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Patent Agency Ranking
公开(公告)号：US20120010139A1
公开(公告)日：2012-01-12
申请号：US13172776
申请日：2011-06-29
Applicant: Shen-Hua Peng , Hsin-Hsin Shen , Liang-Yo Yang , Meng-Yow Hsieh , Pei-Shan Li , Wei-Lin Yu , Tsai-Yu Lin , Po-Liang Lai , Jui-Sheng Sun , Chih-Hung Chang , Yi-Hung Lin
Inventor： Shen-Hua Peng , Hsin-Hsin Shen , Liang-Yo Yang , Meng-Yow Hsieh , Pei-Shan Li , Wei-Lin Yu , Tsai-Yu Lin , Po-Liang Lai , Jui-Sheng Sun , Chih-Hung Chang , Yi-Hung Lin
CPC classification number: A61L27/50 , A61L27/18 , A61L27/54 , A61L27/58 , A61L2300/414 , A61L2430/02
Abstract: Thermal responsive compositions for treating bone diseases are provided. The thermal responsive composition for treating bone diseases includes a bone growth factor and a biodegradable copolymer. The biodegradable copolymer has a structure of Formula (I) or Formula (II): A-B-BOX-B-A (Formula I) and B-A-B-(BOX-B-A-B)n-BOX-B-A-B Formula (II), wherein, A includes a hydrophilic polyethylene glycol polymer, B includes a hydrophobic polyester polymer, BOX is a bifunctional group monomer of 2,2′-Bis(2-oxazoline) and used for coupling the blocks A-B or B-A-B, and n is an integer and the same or more than 0.
Abstract translation: 提供了用于治疗骨疾病的热应答组合物。 用于治疗骨疾病的热应答组合物包括骨生长因子和可生物降解的共聚物。 生物降解性共聚物具有式（I）或式（II）的结构：AB-BOX-BA（式I）和BAB-（BOX-BAB）n-BOX-BAB式（II），其中，A包括亲水 聚乙二醇聚合物，B包括疏水性聚酯聚合物，BOX是2,2'-双（2-恶唑啉）的双官能团单体，用于偶联嵌段AB或BAB，并且n为整数并且相同或多于 0。
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公开(公告)号：US08062372B2
公开(公告)日：2011-11-22
申请号：US11611821
申请日：2006-12-15
Applicant: Yang-Hwei Tsuang , Jui-Sheng Sun , Chun-Jen Liao , Chen-Chi Tsai , Shan-Chang Chueh , Yi-Hung Lin , Shian-Yih Wang , I-Fan Chiu
Inventor： Yang-Hwei Tsuang , Jui-Sheng Sun , Chun-Jen Liao , Chen-Chi Tsai , Shan-Chang Chueh , Yi-Hung Lin , Shian-Yih Wang , I-Fan Chiu
IPC: A61F2/44
CPC classification number: A61F2/4455 , A61F2/30771 , A61F2002/2835 , A61F2002/3008 , A61F2002/30153 , A61F2002/30163 , A61F2002/30171 , A61F2002/30772 , A61F2002/4629 , A61F2230/0019 , A61F2230/0028 , A61F2230/005 , A61F2250/0098 , A61F2310/00179 , A61F2310/00365
Abstract: A spinal fusion device abutting and fixed between adjacent vertebrae. The spinal fusion device includes a support frame. The support frame has a plurality of extending bodies, each radially extending from a center of the support frame. A predetermined gap exists between every two adjacent extending bodies, receiving a bone graft.
Abstract translation: 脊椎融合装置邻接并固定在相邻的椎骨之间。 脊柱融合装置包括支撑框架。 支撑框架具有多个延伸体，每个延伸体从支撑框架的中心径向延伸。 在每两个相邻的延伸体之间存在预定的间隙，接收骨移植物。
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公开(公告)号：US20070156240A1
公开(公告)日：2007-07-05
申请号：US11611821
申请日：2006-12-15
Applicant: Yang-Hwei Tsuang , Jui-Sheng Sun , Chun-Jen Liao , Chen-Chi Tsai , Shan-Chang Chueh , Yi-Hung Lin , Shian-Yih Wang , I-Fan Chiu
Inventor： Yang-Hwei Tsuang , Jui-Sheng Sun , Chun-Jen Liao , Chen-Chi Tsai , Shan-Chang Chueh , Yi-Hung Lin , Shian-Yih Wang , I-Fan Chiu
IPC: A61F2/44
CPC classification number: A61F2/4455 , A61F2/30771 , A61F2002/2835 , A61F2002/3008 , A61F2002/30153 , A61F2002/30163 , A61F2002/30171 , A61F2002/30772 , A61F2002/4629 , A61F2230/0019 , A61F2230/0028 , A61F2230/005 , A61F2250/0098 , A61F2310/00179 , A61F2310/00365
Abstract: A spinal fusion device abutting and fixed between adjacent vertebrae. The spinal fusion device includes a support frame. The support frame has a plurality of extending bodies, each radially extending from a center of the support frame. A predetermined gap exists between every two adjacent extending bodies, receiving a bone graft.
Abstract translation: 脊椎融合装置邻接并固定在相邻的椎骨之间。 脊柱融合装置包括支撑框架。 支撑框架具有多个延伸体，每个延伸体从支撑框架的中心径向延伸。 在每两个相邻的延伸体之间存在预定的间隙，接收骨移植物。
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公开(公告)号：US08614190B2
公开(公告)日：2013-12-24
申请号：US13172776
申请日：2011-06-29
Applicant: Shen-Hua Peng , Hsin-Hsin Shen , Liang-Yo Yang , Meng-Yow Hsieh , Pei-Shan Li , Wei-Lin Yu , Tsai-Yu Lin , Po-Liang Lai , Jui-Sheng Sun , Chih-Hung Chang , Yi-Hung Lin
Inventor： Shen-Hua Peng , Hsin-Hsin Shen , Liang-Yo Yang , Meng-Yow Hsieh , Pei-Shan Li , Wei-Lin Yu , Tsai-Yu Lin , Po-Liang Lai , Jui-Sheng Sun , Chih-Hung Chang , Yi-Hung Lin
IPC: A61P19/08 , A61K38/18 , A61K31/74 , C07K14/51 , C07K14/475
CPC classification number: A61L27/50 , A61L27/18 , A61L27/54 , A61L27/58 , A61L2300/414 , A61L2430/02
Abstract: Thermal responsive compositions for treating bone diseases are provided. The thermal responsive composition for treating bone diseases includes a bone growth factor and a biodegradable copolymer. The biodegradable copolymer has a structure of Formula (I) or Formula (II): A-B-BOX-B-A Formula (I) B-A-B-(BOX-B-A-B)n-BOX-B-A-B Formula (II) wherein, A includes a hydrophilic polyethylene glycol polymer, B includes a hydrophobic polyester polymer, BOX is a bifunctional group monomer of 2, 2′-Bis(2-oxazoline) and used for coupling the blocks A-B or B-A-B, and n is an integer and the same or more than 0.
Abstract translation: 提供了用于治疗骨疾病的热应答组合物。 用于治疗骨疾病的热应答组合物包括骨生长因子和可生物降解的共聚物。 生物降解性共聚物具有式（I）或式（II）的结构：AB-BOX-B-AFormula（I）BAB-（BOX-BAB）n-BOX-BA-BFormula（II）其中，A包括亲水 聚乙二醇聚合物，B包括疏水性聚酯聚合物，BOX是2,2'-双（2-恶唑啉）的双官能团单体，用于偶联嵌段AB或BAB，并且n是整数并且相同或多于 0。
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公开(公告)号：US20080075701A1
公开(公告)日：2008-03-27
申请号：US11525333
申请日：2006-09-21
Applicant: Chin-Yih Rex Hong , Herng-Er Horng , Jui-Sheng Sun , Hong-Chang Yang , Shieh-Yueh Yang
Inventor： Chin-Yih Rex Hong , Herng-Er Horng , Jui-Sheng Sun , Hong-Chang Yang , Shieh-Yueh Yang
CPC classification number: A61K48/00
Abstract: A composition for magnetofecting genetic materials into cells with the assistant of an external magnetic force is described. The composition includes hydrophilic vectors, magnetic nanoparticles, and genetic materials, wherein the magnetic nanoparticles and the genetic materials are enveloped inside the hydrophilic vectors.
Abstract translation: 描述了用外部磁力辅助将遗传物质磁化成细胞的组合物。 组合物包括亲水载体，磁性纳米颗粒和遗传物质，其中磁性纳米颗粒和遗传物质被包封在亲水载体内。
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