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公开(公告)号:US20220101171A1
公开(公告)日:2022-03-31
申请号:US16435435
申请日:2019-06-07
申请人: ELLEN TUANYING CHEN
发明人: ELLEN TUANYING CHEN
摘要: Self-powered scale-up toroidal array quantum processing memory device with controllable and adjustable state-switch valves (CASSV) of making and applications at room temperature in a One-Device-Assembly was invented. The devices comprise of multiple layer organo-metallic cross-linked polymers having various superlattice structures based on a double-pole electron-relay in an electron negative and an electron positive manner in the membranes that promoted Cooper pairs coherently transmitting waves within and cross the Josephson toroidal flexible junction barriers at zero-bias. In the One-Device-Assembly system, the CASSV valve provides a delicate balance and enables the whole device system working when an fJ energy consumption was in demand from the quantum qubits; or when an energy storage device stores 1.53 MJ/cm2 in demand for a routine automobile vehicle without energy dissipation.
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公开(公告)号:US08632925B2
公开(公告)日:2014-01-21
申请号:US13659974
申请日:2012-10-25
申请人: Ellen Tuanying Chen
发明人: Ellen Tuanying Chen
IPC分类号: H01M8/10
CPC分类号: H01M8/1004 , H01M4/9008 , H01M4/96 , H01M8/1011 , H01M2008/1095 , Y02E60/523
摘要: An electrolyte-free, oxygen-free, high power, and energy dense single fuel cell device is provided, along with methods for making and use. The fuel cell device is based on an electron-relay function using a nanostructured membrane prepared by cross-linking polymers, and having embedded within the membrane, a reactant. Use of the fuel cell device does not produce water, or CO2, and no oxygen is needed. The rechargeability of the fuel cell device revealed it can function as a portable battery.
摘要翻译: 提供了无电解质,无氧,高功率和能量致密的单燃料电池装置,以及制造和使用方法。 燃料电池装置基于使用通过交联聚合物制备的并且嵌入膜内的反应物制备的纳米结构膜的电子继电功能。 使用燃料电池装置不产生水或二氧化碳,不需要氧气。 燃料电池装置的可再充电性显示其可以用作便携式电池。
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公开(公告)号:US20190391106A1
公开(公告)日:2019-12-26
申请号:US15978102
申请日:2018-05-12
申请人: ELLEN TUANYING CHEN
发明人: ELLEN TUANYING CHEN
IPC分类号: G01N27/40 , G01N33/573 , G01N27/27 , G01N27/414 , G01N27/30
摘要: A dual-functioning electrochemical sensing device has invented for fast, direct ultrasensitive detection of protein, such as attomolar concentration (aM) Matrix Metalloproteinase (MMP) without a procedure of cycteine switch under label-free, probe-free and reagent-free conditions. The invented device comprises of an organic memcapacitive/memristive membrane by self-assembling forming polarized 3D array crossing-nanotube structures on a gold substrate that enables the membrane selectively induction of bio-communication with MMP-2 in the absence of interference from other proteins in human serum specimens, herein aM concentration MMP-2 can be reliably detected by two different methods.
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公开(公告)号:US20190137477A1
公开(公告)日:2019-05-09
申请号:US15984349
申请日:2018-05-19
申请人: ELLEN TUANYING CHEN
发明人: ELLEN TUANYING CHEN
IPC分类号: G01N33/487 , G01N27/416
摘要: The invented organic memristive and memcapacitive device comprises of arrayed cross-bar donut-shape toroidal matrix self-assembling membrane on an electrode mimicking mitochondria's double membrane and the direct electron-relay functions enables a bio-communication signal flow directly between endotoxin and the sensor at a single E. coli cell concentration under nature enzyme-free, antibody-free and reagent-free conditions. The sensor offers multiple functions for monitoring neuronal synapse pulse energy output under influence of Lipopolysaccharide (LPS) and other important biomarkers. The robust analytical performances of the device for monitoring endotoxins are important to human health.
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5.
公开(公告)号:US08641876B2
公开(公告)日:2014-02-04
申请号:US13373576
申请日:2011-11-21
申请人: Ellen Tuanying Chen
发明人: Ellen Tuanying Chen
IPC分类号: G01N27/327
CPC分类号: G01N33/57492 , G01N33/548 , G01N2610/00
摘要: The present invention provides a novel device for biosensing and energy storage. The present invented device comprises an electrode having a nanopore structured and bio-communicationally active cyclodextrin attached thereto. The device has demonstrated robust analytical performances for direct single subtype breast cancer measurements without mediators, or native enzyme, and without antibodies labeling; the device is capable to store energy by direct bio-communication with the living cancer cells at real time is demonstrated. It is beneficial in the health care diagnostic applications.
摘要翻译: 本发明提供一种用于生物传感和能量储存的新型装置。 本发明的装置包括具有附着于其上的纳米孔结构和生物通讯活性环糊精的电极。 该装置已经证明了无直接单次亚型乳腺癌测量的稳定的分析性能,无需介质或天然酶,无抗体标记; 该装置能够通过与生命癌细胞的直接生物通信来实时存储能量。 在医疗保健诊断应用中是有益的。
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公开(公告)号:US11531924B2
公开(公告)日:2022-12-20
申请号:US16435435
申请日:2019-06-07
申请人: Ellen Tuanying Chen
发明人: Ellen Tuanying Chen
摘要: The present invention provides a sensor and measuring method. The sensor comprises multiple-layer organo-metallic cross-linked polymers forming various superlattice nanostructured biomimetic membranes for sensing Cooper-pair wave transmissions causing intrinsic magnetic flux quantum observed based on a Josephson junction toroidal array and a controllable state-switch valve having a double-pole electron-relay that promoted Cooper pairs coherently transmitting waves in the membranes within and cross the Josephson toroidal junction barriers at zero-bias. The One-Device-Assembly system enables a femto-joule energy consumption for quantum qubits; or acting as an energy storage device that stores energy 1.53 MJ/cm2 for an application in automobile vehicles.
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公开(公告)号:US11041843B2
公开(公告)日:2021-06-22
申请号:US15984349
申请日:2018-05-19
申请人: Ellen Tuanying Chen
发明人: Ellen Tuanying Chen
IPC分类号: G01N33/00 , C12Q1/00 , G01N33/487 , G01N27/416
摘要: The invented organic memristor/memcapacitor device comprises arrayed cross-bar donut-shape toroidal matrix self-assembling membrane on an electrode mimicking mitochondria's double membrane surface structure and the direct electron-relay function, that used to mimic functions of Fibroblast Growth Factor Receptor 1 (FGFR1) and choline acetyltransferase (CHAT), which enables bio-communication signals flowing directly between the endotoxin interacted membrane electrode assembly (MEA) working electrode and a cathodic electrode; and from a biomarker Acetyl coenzyme A (AcCoA) interacted the MEA electrode and the cathodic electrode when applied a definite potential, respectively, for detection of a single E. coli cell and detection of a picomolar concentration of AcCoA under nature enzyme-free, antibody-free and reagent-free conditions. The sensor offers multiple functions for monitoring neuronal synapse pulse energy output. The robust analytical performances of the device for monitoring endotoxins in milk are important in the dairy industry.
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公开(公告)号:US20200018767A1
公开(公告)日:2020-01-16
申请号:US16512356
申请日:2019-07-15
申请人: ELLEN TUANYING CHEN
发明人: ELLEN TUANYING CHEN
IPC分类号: G01N33/68 , G01N27/27 , G01N27/416 , H01L27/28
摘要: A memristive/memcapacitive device with vertex double-helical polarized biomimetic protein nanotubules forming double membranes with potential gradient mimicking mitochondria's inner double membrane was invented. The memristive/memcapacitive device comprises a cross-linked conductive organic polymer having a single-wall cross-bar polarized nanotube self-assembling membrane (SAM) on a gold chip with a minimum 5 nm space between the nanotubes. Under an applied potential, a pair of vertex double-helical circular current flow induced the Fermi arcs states promoting a direct chelating with zinc ions of the Matrix Metalloproteinase (MMP-2), that made a dual-functioning direct ultrasensitive detection of protein in an attomolar concentration possible without a procedure of cycteine switch under label-free, probe-free and reagent-free conditions. The energy harvesting feature is also disclosed.
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公开(公告)号:US11708595B2
公开(公告)日:2023-07-25
申请号:US16742745
申请日:2020-01-14
申请人: Ellen Tuanying Chen
发明人: Ellen Tuanying Chen
IPC分类号: G06N10/40 , C12Q1/00 , G01N27/414 , G01N33/543 , G01N27/327 , H10N60/12 , H10N60/00 , H10N60/80 , H10N60/85 , H10N69/00 , B82Y5/00
CPC分类号: C12Q1/002 , G01N27/3278 , G01N27/4145 , G01N27/4146 , G01N33/5438 , H10N60/12 , H10N60/805 , H10N60/851 , H10N60/99 , H10N69/00 , B82Y5/00
摘要: A multiple functioning superconductive device was invented based on Toroidal Josephson Junction (FFTJJ) array with 3D-cage structure self-assembled organo-metallic superlattice membrane. The device not only mimics the structure and function of an activated Matrix Metalloproteinase-2 (MMP-2) protein, but also mimics the cylinder structure of the Heat Shock Protein (HSP60) protein, that works at room temperature under a normal atmosphere, and without external electromagnetic power applied. The device enabled direct rapid real-time monitoring atto-molarity concentration ATP in biological specimens and was able to define the anti-inflammatory and pro-inflammatory status revealed a transitional range of ATP concentration under antibody-free, tracer-free and label-free conditions.
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公开(公告)号:US11079354B2
公开(公告)日:2021-08-03
申请号:US16865340
申请日:2020-05-02
申请人: Ellen Tuanying Chen
发明人: Ellen Tuanying Chen
IPC分类号: G01N27/416 , G01N27/27 , G01N33/487 , H01L51/00 , C12Q1/00 , H01L27/28
摘要: Multiple Josephson toroidal vertex quantum superconductive/memristive and superconductive/memcapacitive devices were invented with various superlattice structures, which work at room temperature without an applied external magnetic flux. The first type of the superlattices of the devices comprises of multiple-layers of organometallic polymers on gold chips by self-assembling that mimics the function of Matrix Metalloproteinase-2 (MMP-2). Another type of quantum superconductor/memristor comprises of multiple-organic polymers cross-linked with MMP-2 protein forming Josephson toroidal vertex on the gold surface. Models of the quantum superconductive/memristive and superconductive/memcapacitive devices were fabricated in nano superlattice structures and the devices module configurations were described. Three different methods were used to evaluate the devices' applications in sub fg/mL collagen-1 sensing, energy storage, and the super-position characteristics as a potential quantum bit device. The superconductivity, memristive, and memcapacitive functions were also evaluated in multiple methods, respectively.
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