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1.发明授权Materials and methods for preparation of alkaline earth ferrates from alkaline earth oxides, peroxides, and nitrates 有权从碱土氧化物，过氧化物和硝酸盐制备碱土金属铁酸盐的材料和方法公开(公告)号：US08372441B2
公开(公告)日：2013-02-12
申请号：US12627900
申请日：2009-11-30
申请人： John Alfred Thompson , John Hen
发明人： John Alfred Thompson , John Hen
CPC分类号： C01G49/0036 , A61K33/26 , A61K33/40 , A61L15/18 , A61L2400/04
摘要： The subject invention concerns methods for preparing alkaline earth ferrates and the preparation of hemostatic compositions from alkaline earth ferrates. In one embodiment, the alkaline earth ferrate is strontium ferrate. In one embodiment, methods of the invention comprise heat treating mixtures of alkaline earth oxides and/or peroxides with iron oxides, such as hematite or magnetite. The subject invention also concerns hemostatic compositions produced using metallic oxides that are reacted with alkaline earth oxides and/or peroxides and the methods used to produce the hemostatic compositions.
摘要翻译： 本发明涉及制备碱土金属铁酸盐的方法和由碱土金属铁酸盐制备止血组合物。 在一个实施方案中，碱土金属高铁酸盐是高铁酸锶。 在一个实施方案中，本发明的方法包括将碱土金属氧化物和/或过氧化物的混合物与铁氧化物如赤铁矿或磁铁矿加热处理。 本发明还涉及使用与碱土金属氧化物和/或过氧化物反应的金属氧化物制备的止血组合物以及用于制备止血组合物的方法。
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公开(公告)号：US20110020425A1
公开(公告)日：2011-01-27
申请号：US12924547
申请日：2010-09-29
CPC分类号： A61K33/26 , A61K31/715 , A61K31/717 , A61K31/718 , A61K31/722 , A61K31/729 , A61K31/731 , A61K31/734 , A61K31/74 , A61K31/79 , A61K33/00 , A61K33/06 , A61K33/24 , A61K33/32 , A61K33/34 , A61K33/38 , A61K45/06 , A61L15/18 , A61L15/44 , A61L2300/102 , A61L2300/104 , A61L2300/404
摘要： The subject invention pertains to methods and compositions for wound treatment. The methods and compositions provide for promoting and accelerating wound healing; provide for inhibition of microbial infection; provide for a protective scab-like covering on a wound; and/or for arresting the flow of blood or body fluids from an open wound. The methods and compositions can be used to increase granulation and epithelialization in a wound. In one embodiment, a substantially anhydrous compound of a salt ferrate and a cation exchange material is provided. Compositions of the invention can also include silver compounds. In use, compositions of the invention are preferably applied as a dry dressing to an exuding chronic wound site. If the chronic wound site is dry, the wound site may be wetted with a suitable liquid or aqueous media prior to applying the dressing in dry form.
摘要翻译： 本发明涉及伤口治疗的方法和组合物。 所述方法和组合物用于促进和加速伤口愈合; 提供抑制微生物感染; 在伤口上提供防护性的scab状覆盖物; 和/或用于阻止血液或体液从开口伤口流出。 方法和组合物可用于增加伤口中的造粒和上皮形成。 在一个实施方案中，提供了基本上无水的高铁酸盐和阳离子交换材料的化合物。 本发明的组合物还可以包括银化合物。 在使用中，优选将本发明的组合物作为干燥敷料施用于渗出性慢性伤口部位。 如果慢性伤口部位干燥，则在施用干燥形式的敷料之前，可以用合适的液体或水性介质润湿伤口部位。
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公开(公告)号：US08361504B2
公开(公告)日：2013-01-29
申请号：US12421300
申请日：2009-04-09
申请人： John Hen , John Alfred Thompson , Talmadge Kelly Keene , Michael H. Tollon , Mark Travi , Roger Thomas
发明人： John Hen , John Alfred Thompson , Talmadge Kelly Keene , Michael H. Tollon , Mark Travi , Roger Thomas
CPC分类号： A61L15/44 , A61L15/60 , A61L26/0066 , A61L26/008 , A61L2300/104 , A61L2300/404 , A61L2300/406 , A61L2300/602
摘要： The subject invention pertains to materials and methods for stopping or decreasing the blood flow from an open wound or medical or surgical procedure. Compositions of the invention comprise a salt form of a cross-linked polyacrylic acid. In one embodiment, the composition comprises a sodium salt of a polyacrylic acid. Compositions of the invention can also optionally comprise one or more different salt ferrates, and/or a cationic exchanger resins, and/or a silver compound. In an exemplified embodiment, a composition of the invention comprises sodium polyacrylate provided in a dry powdered form. Polyacrylate compositions of the invention can be applied directly to a wound or treatment site, or they can be incorporated into a wound dressing, such as a bandage. The clot or scab formed at a wound or treatment site treated with the present invention is extremely elastic and exhibits considerable tensile strength when stretched to the breaking point. The subject invention also concerns wound and surgical site dressings and coverings, and methods of using a composition of the invention to stop blood flow from an open wound or treatment site.
摘要翻译： 本发明涉及用于从开放伤口或医疗或手术过程中停止或减少血流的材料和方法。 本发明的组合物包含交联聚丙烯酸的盐形式。 在一个实施方案中，组合物包含聚丙烯酸的钠盐。 本发明的组合物还可任选地包含一种或多种不同的高铁酸盐，和/或阳离子交换树脂和/或银化合物。 在一个示例性实施方案中，本发明的组合物包含以干燥粉末形式提供的聚丙烯酸钠。 本发明的聚丙烯酸酯组合物可以直接施用到伤口或治疗部位，或者它们可以并入伤口敷料如绷带中。 在用本发明处理的伤口或治疗部位处形成的凝块或痂是非常有弹性的，并且当拉伸到断裂点时显示出显着的拉伸强度。 本发明还涉及伤口和手术部位敷料和覆盖物，以及使用本发明的组合物来阻止来自开放伤口或治疗部位的血液流动的方法。
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4.发明申请MATERIALS AND METHODS FOR PREPARATION OF ALKALINE EARTH FERRATES FROM ALKALINE EARTH OXIDES, PEROXIDES, AND NITRATES 有权碱性碱土金属氧化物，过氧化物和硝酸盐制备碱土金属盐的材料与方法公开(公告)号：US20100151049A1
公开(公告)日：2010-06-17
申请号：US12627900
申请日：2009-11-30
申请人： John Alfred Thompson , John Hen
发明人： John Alfred Thompson , John Hen
CPC分类号： C01G49/0036 , A61K33/26 , A61K33/40 , A61L15/18 , A61L2400/04
摘要： The subject invention concerns methods for preparing alkaline earth ferrates and the preparation of hemostatic compositions from alkaline earth ferrates. In one embodiment, the alkaline earth ferrate is strontium ferrate. In one embodiment, methods of the invention comprise heat treating mixtures of alkaline earth oxides and/or peroxides with iron oxides, such as hematite or magnetite. The subject invention also concerns hemostatic compositions produced using metallic oxides that are reacted with alkaline earth oxides and/or peroxides and the methods used to produce the hemostatic compositions.
摘要翻译： 本发明涉及制备碱土金属铁酸盐的方法和由碱土金属铁酸盐制备止血组合物。 在一个实施方案中，碱土金属高铁酸盐是高铁酸锶。 在一个实施方案中，本发明的方法包括将碱土金属氧化物和/或过氧化物的混合物与铁氧化物如赤铁矿或磁铁矿加热处理。 本发明还涉及使用与碱土金属氧化物和/或过氧化物反应的金属氧化物制备的止血组合物以及用于制备止血组合物的方法。
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公开(公告)号：US20090252799A1
公开(公告)日：2009-10-08
申请号：US12421300
申请日：2009-04-09
申请人： John Hen , John Alfred Thompson , Talmadge Kelly Keene , Michael H. Tollon , Mark Travi , Roger Thomas
发明人： John Hen , John Alfred Thompson , Talmadge Kelly Keene , Michael H. Tollon , Mark Travi , Roger Thomas
CPC分类号： A61L15/44 , A61L15/60 , A61L26/0066 , A61L26/008 , A61L2300/104 , A61L2300/404 , A61L2300/406 , A61L2300/602
摘要： The subject invention pertains to materials and methods for stopping or decreasing the blood flow from an open wound or medical or surgical procedure. Compositions of the invention comprise a salt form of a cross-linked polyacrylic acid. In one embodiment, the composition comprises a sodium salt of a polyacrylic acid. Compositions of the invention can also optionally comprise one or more different salt ferrates, and/or a cationic exchanger resins, and/or a silver compound. In an exemplified embodiment, a composition of the invention comprises sodium polyacrylate provided in a dry powdered form. Polyacrylate compositions of the invention can be applied directly to a wound or treatment site, or they can be incorporated into a wound dressing, such as a bandage. The clot or scab formed at a wound or treatment site treated with the present invention is extremely elastic and exhibits considerable tensile strength when stretched to the breaking point. The subject invention also concerns wound and surgical site dressings and coverings, and methods of using a composition of the invention to stop blood flow from an open wound or treatment site.
摘要翻译： 本发明涉及用于从开放伤口或医疗或手术过程中停止或减少血流的材料和方法。 本发明的组合物包含交联聚丙烯酸的盐形式。 在一个实施方案中，组合物包含聚丙烯酸的钠盐。 本发明的组合物还可任选地包含一种或多种不同的高铁酸盐，和/或阳离子交换树脂和/或银化合物。 在一个示例性实施方案中，本发明的组合物包含以干燥粉末形式提供的聚丙烯酸钠。 本发明的聚丙烯酸酯组合物可以直接施用到伤口或治疗部位，或者它们可以并入伤口敷料如绷带中。 在用本发明处理的伤口或治疗部位处形成的凝块或痂是非常有弹性的，并且当拉伸到断裂点时显示出显着的拉伸强度。 本发明还涉及伤口和手术部位敷料和覆盖物，以及使用本发明的组合物来阻止来自开放伤口或治疗部位的血液流动的方法。
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