-
公开(公告)号：US20110244513A1
公开(公告)日：2011-10-06
申请号：US12691868
申请日：2010-01-22
申请人： JENNY VALLADEAU , ODILE RAVEL , ELIZABETH ESTHER MARY BATES , JOHN FORD , SEM SAELAND , SERGE J.E. LEBECQUE
发明人： JENNY VALLADEAU , ODILE RAVEL , ELIZABETH ESTHER MARY BATES , JOHN FORD , SEM SAELAND , SERGE J.E. LEBECQUE
CPC分类号： C07K14/705 , C07K14/7056 , C07K16/28 , C07K2317/77
摘要： Nucleic acids encoding various lymphocyte cell proteins from mammalian, including primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
摘要翻译： 描述了编码来自哺乳动物的各种淋巴细胞蛋白的核酸，包括与其相关的灵长类动物，包括特异性抗体的试剂和纯化的蛋白质。 还提供了使用所述试剂和相关诊断试剂盒的方法。
-
2.发明授权Use of chimeric receptors in a screening assay for identifying agonists and antagonists of cell receptors 失效在筛选测定中使用嵌合受体鉴定细胞受体的激动剂和拮抗剂公开(公告)号：US07700728B2
公开(公告)日：2010-04-20
申请号：US11388884
申请日：2006-03-24
CPC分类号： G01N33/5008 , C07K14/705 , C07K14/70503 , C12N15/62 , G01N33/502 , G01N33/5044 , G01N33/566 , G01N2333/705
摘要： The present invention provides novel materials and screening methods for identifying agonists and antagonists of cell receptors. Methods are disclosed for identifying agonists and antagonists using chimeric receptors comprising the extracellular ligand-binding domain of a first receptor fused with the transmembrane and intracellular domains of a second receptor containing an intracellular immunoreceptor tyrosine-based activation motif (ITAM).
摘要翻译： 本发明提供用于鉴定细胞受体的激动剂和拮抗剂的新型材料和筛选方法。 公开了用于鉴定激动剂和拮抗剂的方法，所述嵌合受体包含与含有细胞内免疫受体酪氨酸的活化基序（ITAM）的第二受体的跨膜和胞内结构域融合的第一受体的细胞外配体结合结构域。
-
公开(公告)号：US06361939B1
公开(公告)日：2002-03-26
申请号：US08978289
申请日：1997-11-25
申请人： Elizabeth Esther Mary Bates , Blandine Marie de Saint-Vis , Christophe Caux , Serge J. E. Lebecque , Jacques Banchereau
发明人： Elizabeth Esther Mary Bates , Blandine Marie de Saint-Vis , Christophe Caux , Serge J. E. Lebecque , Jacques Banchereau
IPC分类号： C07H2104
CPC分类号： C07K14/70503 , C07K2319/00 , Y10S435/975
摘要： Polynucleotides encoding various dendritic cell specific proteins from a primate are provided. Uses of purified sequences are also disclosed, including producing related reagents, e.g., specific antibodies, and purified proteins. Methods of using these reagents and related diagnostic kits are also described.
摘要翻译： 提供了从灵长类动物编码各种树突状细胞特异性蛋白质的多核苷酸。 还公开了纯化序列的用途，包括产生相关试剂，例如特异性抗体和纯化的蛋白质。 还描述了使用这些试剂和相关诊断试剂盒的方法。
-
公开(公告)号：US06277959B1
公开(公告)日：2001-08-21
申请号：US09111470
申请日：1998-07-08
申请人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
发明人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
IPC分类号： A61K3900
CPC分类号： C07K14/705 , C07K14/7056 , C07K16/28 , C07K2317/77
摘要： Nucleic acids encoding various lymphocyte cell proteins from mammalian, including primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
摘要翻译： 描述了编码来自哺乳动物的各种淋巴细胞蛋白的核酸，包括与其相关的灵长类动物，包括特异性抗体的试剂和纯化的蛋白质。 还提供了使用所述试剂和相关诊断试剂盒的方法。
-
公开(公告)号：US07691373B2
公开(公告)日：2010-04-06
申请号：US11620440
申请日：2007-01-05
申请人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
发明人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
IPC分类号： A61K39/395 , A61K39/00 , A61K39/38
CPC分类号： C07K14/705 , C07K14/7056 , C07K16/28 , C07K2317/77
摘要： Nucleic acids encoding various lymphocyte cell proteins from mammalian, including primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
摘要翻译： 描述了编码来自哺乳动物的各种淋巴细胞蛋白的核酸，包括与其相关的灵长类动物，包括特异性抗体的试剂和纯化的蛋白质。 还提供了使用所述试剂和相关诊断试剂盒的方法。
-
公开(公告)号：US07179467B2
公开(公告)日：2007-02-20
申请号：US11230749
申请日：2005-09-20
申请人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
发明人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
CPC分类号： C07K14/705 , C07K14/7056 , C07K16/28 , C07K2317/77
摘要： Nucleic acids encoding various lymphocyte cell proteins from mammalian, including primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
摘要翻译： 描述了编码来自哺乳动物的各种淋巴细胞蛋白的核酸，包括与其相关的灵长类动物，包括特异性抗体的试剂和纯化的蛋白质。 还提供了使用所述试剂和相关诊断试剂盒的方法。
-
公开(公告)号：US07034137B2
公开(公告)日：2006-04-25
申请号：US10829107
申请日：2004-04-21
申请人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
发明人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
CPC分类号： C07K14/705 , C07K14/7056 , C07K16/28 , C07K2317/77
摘要： Nucleic acids encoding various lymphocyte cell proteins from mammalian, including primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
-
公开(公告)号：US06756478B2
公开(公告)日：2004-06-29
申请号：US09862802
申请日：2001-05-22
申请人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
发明人： Jenny Valladeau , Odile Ravel , Elizabeth Esther Mary Bates , John Ford , Sem Saeland , Serge J. E. Lebecque
IPC分类号： C07K100
CPC分类号： C07K14/705 , C07K14/7056 , C07K16/28 , C07K2317/77
摘要： Nucleic acids encoding various lymphocyte cell proteins from mammalian, including primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
摘要翻译： 描述了编码来自哺乳动物的各种淋巴细胞蛋白的核酸，包括与其相关的灵长类动物，包括特异性抗体的试剂和纯化的蛋白质。 还提供了使用所述试剂和相关诊断试剂盒的方法。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.024 秒)
