摘要:
The present invention provides a compound of formula (I) or a prodrug thereof useful for treating or preventing irritable bowel syndrome, and a composition comprising the compound as an active ingredient. Also, the present invention provides a method for treating or preventing irritable bowel syndrome, which comprises administrating a therapeutically or prophylactically effective amount of the compound or the composition to a subject in need of treating or preventing irritable bowel syndrome.
摘要:
The present invention relates to a novel, high-yield and low-cost method for preparing entecavir, [1-S-(1α,3α,4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, an antiviral agent, and novel intermediates used therein.
摘要:
The present invention relates to a method for preparing Montelukast acid or its sodium salt by reacting a thiol compound with a Montelukast intermediate in the presence of a base in a medium comprising an ionic liquid compound. In accordance with the inventive method, highly pure Montelukast acid or its sodium salt, which is advantageously used as a raw material in the preparation of Montelukast, a leukotriene antagonist, can be easily prepared in a high yield.
摘要:
The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor (GIPF) polynucleotides and polypeptides. The invention further relates to the therapeutic use of GIPF to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
摘要:
Provided is a method and apparatus for reducing zapping delay, which may transmit base layer data for each burst in a time-slicing scheme, and output the base layer data of a channel to be changed at the time of changing the channel, thereby reducing the zapping delay.
摘要:
This invention relates to an outer garment, having a first and second front panels and a back panel wherein the front panels are integrally connected at their upper ends to the back panel; first and second front flaps horizontally extending respectively from the first and second front panels; first and second back flaps horizontally extending from both sides of the back panel; a front fastening means for fastening the first and second front panels together; a first fastening means for fastening the first front and back flaps together; and a second fastening means for fastening the second front and back flaps together. The panels and flaps are essentially coextensive and integrally constructed such that they form a two-dimensional panel. In addition, in the unfolded view of the outer garment, inner edges of the first and second front panels form an angle of about 70-90 degrees.
摘要:
Provided is a method and apparatus for reducing zapping delay, which may transmit base layer data for each burst in a time-slicing scheme, and output the base layer data of a channel to be changed at the time of changing the channel, thereby reducing the zapping delay.
摘要:
The present invention relates to a method for preparing montelukast, an inhibitor against leukotrienes, and an intermediate used therein. According to the inventive method, high-purity montelukast or its sodium salt can be prepared in a high yield.
摘要:
The present invention relates to a composition or a method for treating or preventing irritable bowel syndrome. The present invention uses Atractylodes japonica rhizome extract, preferably the ethanol water solution extract of Atractylodes japonica rhizome, more preferably the 35-65 v/v % ethanol water solution extract of Atractylodes japonica rhizome for treating or preventing irritable bowel syndrome. Atractylodes japonica rhizome extract shows a surprising effect in suppressing visceral hypersensitivity or improving defecation abnormality caused by stress or bowel irritability.