公开(公告)号：US20100261262A1

公开(公告)日：2010-10-14

申请号：US12681049

申请日：2008-10-10

申请人： Kiyotaka Iwasaki ,  Mitsuo Umezu ,  Koji Kojima ,  Charles Alfred Vacanti

发明人： Kiyotaka Iwasaki ,  Mitsuo Umezu ,  Koji Kojima ,  Charles Alfred Vacanti

IPC分类号： A01N1/02

CPC分类号： A61F2/062 ,  C12M29/12 ,  C12M29/18 ,  C12M35/04 ,  C12M41/26

摘要： A system (10) for forming and maintaining a biological tissue by which a biological tissue can be artificially formed by culturing cells, which comprises a pulse pump (12), a circulation pathway (13) having such a circuit structure as allowing a liquid cell culture medium discharged from the pulse pump (12) to return into the pulse pump (12), and a cell culture section (14A) and a gas exchange section (14B) provided along the circulation pathway (13). The cell culture section (14A) holds a cell holder (H) in such a manner to form a first channel wherein the liquid cell culture medium flowing in the circulation pathway (13) passes through the cell holder (H) and returns into the circulation pathway (13) and a second channel wherein the liquid cell culture medium flowing in the circulation pathway (13) passes outside the cell holder (H) and returns into the circulation pathway (13), thereby bringing about a difference in pressure between the liquid cell culture medium passing through the respective channels. The gas exchange section (14B) supplies a mixed gas containing oxygen and carbon oxide to the liquid cell culture medium circulating within the circulation pathway (13) and thus controls the pH value of the liquid cell culture medium at a definite level.

摘要翻译： 一种用于形成和维持生物组织的系统（10），通过该生物组织可以通过培养细胞人造地形成生物组织，所述系统包括脉冲泵（12），具有允许液体细胞的电路结构的循环通路（13） 从脉冲泵（12）排出的返回到脉冲泵（12）的培养基，沿着循环通路（13）设置的细胞培养部（14A）和气体交换部（14B）。 细胞培养部（14A）以形成第一通道的方式保持细胞保持器（H），其中在循环路径（13）中流动的液体细胞培养基通过细胞保持器（H）并返回循环 通路（13）和第二通道，其中在所述循环通路（13）中流动的液体细胞培养基通过所述细胞保持器（H）的外部并返回到所述循环通路（13）中，从而导致所述液体 通过相应通道的细胞培养基。 气体交换部（14B）将含有氧和碳氧化物的混合气体供给到在循环路径（13）内循环的液体细胞培养基，从而将液体细胞培养基的pH值控制在一定水平。

公开(公告)号：US08713410B2

公开(公告)日：2014-04-29

申请号：US13301335

申请日：2011-11-21

申请人： Kiyotaka Iwasaki

发明人： Kiyotaka Iwasaki

IPC分类号： G11C29/00

CPC分类号： G06F11/1048 ,  G11C2029/0411

摘要： According to one embodiment, a data storage apparatus includes a channel controller, an error correction controller, and an additional correction module. The channel controller is configured to control writing to and reading from the nonvolatile memories of respective channels. The error correction controller is configured to use inter-channel error correction codes during any read process, performing inter-channel correction process on those of the data items read under the control of the channel controller, which have been designated. The additional correction module is configured to designate, in accordance with errors detected by the channel controller, data items to additionally correct, and to notify the data items so designated to the error correction controller while the channel controller is reading the data necessary in the inter-channel correction process.

摘要翻译： 根据一个实施例，数据存储装置包括信道控制器，纠错控制器和附加校正模块。 通道控制器被配置为控制对各个通道的非易失性存储器的写入和读取。 错误校正控制器被配置为在任何读取处理期间使用信道间纠错码，对已经指定的信道控制器的控制下读取的数据项执行信道间校正处理。 附加校正模块被配置为根据由信道控制器检测到的错误来指定数据项以附加地校正，并且在信道控制器正在读取在相互之间必需的数据时将如此指定的数据项通知给纠错控制器 通道校正过程。

公开(公告)号：US20130254454A1

公开(公告)日：2013-09-26

申请号：US13600578

申请日：2012-08-31

申请人： Takashi IDE ,  Kiyotaka IWASAKI ,  Kouji WATANABE ,  Hiroyuki NANJOU ,  Makoto MORIYA

发明人： Takashi IDE ,  Kiyotaka IWASAKI ,  Kouji WATANABE ,  Hiroyuki NANJOU ,  Makoto MORIYA

IPC分类号： G06F12/06

CPC分类号： G06F3/0611 ,  G06F3/0659 ,  G06F3/0688 ,  G06F12/0246 ,  G06F12/0607 ,  G06F13/14 ,  G06F13/18 ,  G06F2212/7208

摘要： According to embodiments, a memory system includes a plurality of memory chips configuring banks, an instruction generator, and a memory controller. The instruction generator generates a plurality of instructions. The memory controller is configured to execute memory accesses to the banks based on the instructions. Each memory access comprises a first command sequence and a second command sequence. The first command sequence causes in-bank processing shortly subsequent to the first command. The second command sequence is executed subsequent to the in-bank processing. The memory controller executes successively a second command sequence to a first bank based on a first instruction and a first command sequence to the first bank based on a second instruction subsequent to the first instruction, and then starts a memory access to a second bank based on a third instruction while the first bank is executing the in-bank processing caused by the first command sequence.

公开(公告)号：US20120192032A1

公开(公告)日：2012-07-26

申请号：US13301335

申请日：2011-11-21

申请人： Kiyotaka IWASAKI

发明人： Kiyotaka IWASAKI

IPC分类号： G11C29/00 ,  G06F11/16

CPC分类号： G06F11/1048 ,  G11C2029/0411

摘要： According to one embodiment, a data storage apparatus includes a channel controller, an error correction controller, and an additional correction module. The channel controller is configured to control writing to and reading from the nonvolatile memories of respective channels. The error correction controller is configured to use inter-channel error correction codes during any read process, performing inter-channel correction process on those of the data items read under the control of the channel controller, which have been designated. The additional correction module is configured to designate, in accordance with errors detected by the channel controller, data items to additionally correct, and to notify the data items so designated to the error correction controller while the channel controller is reading the data necessary in the inter-channel correction process.

摘要翻译： 根据一个实施例，数据存储装置包括信道控制器，纠错控制器和附加校正模块。 通道控制器被配置为控制对各个通道的非易失性存储器的写入和读取。 错误校正控制器被配置为在任何读取处理期间使用信道间纠错码，对已经指定的信道控制器的控制下读取的数据项执行信道间校正处理。 附加校正模块被配置为根据由信道控制器检测到的错误来指定数据项以附加地校正，并且在信道控制器正在读取在相互之间必需的数据时将如此指定的数据项通知给纠错控制器 通道校正过程。

公开(公告)号：US20120011303A1

公开(公告)日：2012-01-12

申请号：US13086240

申请日：2011-04-13

申请人： Kiyotaka Iwasaki ,  Hirotaka Suzuki ,  Tohru Fukuda ,  Motohiro Matsuyama ,  Yoshimasa Aoyama

发明人： Kiyotaka Iwasaki ,  Hirotaka Suzuki ,  Tohru Fukuda ,  Motohiro Matsuyama ,  Yoshimasa Aoyama

IPC分类号： G06F12/00

CPC分类号： G06F3/0632 ,  G06F3/0611 ,  G06F3/0634 ,  G06F3/0679

摘要： According to one embodiment, a memory control device includes a controller, a command queue module, a plurality of stage processors, and a skip module. The controller controls a data access command to a nonvolatile memory from a host. The command queue module queues a transfer request command corresponding to the data access command. The stage processors each perform stage processing related to the transfer request command queued by the command queue module. The skip module skips the stage processing by the stage processors in response to a shutdown command from the controller.

摘要翻译： 根据一个实施例，存储器控制装置包括控制器，命令队列模块，多个级处理器和跳过模块。 控制器控制来自主机的非易失性存储器的数据访问命令。 命令队列模块对与数据访问命令对应的传输请求命令进行排队。 舞台处理器各自执行与由命令队列模块排队的传送请求命令相关的舞台处理。 响应于来自控制器的关机命令，跳过模块跳过级处理器的级处理。

公开(公告)号：US08043854B2

公开(公告)日：2011-10-25

申请号：US10556400

申请日：2004-05-12

申请人： Mitsuo Umezu ,  Kiyotaka Iwasaki ,  Shigeyuki Ozaki ,  Yuji Morimoto ,  Osamu Endo

发明人： Mitsuo Umezu ,  Kiyotaka Iwasaki ,  Shigeyuki Ozaki ,  Yuji Morimoto ,  Osamu Endo

IPC分类号： A01N1/00

CPC分类号： A61K35/34 ,  A61F2/2415 ,  Y10S623/901

摘要： In the transplant of a living organism tissue, such as a heart valve, taken from an animal, etc. into a human body, a cell removing solution for removing original cells from the living organism tissue is provided with flow approximately equal to the bloodstream of transplant recipient living body, and the living organism tissue is placed in the flow so as to effect immersion of the living organism tissue in the cell removing solution. In the immersion, it is preferred that the living organism tissue placed in the cell removing solution, while being rotated, be irradiated with microwave. As a result, original cells can be removed from the living organism tissue uniformly and reliably, so that the biocompatibility of living organism tissue after transplant can be enhanced.

摘要翻译： 在将从动物等取出的生物体组织如心脏瓣膜等移植到人体内时，从生物体组织中除去原始细胞的细胞去除溶液具有大约等于 移植受体活体，并将活体组织置于流中，以使活体组织浸入细胞去除溶液中。 在浸渍中，优选将放置在细胞去除溶液中的活体组织在旋转的同时用微波照射。 结果，原始细胞可以均匀可靠地从生物体组织中去除，从而可以提高移植后活体组织的生物相容性。

公开(公告)号：US08748166B2

公开(公告)日：2014-06-10

申请号：US12681049

申请日：2008-10-10

申请人： Kiyotaka Iwasaki ,  Mitsuo Umezu ,  Koji Kojima ,  Charles Alfred Vacanti

发明人： Kiyotaka Iwasaki ,  Mitsuo Umezu ,  Koji Kojima ,  Charles Alfred Vacanti

IPC分类号： C12M3/00 ,  A61F2/04

CPC分类号： A61F2/062 ,  C12M29/12 ,  C12M29/18 ,  C12M35/04 ,  C12M41/26

摘要： A system (10) for forming and maintaining a biological tissue by which a biological tissue can be artificially formed by culturing cells, which comprises a pulse pump (12), a circulation pathway (13) having such a circuit structure as allowing a liquid cell culture medium discharged from the pulse pump (12) to return into the pulse pump (12), and a cell culture section (14A) and a gas exchange section (14B) provided along the circulation pathway (13). The cell culture section (14A) holds a cell holder (H) in such a manner to form a first channel wherein the liquid cell culture medium flowing in the circulation pathway (13) passes through the cell holder (H) and returns into the circulation pathway (13) and a second channel wherein the liquid cell culture medium flowing in the circulation pathway (13) passes outside the cell holder (H) and returns into the circulation pathway thereby bringing about a difference in pressure between the liquid cell culture medium passing through the respective channels.

摘要翻译： 一种用于形成和维持生物组织的系统（10），通过该生物组织可以通过培养细胞人造地形成生物组织，所述系统包括脉冲泵（12），具有允许液体细胞的电路结构的循环通路（13） 从脉冲泵（12）排出的返回到脉冲泵（12）的培养基，沿着循环通路（13）设置的细胞培养部（14A）和气体交换部（14B）。 细胞培养部（14A）以形成第一通道的方式保持细胞保持器（H），其中在循环路径（13）中流动的液体细胞培养基通过细胞保持器（H）并返回循环 通路（13）和第二通道，其中在循环通路（13）中流动的液体细胞培养基通过细胞保持器（H）的外部并返回到循环通道中，从而导致液体细胞培养基通过之间的压力差 通过各自的渠道。

公开(公告)号：US08491308B2

公开(公告)日：2013-07-23

申请号：US12676735

申请日：2008-02-29

申请人： Kiyotaka Iwasaki ,  Mitsuo Umezu ,  Akira Nishikohri ,  Shunsuke Tsubouchi

发明人： Kiyotaka Iwasaki ,  Mitsuo Umezu ,  Akira Nishikohri ,  Shunsuke Tsubouchi

IPC分类号： G09B23/28

CPC分类号： G01N3/32 ,  A61F2/86 ,  A61F2240/008 ,  G01N2203/0017

摘要： It is intended to provide an endurance test apparatus whereby the behaviors of a vessel caused by a biomechanical burden can be simulated using a relatively simple constitution so that the endurance of a medical instrument (for example, a stent or an artificial vessel after anastomosis) can be tested in a similar state to an actual vessel, and an endurance test method therefor. Namely, an endurance test apparatus (10) comprises a simulated vessel (31) made of an elastic body, first and second holding members (32, 33) respectively supporting the both ends in the axial direction of the simulated vessel (31) and making the both ends relatively rotatable and interval-adjustable, and first and second motors (14, 15) operating these holding members (32, 33). The simulated vessel (31) is supported by the first and second holding members (32, 33) in a state stretched from its inherent length under a tensile force. Due to the driving motors (14, 15), the holding members (32, 33) elongate and contract the simulated vessel (31), which is in the stretched state as described above, while twisting it.

摘要翻译： 旨在提供一种耐久性测试装置，由此可以使用相对简单的结构来模拟由生物力学负担引起的血管的行为，使得医疗器械（例如支架或吻合后的人造血管）的耐久性可以 以与实际船舶类似的状态进行测试，以及其耐久性测试方法。 也就是说，耐久性试验装置（10）包括由弹性体制成的模拟容器（31），分别支撑模拟容器（31）的轴向两端的第一和第二保持构件（32,33），并使 两端相对旋转并可间隔地调节，第一和第二电动机（14,15）操作这些保持构件（32,33）。 模拟容器（31）由第一和第二保持构件（32,33）以其拉伸力从其固有长度拉伸的状态支撑。 由于驱动马达（14,15），保持构件（32,33）在被扭转的同时使处于处于拉伸状态的模拟容器（31）伸长并收缩。

公开(公告)号：US20120278538A1

公开(公告)日：2012-11-01

申请号：US13421618

申请日：2012-03-15

申请人： Takahiro Nango ,  Hiroyuki Moro ,  Motohiro Matsuyama ,  Kiyotaka Iwasaki

发明人： Takahiro Nango ,  Hiroyuki Moro ,  Motohiro Matsuyama ,  Kiyotaka Iwasaki

IPC分类号： G06F12/00

CPC分类号： G06F12/0246 ,  G06F2212/7202

摘要： According to one embodiment, a data storage apparatus includes a memory module and a controller. The memory module has a plurality of flash memory chips. Data is written to or read from each flash memory chip having a specific page size as access unit. The controller is configured to supply memory control signals, which are independent of the common signal containing the data and addresses, to the flash memory chips, respectively, in order to write data larger than the specific data size to the memory module. In the memory module, the respective flash memory chips store the data, each at the same address, in response to the memory control signals.

摘要翻译： 根据一个实施例，数据存储装置包括存储器模块和控制器。 存储器模块具有多个闪存芯片。 将数据写入或读取具有特定页面大小的每个闪存芯片作为存取单元。 控制器被配置为分别向闪速存储器芯片提供独立于包含数据和地址的公共信号的存储器控​​制信号，以将大于特定数据大小的数据写入存储器模块。 在存储器模块中，相应的闪存芯片响应于存储器控制信号将数据存储在相同的地址处。

公开(公告)号：US20120017116A1

公开(公告)日：2012-01-19

申请号：US13082048

申请日：2011-04-07

申请人： Motohiro Matsuyama ,  Hirotaka Suzuki ,  Kiyotaka Iwasaki ,  Tohru Fukuda

发明人： Motohiro Matsuyama ,  Hirotaka Suzuki ,  Kiyotaka Iwasaki ,  Tohru Fukuda

IPC分类号： G06F11/14 ,  G06F11/07

CPC分类号： G06F11/2017 ,  G06F11/073 ,  G06F11/0751 ,  G06F11/1068

摘要： According to one embodiment, a memory control device includes a first controller, a second controller, an access module, and a response sort module. The first controller controls processing of a data access command to a nonvolatile memory from a host. The second controller controls processing assigned to the second controller between the first controller and the second controller. The access module performs data access to the nonvolatile memory in response to a command from the first controller or the second controller. When an error occurs in the data access by the access module, the response sort module returns a response to the second controller instead of the first controller.

摘要翻译： 根据一个实施例，存储器控制装置包括第一控制器，第二控制器，访问模块和响应分类模块。 第一控制器控制从主机向非易失性存储器的数据访问命令的处理。 第二控制器控制分配给第一控制器和第二控制器之间的第二控制器的处理。 响应于来自第一控制器或第二控制器的命令，访问模块执行对非易失性存储器的数据访问。 当访问模块的数据访问发生错误时，响应排序模块返回对第二控制器而不是第一控制器的响应。