摘要:
This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of using and of making these compositions.
摘要:
Methods and compounds are disclosed for wound healing by modulating autophagy. A formulation for modulating autophagy comprises a first modulating compound (FAM) selected from compounds having the general structure (I):
wherein: L represents a linker selected from —C≡C—, (a tolan), —CH═CH— (a stilbene, preferably trans); or —CRa═CRb— a stilbene derivative; where Ra and Rb are independently H or phenyl optionally substituted with —(R3)p or —(R4)q; R1 to R4 are independent substituents at any available position of the phenyl rings, preferably at 3, 3′, 4, 4′, and/or 5, 5′; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be ≥1. Each R1 to R2 is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides. The formulation may also include an auxiliary autophagy modulating compound (AAM) as described herein. The formulation may include a hydrogel formed by the compounds themselves or otherwise and may include salts and/or complexes.
摘要:
This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of using and of making these compositions.
摘要:
This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of using and of making these compositions.
摘要:
The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three different molecular weights, and about 0.001-5% hyaluronic acid (HA) of molecular weight about 100 kDa or less, packaged in an aerosol spray container.
摘要:
The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three different molecular weights, and about 0.001-5% hyaluronic acid (HA) of molecular weight about 100 kDa or less, packaged in an aerosol spray container.
摘要:
An emulsion having stabilized perfluorocarbon(s) that includes an aqueous solution, an oil solution and a third phase which includes at least one perfluorocarbon and methods of making the stable perfluorocarbon containing emulsions. The aqueous and oil phases are first mixed together to form the emulsion. At least one perfluorocarbon is then added to the emulsion. Either the aqueous based solution or oil based solution may include at least one thickener. Moreover, the perfluorocarbon containing emulsion remains stable for a period of at least two weeks.
摘要:
A cosmetic composition, comprising the following components (A), (B), (C), and (D):(A) from 0.01 to 48% by mass of a fluorine-modified silicone having a polysiloxane unit represented by the following formulae (1) and (2): wherein, Rf represents a linear or branched perfluoroalkyl group having 6 carbon atoms; R1, R2, and R3 are the same or different and each represent a linear or branched hydrocarbon group having 1 to 6 carbon atoms; m represents a number of 2 to 6; n represents a number of 1 to 6; p represents a number of 3 to 50; s represents a number of 1 to 5; and a ratio between p and s satisfies 0.66≦p/(p+s)≦0.9, (B) from 0.01 to 40% by mass of a powder having been subjected to a surface treatment with tridecafluoro octyltriethoxysilane, (C) from 0.01 to 20% by mass of a fine zinc oxide particle having a specific surface area of 10 to 100 m2/g, with the proviso that the component (B) is excluded from the component (C), and (D) octyl para-methoxycinnamate, wherein, a mass ratio of the component (A) to the component (D), (A)/(D) is from 0.5 to 10.
摘要:
A packaged product includes a personal care medium, a propellant, and an aerosol container. The personal care medium and the propellant are stored with the aerosol container. At least one of the personal care medium and the propellant includes a non-flammable volatile agent that includes one or more organofluorine compounds. The one or more organofluorine compounds may include one or more trifluoropropene compounds, one or more tetrafluoropropene compounds, and/or one or more pentafluoropropane compounds.
摘要:
A pumpable liquid spray formulation for retarding degradation of color cosmetics, the pumpable liquid spray formulation comprising: water, 82.228% by weight; alcohol denat, 9.0% by weight; polyhydrostearic acid, 2.23% by weight; pvp, 2.0% by weight; methyl perfluorobutyl ether, 1.25% by weight; methyl perfluoroisobutyl ether, 1.25% by weight; dimethicone peg-7 phosphate, 0.75% by weight; ppg-3 benzyl ether myristate, 0.5% by weight; caprylyl glycol, 0.5% by weight; methyl methacrylate cross polymer, 0.12% by weight; sodium hydroxide, 0.07% by weight; sodium cocamidopropyl pg dimonium chloride phosphate, 0.05% by weight; glycereth-5 lactate, 0.01% by weight; N,2,3-trimethyl-2-isopropyl butamide, 0.01% by weight; ethylhexyl isononanoate, 0.01% by weight; isononyl isononanoate, 0.01% by weight; fragrance, 0.01% by weight; aloe barbandensis leaf extract, 0.001% by weight; and poloxamer 407, 0.001% by weight; wherein all of the foregoing percentage weights have a tolerance band of ±2% of their stated value.