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公开(公告)号：US20110217356A1
公开(公告)日：2011-09-08
申请号：US13042126
申请日：2011-03-07
IPC分类号： A61K9/70 , A61K9/00 , A61K38/00 , A61K39/395 , A61K38/18 , A61K31/497
CPC分类号： C07K14/4741 , A61L15/32 , A61L15/44 , A61L15/60 , A61L27/227 , A61L27/52 , A61L27/54 , A61L2300/252 , A61L2300/256 , A61L2300/406 , A61L2300/414 , C08L89/04
摘要： Provided herein are keratin compositions (e.g., keratin gels, scaffolds, particulates, and the like) including a compound of interest, useful for release and/or delivery of the compound of interest (e.g., in vivo or in vitro). In some embodiments, the composition is a composition formulated for controlled release of the compound of interest.
摘要翻译： 本文提供了包括可用于释放和/或递送目标化合物（例如体内或体外）的目的化合物的角蛋白组合物（例如，角蛋白凝胶，支架，颗粒等）。 在一些实施方案中，组合物是配制用于感兴趣化合物的受控释放的组合物。
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公开(公告)号：US20140127308A1
公开(公告)日：2014-05-08
申请号：US14002504
申请日：2012-02-21
CPC分类号： A61K35/54 , A61K9/167 , A61K9/5036 , A61K9/5073 , A61K31/565 , A61K31/57 , A61K2300/00
摘要： A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
摘要翻译： 描述了包含微胶囊的组合物，包含活哺乳动物卵巢颗粒细胞和活哺乳动物卵巢细胞的微胶囊。 在一些实施方案中，颗粒细胞和细胞被包含在组合物中的分离的微胶囊中; 在一些实施方案中，颗粒细胞和细胞在组合物中一起包含在相同的微胶囊中。组合物可用于雌激素，并且任选地也可用于孕酮，递送，因此优选是游离的或基本上不含卵母细胞。 还描述了使用它们的方法和含有它们的药物制剂。
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公开(公告)号：US09283251B2
公开(公告)日：2016-03-15
申请号：US14002504
申请日：2012-02-21
CPC分类号： A61K35/54 , A61K9/167 , A61K9/5036 , A61K9/5073 , A61K31/565 , A61K31/57 , A61K2300/00
摘要： A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
摘要翻译： 描述了包含微胶囊的组合物，包含活哺乳动物卵巢颗粒细胞和活哺乳动物卵巢细胞的微胶囊。 在一些实施方案中，颗粒细胞和细胞被包含在组合物中的分离的微胶囊中; 在一些实施方案中，颗粒细胞和细胞在组合物中一起包含在相同的微胶囊中。组合物可用于雌激素，并且任选地也可用于孕酮，递送，因此优选是游离的或基本上不含卵母细胞。 还描述了使用它们的方法和含有它们的药物制剂。
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公开(公告)号：US10434213B2
公开(公告)日：2019-10-08
申请号：US13042126
申请日：2011-03-07
IPC分类号： A61L27/18 , A61L15/26 , C08L89/04 , A61L15/44 , A61L15/60 , A61L27/52 , A61L27/54 , C07K14/47
摘要： Provided herein are keratin compositions (e.g., keratin gels, scaffolds, particulates, and the like) including a compound of interest, useful for release and/or delivery of the compound of interest (e.g., in vivo or in vitro). In some embodiments, the composition is a composition formulated for controlled release of the compound of interest.
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