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公开(公告)号:US09005605B2
公开(公告)日:2015-04-14
申请号:US13398779
申请日:2012-02-16
IPC分类号: A01N63/00 , A61K35/32 , A01N35/00 , A61K31/381 , A61K9/06 , A61K31/192 , A61K31/20 , A61K31/216 , A61K31/4015 , A61K31/4025 , A61K31/421 , A61K31/4412 , A61K31/728 , A61K47/36 , A61K8/46 , A61K8/49 , A61K8/70 , A61K8/73 , A61Q19/08 , A61K8/98 , A61L27/20 , A61L27/36 , A61L27/38 , A61L27/52 , A61L27/54 , A61L27/58
CPC分类号: A61K31/381 , A61K8/46 , A61K8/49 , A61K8/4913 , A61K8/70 , A61K8/73 , A61K8/981 , A61K9/06 , A61K31/192 , A61K31/20 , A61K31/216 , A61K31/4015 , A61K31/4025 , A61K31/421 , A61K31/4412 , A61K31/728 , A61K35/35 , A61K47/36 , A61K2800/91 , A61L27/20 , A61L27/3604 , A61L27/3645 , A61L27/3804 , A61L27/52 , A61L27/54 , A61L27/58 , A61L2300/412 , A61L2400/06 , A61L2430/04 , A61L2430/34 , A61Q19/08 , A61K2300/00 , C08L5/08
摘要: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
摘要翻译: 该说明书公开了用于治疗个体的软组织缺陷的组合物和方法。
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公开(公告)号:US08883139B2
公开(公告)日:2014-11-11
申请号:US13398783
申请日:2012-02-16
IPC分类号: A01N63/00 , A61F2/20 , A61K31/195 , A61K8/73 , A61K8/36 , A61K8/49 , A61L27/54 , A61K8/42 , A61K8/69 , A61L27/40 , A61K31/728 , A61K8/98 , A61K8/37 , A61K8/46 , A61L27/36 , A61Q19/08
CPC分类号: A61K31/195 , A61K8/361 , A61K8/37 , A61K8/42 , A61K8/46 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/4986 , A61K8/69 , A61K8/735 , A61K8/981 , A61K31/728 , A61K35/35 , A61K2800/91 , A61L27/3604 , A61L27/40 , A61L27/54 , A61L2300/412 , A61L2400/06 , A61L2430/04 , A61L2430/34 , A61Q19/08 , C08L5/08 , A61K2300/00
摘要: The invention relates to compositions comprising a hydrogel material that comprises a glycosaminoglycan polymer, adipose tissue and a compound of the structure The composition is administered to a site of a soft tissue condition including those of breast tissue. The hydrogel material can be porous or of solid particles. The glycosaminoglycan polymer can be a hyaluronan polymer.
摘要翻译: 本发明涉及包含水凝胶材料的组合物,其包含糖胺聚糖聚合物,脂肪组织和结构化合物。将组合物施用于包括乳房组织的软组织病症的部位。 水凝胶材料可以是多孔的或固体颗粒。 糖胺聚糖聚合物可以是透明质酸聚合物。
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公开(公告)号:US08741281B2
公开(公告)日:2014-06-03
申请号:US13398661
申请日:2012-02-16
申请人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
发明人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
CPC分类号: A61K31/381 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/4986 , A61K8/64 , A61K8/981 , A61K31/4015 , A61K31/4025 , A61K31/45 , A61K35/35 , A61K38/1767 , A61K45/06 , A61Q19/00 , A61K2300/00
摘要: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
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公开(公告)号:US20120219627A1
公开(公告)日:2012-08-30
申请号:US13398680
申请日:2012-02-16
申请人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
发明人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
CPC分类号: A61K31/4025 , A61K8/44 , A61K8/64 , A61K8/981 , A61K31/195 , A61K35/35 , A61K35/63 , A61K38/1767 , A61L27/40 , A61Q19/00 , A61K2300/00
摘要: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
摘要翻译: 本说明书公开了用于治疗个体的软组织缺陷的组合物和方法。
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公开(公告)号:US08900571B2
公开(公告)日:2014-12-02
申请号:US13398674
申请日:2012-02-16
申请人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
发明人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
IPC分类号: A01N63/00 , A61F2/20 , A61K8/49 , A61K8/64 , A61K31/5377 , A61K31/519 , A61K31/4025 , A61K8/98 , A61Q19/00 , A61K38/17 , A61K35/12
CPC分类号: A61K31/4025 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/4986 , A61K8/64 , A61K8/981 , A61K31/519 , A61K31/5377 , A61K35/35 , A61K38/1767 , A61Q19/00 , A61K2300/00
摘要: The invention relates to compositions comprising a silk fibroin material, adipose tissue and a compound of the structure where X1 and X5 are independently CH or N; X7 is NH, O or S; X8 and X9 are independently CH or N; R13 is an optionally substituted aryl or optionally substituted heteroaryl and R14 is C1-6 alkyl, optionally substituted aryl or optionally substituted heteroaryl. The composition is administered to a site of a soft tissue condition including those of breast tissue. The silk fibroin material can be in the form of a silk hydrogel, a silk film, a silk scaffold, a silk sheet, a silk porous material or a silk fiber. The silk fibroin material can be substantially sericin free.
摘要翻译: 本发明涉及包含丝素蛋白材料,脂肪组织和其中X1和X5独立地为CH或N的结构的化合物的组合物; X7是NH,O或S; X8和X9独立地为CH或N; R13是任选取代的芳基或任选取代的杂芳基,R 14是C 1-6烷基,任选取代的芳基或任选取代的杂芳基。 将组合物施用于包括乳房组织的组织状况的部位。 丝素蛋白材料可以是丝素水凝胶,丝膜,丝绸支架,丝绸片,丝多孔材料或丝纤维的形式。 丝素蛋白材料可以基本上不含丝胶蛋白。
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公开(公告)号:US20120269777A1
公开(公告)日:2012-10-25
申请号:US13398667
申请日:2012-02-16
申请人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
发明人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
CPC分类号: A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/4986 , A61K8/64 , A61K8/981 , A61K31/192 , A61K31/215 , A61K31/4015 , A61K31/4025 , A61K31/421 , A61K35/35 , A61K35/63 , A61K38/00 , A61K38/1767 , A61K2800/91 , A61Q19/08 , A61K2300/00
摘要: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
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公开(公告)号:US20120213853A1
公开(公告)日:2012-08-23
申请号:US13398674
申请日:2012-02-16
申请人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
发明人: Dennis E. Van Epps , Guang-Liang Jiang , Adam L. Collette , Rebecca L. Horan , Jingsong Chen , Gregory H. Altman , Wha Bin Im
IPC分类号: A61K9/00 , A61P1/00 , A61P13/00 , A61K35/12 , A61K8/49 , A61Q19/00 , A61P15/00 , A61P17/00 , A61P1/02
CPC分类号: A61K31/4025 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/4986 , A61K8/64 , A61K8/981 , A61K31/519 , A61K31/5377 , A61K35/35 , A61K38/1767 , A61Q19/00 , A61K2300/00
摘要: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
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公开(公告)号:US20120189589A1
公开(公告)日:2012-07-26
申请号:US13398777
申请日:2012-02-16
CPC分类号: C07D409/06 , A61K8/4913 , A61K8/4926 , A61K8/4986 , A61K8/73 , A61K8/981 , A61K9/06 , A61K31/381 , A61K31/4015 , A61K31/4025 , A61K31/4412 , A61K31/728 , A61K35/35 , A61K47/36 , A61K2800/91 , A61L27/20 , A61L27/3604 , A61L27/3645 , A61L27/3804 , A61L27/52 , A61L27/54 , A61L27/58 , A61L2300/412 , A61L2400/06 , A61L2430/04 , A61L2430/34 , A61Q19/08 , C07D207/46 , C07D333/60 , A61K2300/00 , C08L5/08
摘要: The specification discloses compositions and methods for treating a soft tissue defect of an individual.
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公开(公告)号:US20120045420A1
公开(公告)日:2012-02-23
申请号:US13193744
申请日:2011-07-29
IPC分类号: A61K35/12 , A61Q19/00 , A61Q19/08 , A61P17/00 , A61F2/12 , A61P27/02 , A61P15/00 , A61P1/00 , A61P13/00 , A61K8/98 , A61P43/00
CPC分类号: A61K35/35 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/4986 , A61K8/981 , A61K31/381 , A61K31/4015 , A61K31/4025 , A61K31/45 , A61K2800/91 , A61Q19/08 , A61K2300/00
摘要: The present specification discloses compositions and methods of transplanting tissue useful for treating a soft tissue condition of an individual.
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10.
公开(公告)号:US07893107B2
公开(公告)日:2011-02-22
申请号:US11291694
申请日:2005-11-30
申请人: Guang-Liang Jiang , Wha Bin Im , Larry A. Wheeler
发明人: Guang-Liang Jiang , Wha Bin Im , Larry A. Wheeler
IPC分类号: A61K31/19
CPC分类号: A61K31/00 , A61K9/5078 , A61K31/45 , A61K31/557 , A61K31/5575 , A61K31/558
摘要: Methods are provided directed to administering a therapeutically effective amount of a prostaglandin EP4 agonist component to a mammal afflicted with or prone to afflicted with a disease or condition selected from an esophageal ulcer, alcohol gastropathy, a duodenal ulcer, non-steroidal anti-inflammatory drug-induced gastropathy, non-steroidal anti-inflammatory drug-induced enteropathy and intestinal ischemia. Such administration results in treating the disease or condition.
摘要翻译: 提供的方法涉及将治疗有效量的前列腺素EP4激动剂组分施用于患有或易于患有选自食管溃疡,酒精胃食管炎,十二指肠溃疡,非甾体抗炎药物的疾病或病症的哺乳动物 诱发的胃病,非甾体抗炎药物引起的肠病和肠缺血。 这种给药导致治疗疾病或病症。
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