摘要:
A coffee capsule dispensing assembly that includes at least one substantially gelatin casing capsule or composite which contains a coffee concentrate or composite or coffee enhancing substance. The gelatin casing capsule with a hydrolyzed collagen gelatin portion is designed to dissolve in an aqueous solution. A housing assembly with a distal end and a proximal end is designed to contain the at least one gelatin casing capsule. A depressible button assembly is disposed substantially at the proximal end of the housing assembly and is designed to advance the at least one gelatin casing capsule toward the distal end of the housing assembly. A latch and release assembly at the distal end of the housing assembly is designed to singularly release the at least one gelatin casing capsule when the at least one gelatin casing capsule is advanced by the depressible button assembly.
摘要:
The invention described here is a computer-related method for analyzing and reporting the current status of a wide array of processes and conditions across multiple networks and systems. It employs independent software entities called “Blades” to control the retrieval, analysis and characterization of each situation, combined with a common presentation system that displays those characterizations in a simple graphical vocabulary for expressing degrees of positive and negative significance. By employing Tiles or similar independent graphical reports, shown together on the screen of a desktop computer, notebook, tablet, mobile device or wearable interactive display, the invention described here allows the user to see his or her world at a glance.
摘要:
This invention relates to a stereo imaging system for use in telerobotic systems. A method of imaging a target site in a stereo imaging system is provided. The method typically includes capturing a right and a left optical image of the target site and transforming the right and the left optical images preferably into digital information. The method further includes converting the digital information into opposed images of the target site displayed on a stereo display of the stereo imaging system, one of the opposed images being associated with the right optical image and the other of the opposed images being associated with the left optical image. The method further includes regulating the digital information to cause the positions of the target site displayed on the opposed images to change relative to each other. The invention further provides for a method of aligning the opposed images, to a method of adjusting the stereo working distance of an image capture device, such as an endoscope and to a stereo imaging system.
摘要:
The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
摘要:
The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
摘要:
The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
摘要:
The present invention relates to X-ray crystallography studies of a human Janus Kinase 2 (JAK2) domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
摘要:
A compound of general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating kinase-associated disease states using the compound of formula (I) is also described.
摘要:
A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating tyrosine kinase-associated disease states in a subject using a compound of formula (I) is also described.
摘要:
Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.