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公开(公告)号：US20180273898A1
公开(公告)日：2018-09-27
申请号：US15587386
申请日：2017-05-04
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Zhen-Yu Guan
IPC: C12N5/00 , A61L27/54 , A61L27/34 , C12N5/0775
CPC classification number: C12N5/0018 , A61L27/34 , A61L27/54 , A61L2300/412 , A61L2300/414 , A61L2300/42 , A61L2400/18 , C12N2533/30 , C12N2533/52 , C08L65/04
Abstract: The present invention provides a biological material including a parylene C film; and first proteins which are adsorbed on the surface of the parylene C film. According to an embodiment of the present invention, the biological material further includes second proteins different from the first proteins adsorbed on the surface of the parylene C film. According to an embodiment of the present invention, the first proteins or the second proteins include BMP-2, fibronectin or PRP.
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公开(公告)号：US09862799B2
公开(公告)日：2018-01-09
申请号：US14529175
申请日：2014-10-31
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Hsin-Ying Ho , Ho-Yi Sun , Cheng-Yuan Fang
CPC classification number: C08G61/025 , B01J2/04 , B29K2045/00 , C08G2261/11 , C08G2261/1426 , C08G2261/1428 , C08G2261/143 , C08G2261/3424 , C08G2261/70 , C08J3/07 , C08L65/04
Abstract: Provided is a poly-p-xylyene having at least one chemically active functional group present in a form of particles. In an embodiment, the functionalized poly-p-xylylene is synthesized via CVD, and electrospinning is then performed at a relatively low polymer concentration, so as to produce functionalized poly-p-xylylene particles. The functionalized poly-p-xylyene particles have a particle size at nano-scale or micro-scale. Such functionalized poly-p-xylyene particles can be applied to biological fields extensively.
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公开(公告)号：US10246412B2
公开(公告)日：2019-04-02
申请号：US15185003
申请日：2016-06-16
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Zhen-Yu Guan , Chih-Yu Wu
IPC: C07C319/22 , C07C17/16 , C07C29/14 , C07C45/30 , C07C209/08 , C09D165/04 , C07C45/45 , C07C22/04
Abstract: The present invention provides a method of forming paracyclyophane containing disulfide functional group. The paracyclophane is prepared by adding 3,3′-dithiodipropionic acid (DPDPA) and N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide (EDC) into 4-aminomethyl [2,2] paracyclophane. The present invention further provides a chemical film and a method of forming the same. The chemical film contains poly-p-xylylene with disulfide functional group and is formed on a substrate by a chemical vapor deposition process.
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公开(公告)号：US20180201749A1
公开(公告)日：2018-07-19
申请号：US15475163
申请日：2017-03-31
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Hsing-Ying Tung
CPC classification number: C08J9/26 , C08G61/025 , C08G2261/3424 , C08J2201/042 , C08J2365/04 , C23C16/01 , C23C16/30 , C23C16/44
Abstract: The present invention provides a 3D porous structure of parylene including a poly-p-xylylenes structure having a plurality of pores. The poly-p-xylylenes structure has a porosity. According to an embodiment of the present invention, the size of the porous structure is between 20 nm and 5 cm. According to an embodiment of the present invention, the porosity is between 55% and 85%. According to an embodiment of the present invention, the porous structure further includes a plurality of target molecules. According to an embodiment of the present invention, the pores of the poly-p-xylylenes structure include pore sizes of different sizes. The pore sizes are varying in a gradient. According to an embodiment of the present invention, the porous structure is formed integrally.
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公开(公告)号：US11161957B2
公开(公告)日：2021-11-02
申请号：US15475163
申请日：2017-03-31
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Hsing-Ying Tung
Abstract: The present invention provides a 3D porous structure of parylene including a poly-p-xylylenes structure having a plurality of pores. The poly-p-xylylenes structure has a porosity. According to an embodiment of the present invention, the size of the porous structure is between 20 nm and 5 cm. According to an embodiment of the present invention, the porosity is between 55% and 85%. According to an embodiment of the present invention, the porous structure further includes a plurality of target molecules. According to an embodiment of the present invention, the pores of the poly-p-xylylenes structure include pore sizes of different sizes. The pore sizes are varying in a gradient. According to an embodiment of the present invention, the porous structure is formed integrally.
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Patent Agency Ranking
公开(公告)号：US10336692B2
公开(公告)日：2019-07-02
申请号：US15913940
申请日：2018-03-07
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Zhen-Yu Guan , Chih-Yu Wu
IPC: C07C319/22 , C07C17/16 , C07C29/14 , C07C45/30 , C07C209/08 , C09D165/04 , C07C45/45 , C07C22/04
Abstract: The present invention provides a method of forming paracyclyophane containing disulfide functional group. The paracyclophane is prepared by adding 3,3′-dithiodipropionic acid (DPDPA) and N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide (EDC) into 4-aminomethyl [2,2] paracyclophane. The present invention further provides a chemical film and a method of forming the same. The chemical film contains poly-p-xylylene with disulfide functional group and is formed on a substrate by a chemical vapor deposition process.
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公开(公告)号：US20170166520A1
公开(公告)日：2017-06-15
申请号：US15185003
申请日：2016-06-16
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Zhen-Yu Guan , Chih-Yu Wu
IPC: C07C319/22 , C09D165/04 , C07C29/14 , C07C45/30 , C07C209/08 , C07C17/16
CPC classification number: C07C319/22 , C07C17/16 , C07C22/04 , C07C29/14 , C07C45/30 , C07C45/45 , C07C209/08 , C07C2603/92 , C08G2261/1426 , C08G2261/1432 , C08G2261/145 , C08G2261/3424 , C09D165/04 , C07C323/60 , C07C211/31 , C07C33/34 , C07C47/546
Abstract: The present invention provides a method of forming paracyclyophane containing disulfide functional group. The paracyclophane is prepared by adding 3,3′-dithiodipropionic acid (DPDPA) and N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide (EDC) into 4-aminomethyl [2,2] paracyclophane. The present invention further provides a chemical film and a method of forming the same. The chemical film contains poly-p-xylylene with disulfide functional group and is formed on a substrate by a chemical vapor deposition process.
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公开(公告)号：US20150307653A1
公开(公告)日：2015-10-29
申请号：US14529175
申请日：2014-10-31
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Hsin-Ying Ho , Ho-Yi Sun , Cheng-Yuan Fang
CPC classification number: C08G61/025 , B01J2/04 , B29K2045/00 , C08G2261/11 , C08G2261/1426 , C08G2261/1428 , C08G2261/143 , C08G2261/3424 , C08G2261/70 , C08J3/07 , C08L65/04
Abstract: Provided is a poly-p-xylyene having at least one chemically active functional group present in a form of particles. In an embodiment, the functionalized poly-p-xylylene is synthesized via CVD, and electrospinning is then performed at a relatively low polymer concentration, so as to produce functionalized poly-p-xylylene particles. The functionalized poly-p-xylyene particles have a particle size at nano-scale or micro-scale. Such functionalized poly-p-xylyene particles can be applied to biological fields extensively.
Abstract translation: 提供具有以颗粒形式存在的至少一种化学活性官能团的聚对二甲苯苯胺。 在一个实施方案中，通过CVD合成官能化的聚对二甲苯，然后以相对较低的聚合物浓度进行静电纺丝，以产生官能化的聚对二甲苯颗粒。 官能化的聚对二甲苯亚胺颗粒具有纳米级或微尺度的粒径。 这种官能化的聚对二甲苯亚胺颗粒可广泛应用于生物领域。
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公开(公告)号：US20180265460A1
公开(公告)日：2018-09-20
申请号：US15913940
申请日：2018-03-07
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Zhen-Yu Guan , Chih-Yu Wu
IPC: C07C319/22 , C07C45/30 , C07C17/16 , C07C29/14 , C07C209/08 , C07C45/45 , C09D165/04 , C07C323/60 , C07C211/31 , C07C22/04 , C07C33/34 , C07C47/546
CPC classification number: C07C319/22 , C07C17/16 , C07C22/04 , C07C29/14 , C07C45/30 , C07C45/45 , C07C209/08 , C07C2603/92 , C08G2261/1426 , C08G2261/1432 , C08G2261/145 , C08G2261/3424 , C09D165/04 , C07C323/60 , C07C211/31 , C07C33/34 , C07C47/546
Abstract: The present invention provides a method of forming paracyclyophane containing disulfide functional group. The paracyclophane is prepared by adding 3,3′-dithiodipropionic acid (DPDPA) and N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide (EDC) into 4-aminomethyl [2,2] paracyclophane. The present invention further provides a chemical film and a method of forming the same. The chemical film contains poly-p-xylylene with disulfide functional group and is formed on a substrate by a chemical vapor deposition process.
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公开(公告)号：US20180243081A1
公开(公告)日：2018-08-30
申请号：US15963048
申请日：2018-04-25
Applicant: MAY-HWA ENTERPRISE CORPORATION
Inventor： Hsien-Yeh Chen , Shih-Kang Fan , Jyun-Ting Wu
CPC classification number: A61F2/1613 , A61F2/16 , A61F2002/1683 , B29D11/023 , C08G2261/3424 , C08L65/04
Abstract: The present invention provides a method of forming an intraocular lens. First, a chemical vapor deposition (CVD) process is performed to form a first poly-p-xylylene film, following by placing a solution drop on the first poly-p-xylylene film. A chemical vapor deposition encapsulation process is performed to form a second poly-p-xylylene film on the first poly-p-xylylene film and the solution drop.
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