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公开(公告)号:US08100979B2
公开(公告)日:2012-01-24
申请号:US12479402
申请日:2009-06-05
IPC分类号: A61F2/44
CPC分类号: A61B17/562 , A61F2/30721 , A61F2/34 , A61F2/38 , A61F2/3872 , A61F2/3877 , A61F2/389 , A61F2002/30535 , A61F2250/0058 , A61L27/18 , A61L2430/24 , C08G18/10 , C08G18/4854 , C08G18/61 , C08G18/69 , C08L75/04 , C08G18/32
摘要: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed and procured components, adapted for insertion and placement into the body and at the joint site. In a preferred embodiment, component(s) can be partially cured and generally formed ex vivo and further and further formed in vivo at the joint site to enhance conformance and improve long term performance. In another embodiment, a preformed balloon or composite material can be inserted into the joint site and filled with a flowable biomaterial in situ to conform to the joint site. In yet another embodiment, the preformed component(s) can be fully cured and formed ex vivo and optionally further fitted and secured at the joint site. Preformed components can be sufficiently pliant to permit insertion through a minimally invasive portal, yet resilient enough to substantially assume, or tend towards, the desired form in vivo with additional forming there as needed.
摘要翻译: 一种用于创建或修改整形外科关节磨损表面的方法和系统,涉及准备和使用一种或多种部分或完全预成型和采购的部件,适于插入和放置在身体和关节部位。 在一个优选的实施方案中,组分可以部分固化,并且通常在体外形式离体进一步形成并且在接合部位进一步形成,以增强一致性并改善长期性能。 在另一个实施方案中,预先形成的球囊或复合材料可以插入到关节部位中并且在原位填充可流动的生物材料以符合关节部位。 在另一个实施方案中,预成型组分可以完全固化并离体形成,并任选地进一步装配并固定在接头部位。 预成型组件可以足够柔顺以允许通过微创入口插入,但足够弹性足以基本上假设或倾向于体内所需的形式,并根据需要进一步形成。
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公开(公告)号:US20090276047A1
公开(公告)日:2009-11-05
申请号:US12435087
申请日:2009-05-04
IPC分类号: A61F2/44
CPC分类号: A61F2/442 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/30014 , A61F2002/30016 , A61F2002/30075 , A61F2002/30166 , A61F2002/30235 , A61F2002/30383 , A61F2002/30387 , A61F2002/30462 , A61F2002/3052 , A61F2002/30561 , A61F2002/30563 , A61F2002/30594 , A61F2002/30604 , A61F2002/30677 , A61F2002/30971 , A61F2002/444 , A61F2002/4627 , A61F2210/0061 , A61F2220/0025 , A61F2220/0075 , A61F2230/0028 , A61F2230/0069 , A61F2250/0018 , A61F2250/0019
摘要: A method and apparatus for repairing a damaged intervertebral disc nucleus in a minimally invasive manner utilizes a modular disc prosthesis preferably comprised of at least three modular segments and at least two rails that operably connect adjacent modular segments. In one embodiment, each modular segment includes a harder inner portion and a softer outer portion. Preferably, the rails operate to slidably connect and interlock adjacent modular segments. A stem portion of the rails that extends outside the periphery of the body of the prosthesis is removable after implantation such that the modular segments form an implanted unitary device that closely mimics the geometry of the disc nucleus cavity.
摘要翻译: 用于以微创方式修复损伤的椎间盘细胞核的方法和装置利用模块化椎间盘假体,优选地包括至少三个模块化区段和至少两个可操作地连接相邻模块区段的轨道。 在一个实施例中,每个模块化区段包括较硬的内部部分和较软的外部部分。 优选地,轨道操作以可滑动地连接和互锁相邻的模块段。 在植入之后延伸到假体本体周边之外的轨道的茎部分是可去除的,使得模块化部分形成与模腔细胞核的几何形状紧密相似的植入的整体装置。
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公开(公告)号:US07591853B2
公开(公告)日:2009-09-22
申请号:US11372477
申请日:2006-03-09
IPC分类号: A61F2/44
CPC分类号: A61F2/442 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/30014 , A61F2002/30016 , A61F2002/30075 , A61F2002/30166 , A61F2002/30235 , A61F2002/30383 , A61F2002/30387 , A61F2002/30462 , A61F2002/3052 , A61F2002/30561 , A61F2002/30563 , A61F2002/30594 , A61F2002/30604 , A61F2002/30677 , A61F2002/30971 , A61F2002/444 , A61F2002/4627 , A61F2210/0061 , A61F2220/0025 , A61F2220/0075 , A61F2230/0028 , A61F2230/0069 , A61F2250/0018 , A61F2250/0019
摘要: A method and apparatus for repairing a damaged intervertebral disc nucleus in a minimally invasive manner utilizes a modular disc prosthesis preferably comprised of at least three modular segments and at least two rails that operably connect adjacent modular segments. In one embodiment, each modular segment includes a harder inner portion and a softer outer portion. Preferably, the rails operate to slidably connect and interlock adjacent modular segments. A stem portion of the rails that extends outside the periphery of the body of the prosthesis is removable after implantation such that the modular segments form an implanted unitary device that closely mimics the geometry of the disc nucleus cavity.
摘要翻译: 用于以微创方式修复损伤的椎间盘细胞核的方法和装置利用模块化椎间盘假体,优选地包括至少三个模块化区段和至少两个可操作地连接相邻模块区段的轨道。 在一个实施例中,每个模块化区段包括较硬的内部部分和较软的外部部分。 优选地,轨道操作以可滑动地连接和互锁相邻的模块段。 在植入之后延伸到假体本体周边之外的轨道的茎部分是可去除的,使得模块化部分形成与模腔细胞核的几何形状紧密相似的植入的整体装置。
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公开(公告)号:US20080140206A1
公开(公告)日:2008-06-12
申请号:US11900205
申请日:2007-09-10
申请人: Jeffrey C. Felt
发明人: Jeffrey C. Felt
IPC分类号: A61F2/44
CPC分类号: A61F2/442 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/30014 , A61F2002/30016 , A61F2002/30075 , A61F2002/30166 , A61F2002/30235 , A61F2002/30383 , A61F2002/30387 , A61F2002/30462 , A61F2002/3052 , A61F2002/30561 , A61F2002/30563 , A61F2002/30594 , A61F2002/30604 , A61F2002/30677 , A61F2002/30971 , A61F2002/444 , A61F2002/4627 , A61F2210/0061 , A61F2220/0025 , A61F2220/0075 , A61F2230/0028 , A61F2230/0069 , A61F2250/0018 , A61F2250/0019
摘要: A method and apparatus for repairing a damaged intervertebral disc nucleus in a minimally invasive manner utilizes a modular disc prosthesis. The modular disc prosthesis preferably comprises at least three modular segments. In one embodiment, each modular segment includes an inner core and an outer shell. The modular segments are selectively interlockable in situ with each other. The modular segments form an implanted unitary device that closely mimics the geometry of the disc nucleus cavity.
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公开(公告)号:US07766965B2
公开(公告)日:2010-08-03
申请号:US11428120
申请日:2006-06-30
IPC分类号: A61F2/44
CPC分类号: C08G18/4854 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/17 , A61B17/7097 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30756 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/3008 , A61F2002/30235 , A61F2002/30563 , A61F2002/30578 , A61F2002/30583 , A61F2002/30601 , A61F2002/30841 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/444 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61F2250/0098 , A61L27/18 , A61L29/041 , A61L29/06 , A61L2430/38 , B01F2215/0039 , C08G18/10 , C08G18/69 , Y10S606/907 , Y10S606/91 , C08L83/04 , C08L75/04 , C08L23/00 , C08L67/02 , C08G18/3206
摘要: A method of treating a diseased or damaged intervertebral disc having a nucleus pulposus and an annulus. The method includes the steps of accessing and preparing the intervertebral disc for receipt of the biomaterial by removing at least a portion of the nucleus pulposus to create a nuclear cavity. A quantity of the curable biomaterial is delivered under pressure to the nuclear cavity. The delivered biomaterial is at least partially cured in such a manner to retain it in the nuclear cavity. The at least partially cured biomaterial is contoured to achieve a desired conformation approximating that of the nuclear cavity.
摘要翻译: 一种治疗患有或受损的具有髓核和环的椎间盘的方法。 该方法包括以下步骤:通过去除髓核的至少一部分以产生核腔来获取和准备用于接收生物材料的椎间盘。 一定量的可固化生物材料在压力下输送到核腔。 递送的生物材料至少部分地固化以将其保持在核腔中。 所述至少部分固化的生物材料的轮廓是实现与核腔近似的所需构型。
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公开(公告)号:US07713301B2
公开(公告)日:2010-05-11
申请号:US11277887
申请日:2006-03-29
IPC分类号: A61F2/44
CPC分类号: C08G18/4854 , A61B1/00165 , A61B17/00234 , A61B17/16 , A61B17/17 , A61B17/7097 , A61B2017/00535 , A61F2/07 , A61F2/28 , A61F2/30756 , A61F2/30767 , A61F2/3099 , A61F2/32 , A61F2/38 , A61F2/4081 , A61F2/4202 , A61F2/441 , A61F2/442 , A61F2/4601 , A61F2/4611 , A61F2/82 , A61F2/945 , A61F2002/30016 , A61F2002/30024 , A61F2002/3008 , A61F2002/30235 , A61F2002/30563 , A61F2002/30578 , A61F2002/30583 , A61F2002/30601 , A61F2002/30841 , A61F2002/30929 , A61F2002/30957 , A61F2002/4233 , A61F2002/444 , A61F2002/4627 , A61F2002/4635 , A61F2210/0085 , A61F2230/0069 , A61F2250/0019 , A61F2250/0021 , A61F2250/0098 , A61L27/18 , A61L29/041 , A61L29/06 , A61L2430/38 , B01F2215/0039 , C08G18/10 , C08G18/69 , Y10S606/907 , Y10S606/91 , C08L83/04 , C08L75/04 , C08L23/00 , C08L67/02 , C08G18/3206
摘要: A system for repairing an intervertebral disc by delivering and curing a biomaterial in situ within the disc. The system includes both a device, having an insertable balloon and related lumen, controls and adapters, as well as an in situ curable biomaterial (and related biomaterial delivery means). The system can allow the doctor to determine a suitable endpoint for biomaterial delivery, by controlling distraction and/or biomaterial delivery pressure, and in turn, to deliver a desired quantity of biomaterial to the balloon in order to achieve improved polymer cure and implant characteristics. Also provided is a related method for repairing an intervertebral disc by using such a system to deliver and cure the biomaterial in situ. The system can be used to implant a prosthetic total disc, or a prosthetic disc nucleus in a manner that leaves the surrounding disc tissue substantially intact.
摘要翻译: 一种通过在盘内原位递送和固化生物材料来修复椎间盘的系统。 该系统包括具有可插入球囊和相关内腔的装置,对照和适配器,以及原位可固化生物材料(和相关的生物材料递送装置)。 该系统可以允许医生通过控制牵引和/或生物材料输送压力来确定用于生物材料递送的合适的终点,并且反过来,将气体中所需量的生物材料输送到气囊中,以实现改进的聚合物固化和植入特征。 还提供了一种通过使用这种系统来原位递送和固化生物材料来修复椎间盘的相关方法。 该系统可以用于以使得周围的盘组织基本上完整的方式植入假体总盘或假体椎间盘细胞核。
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公开(公告)号:US20080234820A1
公开(公告)日:2008-09-25
申请号:US11953203
申请日:2007-12-10
申请人: Jeffrey C. Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
发明人: Jeffrey C. Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
CPC分类号: A61B17/562 , A61F2/30721 , A61F2/34 , A61F2/38 , A61F2/3872 , A61F2/3877 , A61F2/389 , A61F2002/30535 , A61F2250/0058 , A61L27/18 , A61L2430/24 , C08G18/10 , C08G18/4854 , C08G18/61 , C08G18/69 , C08L75/04 , C08G18/32
摘要: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed and procured components, adapted for insertion and placement into the body and at the joint site. In a preferred embodiment, component(s) can be partially cured and generally formed ex vivo and further and further formed in vivo at the joint site to enhance conformance and improve long term performance. In another embodiment, a preformed balloon or composite material can be inserted into the joint site and filled with a flowable biomaterial in situ to conform to the joint site. In yet another embodiment, the preformed component(s) can be fully cured and formed ex vivo and optionally further fitted and secured at the joint site. Preformed components can be sufficiently pliant to permit insertion through a minimally invasive portal, yet resilient enough to substantially assume, or tend towards, the desired form in vivo with additional forming there as needed.
摘要翻译: 一种用于创建或修改整形外科关节磨损表面的方法和系统,涉及准备和使用一种或多种部分或完全预成型和采购的部件,适于插入和放置在身体和关节部位。 在一个优选的实施方案中,组分可以部分固化,并且通常在体外形式离体进一步形成并且在接合部位进一步形成,以增强一致性并改善长期性能。 在另一个实施方案中,预先形成的球囊或复合材料可以插入到关节部位中并且在原位填充可流动的生物材料以符合关节部位。 在另一个实施方案中,预成型组分可以完全固化并离体形成,并任选地进一步装配并固定在接头部位。 预成型组件可以足够柔顺以允许通过微创入口插入,但足够弹性足以基本上假设或倾向于体内所需的形式,并根据需要进一步形成。
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公开(公告)号:US07320709B2
公开(公告)日:2008-01-22
申请号:US10722019
申请日:2003-11-24
申请人: Jeffrey C. Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
发明人: Jeffrey C. Felt , Mark A. Rydell , Paul J. Buscemi , Alexander Arsenyev , Christopher H. Porter
CPC分类号: A61B17/562 , A61F2/30721 , A61F2/34 , A61F2/38 , A61F2/3872 , A61F2/3877 , A61F2/389 , A61F2002/30535 , A61F2250/0058 , A61L27/18 , A61L2430/24 , C08G18/10 , C08G18/4854 , C08G18/61 , C08G18/69 , C08L75/04 , C08G18/32
摘要: A method and system for the creation or modification of the wear surface of orthopedic joints, involving the preparation and use of one or more partially or fully preformed and procured components, adapted for insertion and placement into the body and at the joint site. In a preferred embodiment, component(s) can be partially cured and generally formed ex vivo and further and further formed in vivo at the joint site to enhance conformance and improve long term performance. In another embodiment, a preformed balloon or composite material can be inserted into the joint site and filled with a flowable biomaterial in situ to conform to the joint site. In yet another embodiment, the preformed component(s) can be fully cured and formed ex vivo and optionally further fitted and secured at the joint site. Preformed components can be sufficiently pliant to permit insertion through a minimally invasive portal, yet resilient enough to substantially assume, or tend towards, the desired form in vivo with additional forming there as needed.
摘要翻译: 一种用于创建或修改整形外科关节磨损表面的方法和系统,涉及准备和使用一种或多种部分或完全预成型和采购的部件,适于插入和放置在身体和关节部位。 在一个优选的实施方案中,组分可以部分固化,并且通常在体外形式离体进一步形成并且在接合部位进一步形成,以增强一致性并改善长期性能。 在另一个实施方案中,预先形成的球囊或复合材料可以插入到关节部位中并且在原位填充可流动的生物材料以符合关节部位。 在另一个实施方案中,预成型组分可以完全固化并离体形成,并任选地进一步装配并固定在接头部位。 预成型组件可以足够柔顺以允许通过微创入口插入,但足够弹性足以基本上假设或倾向于体内所需的形式,并根据需要进一步形成。
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公开(公告)号:US07267690B2
公开(公告)日:2007-09-11
申请号:US11372357
申请日:2006-03-09
申请人: Jeffrey C. Felt
发明人: Jeffrey C. Felt
IPC分类号: A61F2/44
CPC分类号: A61F2/442 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/30014 , A61F2002/30016 , A61F2002/30075 , A61F2002/30166 , A61F2002/30235 , A61F2002/30383 , A61F2002/30387 , A61F2002/30462 , A61F2002/3052 , A61F2002/30561 , A61F2002/30563 , A61F2002/30594 , A61F2002/30604 , A61F2002/30677 , A61F2002/30971 , A61F2002/444 , A61F2002/4627 , A61F2210/0061 , A61F2220/0025 , A61F2220/0075 , A61F2230/0028 , A61F2230/0069 , A61F2250/0018 , A61F2250/0019
摘要: A method and apparatus for repairing a damaged intervertebral disc nucleus in a minimally invasive manner utilizes a modular disc prosthesis. The modular disc prosthesis preferably comprises at least three modular segments. In one embodiment, each modular segment includes an inner core and an outer shell. The modular segments are selectively interlockable in situ with each other. The modular segments form an implanted unitary device that closely mimics the geometry of the disc nucleus cavity.
摘要翻译: 用于以微创方式修复受损的椎间盘细胞核的方法和装置利用模块化椎间盘假体。 模块化椎间盘假体优选地包括至少三个模块部分。 在一个实施例中,每个模块化区段包括内芯和外壳。 模块化部分可以选择性地互相啮合。 模块化部分形成了一种植入的整体装置,其紧密地模仿了椎间盘细胞腔的几何形状。
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公开(公告)号:US06443988B1
公开(公告)日:2002-09-03
申请号:US09193973
申请日:1998-11-18
IPC分类号: A61F244
摘要: A method, and related composition and apparatus for repairing a tissue site. The method involves the use of a curable polyurethane biomaterial composition having a plurality of parts adapted to be mixed at the time of use in order to provide a flowable composition and to initiate cure. The flowable composition can be delivered using minimally invasive means to a tissue site and there fully cured provide a permanent and biocompatible prosthesis for repair of the tissue site. Further provided are a mold apparatus, e.g., in the form of a balloon or tubular cavity, for receiving a biomaterial composition, and a method for delivering and filling the mold apparatus with a curable composition in situ to provide a prosthesis for tissue repair.
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