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    Method of fabricating a thermoplastic rubber encapsulated transformer
    4.
    发明授权
    Method of fabricating a thermoplastic rubber encapsulated transformer 失效
    制造热塑性橡胶密封变压器的方法

    公开(公告)号：US06682681B1

    公开(公告)日：2004-01-27

    申请号：US08476050

    申请日：1995-06-07

    申请人： William A. Clark ,  Carl Craig Strickland, Jr. ,  Mark Christopher Newman

    发明人： William A. Clark ,  Carl Craig Strickland, Jr. ,  Mark Christopher Newman

    IPC分类号： B29C4514

    CPC分类号： H01F41/005 ,  B29C45/14639 ,  B29C45/34 ,  H01F27/022 ,  Y10S425/812

    摘要： An encapsulated transformer includes a transformer coil assembly, a rigid core insert having an upstanding portion positioned within the hollow interior of the core and a base portion on which the core rests, and a thermoplastic rubber jacket that completely surrounds the transformer coil assembly and is bonded to the base portion of the core insert to provide a completely waterproof encapsulated transformer which is impervious to liquid and gasses that could be detrimental to the performance of the transformer. A method for producing such an encapsulated transformer includes placing a rigid core insert in a mold cavity of a mold, and positioning a transformer coil assembly in the mold cavity so that the transformer coil assembly rests on the core insert. Thermoplastic rubber is then injected into the mold cavity to completely encapsulate the transformer coil assembly in a jacket of thermoplastic rubber. During the injection step, gas in the mold cavity is vented through a vent space provided in the bottom surface of the mold cavity. A mold for encapsulating a transformer coil assembly in thermoplastic rubber includes a bottom mold portion having a mold cavity, an upstanding pin disposed within the mold cavity, a mold cover for closing the mold cavity, and a vent space positioned in the bottom surface of the mold cavity for venting gas within the mold cavity to the exterior of the mold during the injection of thermoplastic rubber into the mold cavity.

    摘要翻译： 封装的变压器包括变压器线圈组件，刚性芯插件，其具有位于芯的中空内部内的直立部分和芯部放置在其上的基部，以及完全围绕变压器线圈组件并结合的热塑性橡胶护套 到芯插入件的基部以提供完全防水的封装变压器，其对于可能对变压器的性能有害的液体和气体是不透水的。 一种用于制造这种封装变压器的方法包括将刚性芯插件放置在模具的模腔中，并将变压器线圈组件定位在模腔中，使得变压器线圈组件搁置在芯插入件上。 然后将热塑性橡胶注入模腔中，以将变压器线圈组件完全包封在热塑性橡胶的夹套中。 在注射步骤期间，模腔中的气体通过设置在模具腔的底表面中的通气空间排出。 用于将变压器线圈组件封装在热塑性橡胶中的模具包括具有模腔的底模部分，设置在模腔内的直立销，用于封闭模腔的模具盖，以及位于 模具腔，用于在将热塑性橡胶注入到模腔中期间将模腔内的气体排出到模具的外部。

    Mass spectrometry apparatus and methods
    5.
    发明授权
    Mass spectrometry apparatus and methods 有权
    质谱仪和方法

    公开(公告)号：US08975579B2

    公开(公告)日：2015-03-10

    申请号：US13582231

    申请日：2011-03-02

    申请人： David Bream ,  Christopher Newman ,  Brian Christopher Webb

    发明人： David Bream ,  Christopher Newman ,  Brian Christopher Webb

    IPC分类号： H01J49/40 ,  H01J49/34 ,  H01J49/44

    CPC分类号： H01J49/34 ,  H01J49/443

    摘要： A mass spectrometer having a mass filter which applies a transient voltage profile to accelerate ion packets. The voltage profile is chosen to have a functional form which imparts each ion species with a kinetic energy which is larger the larger the mass-to-charge ratio and a velocity which is smaller the larger the mass-to-charge ratio. The ions are detected in an ion detector which discriminates between different ion species based on their kinetic energy and taking account of the functional form of the voltage profile. Suitable voltage profiles include periodic functions such as sinusoids, triangles and sawtooths, which allow the amplification of drive pulses in the mass filter to be carried out with narrow band amplification stages, which are simple and inexpensive to construct.

    摘要翻译： 具有质量过滤器的质谱仪，其施加瞬态电压分布以加速离子包。 电压分布被选择为具有赋予每个离子种类具有较大质量 - 电荷比越大的动能的功能形式，并且质量与电荷比越大的速度越小。 在离子检测器中检测离子，其基于它们的动能鉴别不同的离子种类，并考虑到电压分布的功能形式。 合适的电压曲线包括诸如正弦曲线，三角形和锯齿的周期性函数，其允许通过窄带放大级来进行质量滤波器中的驱动脉冲的放大，这是简单且便宜的构造。

    MASS SPECTROMETRY APPARATUS AND METHODS
    6.
    发明申请
    MASS SPECTROMETRY APPARATUS AND METHODS 有权
    质谱仪器和方法

    公开(公告)号：US20120318972A1

    公开(公告)日：2012-12-20

    申请号：US13582231

    申请日：2011-03-02

    申请人： David Bream ,  Christopher Newman ,  Brian Christopher Webb

    发明人： David Bream ,  Christopher Newman ,  Brian Christopher Webb

    IPC分类号： H01J49/26

    CPC分类号： H01J49/34 ,  H01J49/443

    摘要： A mass spectrometer having a mass filter which applies a transient voltage profile to accelerate ion packets. The voltage profile is chosen to have a functional form which imparts each ion species with a kinetic energy which is larger the larger the mass-to- charge ratio and a velocity which is smaller the larger the mass-to-charge ratio. The ions are detected in an ion detector which discriminates between different ion species based on their kinetic energy and taking account of the functional form of the voltage profile. Suitable voltage profiles include periodic functions such as sinusoids, triangles and sawtooths, which allow the amplification of drive pulses in the mass filter to be carried out with narrow band amplification stages, which are simple and inexpensive to construct.

    摘要翻译： 具有质量过滤器的质谱仪，其施加瞬态电压分布以加速离子包。 电压分布被选择为具有赋予每个离子种类的功能形式，其动能越大，质荷比越大，质荷比越大，速度越小。 在离子检测器中检测离子，其基于它们的动能鉴别不同的离子种类，并考虑到电压分布的功能形式。 合适的电压曲线包括诸如正弦曲线，三角形和锯齿的周期性函数，其允许通过窄带放大级来进行质量滤波器中的驱动脉冲的放大，这是简单且便宜的构造。

    PSP-94: use for treatment of hypercalcemia and bone metastasis
    8.
    发明申请
    PSP-94: use for treatment of hypercalcemia and bone metastasis 审中-公开
    PSP-94：用于治疗高钙血症和骨转移

    公开(公告)号：US20050026833A1

    公开(公告)日：2005-02-03

    申请号：US10857358

    申请日：2004-06-01

    申请人： Shafaat Rabbani ,  Nicholas Shukeir ,  Chandra Panchal ,  Christopher Newman

    发明人： Shafaat Rabbani ,  Nicholas Shukeir ,  Chandra Panchal ,  Christopher Newman

    IPC分类号： A61K38/17 ,  C07K14/47 ,  G01N33/574 ,  G01N33/84

    CPC分类号： C07K14/47 ,  A61K38/1709 ,  G01N33/57434 ,  G01N33/84 ,  G01N2333/635 ,  G01N2500/00

    摘要： The present invention discloses the use of PSP-94, PCK3145 and other derivatives and biologically active analogues for treating a patient having a condition such as metastasis, metastatic cancer, a condition associated with elevated levels of parathyroid hormone-related protein (PTHrP), PTHrP-induced osteolysis and/or hypercalcemia of malignancy. These compounds were found to be effective treatment modalities for bone metastasis caused by prostate cancer. Furthermore, decrease in cellular and plasma PTHrP levels as well as plasma calcium levels observed by treatment with such compound can serve as useful biochemical markers for monitoring the efficacy of these anti-metastatic compounds.

    摘要翻译： 本发明公开了使用PSP-94，PCK3145等衍生物和生物活性类似物治疗患有转移，转移性癌症的病人，与甲状旁腺激素相关蛋白（PTHrP）水平升高相关的病症，PTHrP 诱发的骨质溶解和/或恶化的高钙血症。 发现这些化合物是由前列腺癌引起的骨转移的有效治疗方式。 此外，通过用这种化合物治疗观察到的细胞和血浆PTHrP水平以及血浆钙水平的降低可以作为监测这些抗转移化合物的功效的有用的生物化学标记物。

    Media Player Framework
    10.
    发明申请
    Media Player Framework 有权
    媒体播放器框架

    公开(公告)号：US20100235741A1

    公开(公告)日：2010-09-16

    申请号：US12603457

    申请日：2009-10-21

    申请人： Lucas Christopher Newman ,  Charles John Pisula

    发明人： Lucas Christopher Newman ,  Charles John Pisula

    IPC分类号： G06F9/54 ,  G06F3/048

    CPC分类号： G06F9/542 ,  A63F2300/204 ,  A63F2300/6081 ,  G06F3/01 ,  G06F17/30 ,  G06F21/30

    摘要： Systems and methods for managing media playback are described. In one embodiment, a third party media request is received from a third party application. A native media request is sent to a native media player in response to the third party media request. The native media request causes the native media player to access content or metadata. Metadata is returned to the third party application if the third party media request requested data. The native media player performs a content operation on the content if the third party media request requested a content operation.

    摘要翻译： 描述了管理媒体播放的系统和方法。 在一个实施例中，从第三方应用接收第三方媒体请求。 响应于第三方媒体请求，本机媒体请求被发送到本地媒体播放器。 本地媒体请求使本地媒体播放器访问内容或元数据。 如果第三方媒体请求请求的数据，则将元数据返回给第三方应用程序。 如果第三方媒体请求请求内容操作，则本地媒体播放器对内容执行内容操作。