公开(公告)号：US11036354B2

公开(公告)日：2021-06-15

申请号：US15383909

申请日：2016-12-19

申请人： Daniel Schwartz ,  Arin Bhowmick

发明人： Daniel Schwartz ,  Arin Bhowmick

IPC分类号： G06F3/048 ,  G06F3/0482 ,  H04L29/08

摘要： A system and method for facilitating user interface interactions between different computing devices. An example method includes providing a first user option to select a first portion of a first user interface display screen presented on a first computing device; providing a signal based on the selected portion; and using the signal to display one or more items in a second user interface display screen via a second computing device based on the first portion and one or more mapping rules. In a more specific embodiment, the example method further includes providing a second user option to adjust the mapping rules. The first portion includes, for example, a table row or column. The one or more items displayed via the second computing device include, for example, a visualization based on data associated with the first portion.

公开(公告)号：US20130074063A1

公开(公告)日：2013-03-21

申请号：US13234382

申请日：2011-09-16

申请人： Daniel Schwartz ,  Arin Bhowmick ,  Harris Kravatz ,  Michael Remington

发明人： Daniel Schwartz ,  Arin Bhowmick ,  Harris Kravatz ,  Michael Remington

IPC分类号： G06F9/445

CPC分类号： G06F8/10 ,  G06F8/61 ,  G06Q10/0631 ,  G06Q10/06311

摘要： Various arrangements for installing, setting up, and configuring enterprise software are presented. A set of business characteristics may be received in response to a questionnaire. The set of business characteristics may be analyzed in conjunction with various tasks of one task lists, wherein each task comprises one or more data gathering setup steps for enterprise software. Using the business characteristics, various tasks may be identified as requiring or not requiring user input because of the applicability to the customer. A task list that indicates tasks needing to be completed may be presented to the user.

摘要翻译： 介绍了安装，设置和配置企业软件的各种安排。 响应问卷可以收到一组业务特征。 可以结合一个任务列表的各种任务分析一组业务特征，其中每个任务包括用于企业软件的一个或多个数据收集设置步骤。 使用业务特征，可以将各种任务识别为由于对客户的适用性而要求或不要求用户输入。 指示需要完成的任务的任务列表可以被呈现给用户。

公开(公告)号：US20120150847A1

公开(公告)日：2012-06-14

申请号：US12964346

申请日：2010-12-09

申请人： FILIP RADLINSKI ,  NICK CRASWELL ,  PETER BAILEY ,  DANIEL SCHWARTZ ,  AIDAN CROOK ,  LIKHITA KRISHNAMURTHY

发明人： FILIP RADLINSKI ,  NICK CRASWELL ,  PETER BAILEY ,  DANIEL SCHWARTZ ,  AIDAN CROOK ,  LIKHITA KRISHNAMURTHY

IPC分类号： G06F17/30

CPC分类号： G06F17/30867

摘要： Methods and computer-readable media are provided for improving the efficiency of the interleaving process. Once it is determined that a search query is to be used in an interleaving experiment, a primary ranking system and a secondary ranking system are analyzed to determine whether their respective search results for that search query would be identical. If the search results would be identical, the search query is routed only to the primary ranking system and not the secondary ranking system. If, however, it is determined that the search results would not be identical, both the primary ranking system and the secondary ranking system receive the search query for processing.

摘要翻译： 提供了用于提高交错处理效率的方法和计算机可读介质。 一旦确定在交织实验中使用搜索查询，则分析主要排名系统和次级排名系统以确定其针对该搜索查询的各自的搜索结果是否相同。 如果搜索结果相同，则搜索查询仅被路由到主要排名系统而不是辅助排名系统。 然而，如果确定搜索结果不相同，则主要排名系统和次级排名系统都接收用于处理的搜索查询。

公开(公告)号：US07995814B2

公开(公告)日：2011-08-09

申请号：US11767187

申请日：2007-06-22

申请人： Jeffrey P. Fingler ,  Scott E. Fraser ,  Daniel Schwartz

发明人： Jeffrey P. Fingler ,  Scott E. Fraser ,  Daniel Schwartz

IPC分类号： G06K9/00 ,  A61B6/00

CPC分类号： A61B5/0261 ,  A61B3/102 ,  A61B5/0066 ,  G01N21/4795 ,  G01N2021/1787

摘要： The methods described herein are methods to ascertain motion contrast within optical coherence tomography data based upon phase variance. The phase variance contrast observes the nanometer scale motion of scatterers associated with Brownian motion and other non-flow motion. The inventive method of calculating motion contrast from the phase variance can differentiate regions of different mobility based on the motion contrast differences, and can use the phase information to characterize mobility properties of the scatterers. In flow regions, the inventive method for acquiring and analyzing motion contrast can identify the regions as well as characterize the motion. Furthermore, the inventive method can determine quantitative flow estimation, the index of refraction variations, and absorption variations within flow regions.

摘要翻译： 本文描述的方法是基于相位方差来确定光学相干断层摄影数据内的运动对比度的方法。 相位差对比度观察与布朗运动和其他非流动运动相关的散射体的纳米级运动。 从相位方差计算运动对比度的本发明方法可以基于运动对比差异来区分不同移动性的区域，并且可以使用相位信息来表征散射体的移动性质。 在流动区域中，用于获取和分析运动对比度的本发明的方法可以识别区域以及表征运动。 此外，本发明的方法可以确定流量区域中的定量流量估计，折射率变化指数和吸收变化。

公开(公告)号：US20070260311A1

公开(公告)日：2007-11-08

申请号：US11743119

申请日：2007-05-01

申请人： Jagdish Jethmalani ,  Daniel Schwartz ,  Julia Kornfield ,  Robert Grubbs ,  Christian Sandstedt

发明人： Jagdish Jethmalani ,  Daniel Schwartz ,  Julia Kornfield ,  Robert Grubbs ,  Christian Sandstedt

IPC分类号： A61F2/16 ,  G02B1/00 ,  G02C7/04

CPC分类号： G02B3/00 ,  A61F2/1627 ,  A61F2/1635 ,  A61L27/18 ,  A61L2430/16 ,  G02B1/043 ,  G02C7/04 ,  G02C2202/14 ,  C08L83/04

摘要： The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. When at least a portion of the lens is exposed to an appropriate stimulus, the refraction modulating composition forms a second polymer matrix. The amount and location of the second polymer matrix may modify a lens characteristic such as lens power by changing its refractive index and/or by altering its shape. The inventive lenses have a number of applications in the electronics and medical fields as data storage means and as medical lenses, particularly intraocular lenses, respectively.

摘要翻译： 本发明涉及能够进行后制造功率修改的透镜。 通常，本发明的镜片包括（i）第一聚合物基质和（ii）能够刺激诱导的聚合分散在其中的折射调节组合物。 当透镜的至少一部分暴露于适当的刺激时，折射调节组合物形成第二聚合物基质。 第二聚合物基质的量和位置可以通过改变其折射率和/或通过改变其形状来改变诸如透镜功率的透镜特性。 本发明的镜片在电子和医疗领域中有许多应用，分别作为数据存储装置和医疗镜片，特别是眼内透镜。

公开(公告)号：US20070131873A1

公开(公告)日：2007-06-14

申请号：US11304305

申请日：2005-12-14

申请人： Daniel Allred ,  Daniel Schwartz

发明人： Daniel Allred ,  Daniel Schwartz

IPC分类号： H01J37/20

CPC分类号： H01J37/20 ,  H01J2237/26 ,  H01J2237/262 ,  Y10T428/24331

摘要： Unsupported, electron transparent film useful in supporting a sample for imaging and analysis by transmission electron microscopy; methods for making and using the unsupported, electron transparent film; and an integrally formed combination of an unsupported, electron transparent film and substrate.

摘要翻译： 不支持的电子透明膜，用于支持通过透射电子显微镜进行成像和分析的样品; 制造和使用无支撑的电子透明膜的方法; 以及未负载的电子透明膜和基板的整体形成的组合。

公开(公告)号：US20070129802A1

公开(公告)日：2007-06-07

申请号：US11598168

申请日：2006-11-10

申请人： Jagdish Jethmalani ,  Shiao Chang ,  Robert Grubbs ,  Julia Kornfield ,  Daniel Schwartz ,  Christian Sandstedt ,  F. Christ

发明人： Jagdish Jethmalani ,  Shiao Chang ,  Robert Grubbs ,  Julia Kornfield ,  Daniel Schwartz ,  Christian Sandstedt ,  F. Christ

IPC分类号： A61F2/16 ,  B29D11/00 ,  A61F9/013

CPC分类号： A61F2/16 ,  A61F2/1613 ,  A61F2/1616 ,  A61F2/1627 ,  A61F2/1635 ,  A61F2002/1699 ,  A61L27/14 ,  A61L27/50 ,  A61L2430/16 ,  B29D11/00009 ,  B29D11/00355 ,  B29D11/023 ,  G02C7/02 ,  G02C2202/14

摘要： The present invention relates to a method for creating shaped implants, such as intraocular lenses in vivo, as well as the novel implants themselves. Utilizing the method of the invention, it is possible to create an implant in vivo and to adjust either the physical properties such as refractive index, viscosity, etc., mechanical properties such as modulus, tensile strength, tear, etc., or the shape of the implant by noninvasive means. For example, using the method of the patent it is possible to create an intraocular lens in vivo and then adjust the shape and power of the lens through no invasion means. The novel implants are also addressed in this application.

摘要翻译： 本发明涉及一种用于产生成形植入物的方法，例如体内的眼内透镜，以及新颖的植入物本身。 利用本发明的方法，可以在体内产生植入物，并且可以调节诸如折射率，粘度等的物理性质，模量，拉伸强度，撕裂等的机械性能或形状 的植入物通过无创手段。 例如，使用该专利的方法，可以在体内产生眼内透镜，然后通过无侵入手段来调整透镜的形状和功率。 本申请中还提到了新颖的植入物。

公开(公告)号：US20070019502A1

公开(公告)日：2007-01-25

申请号：US11391981

申请日：2006-03-28

申请人： Timothy Foley ,  P. Beaty ,  Michael Walters ,  Alexander Clark ,  Dwight Livingston ,  A. Lentz ,  Miroslaw Bartkowiak ,  Daniel Schwartz ,  Nicholas Bachur

发明人： Timothy Foley ,  P. Beaty ,  Michael Walters ,  Alexander Clark ,  Dwight Livingston ,  A. Lentz ,  Miroslaw Bartkowiak ,  Daniel Schwartz ,  Nicholas Bachur

IPC分类号： B01F13/08

CPC分类号： B01F9/0016 ,  B01F13/0818 ,  B01F2009/0063 ,  G01N35/00 ,  G01N35/028 ,  G01N2035/00465

摘要： A system comprising one or more sample vessels is provided, the sample vessels comprising a liquid growth medium and a stirrer element, the stirrer element capable of being influenced by a magnetic force, and an incubation and measurement module comprising one or more openings for holding the one or more sample vessels. The incubation and measurement module further comprises at least two drive magnets associated with each of the sample vessels, and a magnet driver adapted to repeatedly move each of the at least two drive magnets toward and away from the surface of the associated sample vessel.

摘要翻译： 提供了包括一个或多个样品容器的系统，所述样品容器包括液体生长培养基和搅拌器元件，所述搅拌器元件能够受到磁力的影响，以及培养和测量模块，包括一个或多个开口，用于保持 一个或多个样品容器。 孵化和测量模块还包括与每个样品容器相关联的至少两个驱动磁体，以及磁体驱动器，其适于将至少两个驱动磁体中的每一个朝向和远离相关联的样品容器的表面移动。

公开(公告)号：US20060259250A1

公开(公告)日：2006-11-16

申请号：US11130310

申请日：2005-05-16

申请人： Daniel Schwartz

发明人： Daniel Schwartz

IPC分类号： G06F19/00

CPC分类号： G16B40/00 ,  G16B30/00

摘要： A method for extraction of statistically significant motifs from large naturally occurring datasets relies upon the intrinsic alignment of the data, extracting motifs through iterative comparison to a dynamic statistical background. In the preferred embodiment, a series of statistical correlations is performed to determine the most significant correlated residues, which in turn are used to identify a motif. The motif is then removed from the dataset and the routine is repeated until no more motifs are found. The motifs are identified in the context of a core residue with respect to a user-selected background, building significant motifs from smaller motifs. In the initial step, the sequence data is justified around a selected core residue. A second matrix that contains a background dataset is then created. The binomial probability of each residue in every column of the data matrix is calculated and the residue-column pair which had the lowest binomial probability below a defined threshold is selected. Those sequences in the background and data matrices that contain that significant residue at the appropriate column are extracted and placed into new matrices. The process is repeated for successive ones of these new matrices until no residue-column pairs with p-values below the threshold are detected. Upon completion, a motif is identified by listing each of the residue-column pairs that have been found to be statistically significant. Next, all sequences from matrices the background and data matrices that contain that motif are removed from those matrices and the process is repeated using the same core residue, completing when no significant residue-column pairs are detected.

摘要翻译： 从大型天然存在的数据集中提取统计学上显着的基序的方法取决于数据的内在对齐，通过迭代比较提取图案到动态统计背景。 在优选实施例中，执行一系列统计相关性以确定最显着的相关残基，其又用于识别基序。 然后从数据集中删除图案，并重复该程序，直到找不到更多的图案。 相对于用户选择的背景，在核心残基的上下文中鉴定基序，从较小图案构建显着的基序。 在初始步骤中，序列数据围绕选定的核心残基进行校正。 然后创建包含背景数据集的第二个矩阵。 计算数据矩阵每列中每个残差的二项概率，并选择具有低于定义阈值的二项概率最低的残差列对。 在背景中的那些序列和包含在适当列处的显着残基的数据矩阵被提取并置于新的基质中。 对这些新矩阵中的连续的这些新矩阵重复该过程，直到没有检测到p值低于阈值的残留列对。 完成后，通过列出已被发现具有统计学意义的每个残基 - 列对来鉴定基序。 接下来，从这些矩阵中除去包含该基序的背景和数据矩阵的矩阵的所有序列，并且使用相同的核心残基重复该过程，当没有检测到显着的残基 - 列对时完成。

公开(公告)号：US20050282750A1

公开(公告)日：2005-12-22

申请号：US11055309

申请日：2005-02-10

申请人： Daniel Schwartz ,  Keith Duncan ,  Kathy Bailey ,  John Kane ,  Brian Ishida

发明人： Daniel Schwartz ,  Keith Duncan ,  Kathy Bailey ,  John Kane ,  Brian Ishida

IPC分类号： A61K31/56 ,  A61K31/66 ,  A61K38/17

CPC分类号： A61K31/685 ,  A61K31/66 ,  A61K38/17 ,  A61K38/1709 ,  A61K2300/00

摘要： The present invention addresses the treatment of age-related macular degeneration using regulation of pathogenic mechanisms similar to atherosclerosis. In further specific embodiments, compositions that increase reverse cholesterol transport are utilized as therapeutic targets for age-related macular degeneration. In a specific embodiment, the lipid content of the retinal pigment epithelium, and/or Bruch's membrane is reduced by delivering Apolipoprotein A1, particularly a mimetic peptide.

摘要翻译： 本发明通过调节与动脉粥样硬化相似的致病机制来解决年龄相关性黄斑变性的治疗。 在另外的具体实施方案中，增加反向胆固醇转运的组合物被用作年龄相关性黄斑变性的治疗靶标。 在一个具体的实施方案中，通过递送载脂蛋白A1，特别是模拟肽来减少视网膜色素上皮和/或Bruch's膜的脂质含量。