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    Ophthalmic fluid reservoir assembly for use with an ophthalmic fluid delivery device
    2.
    发明授权
    Ophthalmic fluid reservoir assembly for use with an ophthalmic fluid delivery device 有权
    用于眼科流体输送装置的眼液储存器组件

    公开(公告)号：US08545463B2

    公开(公告)日：2013-10-01

    申请号：US11698647

    申请日：2007-01-26

    申请人： James F. Collins, Jr. ,  Michael Joseph Jobin

    发明人： James F. Collins, Jr. ,  Michael Joseph Jobin

    IPC分类号： A61M11/00

    CPC分类号： A61M11/005 ,  A61F9/0008 ,  A61M11/041 ,  A61M11/044 ,  A61M11/065 ,  A61M2202/04 ,  A61M2205/18 ,  A61M2205/3386 ,  A61M2205/3653 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/59 ,  A61M2205/8212 ,  A61M2210/0612

    摘要： A reservoir assembly for use in an ophthalmic fluid delivery device adapted to deliver an ophthalmic fluid in the form of a mist to an ocular region of a patient is provided, wherein the device has a lumen-defining component configured to deliver the fluid from the reservoir assembly. The reservoir assembly includes a reservoir defining an aperture and a cavity in fluid flow communication with the aperture, a fluid contained in the cavity of the reservoir, and a gasket traversing the aperture. The gasket defines a passage configured to receive a portion of the lumen-defining component and to permit the flow of the fluid from the cavity and through the aperture when the portion of the lumen-defining component is inserted through the passage. The gasket is also configured to substantially prevent the flow of the fluid from the cavity and through the aperture when the portion of the lumen-defining component is not inserted through the passage.

    摘要翻译： 提供了一种用于眼科流体输送装置的储存器组件，其适于将雾状形式的眼用液输送到患者的眼部区域，其中，所述装置具有内腔限定部件，其被构造成将流体从所述储存器 部件。 储存器组件包括限定孔的储存器和与孔隙流体流动连通的空腔，容纳在储存器的空腔中的流体和穿过孔的垫圈。 垫圈限定通道，该通道构造成接收管腔限定部件的一部分，并且当内腔限定部件的部分插入穿过通道时，允许流体从腔体流过孔。 垫圈还构造成当内腔限定部件的部分未插入穿过通道时，基本上防止流体从腔体流过孔。

    Ophthalmic fluid delivery system
    3.
    发明申请
    Ophthalmic fluid delivery system 有权
    眼科输液系统

    公开(公告)号：US20090149829A1

    公开(公告)日：2009-06-11

    申请号：US12287147

    申请日：2008-10-06

    申请人： James F. Collins, JR.

    发明人： James F. Collins, JR.

    IPC分类号： A61F9/00

    CPC分类号： B05B17/0646 ,  A61F9/0008 ,  A61M11/005 ,  A61M11/041 ,  A61M11/042 ,  A61M11/065 ,  A61M2205/59 ,  A61M2210/0612 ,  B05B17/0623 ,  B05B17/0676

    摘要： A method of safely delivering an ophthalmic fluid to an eye, the method including targeting the eye with an ophthalmic fluid misting device and activating an ultrasonic generator to deliver the ophthalmic fluid from the ophthalmic fluid misting device across a space between the misting device and the eye. The method further including maintaining a momentum of the ophthalmic fluid that is insufficient to trigger at least one of the ocular blink reflex and the lacrimation reflex of the eye.

    摘要翻译： 一种将眼液安全地递送到眼睛的方法，该方法包括用眼科液体雾化装置对眼睛进行瞄准，并激活超声波发生器以将眼科流体从眼科液体喷雾装置穿过雾化装置和眼睛之间的空间 。 所述方法还包括保持眼液的动量不足以触发眼睛眨眼反射和眼睛的流淌反射中的至少一种。

    Amino acid isomers, their production and their medicinal use
    4.
    发明授权
    Amino acid isomers, their production and their medicinal use 失效

    公开(公告)号：US4477391A

    公开(公告)日：1984-10-16

    申请号：US356036

    申请日：1982-03-08

    申请人： James F. Collins

    发明人： James F. Collins

    IPC分类号： C07F5/02 ,  A61K31/195 ,  A61K31/22 ,  A61K31/41 ,  A61P25/00 ,  A61P25/08 ,  C07C67/00 ,  C07C301/00 ,  C07C303/16 ,  C07C309/18 ,  C07D257/04 ,  C07F9/09 ,  C07F9/38 ,  C07F9/40

    CPC分类号： C07F9/3808 ,  C07F9/4006

    摘要： The (-)-D-isomers of compounds of the general formula ##STR1## in which X stands for an acidic radical, especially a radical of phosphonic acid, sulphonic acid, boronic acid or tetrazole,R stands for an alkylene, alkenylene or alkynylene radical with 3 or more carbon atoms, preferably 3 to 6 carbon atoms, or a C.sub.3 to C.sub.7 cycloalkyl radical, andA and B independently of each other stand for a hydrogen atom or a lipophilic radical, especially an ester radical,or salts thereof, or pharmaceutically acceptable bioprecursors thereof, especially (-)-D-aminophosphonopentanoic acid and (-)-D-aminophosphonoheptanoic acid, find use in the treatment of diseases of the central nervous system.The compound aminophosphonoheptanoic acid is also novel as a racemic mixture and the present invention also relates to that compound in racemic form which may be used in the same way as the said (-)-D-isomers.

    Wheel mass damper assembly
    5.
    发明授权
    Wheel mass damper assembly 有权
    车轮质量阻尼器组件

    公开(公告)号：US08579311B2

    公开(公告)日：2013-11-12

    申请号：US13105975

    申请日：2011-05-12

    申请人： Albert H. Butlin, Jr. ,  Vincent A. Bommarito ,  James F. Collins

    发明人： Albert H. Butlin, Jr. ,  Vincent A. Bommarito ,  James F. Collins

    IPC分类号： B60G15/00

    CPC分类号： B60G3/01 ,  B60G3/20 ,  B60G13/16 ,  B60G15/06 ,  B60G2200/144 ,  F16F9/182 ,  F16F9/20

    摘要： A damper mass damper assembly includes a rod, and a casing disposed annularly about the rod and defining a primary fluid chamber therebetween. The rod includes an annular wall that defines a first and a second expansion chamber disposed at a first and a second end of the rod respectively. The rod further defines a first and a second expansion port connecting the first and the second expansion chambers respectively with the primary fluid chamber in fluid communication. As fluid within the primary fluid chamber expands from heating, the fluid may weep into the first and/or second expansion chambers through the first and/or second expansion ports respectively to maintain the integrity of a first and second cap bearing seal, which seal the fluid within the primary fluid chamber.

    摘要翻译： 阻尼器质量阻尼器组件包括杆和围绕杆环形地设置并且在它们之间限定主要流体室的壳体。 杆包括环形壁，其限定分别设置在杆的第一和第二端处的第一和第二膨胀室。 杆还限定了第一和第二膨胀口，其分别连接第一和第二膨胀室与主要流体室流体连通。 当主流体室内的流体从加热膨胀时，流体可以分别通过第一和/或第二膨胀端口进入第一和/或第二膨胀室，以保持第一和第二盖轴承密封的完整性， 主流体室内的流体。

    Ophthalmic fluid delivery system
    6.
    发明申请
    Ophthalmic fluid delivery system 审中-公开
    眼科输液系统

    公开(公告)号：US20090114742A1

    公开(公告)日：2009-05-07

    申请号：US12287150

    申请日：2008-10-06

    申请人： James F. Collins, JR.

    发明人： James F. Collins, JR.

    IPC分类号： A61M11/00

    CPC分类号： B05B17/0646 ,  A61F9/0008 ,  A61M11/005 ,  A61M11/041 ,  A61M11/042 ,  A61M11/065 ,  A61M2205/59 ,  A61M2210/0612 ,  B05B17/0623 ,  B05B17/0676

    摘要： An ophthalmic fluid delivery environment that includes a human eye in an open position and an atomizer having a nozzle aimed at the human eye in the open position, wherein a plume of ophthalmic fluid mist is directed by the nozzle so that the mist is received by the human eye in the open position and the received mist has a momentum that is insufficient to trigger to at least one of an ocular blink reflex and a lacrimation reflex of the human eye that receives the mist.

    摘要翻译： 一种眼科流体输送环境，其包括处于打开位置的人眼和在打开位置具有针对人眼的喷嘴的雾化器，其中，喷嘴引导一滴眼液雾，使得雾被 处于打开位置的人眼和接收的雾具有不足以触发接收雾的人眼的眼睛眨眼反射和流淌反射中的至少一种的动量。

    Caged nut with isolators
    8.
    发明授权
    Caged nut with isolators 失效
    笼式螺母与隔离器

    公开(公告)号：US4762451A

    公开(公告)日：1988-08-09

    申请号：US947196

    申请日：1986-12-29

    申请人： James F. Collins

    发明人： James F. Collins

    IPC分类号： B60R11/00 ,  F16B33/00 ,  F16B37/04 ,  F16B37/06 ,  F16B43/00

    CPC分类号： B60R11/00 ,  F16B33/004 ,  F16B37/044 ,  F16B37/062 ,  Y10S411/90

    摘要： Electrically non-conductive isolators are secured by a press fit into the apertures in the lugs of a metal, floating anchor type nut so as to electrically isolate the nut from an associate metal cage so that during the electro-deposition of paint onto the cage, the paint will not adhere to the nut or the internal threads of the nut.

    摘要翻译： 电气非导电隔离器通过压配合固定在金属浮动锚式螺母的凸耳中的孔中，以将螺母与相关金属保持架电隔离，使得在将涂料电沉积到保持架上时， 油漆不会粘在螺母或螺母的内螺纹上。