摘要:
A method for supplying rolling oil for cold rolling is provided wherein emulsion rolling oil is supplied using both: (i) a first rolling oil supply system for sypplying the emulsion rolling oil to a roll and a steel sheet being rolled in a recirculation mode, and (ii) a second rolling oil supply system for supplying the emulsion rolling oil to only the front and back surface of the stell sheet. The emulsion rolling oil supplied by the first and second supply systems comprise an emulsifier of a same type and concentration, and the second supply system is controlled so that an average particle diameter of emulsion is larger than an average particle diameter of emulsion of the first supply system. The emulsion of the second supply system, which has not stuck onto the steel sheet being rolled, is then joined to the emulsion of the first supply system.
摘要:
The invention relates to a pharmaceutical composition as a therapeutic agent for ischemic disease comprising a compound of the formula ##STR1## wherein R.sup.1 is carbamoyl substituted with morpholino (lower) alkyl, thiomorpholino(lower)alkyl or lower alkylamino(lower)alkyl; or ureido substituted with lower alkylamino(lower)alkyl; andR.sup.2 is phenyl substituted with nitro, andR.sup.4 is lower alkyl; orR.sup.2 is lower alkyl, andR.sup.4 is phenyl substituted with nitro;with proviso that R.sup.1 is carbamoyl substituted with thiomorpholino(lower)alkyl or lower alkylamino(lower)alkyl; or ureido substituted with lower alkylamino(lower)alkyl when R.sup.4 is lower alkyl; or its salt, as an active ingredient, in association with a pharmaceutically acceptable, substantially nontoxic carrier or excipient.
摘要:
The invention relates to compounds for treatment of hypertension, and cardiovascular and cerebrovascular diseases, which compounds are of the formula: ##STR1## wherein R.sup.1 is piperazinyl(lower)alkyl, carbamoyl substituted with piperazinyl(lower)alkyl, or piperazinylcarbonyl, in each of which a piperazinyl group may be substituted with lower alkyl, andR.sup.3 is hydrogen or halogen;R.sup.2 is phenyl substituted with nitro, andR.sup.4 is lower alkyl or halo(lower)alkyl; orR.sup.2 is lower alkyl, andR.sup.4 is phenyl substitured with nitro;and a pharmaceutically acceptable salt thereof.
摘要:
An electrical treatment method for soybean protein is performed in such a manner that a mixture of soybean protein and solvent is set in a first electrolytic tank having a cathode and solvent is set in a second electrolytic tank which is separated from above electrolytic tank by a diaphram or a salt bridge and is provided with an anode and DC voltage is given between the two electrodes for electrolytic treatment for soybean protein. The soybean protein's quality can be significantly improved.
摘要:
The invention relates to diphenylpyridazine compounds useful in the treatment of cerebrovascular disease, of the formula: ##STR1## wherein R.sup.1 is piperazinyl(lower)alkyl, carbamoyl substituted with piperazinyl(lower)alkyl, or piperazinylcarbonyl, in each of which a piperazinyl group may be substituted with lower alkyl,R.sup.2 is phenyl substituted with nitro, andR.sup.3 is hydrogen or halogen, or a pharmaceutically acceptable salt thereof.
摘要:
This invention relates to &bgr;-alanine derivatives represented by the following formula: wherein each symbol is as defined in the specification and pharmaceutically acceptable salt thereof which is glycoprotein IIb/IIIa antagonist, inhibitor of blood platelets aggregation and inhibitor of the binding of fibrinogen to blood platelets, to processes for the preparation thereof, to a pharmaceutical composition comprising the same and to a method for the prevention and/or treatment diseases indicated in the specification to a human being or an animal.
摘要:
The present invention concerns glycoprotein IIa/IIIb antagonists and platelet aggregation inhibitors of the formula (I): ##STR1## wherein R.sup.1 is aryl which may have one or more suitable substituent(s),R.sup.2 is carboxy(lower)alkyl or protected carboxy(lower)alkyl,R.sup.3 is carboxy or protected carboxy,A.sup.1 is alkylene which may have one or more suitable substituent(s),A.sup.2 is a group of the formula: ##STR2## (wherein R is lower alkyl), or a group of the formula:--NHCH.sub.2 CH.sub.2 CO--,A.sup.3 is lower alkylene which may have one or more suitable substituent(s),l, m and n are each the same or different an integer of 0 or 1,with proviso that A.sup.2 is not a group of the formula:--NHCH.sub.2 CH.sub.2 CO--,when l is an integer of 0.
摘要:
The invention relates to cardioprotective compounds of the formula: ##STR1## wherein R.sup.1, R.sup.2 R.sup.3 and R.sup.4 are moieties as described in the specification.
摘要:
An N-containing heterocyclic compound of the formula: ##STR1## wherein R.sup.1 is lower alkyl optionally substituted with hydroxy, halogen or a heterocyclic group, carboxy, esterified carboxy, carbamoyl optionally substituted with heterocyclic(lower)alkyl or lower alkylamino(lower)alkyl, N-containing heterocycliccarbonyl optionally substituted with lower alkyl, or ureido optionally substituted with lower alkylamino(lower)alkyl, andR.sup.3 is hydrogen or halogen;R.sup.2 is phenyl substituted with nitro, andX is .dbd.N--or ##STR2## in which R.sup.4 is lower alkyl or halo(lower)alkyl, or is taken together with R.sup.1 to form an N-containing heterocyclic group optionally substituted with oxo and lower alkylamino(lower)alkyl; orR.sup.2 is lower alkyl, andX is ##STR3## in which R.sup.4 is phenyl substituted with nitro; and a pharmaceutically acceptable salt thereof, processes for the preparation thereof and pharmaceutical (e.g. antihypertension) compositions comprising the same.