATERNAL MORTALITY AND METHOD OF USE THEREOF
    2.
    发明公开
    SYSTEM FOR REDUCING MATERNAL MORTALITY AND METHOD OF USE THEREOF 审中-公开

    公开(公告)号：US20240105295A1

    公开(公告)日：2024-03-28

    申请号：US17935386

    申请日：2022-09-26

    Applicant: Morehouse School of Medicine

    Inventor： Natalie HERNANDEZ ,  Andrea G. Parker ,  Rasheeta Chandler

    IPC: G16H10/65

    CPC classification number: G16H10/65 ,  G16H10/20

    Abstract: A method for monitoring and/or modifying behavior to reducing maternal mortality risk, including the steps of receiving, via a user interface of an application executing on one or more computer processors, a self-surveillance module, wherein said self-surveillance module comprises inputs from the subject for personal information for a plurality of types of information selected from the types of information comprising doctor appointments, physiologic parameters, mental health survey results, indicators of social instability and personally recorded expression; determining, via the one or more computer processors, a total abnormality point value of trends for in the subject via the one or more computer processors, based on the sum total of abnormality point values in real-time, wherein when the total abnormality point value of the trends for the subject exceeds a pre-selected point value an abnormality alert is generated.

    METHOD AND SYSTEM OF DIAGNOSING AND TREATING NEURODEGENERATIVE DISEASE AND SEIZURES
    5.
    发明申请
    METHOD AND SYSTEM OF DIAGNOSING AND TREATING NEURODEGENERATIVE DISEASE AND SEIZURES 有权

    公开(公告)号：US20230010690A1

    公开(公告)日：2023-01-12

    申请号：US17305480

    申请日：2021-07-08

    Applicant: Morehouse School of Medicine

    Inventor： Robert Meller ,  Roger P. Simon

    IPC: C12Q1/6883 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6869 ,  A61K45/06

    Abstract: A method of distinguishing a subject with pre-clinical Alzheimer's disease from those with similar symptoms but other forms of dementia such as mild cognitive impairment. The blood RNA whole transcriptome profile of a subject with suspected pre-clinical Alzheimer's disease is obtained and analyzed against a reference blood RNA whole transcriptome profile from a subject with another form of dementia such as frontal temporal dementia, CADASIL or mild cognitive impairment (MCI). The blood RNA whole transcriptome profile includes the presence and quantitation of ncRNA. Methods to enhance treatment of epileptic seizures are also discussed.

    COMPOSITIONS AND METHODS FOR TREATING SARS-CoV-2 INFECTIONS
    6.
    发明申请
    COMPOSITIONS AND METHODS FOR TREATING SARS-CoV-2 INFECTIONS 有权

    公开(公告)号：US20220389063A1

    公开(公告)日：2022-12-08

    申请号：US17806210

    申请日：2022-06-09

    Applicant: MOREHOUSE SCHOOL OF MEDICINE

    Inventor： VINCENT C. BOND ,  Ming Bo Huang ,  James W. Lillard, JR.

    IPC: C07K14/16 ,  A61P31/14 ,  A61K47/54 ,  A61K47/60 ,  A61K45/06

    Abstract: The present application relates to methods and compositions and methods for treating viral infections, especially those caused by SARS-CoV-2. In one aspect, a method of treatment comprises administering to a subject in need of such treatment an effective amount of a pharmaceutical composition comprising a multipartite SARS-CoV-2-inhibiting peptide comprising a secretion modulating region (VI-SMR) peptide from HIV-1 Nef in combination with a cell-penetrating peptide (CPP) domain, a Clusterin (Clu)-binding peptide (Clu-BP) domain, a mitochondrial targeting (Mito-T) peptide domain, an anti-fusogenic (AF) peptide domain, a viral attachment inhibitor (VAI) domain or combination thereof, optionally where the SARS-CoV-2-inhibiting peptide is pegylated and/or modified with one or more hydrophobic domains.

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