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    Filter plate shifter
    3.
    发明授权
    Filter plate shifter 有权
    滤板移位器

    公开(公告)号：US08999160B1

    公开(公告)日：2015-04-07

    申请号：US13633099

    申请日：2012-10-01

    Applicant: Daniel Simpson

    Inventor： Ferdinand Kogler

    IPC: B01D25/172 ,  B01D25/21 ,  B01D25/12

    CPC classification number: B01D25/125 ,  B01D25/164 ,  B01D25/172

    Abstract: A mechanical plate shifter system for moving filter plates in a filter press during a process of plate separation for filter cake removal comprises: a pusher to automatically engage with a single filter plate at the end of a stack or at the edge of a gap in the stack for moving the plate forward and then automatically disengaging when the plate reaches an end plate/dummy plate or another filter plate previously pushed. The filter plates are configured with handles for engaging with the pusher. The pusher is attached to a continuous drive belt and is configured with a pivoting structure including: a head with a receiving notch for a handle of a filter plate; and a counterweight for the head. The pusher and belt are configured relative to the filter plate stack to allow for filter plates to be engaged/disengaged by the receiving notch.

    Abstract translation: 在用于滤饼去除的板分离过程中用于在压滤机中移动过滤板的机械板移动器系统包括：推动器，用于在堆叠的端部处或在堆叠中的间隙的边缘处与单个过滤板自动接合 当板到达端板/虚拟板或先前推动的另一个过滤板时，将板向前移动然后自动脱开。 过滤板配置有用于与推动器接合的把手。 推动器附接到连续的传动带并且构造为具有枢转结构，其包括：具有用于过滤板的手柄的接收凹口的头部; 和一个配重的头。 推动器和带相对于过滤板堆叠构造以允许过滤板通过接收凹口接合/分离。

    CLEAVABLE SURFACTANTS
    4.
    发明申请
    CLEAVABLE SURFACTANTS 有权
    可清洁的表面活性剂

    公开(公告)号：US20090095628A1

    公开(公告)日：2009-04-16

    申请号：US12249584

    申请日：2008-10-10

    Applicant: Sergei Saveliev ,  Daniel Simpson ,  Keith V. Wood

    Inventor： Sergei Saveliev ,  Daniel Simpson ,  Keith V. Wood

    IPC: C07K1/26 ,  C07C309/64 ,  C07D307/02 ,  C07D317/10 ,  C07K1/14 ,  C12N9/96 ,  C12Q1/37 ,  C07K1/16

    CPC classification number: C11D1/20 ,  C07C309/10 ,  C07C309/14 ,  C07C309/15 ,  C07C309/16 ,  C07C323/12 ,  C07C329/06 ,  C07D307/40 ,  C07D307/56 ,  C07D317/22 ,  C07D333/16 ,  C11D1/143

    Abstract: The invention provides surfactant compounds of formulas I-IX, which can be used in methods for aiding the solubilization, digestion, preparation, analysis, and/or characterization of biological material, for example, proteins or cell membranes. The compounds can also aid in the recovery of peptides generated during protein digestion, particularly for in-gel digestion protocol. Additionally, the compounds can improve enzymatic protein deglycosylation without interfering with downstream sample preparation steps and mass spectrometric analysis. The compounds can be specifically useful as digestion aids that can be decomposed by an acid, by heat, or a combination thereof. Decomposition of the surfactants allows for facile separation from isolated samples, and/or allows for analysis of the sample without interfering with the sensitivity of various analytical techniques.

    Abstract translation: 本发明提供式I-IX的表面活性剂化合物，其可用于帮助生物材料例如蛋白质或细胞膜的增溶，消化，制备，分析和/或表征的方法。 这些化合物还可以帮助回收在蛋白质消化过程中产生的肽，特别是对于凝胶内消化方案。 另外，这些化合物可以改善酶蛋白去糖基化而不干扰下游样品制备步骤和质谱分析。 这些化合物可以特别用作能够被酸，加热或其组合分解的消化助剂。 表面活性剂的分解允许从分离的样品中容易地分离，和/或允许分析样品而不干扰各种分析技术的灵敏度。

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