公开(公告)号：US20060013813A1

公开(公告)日：2006-01-19

申请号：US11054281

申请日：2005-02-08

申请人： Peter Mezes ,  Luca Rastelli ,  John Herrmann ,  John MacDougall ,  Haihong Zhong ,  Stacie Casman ,  Frenc Boldog ,  Richard Shimkets ,  Linda Gorman ,  Andrew Eisen ,  Steven Spaderna ,  Corine Vernet ,  Constance Berghs ,  Kimberly Spytek ,  Vincent DiPippo ,  Bryan Zerhusen ,  John Peyman ,  Karen Ellerman ,  David Stone ,  William Grosse ,  John Alsobrook ,  Denise Lepley ,  Daniel Rieger ,  Catherine Burgess ,  Sholmit Edinger ,  Edward Voss ,  Charles Miller

发明人： Peter Mezes ,  Luca Rastelli ,  John Herrmann ,  John MacDougall ,  Haihong Zhong ,  Stacie Casman ,  Frenc Boldog ,  Richard Shimkets ,  Linda Gorman ,  Andrew Eisen ,  Steven Spaderna ,  Corine Vernet ,  Constance Berghs ,  Kimberly Spytek ,  Vincent DiPippo ,  Bryan Zerhusen ,  John Peyman ,  Karen Ellerman ,  David Stone ,  William Grosse ,  John Alsobrook ,  Denise Lepley ,  Daniel Rieger ,  Catherine Burgess ,  Sholmit Edinger ,  Edward Voss ,  Charles Miller

IPC分类号： C12Q1/68 ,  G01N33/53 ,  C07H21/04 ,  A61K39/395 ,  C07K14/705 ,  C07K16/18

CPC分类号： C12N9/2462 ,  A61K38/00 ,  A61K47/6829 ,  A61K47/6851 ,  A61K47/6869 ,  A61K2039/505 ,  C07K14/47 ,  C07K14/705 ,  C07K16/18 ,  G01N33/6893

摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.