公开(公告)号：US20130083654A1

公开(公告)日：2013-04-04

申请号：US13625583

申请日：2012-09-24

申请人： Yiu Bun Jack LEE ,  Chi Fung Chan

发明人： Yiu Bun Jack LEE ,  Chi Fung Chan

IPC分类号： H04W28/02 ,  H04W24/00

CPC分类号： H04L43/08 ,  H04L43/0852 ,  H04L43/0864 ,  H04L47/193 ,  H04L47/283 ,  H04W24/08

摘要： A sum-of-delays algorithm in a digital mobile communication bandwidth-varying network is employed to estimate link buffer size and queue length in an undying network connection. In particular, mechanisms associated with the process compensate for link bandwidth variations. In a particular embodiment, passive estimation are employed to implement the process by simply measuring the in-band data packet timings to perform estimation, thus eliminating the need for transmission of extra measurement packets. This method enables the integration of the link buffer size estimation algorithm into existing transport protocols such as TCP to optimize flow and congestion controls. As part of the invention, a new congestion control method called TCP Queue-length-Adaptive (TCP-QA) is developed to employ the sum-of-delays algorithm in the TCP sender computer to control the data flow in a TCP connection. Compared to existing TCP variants, TCP-QA can achieve significantly better network bandwidth utilization in bandwidth-varying networks.

摘要翻译： 采用数字移动通信带宽变化网络中的延迟和求和来估计链路缓冲区大小和排队长度。 特别地，与该过程相关联的机制补偿链路带宽变化。 在特定实施例中，采用无源估计来简单地测量带内数据分组定时来执行估计来实现该过程，从而消除对传输额外测量分组的需要。 该方法使链路缓冲区大小估计算法能够集成到诸如TCP之类的现有传输协议中，以优化流量和拥塞控制。 作为本发明的一部分，开发了一种称为TCP队列长度自适应（TCP-QA）的新的拥塞控制方法，以在TCP发送者计算机中采用延迟求和算法来控制TCP连接中的数据流。 与现有TCP变体相比，TCP-QA可以在带宽变化的网络中实现明显更好的网络带宽利用率。

公开(公告)号：US20120279660A1

公开(公告)日：2012-11-08

申请号：US13100713

申请日：2011-05-04

申请人： Chi Fung CHAN ,  Kin Yik HUNG

发明人： Chi Fung CHAN ,  Kin Yik HUNG

IPC分类号： H05K13/00 ,  B32B38/18 ,  B32B39/00 ,  B32B37/00

CPC分类号： H01L21/67144 ,  Y10T156/17

摘要： An electronic device bonding apparatus comprises a flip arm for picking up an electronic device, the flip arm being operative to invert an orientation of the electronic device. A collet tool which contacts the electronic device and secures it to the flip arm is detachably mountable onto the flip arm, and a bond arm may pick up the electronic device from the collet tool to bond the electronic device to a bonding surface. Additionally, a tool changer module is operative to detach the collet tool from the flip arm and to mount another collet tool onto the flip arm.

摘要翻译： 电子装置接合装置包括用于拾取电子装置的翻转臂，所述翻转臂可操作以反转电子装置的取向。 与电子设备接触并将其固定到翻转臂的夹头工具可拆卸地安装到翻转臂上，并且接合臂可以从夹头工具拾取电子设备以将电子设备接合到接合表面。 此外，工具更换器模块可操作以将夹头工具与翻盖臂分离并将另一夹头工具安装到翻转臂上。

公开(公告)号：US08857486B2

公开(公告)日：2014-10-14

申请号：US13100713

申请日：2011-05-04

申请人： Chi Fung Chan ,  Kin Yik Hung

发明人： Chi Fung Chan ,  Kin Yik Hung

IPC分类号： B32B37/00 ,  H01L21/67

CPC分类号： H01L21/67144 ,  Y10T156/17

摘要： An electronic device bonding apparatus comprises a flip arm for picking up an electronic device, the flip arm being operative to invert an orientation of the electronic device. A collet tool which contacts the electronic device and secures it to the flip arm is detachably mountable onto the flip arm, and a bond arm may pick up the electronic device from the collet tool to bond the electronic device to a bonding surface. Additionally, a tool changer module is operative to detach the collet tool from the flip arm and to mount another collet tool onto the flip arm.

摘要翻译： 电子装置接合装置包括用于拾取电子装置的翻转臂，所述翻转臂可操作以反转电子装置的取向。 与电子设备接触并将其固定到翻转臂的夹头工具可拆卸地安装到翻转臂上，并且接合臂可以从夹头工具拾取电子设备以将电子设备接合到接合表面。 此外，工具更换器模块可操作以将夹头工具与翻盖臂分离并将另一夹头工具安装到翻转臂上。

公开(公告)号：US06607118B2

公开(公告)日：2003-08-19

申请号：US09843704

申请日：2001-04-30

申请人： Chi Wah Cheng ,  Ping Kong Joseph Choy ,  Ping Chun Benson Chong ,  Ka Kin Wong ,  Chi Fung Chan

发明人： Chi Wah Cheng ,  Ping Kong Joseph Choy ,  Ping Chun Benson Chong ,  Ka Kin Wong ,  Chi Fung Chan

IPC分类号： B23K106

CPC分类号： B23K3/0623 ,  B23K35/0244 ,  H01L21/67138 ,  H01L21/6838 ,  H05K3/3478

摘要： There is disclosed a method and apparatus for ensuring release of objects such as solder balls from a pick head in a transfer and placement apparatus, comprising causing said pick head to vibrate by applying a vibration signal to said pick head over a range of frequencies. The range of frequencies is chosen such that it bounds the resonant frequencies of the pick head which may be calculated by computer simulation.

公开(公告)号：US09096831B2

公开(公告)日：2015-08-04

申请号：US13159835

申请日：2011-06-14

申请人： Barbara Pui Chan ,  Hoi Ling Wong ,  Mei Yi Wong ,  Godfrey Chi-Fung Chan ,  Zhen Fan Yang

发明人： Barbara Pui Chan ,  Hoi Ling Wong ,  Mei Yi Wong ,  Godfrey Chi-Fung Chan ,  Zhen Fan Yang

IPC分类号： C12N11/04 ,  C12N5/0775 ,  A61K9/16 ,  A61K35/28 ,  C12N5/0735 ,  C12N5/074 ,  A61K35/12

CPC分类号： C12N5/0663 ,  A61K9/1635 ,  A61K35/28 ,  A61K2035/128 ,  C12N5/0606 ,  C12N5/0665 ,  C12N5/0666 ,  C12N5/0696 ,  C12N11/04 ,  C12N2533/50 ,  C12N2533/54 ,  C12N2533/56 ,  C12N2533/80 ,  C12N2533/90

摘要： A method is provided to functionally select cells with enhanced characteristics relevant to cell engraftment, including both spontaneous migration and directional migration towards specific chemo-attractants. The cells are preferably undifferentiated cells, such as mesenchymal stem cells. The method involves entrapping or encapsulating the cells in a biomaterial barrier, optionally inducing cell migration, and selecting cells that migrated through the barrier. The cells selected by this method have better migratory activities and enhanced in vivo engraftment to injured tissues when they are supplemented systemically.

摘要翻译： 提供了一种方法来功能选择具有与细胞移植相关的增强特征的细胞，包括自发迁移和朝向特定化学引诱物的定向迁移。 细胞优选为未分化细胞，例如间充质干细胞。 该方法包括将细胞包埋或包封在生物材料屏障中，任选地诱导细胞迁移，以及选择通过屏障迁移的细胞。 通过这种方法选择的细胞在系统补充时具有更好的迁移活性和增强的体内植入损伤组织。

公开(公告)号：US08923270B2

公开(公告)日：2014-12-30

申请号：US13625583

申请日：2012-09-24

申请人： Yiu Bun Jack Lee ,  Chi Fung Chan

发明人： Yiu Bun Jack Lee ,  Chi Fung Chan

IPC分类号： H04B7/212 ,  H04L12/26 ,  H04L12/841 ,  H04L12/801 ,  H04W24/08

CPC分类号： H04L43/08 ,  H04L43/0852 ,  H04L43/0864 ,  H04L47/193 ,  H04L47/283 ,  H04W24/08

摘要： A sum-of-delays algorithm in a digital mobile communication bandwidth-varying network is employed to estimate link buffer size and queue length in an undying network connection. In particular, mechanisms associated with the process compensate for link bandwidth variations. In a particular embodiment, passive estimation are employed to implement the process by simply measuring the in-band data packet timings to perform estimation, thus eliminating the need for transmission of extra measurement packets. This method enables the integration of the link buffer size estimation algorithm into existing transport protocols such as TCP to optimize flow and congestion controls. As part of the invention, a new congestion control method called TCP Queue-length-Adaptive (TCP-QA) is developed to employ the sum-of-delays algorithm in the TCP sender computer to control the data flow in a TCP connection. Compared to existing TCP variants, TCP-QA can achieve significantly better network bandwidth utilization in bandwidth-varying networks.

摘要翻译： 采用数字移动通信带宽变化网络中的延迟和求和来估计链路缓冲区大小和排队长度。 特别地，与该过程相关联的机制补偿链路带宽变化。 在特定实施例中，采用无源估计来简单地测量带内数据分组定时来执行估计来实现该过程，从而消除对传输额外测量分组的需要。 该方法使链路缓冲区大小估计算法能够集成到诸如TCP之类的现有传输协议中，以优化流量和拥塞控制。 作为本发明的一部分，开发了一种称为TCP队列长度自适应（TCP-QA）的新的拥塞控制方法，以在TCP发送者计算机中采用延迟求和算法来控制TCP连接中的数据流。 与现有TCP变体相比，TCP-QA可以在带宽变化的网络中实现明显更好的网络带宽利用率。

公开(公告)号：US08734827B2

公开(公告)日：2014-05-27

申请号：US11742040

申请日：2007-04-30

申请人： Barbara Pui Chan ,  Kenneth Man-Chee Cheung ,  Danny Chan ,  Godfrey Chi-Fung Chan ,  Ting Yan Hui

发明人： Barbara Pui Chan ,  Kenneth Man-Chee Cheung ,  Danny Chan ,  Godfrey Chi-Fung Chan ,  Ting Yan Hui

IPC分类号： A61F2/44 ,  C12N5/0775 ,  A61F2/28 ,  A61K38/39

CPC分类号： A61F2/442 ,  A61F2/3094 ,  A61F2002/2817 ,  A61F2002/30006 ,  A61F2002/30016 ,  A61F2002/30153 ,  A61F2002/30677 ,  A61F2002/30971 ,  A61F2002/4445 ,  A61F2002/445 ,  A61F2230/0019 ,  A61F2250/0015 ,  A61F2250/0018 ,  A61F2250/0019 ,  A61F2310/00365 ,  A61K2035/128 ,  A61L27/3633 ,  A61L27/3834 ,  A61L27/3852 ,  A61L27/3856 ,  A61L2430/38 ,  C12N5/0663 ,  C12N2533/54

摘要： A bioengineered IVD for disc replacement has been developed that has mechanical and structural support characteristics similar to those of native IVD. Extracellular matrix (ECM) provides support to living cell components and interacts with the living cellular components during the fabrication process without introducing toxicity. The composition can be produced from both natural or synthetic source but preferably natural and induced to self-assemble or reconstitute into its solid form under conditions that are mild enough to support cellular survival and growth. The cells induce a volume change of the structures, leading to changes in dimension, ECM density, cell density, mechanical property and stability, etc. The extent of the change in volume of the composition can be precisely controlled by factors such as the density of the ECM, the density of the living cells, the timing for interaction and the serum concentration. Increased structural support is provided by crosslinking.

摘要翻译： 已经开发了用于盘替代的生物工程IVD，其具有与天然IVD相似的机械和结构支持特征。 细胞外基质（ECM）在制造过程中提供对活细胞组分的支持和与活细胞组分的相互作用，而不引入毒性。 组合物可以天然或合成来源产生，但优选天然产生，并且在足够温和以支持细胞存活和生长的条件下诱导自组装或重组成其固体形式。 这些细胞诱导结构的体积变化，导致尺寸变化，ECM密度，细胞密度，机械性能和稳定性等。组合物体积变化的程度可以由诸如密度 ECM，活细胞的密度，相互作用的时间和血清浓度。 通过交联提供增加的结构支撑。

公开(公告)号：US08679809B2

公开(公告)日：2014-03-25

申请号：US11750863

申请日：2007-05-18

申请人： Barbara Pui Chan ,  Godfrey Chi-Fung Chan ,  Hoi Ling Wong ,  Pik To Cheung ,  Song-Eng Kathryn Cheah ,  Danny Chan

发明人： Barbara Pui Chan ,  Godfrey Chi-Fung Chan ,  Hoi Ling Wong ,  Pik To Cheung ,  Song-Eng Kathryn Cheah ,  Danny Chan

IPC分类号： C12N11/04

CPC分类号： C12N5/0602 ,  A61K35/12 ,  C12M25/14 ,  C12N5/0012 ,  C12N5/0655 ,  C12N5/0663 ,  C12N2510/02 ,  C12N2533/54 ,  C12N2533/90

摘要： A method has been developed to produce stable cell-matrix microspheres with up to 100% encapsulation efficiency and high cell viability, using matrix or biomaterial systems with poor shape and mechanical stability for applications including cell therapeutics via microinjection or surgical implantation, 3D culture for in vitro expansion without repeated cell splitting using enzymatic digestion or mechanical dissociation and for enhanced production of therapeutic biomolecules, and in vitro modeling for morphogenesis studies. The modified droplet generation method is simple and scalable and enables the production of cell-matrix microspheres when the matrix or biomaterial system used has low concentration, with slow phase transition, with poor shape and mechanical stability.

摘要翻译： 已经开发了一种方法来生产具有高达100％包封效率和高细胞活力的稳定的细胞基质微球，使用具有差的形状和机械稳定性的基质或生物材料体系，包括通过显微注射或手术植入的细胞治疗剂，3D培养物 使用酶消化或机械解离并且用于增强治疗性生物分子的产生的体外扩增而不重复细胞分裂，以及用于形态发生研究的体外模拟。 改进的液滴生成方法简单可伸缩，当使用的基质或生物材料系统具有低浓度，缓慢的相变，形状和机械稳定性差时，能够生产细胞基质微球。

公开(公告)号：US20120148537A1

公开(公告)日：2012-06-14

申请号：US13159835

申请日：2011-06-14

申请人： Barbara Pui Chan ,  Hoi Ling Wong ,  Mei Yi Wong ,  Godfrey Chi-Fung Chan ,  Zhen Fan Yang

发明人： Barbara Pui Chan ,  Hoi Ling Wong ,  Mei Yi Wong ,  Godfrey Chi-Fung Chan ,  Zhen Fan Yang

IPC分类号： A61K35/12 ,  C12N5/02 ,  A61P43/00 ,  C12N5/00

CPC分类号： C12N5/0663 ,  A61K9/1635 ,  A61K35/28 ,  A61K2035/128 ,  C12N5/0606 ,  C12N5/0665 ,  C12N5/0666 ,  C12N5/0696 ,  C12N11/04 ,  C12N2533/50 ,  C12N2533/54 ,  C12N2533/56 ,  C12N2533/80 ,  C12N2533/90

摘要： A method is provided to functionally select cells with enhanced characteristics relevant to cell engraftment, including both spontaneous migration and directional migration towards specific chemo-attractants. The cells are preferably undifferentiated cells, such as mesenchymal stem cells. The method involves entrapping or encapsulating the cells in a biomaterial barrier, optionally inducing cell migration, and selecting cells that migrated through the barrier. The cells selected by this method have better migratory activities and enhanced in vivo engraftment to injured tissues when they are supplemented systemically.

摘要翻译： 提供了一种方法来功能选择具有与细胞移植相关的增强特征的细胞，包括自发迁移和朝向特定化学引诱物的定向迁移。 细胞优选为未分化细胞，例如间充质干细胞。 该方法包括将细胞包埋或包封在生物材料屏障中，任选地诱导细胞迁移，以及选择通过屏障迁移的细胞。 通过这种方法选择的细胞在系统补充时具有更好的迁移活性和增强的体内植入损伤组织。

公开(公告)号：US06766938B2

公开(公告)日：2004-07-27

申请号：US10042829

申请日：2002-01-08

申请人： Chi Wah Cheng ,  Ping Chun Chong ,  Chi Fung Chan ,  Chin Pang Chan

发明人： Chi Wah Cheng ,  Ping Chun Chong ,  Chi Fung Chan ,  Chin Pang Chan

IPC分类号： B23K3102

CPC分类号： B23K3/0623 ,  B23K35/0244 ,  B23K2101/42 ,  H01L21/4853 ,  H05K3/3478

摘要： The invention provides an apparatus and method for positioning solder balls in a desired array on a substrate. A positioning means is provided for positioning the solder balls in positions corresponding to the array of positions the solder balls are to take up on the substrate. A container for receiving a plurality of solder balls and which is movable between a first position remote from the positioning means and a second position directly thereover supplies solder balls to the positioning means. Means are provided to bias the solder balls in the direction of movement of the container from the first to the second position whereby to reduce or obviate damage to the solder balls during such movement.

摘要翻译： 本发明提供了一种用于将焊球定位在基板上的所需阵列的装置和方法。 提供了一种定位装置，用于将焊球定位在与焊球要吸附在衬底上的位置阵列相对应的位置。 一种用于接收多个焊球并且可以在远离定位装置的第一位置和直接在其之间的第二位置移动的容器将焊球提供给定位装置。 提供装置以使焊球从容器的第一位置移动到第二位置，从而减少或消除在这种运动期间对焊球的损坏。