公开(公告)号：US20130218581A1

公开(公告)日：2013-08-22

申请号：US13456491

申请日：2012-04-26

Applicant: Natalie Anne Leech Catlett ,  David Alan Drubin ,  Keith Owen Elliston ,  Renee Marie Deehan Kenney ,  Michael Paul Macoritto

Inventor： Natalie Anne Leech Catlett ,  David Alan Drubin ,  Keith Owen Elliston ,  Renee Marie Deehan Kenney ,  Michael Paul Macoritto

IPC: G06Q50/22

CPC classification number: G06Q50/22 ,  G06Q30/0204 ,  G16B20/00 ,  G16B25/00 ,  G16H10/20

Abstract: A method of stratifying a set of disease-exhibiting patients prior to clinical trial of a target therapy begins by using a molecular footprint derived from a knowledgebase and other patient data to identify genes that are differentially expressed in a direction consistent with increase in the target activity. Therapeutic target “signaling strength” in individual patients of the set is then assessed using the genes identified and a strength algorithm. Based on their therapeutic target signaling strength, the set of disease-exhibiting patients are then stratified along a continuum. One or more gene expressions or other biomarkers may be specified for use in categorizing other disease-exhibiting patient populations. Alternative therapeutic targets are analyzed with respect to the likely non-responders, as evidenced by their differential signaling strength.

Abstract translation: 在靶治疗临床试验之前分层一组疾病展现患者的方法开始于使用来自知识库和其他患者数据的分子足迹来鉴定与靶活性增加一致的方向上差异表达的基因 。 然后使用所鉴定的基因和强度算法评估该组个体患者的治疗靶标“信号强度”。 根据其治疗目标信号强度，一组疾病展现患者沿着连续体分层。 可以指定一种或多种基因表达或其他生物标志物用于对其他疾病展示患者群体进行分类。 对于可能的无应答者，分析替代治疗目标，如其差异信号强度所证明的。

公开(公告)号：US20080007189A1

公开(公告)日：2008-01-10

申请号：US11857404

申请日：2007-09-18

Applicant: Mark Hunt ,  Keith Owen ,  Michael Hughes

Inventor： Mark Hunt ,  Keith Owen ,  Michael Hughes

IPC: G05B11/01 ,  H05B37/00

CPC classification number: H05B37/029 ,  F21V11/10 ,  F21W2131/406

Abstract: A stage lighting lamp unit includes a processor for receiving control data from a remote console. Beam orientation data for the lamp unit is passed to the lamp in the form of the x, y and z co-ordinates of a point in space through which the beam is to pass. The processor divides the required lamp travel into a number of stages dependent on execution duration data sent with the position data, and calculates, for each stage, a new value for pan and tilt angles for the lamp. These values are passed to pan and tilt controlling co-processors which control servo-motors for pan and tilt operation. The lamp unit also incorporates a rotatable shutter for interrupting the lamp beam when required. The shutters of all the lamps in a system can be instructed from the remote console to open and close in synchronism, thereby providing a stroboscopic effect.

Abstract translation: 舞台灯具单元包括用于从远程控制台接收控制数据的处理器。 灯单元的光束取向数据以光束通过的空间点的x，y和z坐标的形式传递到灯。 处理器根据与位置数据一起发送的执行持续时间数据将所需的灯行程划分为多个阶段，并为每个阶段计算灯的平移和倾斜角的新值。 这些值被传递给控制协调处理器，用于控制伺服电机进行摇摄和倾斜操作。 灯单元还包括可旋转的快门，用于在需要时中断灯光束。 系统中所有灯的快门可以从远程控制台指示同步打开和关闭，从而提供频闪效果。

公开(公告)号：US5718830A

公开(公告)日：1998-02-17

申请号：US601805

申请日：1996-02-15

Applicant: Charles George Hlinka ,  Janet Louise Markham ,  Casimir Roman Nijander ,  Keith Owen Mersereau ,  Yiu-Huen Wong

Inventor： Charles George Hlinka ,  Janet Louise Markham ,  Casimir Roman Nijander ,  Keith Owen Mersereau ,  Yiu-Huen Wong

IPC: B29C41/08 ,  B29C41/34 ,  B29C59/02 ,  B29D11/00 ,  G02B6/12 ,  G02B6/122 ,  B44C1/22 ,  G02B1/00

CPC classification number: B29C59/026 ,  B29C41/08 ,  B29C41/34 ,  B29D11/00365 ,  G02B6/1221 ,  B29C2791/001 ,  B29K2033/12 ,  G02B2006/12102

Abstract: A method for making a microlens comprising the steps of uniformly distributing a volume of Poly(methylmethacrylate) (PMMA) across a major surface of a substrate, hardening the PMMA layer on the substrate surface, patterning the PMMA layer and forming patterned PMMA and reflowing the patterned PMMA to form at least one microlens on the substrate.

Abstract translation: 一种制备微透镜的方法，包括以下步骤：在衬底的主表面上均匀分布一定量的聚（甲基丙烯酸甲酯）（PMMA）体系，使衬底表面上的PMMA层硬化，图案化PMMA层并形成图案化PMMA并回流 图案化的PMMA在基底上形成至少一个微透镜。

公开(公告)号：US5666155A

公开(公告)日：1997-09-09

申请号：US265366

申请日：1994-06-24

Applicant: Keith Owen Mersereau

Inventor： Keith Owen Mersereau

IPC: G02B3/00 ,  G02B27/02 ,  H04N7/14

CPC classification number: G02B3/0018 ,  G02B27/02 ,  H04N7/144 ,  G02B3/0056

Abstract: An apparatus for creating an illusion of eye contact in a video telephony system includes a video camera and a display screen. The video camera is aligned with the display screen so the viewer's image is transmitted by the video camera with the illusion of eye contact. The display screen has an array of lenses defining part of a first optical path, for transmitting to a video camera a viewer's image. An array of regions interspersed among the array of lenses defines part of a second optical path, for directing to the viewer, displayed images. The array of lenses and the array of regions are each too small to be separately resolvable by the human eye, so that the lenses do not interfere with the perceived quality of the transmitted viewer's image, and the transparent regions do not deteriorate noticeably the video display images projected to the viewer.

Abstract translation: 一种用于在视频电话系统中产生眼睛接触的错觉的装置包括摄像机和显示屏。 视频摄像机与显示屏对齐，使得观看者的图像由摄像机以眼睛接触的幻觉传输。 显示屏具有定义第一光路的一部分的透镜阵列，用于向摄像机发送观看者的图像。 散布在透镜阵列之间的区域阵列限定了第二光路的一部分，用于引导观看者显示的图像。 透镜阵列和阵列阵列的每一个都太小了，不能由人眼单独分辨，所以透镜不会干扰传送的观察者的图像的感知质量，透明区域不会显着地恶化视频显示 投影到观众的图像。

公开(公告)号：US4246079A

公开(公告)日：1981-01-20

申请号：US106096

申请日：1979-12-21

Applicant: Robert R. Goodrich ,  Robert G. Kunz ,  Sydney Lipton ,  Keith Owen

Inventor： Robert R. Goodrich ,  Robert G. Kunz ,  Sydney Lipton ,  Keith Owen

IPC: C07C7/148 ,  C10G19/02 ,  C25B1/16 ,  C25B1/20

CPC classification number: C07C7/1485 ,  C10G19/02 ,  C25B1/16

Abstract: A process for reducing the sulfur concentration in a fluid, such as a hydrocarbon gas stream is disclosed. The process comprises contacting the fluid with an aqueous alkali metal hydroxide solution and subsequently contacting the resulting liquid effluent with carbon dioxide to form an aqueous alkali metal carbonate salt solution and a volatile sulfur compound. The aqueous alkali metal carbonate salt solution is passed into an electrolytic cell wherein the alkali metal salt is converted to alkali metal hydroxide.

Abstract translation: 公开了一种用于降低流体中的硫浓度的方法，例如烃气流。 该方法包括使流体与碱金属氢氧化物水溶液接触，随后使得到的液体流出物与二氧化碳接触以形成碱金属碳酸盐水溶液和挥发性硫化合物。 将碱金属碳酸盐水溶液进入碱金属盐转化为碱金属氢氧化物的电解池中。

公开(公告)号：US2215617A

公开(公告)日：1940-09-24

申请号：US17090737

申请日：1937-10-25

Applicant: KEITH OWEN ORLANDO

Inventor： KEITH OWEN ORLANDO

IPC: E04F21/30

CPC classification number: E04F21/30

公开(公告)号：US08053230B2

公开(公告)日：2011-11-08

申请号：US11846193

申请日：2007-08-28

Applicant: Keith Owen Whittlinger

Inventor： Keith Owen Whittlinger

IPC: C12M1/22

CPC classification number: B01L3/5085 ,  B01L9/50 ,  B01L2300/021 ,  B01L2300/048 ,  B01L2400/086 ,  C12M23/10 ,  C12M23/34 ,  C12M23/38 ,  C12M27/20

Abstract: A device for culturing cells or tissue includes a culture dish with a bottom wall and at least one sidewall to define an interior cavity, at least one channel formed on the bottom wall to minimize the effect of fluid movement on biologics in the dish and, optionally, at least one barrier wall for partitioning the interior cavity into a plurality of compartments. The barrier wall maintains a biologic in one compartment separate from a biologic in another compartment. The barrier wall may also provide fluid communication between compartments.

Abstract translation: 用于培养细胞或组织的装置包括具有底壁和至少一个侧壁以限定内部空腔的培养皿，形成在底壁上的至少一个通道，以最小化流体对盘中生物制品的影响，以及任选地 至少一个阻挡壁，用于将内腔分隔成多个隔室。 隔离墙在一个隔间内保持生物体，与另一隔室中的生物分离。 阻隔壁还可以在隔室之间提供流体连通。

公开(公告)号：US20110169331A1

公开(公告)日：2011-07-14

申请号：US13073561

申请日：2011-03-28

Applicant: Jaspal GILL ,  David Keith Owen ,  Troy Sheets ,  Daniel Lewis Kline

Inventor： Jaspal GILL ,  David Keith Owen ,  Troy Sheets ,  Daniel Lewis Kline

IPC: H02J1/00

CPC classification number: G06F13/4081 ,  H02J1/04 ,  Y10T307/383 ,  Y10T307/406 ,  Y10T307/696 ,  Y10T307/702 ,  Y10T307/707

Abstract: A system may include a module that includes a component, a logic device to provide an instruction on behalf of the component, and control logic to generate a desired output voltage signal in response to a constant current, where the desired output voltage signal indicates a determined voltage that the component is configured to operate with when performing an operation. The system may include a board that includes a power supply to produce the determined voltage based on the instruction, and an interface to couple the determined voltage to the component to allow the component to perform the operation on behalf of the board, send the constant current to the control logic, and receive the desired output voltage signal from the control logic.

Abstract translation: 系统可以包括模块，其包括组件，用于代表组件提供指令的逻辑设备，以及响应于恒定电流产生期望的输出电压信号的控制逻辑，其中期望的输出电压信号指示确定的 该组件被配置为在执行操作时操作的电压。 该系统可以包括一个电路板，它包括一个基于该指令产生确定的电压的电源，以及一个用于将所确定的电压耦合到该组件以允许该组件代表该电路板执行该操作的接口，发送恒定电流 到控制逻辑，并从控制逻辑接收所需的输出电压信号。

公开(公告)号：US20090054221A1

公开(公告)日：2009-02-26

申请号：US12195671

申请日：2008-08-21

Applicant: Peter Kevin Baird ,  John David DeLorme ,  Keith Owen Whittlinger

Inventor： Peter Kevin Baird ,  John David DeLorme ,  Keith Owen Whittlinger

IPC: B04B7/06

CPC classification number: B01L3/50825 ,  B01L3/5021 ,  B04B5/0414

Abstract: A closure for attachment to a centrifuge bottle. The closure comprises an end wall and a sidewall extending from the end wall. The sidewall comprises a first terminal end, a second terminal end, a first transition surface, and a second transition surface. The first terminal end has a first outer peripheral boundary at a first radial distance from an axial centerline. The second terminal end has a second outer peripheral boundary at a second radial distance from the axial centerline. The second radial distance is less than the first radial distance. The first transition surface extends between the first outer peripheral boundary and the second transition surface. The second transition surface extends between the first transition surface and the second outer peripheral boundary.

Abstract translation: 用于连接到离心机瓶的封闭件。 封闭件包括端壁和从端壁延伸的侧壁。 侧壁包括第一终端，第二终端，第一过渡表面和第二过渡表面。 第一终端具有从轴向中心线开始的第一径向距离处的第一外围边界。 第二终端在离轴心中心线的第二径向距离处具有第二外周边界。 第二径向距离小于第一径向距离。 第一过渡表面在第一外围边界和第二过渡表面之间延伸。 第二过渡表面在第一过渡表面和第二外围边界之间延伸。

公开(公告)号：US20050200318A1

公开(公告)日：2005-09-15

申请号：US11127975

申请日：2005-05-11

Applicant: Mark Hunt ,  Keith Owen ,  Michael Hughes

Inventor： Mark Hunt ,  Keith Owen ,  Michael Hughes

IPC: F21S8/00 ,  H05B37/02 ,  G05B11/01 ,  G03C1/46 ,  H05B37/00 ,  H05B39/00 ,  H05B41/00

CPC classification number: H05B37/029 ,  F21V11/10 ,  F21W2131/406

Abstract: A stage lighting lamp unit includes a processor for receiving control data from a remote console. Beam orientation data for the lamp unit is passed to the lamp in the form of the x, y and z co-ordinates of a point in space through which the beam is to pass. The processor divides the required lamp travel into a number of stages dependent on execution duration data sent with the position data, and calculates, for each stage, a new value for pan and tilt angles for the lamp. These values are passed to pan and tilt controlling co-processors which control servo-motors for pan and tilt operation. The lamp unit also incorporates a rotatable shutter for interrupting the lamp beam when required. The shutters of all the lamps in a system can be instructed from the remote console to open and close in synchronism, thereby providing a stroboscopic effect.

Abstract translation: 舞台灯具单元包括用于从远程控制台接收控制数据的处理器。 灯单元的光束取向数据以光束通过的空间点的x，y和z坐标的形式传递到灯。 处理器根据与位置数据一起发送的执行持续时间数据将所需的灯行程划分为多个阶段，并为每个阶段计算灯的平移和倾斜角的新值。 这些值被传递给控制协调处理器，用于控制伺服电机进行摇摄和倾斜操作。 灯单元还包括可旋转的快门，用于在需要时中断灯光束。 系统中所有灯的快门可以从远程控制台指示同步打开和关闭，从而提供频闪效果。