Method for treating a patient at risk of loss of cardiac function by cardiac ischemia
    5.
    发明授权
    Method for treating a patient at risk of loss of cardiac function by cardiac ischemia 有权
    用心脏缺血治疗心脏功能丧失危险的患者的方法

    公开(公告)号:US07392077B2

    公开(公告)日:2008-06-24

    申请号:US10822600

    申请日:2004-04-12

    Abstract: Various methods and devices for treating a patient who has lost, or is at risk of losing cardiac function by cardiac ischemia are disclosed. Treatment includes first imaging a patient's heart, or a portion thereof, to identify underperfused regions of cardiac muscle, and a source of oxygenated blood that is proximate to the underperfused region. Between the underperfused regions and the oxygenated blood source, a target area is selected where thermal or mechanical injury is introduced, and optionally reintroduced, to convert initial capillary blush, resulting from the injury.

    Abstract translation: 公开了用于治疗由于心脏缺血而失去或有丧失心脏功能风险的患者的各种方法和装置。 治疗包括首先对患者的心脏或其一部分进行成像以识别心肌的不足灌注区域,以及接近欠灌注区域的充氧血液源。 在欠灌注区域和氧合血液源之间,选择引入热或机械损伤的目标区域,并且可选地重新引入,以转化由损伤引起的初始毛细血管腮红。

    Method and devices for heart treatment
    6.
    发明授权
    Method and devices for heart treatment 有权
    心脏治疗方法和装置

    公开(公告)号:US06748258B1

    公开(公告)日:2004-06-08

    申请号:US09706584

    申请日:2000-11-03

    Abstract: Various methods and devices for treating a patient who has lost, or is at risk of losing cardiac function by cardiac ischemia are disclosed. Treatment includes first imaging a patient's heart, or a portion thereof, to identify underperfused regions of cardiac muscle, and a source of oxygenated blood that is proximate to the underperfused region. Between the underperfused regions and the oxygenated blood source, a target area is selected where thermal or mechanical injury is introduced, and optionally reintroduced, to convert initial capillary blush, resulting from the injury.

    Abstract translation: 公开了用于治疗由于心脏缺血而失去或有丧失心脏功能风险的患者的各种方法和装置。 治疗包括首先对患者的心脏或其一部分进行成像以识别心肌的不足灌注区域,以及接近欠灌注区域的充氧血液源。 在欠灌注区域和氧合血液源之间,选择引入热或机械损伤的目标区域,并且可选地重新引入,以转化由损伤引起的初始毛细血管腮红。

    Aneurysm closure device assembly
    7.
    发明授权
    Aneurysm closure device assembly 有权
    动脉瘤闭合装置组装

    公开(公告)号:US06344041B1

    公开(公告)日:2002-02-05

    申请号:US09699267

    申请日:2001-10-26

    Abstract: This is an artificial occlusion kit for implanting and retaining an artificial occlusion device in a body space adjacent to and extending from a body lumen in a mammal. The includes at least one occlusion device and a retaining device for blocking the migration of the occlusion device out of the occlusion site. The retaining device is radially expandable at a retaining site adjacent the body space to be occluded to a diameter that is sufficient to engage the body lumen wall at the retaining site and form a barrier across the entrance zone of the body space to be occluded. The expanded retaining device also forms a lumen for flow through body lumen at the retaining site. At least one semi-penetrable space may also be provided in the retaining device, allowing introduction of occlusion devices into the body space to be occluded, but preventing subsequent migration of the occlusion devices out of the body space. This semi-penetrable space may also be distensible to allow for delivery of occlusion devices therethrough. An introducer wire or a tapered-tip delivery catheter may be used to distend the distensible space and deliver the occlusion devices. The retaining device structure may further include a radiopaque metal wire wound into a primary helix over an inner core member made of a superelastic alloy of nickel and titanium. An implantable medical device assembly is also provided, having the structure described for the retaining device of the novel artificial occlusion kit, and which is attached to an elongate pusher via a sacrificial link that is electrolytically dissolvable.

    Abstract translation: 这是一种用于将人工闭塞装置植入和保持在与哺乳动物的体腔相邻并从其延伸的身体空间中的人造闭塞套件。 包括至少一个闭塞装置和用于阻挡闭塞装置移出闭塞部位的保持装置。 保持装置可以在靠近身体空间的保持位置处径向展开,以被阻塞到直径足以与保持位置处的身体腔壁接合并形成穿过要被遮挡的身体空间的入口区域的屏障。 扩张的保持装置还形成用于在保留位置处流过体腔的流明。 还可以在保持装置中设置至少一个半透入空间,从而允许将遮挡装置引入身体空间以被阻塞,但是防止闭塞装置随后从身体空间中移出。 这种半透入空间也可以是可扩张的,以允许通过其中的封闭装置的输送。 导引线或锥形输送导管可用于扩张可扩张空间并输送遮挡装置。 保持装置结构还可以包括在由镍和钛的超弹性合金制成的内芯构件上缠绕到主螺旋中的不透射线金属线。 还提供了一种植入式医疗装置组件,其具有针对新型人造阻塞套件的保持装置所述的结构,并且经由电解可溶解的牺牲连接件连接到细长推动器。

    Braided body balloon catheter
    8.
    发明授权
    Braided body balloon catheter 有权
    编织体气囊导管

    公开(公告)号:US06315757B1

    公开(公告)日:2001-11-13

    申请号:US09314568

    申请日:1999-05-19

    Abstract: This is a balloon catheter having braided layer which extends generally from the proximal end of the catheter to a location distal of the balloon. In particular, it is desirable that the shaft of the catheter proximal of the balloon be stiffest at the proximal section and least stiff just proximal of the balloon. Although the catheter may be a single lumen catheter using some type of a core wire to act as a valve for inflation and deflation of the balloon, it is within the scope of the invention to include either a separate inflation/deflation lumen or one incorporated into the various concentric polymeric layers used to make up the proximal shaft. Particularly preferred is the use of an elastic, compliant balloon.

    Abstract translation: 这是具有编织层的球囊导管,其通常从导管的近端延伸到气囊的远侧的位置。 特别地,期望球囊近端的导管的轴在近端部分处是最刚性的,并且最接近刚好在气囊附近。 尽管导管可以是使用某种类型的芯线作为气囊充气和放气的阀的单腔导管,但是在本发明的范围内还包括单独的充气/放气管腔或并入 用于构成近端轴的各种同心聚合物层。 特别优选的是使用弹性的柔顺气球。

    Super-elastic composite guidewire
    10.
    发明授权
    Super-elastic composite guidewire 失效
    超弹性复合导丝

    公开(公告)号:US5769796A

    公开(公告)日:1998-06-23

    申请号:US789607

    申请日:1997-01-22

    CPC classification number: A61M25/09 A61M2025/09091 A61M2025/09175

    Abstract: This is a composite guidewire for use in a catheter and is used for accessing a targeted site in a lumen system of a patient's body. The guidewire core or guidewire section may be of a stainless steel or a high elasticity metal alloy, preferably a Ni--Ti alloy, also preferably having specified physical parameters. The composite guidewire assembly is especially useful for accessing peripheral or soft tissue targets. Variations include multi-section guidewire assemblies having (at least) super-elastic distal portions and super-elastic braided reinforcements along the mid or distal sections. A variation of the inventive guidewire includes the coating of the wire with a tie layer and then with a one or more lubricious polymers to enhance its suitability for use within catheters and with the interior of vascular lumen.

    Abstract translation: 这是用于导管的复合导丝,并用于进入患者体内的管腔系统中的目标部位。 导丝芯或导丝部分可以是不锈钢或高弹性金属合金,优选Ni-Ti合金,也优选具有特定的物理参数。 复合导丝组件对于接近外周或软组织靶是特别有用的。 变型包括具有(至少)超弹性远端部分的多段导丝组件和沿着中部或远端部分的超弹性编织加强件。 本发明的导丝的变体包括用连接层涂覆线材,然后使用一种或多种润滑聚合物来增强其在导管内和血管腔内部使用的适用性。

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